scholarly journals Awareness about Intrathecal Drug Administration among Dental students

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 529-532
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Intrathecal administration includes the immediate infusion of the medication in Cerebro Spinal Fluid(CSF) internal to the intrathecal space of the spinal column. The intrathecal course permits direct medication organization to the CSF by evading the blood-cerebrum hindrance. It permits conveyance of small medication dosages, and the event of adverse effects are decreased compared with systemic courses of medication administration. This survey was performed for assessing the awareness about intrathecal drug administration among dental students. A cross-sectional study was done with a self-administered questionnaire with ten questions circulated among 100 dental students. The questionnaire assessed the awareness about intrathecal drug delivery in medical applications, their medicinal uses, drugs administered, mechanism of action and side effects. The responses were recorded and analysed.17% of the respondents were aware of medical uses of intrathecal drug delivery, 13% were aware of the drugs used in intrathecal drug delivery .10 % were aware of the mechanism of action of intrathecal drug delivery .7% were aware of side effects of intrathecal drug delivery. The awareness about intrathecal drug administration among dental students is not adequate. Increased awareness programs and continuing dental education programs in intrathecal drug delivery should be initiated to improve the awareness levels.

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1005-1008
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Modafinil was initially evolved by a French neurophysiologist Professor Michel Jouvet. Modafinil started with the late 1970s creation of a progression of benzhydryl sulfinyl mixes, including adrafinil that was used in the management of narcolepsy in 1986. Modafinil is fundamentally utilized for its antisomnic function. The aim of the survey is for assessing the awareness of medical applications of Modafinil therapy amongst dental students. A cross-sectional study was done with a self-administered questionnaire with 10 questions circulated among 100 dental students. The questionnaire assessed the awareness about Modafinil therapy in medical applications, their medicinal uses, antisomnic activity, mechanism of action and side effects. The responses were recorded and analysed. 94 % of the respondents were not aware of medical uses of Modafinil therapy .83 % were not aware of antisomnic activity therapy. 90 % were not aware of the mechanism of action of Modafinil therapy. 85% were not aware of the side effects of Modafinil therapy. The awareness about the use of Modafinil therapy in medical applications is very less among dental students. Increased awareness programs and sensitization and continuing dental education programs along with greater importance to the curricular modifications should be incorporated to improve the awareness levels.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1095-1098
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Cryotherapy is the use of cold for either the management of injury or illness, has become common across sports medicine. It remains a well-established procedure for managing serious soft tissue damages. However, there is the disparity between both the theoretical evidence for cryotherapy in clinical trials. This survey was performed for assessing the awareness about cryotherapy in sports medical applications amongst dental students. A cross-sectional study was done with a self-administered questionnaire with 10 questions circulated among 100 dental students. The questionnaire assessed the awareness about cryotherapy in sports medical applications, their medicinal uses, anti-inflammatory activity, mechanism of action and side effects. The responses were recorded and analysed. 87% of the respondents were not aware of medical uses of Cryotherapy.73% were not aware of the anti-inflammatory activity of Cryotherapy.83 % were not aware of the mechanism of action of Cryotherapy. 85% were not aware of the side effects of Cryotherapy. The awareness about the use of cryotherapy in sports medical applications is very less among dental students. Increased awareness programs and sensitization and continuing dental education programs along with greater importance to the curricular modifications in sports dentistry should be incorporated to improve the awareness levels.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 942-945
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Interferon is perhaps the term given to antiviral material formed by many vertebrate cells in reaction to viral infections. Research has established a number of mechanisms involved, in therapeutic benefits of interferon together with antiviral, innate immunity-enhancing and functions. This survey was performed for assessing the awareness about interferon therapy amongst dental students. A cross-sectional survey was performed with a self-administered questionnaire with ten queries circulated among 100dental students. The questionnaire assessed the awareness about Interferon therapy, their medicinal uses, anticancer activity, mechanism of action and side effects. The responses were recorded and .91% of the respondents were not aware of medical uses of Interferon therapy .93%were not aware of anticancer activity of Interferon therapy.93 % were not aware of the mechanism of action of Interferon therapy .96% were not aware of side effects of Interferon therapy. The awareness about the use of interferon therapy is very less among dental students. Increased awareness programs and sensitization programs should be conducted to improve the awareness levels.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1009-1012
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Ozone (O3) happens to be a triple atomic particle that comprises three oxygen iotas with an atomic load of 47.98 g/mol. Ozone is a thermokinetic coseismal particle which, contingent upon framework conditions like temperature and weight, has a short half-life and breaks down into sub-atomic oxygen (O2). Ozone is utilized as medication in many conditions. The study aimed to assess the awareness of medical applications of ozonated water therapy among dental students. A cross sectional study was done with a self-administered questionnaire with 10 questions circulated among 100 dental students. The questionnaire assessed the awareness about ozone water therapy in medical applications, their medicinal uses, antiinflammatory activity, mechanism of action and side effects. The responses were recorded and analysed.87% of the respondents were not aware of medical uses of Ozone water therapy .73% were not aware of antiinflammatory activity of Ozone water therapy.83 % were not aware of the mechanism of action of Ozone water therapy .85% were not aware of side effects of Ozone water therapy. The awareness about the use of Ozone water therapy in medical applications is very less among dental students. Increased awareness programs and sensitization and continuing dental education programs along with greater importance to the curricular modifications should be incorporated to improve the awareness levels.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 541-544
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

