Anti-hyperlipidemic effects of citrus fruit peel extracts against high fat diet-induced hyperlipidemia in rats

The effects of extracts of orange, , lime, citron and sour orange fruit peels (250 and 500 mg kg-1, i.p) were tested in high fat diet-fed rats. The extracts of lime and sour orange peels (250 and 500 mg kg-1, i.p) showed potent effects, as evident by the decreases in total cholesterol (TC), triglycerides (TG), LDL-C, and VLDL-C, in addition to the increases in HDL-C levels. Besides, lime and sour orange peels (250 and 500 mg kg-1) extract significantly decreased LDL-C/HDL-C ratio, while lime, sour orange and peel extracts markedly decreased index. Remarkably, lime peel extract followed by sour orange and orange at 500 mg kg-1 improved hepatic architecture to near normal with less deposition of fat globules and fewer. Altogether, lime and sour orange peel extracts were found to be effective against parameters such as TC, TG, LDL-C, VLDL-C, and TC/HDL-C and LDL-C/HDL-C ratios, and index, in addition to the increased levels of HDL-C. Thus, lime and sour orange peel extracts could be natural supplement in the management of and associated diseases.

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Potential Effect of Sour Orange Peel (Citrus Aurantium) Supplementation on Lipid Profile and Liver Function of Albino Rats Fed on High Fat Diet

Egyptian Journal of Nutrition ◽

10.21608/enj.2019.144749 ◽

2019 ◽

Vol 34 (3) ◽

pp. 93-111

Keyword(s):

Liver Function ◽

Lipid Profile ◽

High Fat Diet ◽

Orange Peel ◽

Potential Effect ◽

Albino Rats ◽

Sour Orange ◽

Citrus Aurantium ◽

High Fat

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Thermal, Physical and Mechanical Performance of Orange Peel Boards: A New Recycled Material for Building Application

Sustainability ◽

10.3390/su13147945 ◽

2021 ◽

Vol 13 (14) ◽

pp. 7945

Author(s):

Matteo Vitale ◽

María del Mar Barbero-Barrera ◽

Santi Maria Cascone

Keyword(s):

Thermal Conductivity ◽

Bending Strength ◽

Mechanical Performance ◽

Orange Peel ◽

Insulation Material ◽

Orange Peels ◽

Orange Fruit ◽

Citrus Waste ◽

Absorption Thickness ◽

Loss Of Strength

More than 124 million tons of oranges are consumed in the world annually. Transformation of orange fruit generates a huge quantity of waste, largely composed of peels. Some attempts to reuse by-products derived from citrus waste have been proposed for energy production, nutrient source or pharmaceutical, food and cosmetic industries. However, their use in the building sector had not been researched. In this study, orange peels, in five different ratios, from 100% of wet peels to 75% and from 0% of dry peels to 25%, were submitted to a thermo-compression procedure. They were evaluated according to their physical (bulk density, water absorption, thickness swelling, surface soundness and thermal conductivity) and mechanical properties (bending strength and modulus of elasticity). The results showed that orange peels can be used as thermal insulation material. The addition of dried peels makes the structure of the board heterogeneous and thus increases its porosity and causes the loss of strength. Hence, the board with the sole use of wet peel, whose thermal conductivity is 0.065 W/mK while flexural strength is 0.09 MPa, is recommended.

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PENGARUH PEMBERIAN BERBAGAI KULIT JERUK SEBAGAI REPELENSI KUTU BERAS (Sitophilus oryzae L.) DAN SUMBANGSIHNYA PADA MATERI HAMA DAN PENYAKIT PADA TANAMAN DIKELAS VIII

Bioilmi Jurnal Pendidikan ◽

10.19109/bioilmi.v4i2.2883 ◽

2018 ◽

Vol 4 (2) ◽

pp. 110-122

Author(s):

Desma Susanti ◽

Choirun Niswah ◽

Riri N Sunarti

Keyword(s):

