scholarly journals The morphology of the elements of the myocardial contractile apparatus question and research prospects

Morphologia ◽  
2021 ◽  
Vol 15 (2) ◽  
pp. 68-76
Author(s):  
P.A. Kobeza
Keyword(s):  
Spatial Structure ◽  
Research Methods ◽  
Spatial Organization ◽  
Information Sources ◽  
Meta Analysis ◽  
Morphological Characteristics ◽  
Contractile Apparatus ◽  
Immunohistochemical Markers ◽  
Myocardial Contractile ◽  
Species Specific

Background. Over the past 50 years, specific methods for studying the ultrastructure of the heart have been rapidly developed. The complex interaction of various research methods makes it possible to more accurately form a representation of the spatial structure of the components of the myocardial contractile apparatus. Objective. To conduct a content analysis of the results of the study of the composition of the myocardial contractile apparatus. Conduct a broad analysis of literary references and form an understanding of the spatial structure of the components of the myocardial contractile apparatus in the prospect of research at different levels of cell organization. Methods. Processing of information sources was carried out by the method of complex meta-analysis of data analysis. Results. The morphological characteristics of the myocardial contractile apparatus include a number of broad profile elements. The system of composite elements of the contractile apparatus of cardiomyocytes is the most formed and developed in the structure of the cytoplasmic complex of organelles in the group of contractile cardiomyocytes. The complex of the contractile apparatus is represented by myofibrils, each of which consists of thousands of sarcomeres telophragm connected in series, containing actin (thin) and myosin (thick) myofilaments. The main methods for studying the contractile apparatus of the myocardium include how immunohistochemistry and transmission electron microscopy provide an understanding of the structure of components at various levels of organization of histoarchitectonics and ultrastructure of organelles.. The contractile apparatus of the myocardium includes species-specific organelles, which basically belong to a number of basic hardware systems of cardiomyocytes. Conclusion. Immunohistochemical methods should clearly show the localization of individual tipes of elements in the protein structure of the contractile apparatus of the myocardium, and therefore should include in the study methods the use of the following immunohistochemical markers that can show the configuration of thin and thick myofilaments. The results of analytical review and analysis of information sources on the characteristics of the components of the myofibrillar complex gives a choice of specific research methods and forms a more detailed understanding of the spatial organization of the morphology of the myocardial contractile apparatus.

Cattle Review

Livestock ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 194-194
Author(s):  
David C Barrett
Keyword(s):  
Research Methods ◽  
Meta Analysis ◽  
Dairy Farms ◽  
Antimicrobial Use ◽  
Veterinary Students ◽  
Students Attitudes

Introduction: In this Cattle Review we consider a meta-analysis of dietary cation-anion difference research, methods of measuring antimicrobial use on dairy farms, and UK veterinary students' attitudes towards production animal orientated careers.

scholarly journals Characterization of the Bull's Eye Rot of Apple in Chile

Plant Disease ◽  
2013 ◽  
Vol 97 (4) ◽  
pp. 485-490 ◽  
Author(s):  
Sylvana Soto-Alvear ◽  
Mauricio Lolas ◽  
Inés M. Rosales ◽  
Eduardo R. Chávez ◽  
Bernardo A. Latorre
Keyword(s):  
Morphological Characteristics ◽  
The United States ◽  
Apple Fruit ◽  
Maritime Transportation ◽  
Tubulin Genes ◽  
Internal Transcribed Spacer Sequences ◽  
Apple Production ◽  
Species Specific ◽  
Bull's Eye

Apple fruit in Chile are primarily produced for export to Asia, Europe, and the United States, which typically requires 15 to 40 days of maritime transportation. Therefore, Chilean apple production must fulfill the sanitization requirements imposed by the receiving countries. Under these circumstances, it was important to clarify the etiology of bull's eye rot that can severely affect ‘Cripps Pink’ apple and other late-harvest cultivars in Chile. Based on morphological characteristics and the partial sequence analysis of the internal transcribed spacer sequences and β-tubulin genes, Neofabraea alba was identified as the causal agent of the bull's eye rot of Chilean apple. These results were further corroborated using species-specific primers. The incidence of bull's eye rot varied considerably; for instance, in 2009, 0.0 to 58.7% in 38 Cripps Pink orchards surveyed in the relatively arid and humid apple-growing areas of Chile, respectively. There was no evidence for the presence of N. malicorticis or N. perennans, which are commonly identified as causal agents of bull's eye rot in other apple-producing countries. Altogether, these data suggest that N. alba might represent the predominant and possibly the only cause of bull's-eye rot of Chilean apple.