QL47 a Bruton Tyrosine Kinase inhibitor is a host-targeted, small molecule antiviral that inhibits steady-state viral protein expression. This small molecule broadly inhibits both viral and host protein synthesis and targets a translation step specific to eukaryotic cells and has the potential to be used as an antiviral medication. The aim of the study was to assess the awareness about medical applications of QL-47 among dental students. This was a questionnaire-based cross-sectional type of study comprising 100 dental college students in Chennai. A self-designed questionnaire with ten questions eliciting the knowledge and awareness about QL 47 therapy among dental college students. Questionnaires were circulated through an online website survey planets questions explored the awareness on QL 47 therapy, indications, contraindications, mechanism of action and side effects. After the responses were received from 100 participants, data were collected and analysed.5% were aware about QL 47 therapy. 3% were aware of the mechanism of action of QL 47 therapy. 4% were aware of the indications of QL 47 therapy. 3% were aware of the QL 47 therapy.3%.were aware of the side effects of QL 47 therapy. The awareness about QL 47 in medical applications and managing viral infections was less among dental students. Increased awareness and educational programs should be initiated to spread knowledge about QL 47 therapy.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 937-941
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

Herbal medicines reflect a significant portion of new interest in alternative therapies and Ginkgo biloba (GB) features significantly throughout this regard. The GB concentrate and any of its constituents are already thoroughly researched in terms of its impact on behavioral, physiological and psychological consequences linked with neurological and vascular conditions. The purpose of this survey was for assessing the awareness of medical applications of Gingko Biloba amongst dental students. A cross-sectional survey was conducted with a self-administered questionnaire with 10 queries circulated among 100 dental students. The questionnaire assessed the awareness about Ginkgo bilobatherapy in medical applications, their anti-dementia properties, anti alziemer properties, anti-ageing activity, anti-inflammatory activity, and its mechanism of action and side effects. The responses were recorded and analysed.8% of the respondents were aware of the medical applications of Gingko Biloba therapy.6 % were aware of the anti-dementia activity of Gingko Biloba therapy,5% were aware of anti alziemer properties of Gingko Biloba therapy,6% were aware of anti-ageing properties of Gingko Biloba therapy, 5% were aware of anti-inflammatory properties of Gingko Biloba therapy, 5% were aware mechanism of action and side effects of Gingko Biloba therapy. The awareness about the usage of Ginkgo biloba therapy in medicinal applications is low among dental students. Increased awareness programs and sensitization and continuing dental education programs along with greater importance to the curricular modifications, can further enhance knowledge and awareness about Ginkgo biloba therapy.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 705-709
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy

A coronavirus is indeed a group of viruses which inflict a variety of dangerous human diseases including the common cold and far more extreme types such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The medical emergency caused due to SARS-CoV-2 coronavirus (COVID-19) throughout the city of Wuhan, China, is now a pandemic that has spread to nearly 200 countries. Over several million people globally were already diagnosed with the new coronavirus SARS-CoV-2. This survey was performed for assessing the awareness about convalescent plasma therapy in managing COVID-19 amongst dental students. A questionnaire oriented cross-sectional type of survey was done in a group comprising 100 dental college students in Chennai. A self-designed questionnaire contains 10 questions based on the knowledge and awareness about Convalescent Plasma therapy among dental college students. Questionnaires were circulated through an online website survey planet. The questions explored the awareness of Convalescent Plasma therapy, indications, contraindications, mechanism of action and side effects. After the responses were received from 100 participants, data were collected and analyzed. 9% are aware of Convalescent Plasma therapy. 15% are aware of the mechanism of action of Convalescent Plasma therapy. 15% are aware of the indications of Convalescent Plasma therapy. 13% are aware of the contraindications of Convalescent Plasma therapy. 11%. are aware of the side effects of Convalescent Plasma therapy. The awareness about convalescent plasma therapy was less among dental students. Increased awareness and educational programs should be initiated to spread knowledge about plasma therapy.


Author(s):  
Juan M. Carmona ◽  
Ana M. Baena ◽  
Ana C. Berral ◽  
Quintiliano Sotelo ◽  
Beatriz Recio ◽  
...  