Sitophilus Oryzae ◽

Orange Peel ◽

Anova Analysis ◽

Factor B ◽

Descriptive Research ◽

Orange Peels ◽

Data Collection Process ◽

Class Viii ◽

Quantitative Descriptive ◽

Lime Peel

This study entitled the effect of giving various orange peels as a repelence of rice lice (Sitophillusoryzae L.) and its contribution to pest and disease material in plants in class VIII. This study aims todetermine the effectiveness of various orange peels as a repelence of what type of rice lice andorange skin is most effectively used as a repelence of rice lice. The type of research used in thisstudy is quantitative descriptive research (where the data collection process uses statistical analysis)and the experimental method. The data obtained were analyzed statistically using Analysis ofVarience (ANOVA). Analysis of the variance of the treatment effects for a complete randomizeddesign (CRD) was carried out according to the F test. Based on the results of the research, eachtreatment was significantly different from the control. The highest percentage of rejection wasfound in the treatment of lime peel, which amounted to 56.25 at 76 hours and the lowest percentagewas found in the treatment of sunkist orange peel ie 27.5 at 76 hours. Hypothesis testing results forF count treatment (19> 1.79) and F count Factor A (40> 2.99) and F count on Factor B (102> 3.20),this states that slices of various orange peels (Citrus sp.) very significant effect to reject riceinfestation (Sitophillus oryzae L.), so that it is stated that H1 is accepted and H0 is rejected. Thus itcan be concluded that various citrus coolies are effective as repelensi rice mites (Sitophillus oryzaeL.).

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Camellia sinensis fruit peel extract inhibits angiogenesis and ameliorates obesity induced by high-fat diet in rats

Journal of Functional Foods ◽

10.1016/j.jff.2014.01.008 ◽

2014 ◽

Vol 7 ◽

pp. 479-486 ◽

Cited By ~ 11

Author(s):

Narendra Chaudhary ◽

Jyoti Bhardwaj ◽

Hyo Jin Seo ◽

Min Yong Kim ◽

Tai Sun Shin ◽

...

Keyword(s):

Camellia Sinensis ◽

High Fat Diet ◽

High Fat ◽

Fruit Peel ◽

Peel Extract

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Recovery of pure Hesperidin from Iraqi Sweet Oranges Peel and study the effect in some bacteria

Baghdad Science Journal ◽

10.21123/bsj.11.2.455-460 ◽

2014 ◽

Vol 11 (2) ◽

pp. 455-460 ◽

Cited By ~ 3

Author(s):

Baghdad Science Journal

Keyword(s):

Antimicrobial Activity ◽

Inhibitory Concentration ◽

Citrus Fruit ◽

Orange Peel ◽

Salmonella Typhi ◽

High Concentration ◽

Fruit Peel ◽

Hplc Technique ◽

Orange Peel Extract ◽

Peel Extract

Citrus fruit contain variety of flavonoids such as Hesperidin (the principal flavonoid in oranges and grapefruit). Hesperidin is found in high concentration in fruit peel of oranges and in substantially lower concentration in juice of these fruits. Hesperidin was extracted from oranges peel by treating the peels with calcium hydroxide. HPLC technique was used to determine hesperidin. Hesperidin was saperated and purified in a purity of about 90.1-95.7% and yield about 1.5 %w/w from oranges peel dry powder. Both hesperidin and oranges peel extract showed significan antibacterial activity. Sensitivity to hesperidin and oranges peel extracts were not similar for the chosen bacteriaCrude orange peel extract gave a various antimicrobial activity agents Gram-positive Bacillus cereus, Staphylococcus aurous, Streptococcus pyogenus sp. and Gram-negative (Escherichia coli, Salmonella typhi) bacteria strains`. The minimum inhibitory concentration (MIC) values against these bacteria ranged from 45-175?g/disc.for crude orange peel extractand 175-450?g/disc for pure hesperidin In comparison to 30?g/disc reference standards ciproflaxacin and impinme.orange peel extract showed significant antimicrobial activity.

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Anti-Obesity Effects of Matoa (Pometia pinnata) Fruit Peel Powder in High-Fat Diet-Fed Rats

Molecules ◽

10.3390/molecules26216733 ◽

2021 ◽

Vol 26 (21) ◽

pp. 6733

Author(s):

Toshikazu Suzuki ◽

Mayumi Nagata ◽

Natsuko Kagawa ◽

Shiori Takano ◽

Nahrowi ◽

...

Keyword(s):

Body Weight ◽

Visceral Fat ◽

High Fat Diet ◽

Antioxidant Properties ◽

Serum Triglyceride ◽

Inhibitory Effect ◽

The Body ◽

High Fat ◽

Fruit Peel ◽

Hepatic Lipid

Fruit peels, pericarps, or rinds are rich in phenolic/polyphenolic compounds with antioxidant properties and potentially beneficial effects against obesity and obesity-related non-communicable diseases. This study investigated the anti-obesity effects of matoa (Pometia pinnata) and salak (Salacca zalacca) fruit peel. Neither matoa peel powder (MPP) nor salak peel powder (SPP) affected the body weight, visceral fat weight, or serum glucose or lipid levels of Sprague–Dawley rats when included as 1% (w/w) of a high-fat diet (HFD). However, MPP significantly decreased the hepatic lipid level. MPP at a dose of 3% (w/w) of the HFD decreased body weight, visceral fat, and serum triglyceride levels as well as the hepatic lipid content. The inhibitory effect of MPP on hepatic lipid accumulation was not enhanced when its concentration was increased from 1% to 3% of the HFD. The anti-obesity effect of matoa was partly explained by the inhibitory effect of the matoa peel extract on fatty acid-induced secretion of ApoB-48 protein, a marker of intestinal chylomicrons, in differentiated Caco-2 cell monolayers. We identified hederagenin saponins that are abundant in MPP as potential anti-obesity substances. These results will contribute towards the development of functional foods with anti-obesity effects using the matoa fruit peel.

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Abstract # P-20: 11b-Hydroxysteroid Dehydrogenase 1 Regulation in High Fat Diet Induced Insulin Resistant Rats and Rats Treated with Sutherlandia Frutescens

Endocrine Practice ◽

10.1016/s1530-891x(20)43833-9 ◽

2016 ◽

Vol 22 ◽

pp. 23

Author(s):

Ngozi F. Nnolum-Orji ◽

Saartjie Roux ◽

Janine Mackenzie ◽

Disang Lekutlane

Keyword(s):

High Fat Diet ◽

Hydroxysteroid Dehydrogenase ◽

High Fat ◽

Insulin Resistant ◽

Sutherlandia Frutescens

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Effects of Maternal Flaxseed Supplementation on Female Offspring of Diabetic Rats in Serum Concentration of Glucose, Insulin, and Thyroid Hormones

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000259 ◽

2019 ◽

Vol 89 (1-2) ◽

pp. 45-54

Author(s):

Akemi Suzuki ◽

André Manoel Correia-Santos ◽

Gabriela Câmara Vicente ◽

Luiz Guillermo Coca Velarde ◽

Gilson Teles Boaventura

Keyword(s):

Thyroid Hormones ◽

High Fat Diet ◽

Female Offspring ◽

Flaxseed Oil ◽

Diabetic Rats ◽

High Fat ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Flaxseed Flour ◽

Maternal Consumption

Abstract. Objective: This study aimed to evaluate the effect of maternal consumption of flaxseed flour and oil on serum concentrations of glucose, insulin, and thyroid hormones of the adult female offspring of diabetic rats. Methods: Wistar rats were induced to diabetes by a high-fat diet (60%) and streptozotocin (35 mg/kg). Rats were mated and once pregnancy was confirmed, were divided into the following groups: Control Group (CG): casein-based diet; High-fat Group (HG): high-fat diet (49%); High-fat Flaxseed Group (HFG): high-fat diet supplemented with 25% flaxseed flour; High-fat Flaxseed Oil group (HOG): high-fat diet, where soya oil was replaced with flaxseed oil. After weaning, female pups (n = 6) from each group were separated, received a commercial rat diet and were sacrificed after 180 days. Serum insulin concentrations were determined by ELISA, the levels of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were determined by chemiluminescence. Results: There was a significant reduction in body weight at weaning in HG (−31%), HFG (−33%) and HOG (44%) compared to CG (p = 0.002), which became similar by the end of 180 days. Blood glucose levels were reduced in HFG (−10%, p = 0.044) when compared to CG, and there was no significant difference between groups in relation to insulin, T3, T4, and TSH after 180 days. Conclusions: Maternal severe hyperglycemia during pregnancy and lactation resulted in a microsomal offspring. Maternal consumption of flaxseed reduces blood glucose levels in adult offspring without significant effects on insulin levels and thyroid hormones.

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