The objective of this study was to determine the knowledge of health professionals Hospital of Montilla on the administration of drugs in emergencies. Material: cross-sectional descriptive study conducted at the Hospital of Montilla (Córdoba). A questionnaire to doctors and nurses were distributed by random sampling during the month of December 2014. A survey of Machado de Azevedo et al. (2012) that consists of 9 items for the assessment of knowledge on medication administration was used. Results: The sample was composed of 59.1% of physicians and 40.9% of nurses with an average age of 38.05 (SD±8.981). Regarding the situation of respondents, 72.7% had received prior training. Regarding their own self-assessment, 72.7% considered to have a satisfactory knowledge of drug administration. 90.9% of respondents known to exist protocols on the administration of drugs in his unit. Discussion: Although the knowledge of drug delivery is acceptable for health workers, there are differences between the two analyzed collectives. Therefore, it would be ideal to perform adequate training and retraining of staff for optimal knowledge and, in this way, improve health care.


2013 ◽  
Vol 2;16 (2;3) ◽  
pp. E107-E111
Author(s):  
Thomas Chai

Intrathecal drug delivery is a mode of analgesic delivery that can be considered in those experiencing both refractory pain and excessive side effects from opioid and adjuvant analgesic use. Delivery of analgesic agents directly to the cerebral spinal fluid allows binding of the drug to receptors at the spinal level. Therefore, a reduced analgesic dosage can be afforded, resulting in reduction of drug side effects due to decreased systemic absorption. Drug delivery into the intrathecal space provides this benefit, yet it does not eliminate the possibility of drug side effects or risks of complications. Complications from this route of administration may be seen in the perioperative period or beyond, including infection, inflammatory mass, bleeding, and catheter or pump dysfunction, among others. This may manifest as new/worsening pain or as a neurologic deficit, such as a sensorimotor change and bladder/bowel dysfunction. Urgent evaluation with a detailed physical examination, device interrogation, and other workup including imaging is called for if symptoms suspicious for device-related problems arise. For the cancer pain patient, the underlying malignancy should also be considered as a potential cause for these new symptoms after intrathecal system implantation. We present 2 such cases of complications in the cancer pain patient after intrathecal drug delivery due to progression of the underlying malignant process rather than to surgical or device-related problems. The first patient had a history of metastatic osteosarcoma who, shortly after undergoing an intrathecal drug delivery trial with external pump, presented with new symptoms of both pain and neurologic changes. The second patient with a history of chondrosarcoma developed new symptoms of pain and sensorimotor change several days after intrathecal drug delivery system implantation. Key words: Intrathecal analgesia, intrathecal drug delivery, perioperative complications, cancer pain, malignant pain, pain pump


Author(s):  
Dalal Salem Al- Dossari ◽  
Mohammed Ibrahim Alnami ◽  
Naseem Akhtar Qureshi

Background: Drug prescription error is a medication error that most frequently happens in healthcare organizations and adversely affects the healthcare consumers. Most medication errors (MEs) but not all are captured and corrected before reaching the patient by designed system controls. Medication administration errors (MAEs) mostly are made by nurses but frequently reported by clinical pharmacists in hospitals in Saudi Arabia. Objective: This study aimed to analyze exclusively the voluntarily reported drug administration errors in a tertiary care hospital in Riyadh city. Methods: This cross-sectional, retrospective study evaluated consecutively collected medication administration report forms over a period of one year from January 1, 2015 to December 31, 2015. Results: The number of MAEs occurring during stage of drug administration constituted 7.1% (n=971) of total medication errors (n=13677). The maximum number of MEs (n=6838, 50%) and MAEs (n=455, 46.9%) occurred during the 4th quarter of the year 2015. The most common MAE happened to be category C (n=888, 91.5%) which means error occurred, reached the patient but without causing any harm. Concerning MAE types, the most common error included wrong frequency (40%) followed by wrong drug (17%), wrong time of administration (16%) and wrong rate of infusion (10%). Nurses made the most of the errors (92.2%) while the clinical pharmacists reported the most MAEs (75.5%). High alert medications (HAM) errors constituted 32.3% (n=314) of MAEs (n=971) and most common HAM errors included the wrong route of administration of Lanus Insulin (15%) followed by Insulin Aspart (15%), Enoxaparin (13%) and Insulin Protamine-Nvomix (12%). Look-alike and sound-alike (LASA) errors constituted 55.2% of MAEs (971/536) and most common LASA drugs identified were Gentamycin (13%), Insulin Mixtard (11%), NPH Insulin (8%) Intralipid vial (8%) and Insulin regular (6%). Conclusion: This retrospective study provides some important tentative pharmacovigilance insights into MAEs, which are partially comparable with current international trends in drug administration errors. Further studies on MAEs are warranted not only in the Kingdom of Saudi Arabia but also other Gulf countries.


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