scholarly journals Spatial and Temporal Features of the Growth of a Bacterial Species Colonizing the Zebrafish Gut

mBio ◽  
2014 ◽  
Vol 5 (6) ◽  
Author(s):  
Matthew Jemielita ◽  
Michael J. Taormina ◽  
Adam R. Burns ◽  
Jennifer S. Hampton ◽  
Annah S. Rolig ◽  
...  
Keyword(s):  
Fluorescence Microscopy ◽  
Spatial Structure ◽  
Growth Kinetics ◽  
Spatial Organization ◽  
Temporal Dynamics ◽  
Bacterial Species ◽  
Bacterial Load ◽  
Light Sheet ◽  
Logistic Growth ◽  
Light Sheet Fluorescence Microscopy

ABSTRACTThe vertebrate intestine is home to microbial ecosystems that play key roles in host development and health. Little is known about the spatial and temporal dynamics of these microbial communities, limiting our understanding of fundamental properties, such as their mechanisms of growth, propagation, and persistence. To address this, we inoculated initially germ-free zebrafish larvae with fluorescently labeled strains of anAeromonasspecies, representing an abundant genus in the zebrafish gut. Using light sheet fluorescence microscopy to obtain three-dimensional images spanning the gut, we quantified the entire bacterial load, as founding populations grew from tens to tens of thousands of cells over several hours. The data yield the first ever measurements of the growth kinetics of a microbial species inside a live vertebrate intestine and show dynamics that robustly fit a logistic growth model. Intriguingly, bacteria were nonuniformly distributed throughout the gut, and bacterial aggregates showed considerably higher growth rates than did discrete individuals. The form of aggregate growth indicates intrinsically higher division rates for clustered bacteria, rather than surface-mediated agglomeration onto clusters. Thus, the spatial organization of gut bacteria both relative to the host and to each other impacts overall growth kinetics, suggesting that spatial characterizations will be an important input to predictive models of host-associated microbial community assembly.IMPORTANCEOur intestines are home to vast numbers of microbes that influence many aspects of health and disease. Though we now know a great deal about the constituents of the gut microbiota, we understand very little about their spatial structure and temporal dynamics in humans or in any animal: how microbial populations establish themselves, grow, fluctuate, and persist. To address this, we made use of a model organism, the zebrafish, and a new optical imaging technique, light sheet fluorescence microscopy, to visualize for the first time the colonization of a live, vertebrate gut by specific bacteria with sufficient resolution to quantify the population over a range from a few individuals to tens of thousands of bacterial cells. Our results provide unprecedented measures of bacterial growth kinetics and also show the influence of spatial structure on bacterial populations, which can be revealed only by direct imaging.

Meta-analysis of transactional and financial possibilities of using trade credit

2015 ◽  
Vol 60 (7) ◽  
pp. 51-73
Author(s):  
Natalia Nehrebecka ◽  
Anna Białek-Jaworska ◽  
Aneta Dzik-Walczak
Keyword(s):  
Research Methods ◽  
International Research ◽  
Logit Model ◽  
Trade Credit ◽  
Meta Analysis ◽  
Debt Financing ◽  
Company Size ◽  
Growth Opportunities ◽  
Funding Sources

Article aims to systematize the knowledge acquired in the independent international research on the determinants of financing enterprises using trade credit by conducting a meta-analysis for the main groups of factors taken into account in the models: debt, liquidity, company size, profitability, stocks and growth opportunities. On the basis of publications review devoted to funding sources, 26 companies using trade credit from suppliers are selected. A database containing information about 232 of the estimated models is built. A logit model is estimated to identify the characteristics of trials and research methods determinants influencing the importance of trade credit finance companies. Results of the effect of debt financing on commercial credit utilization depend on the country and the characteristics of surveyed enterprises.

scholarly journals Research of urban agglomerations in the aspect of implementation of the administrative and territorial reform in Ukraine (case study of Kharkiv region)

2019 ◽  
Keyword(s):  
Spatial Structure ◽  
Spatial Organization ◽  
Weighted Average ◽  
Evolutionary Potential ◽  
Statistical Parameters ◽  
Urban Agglomerations ◽  
Territorial Structure

In the modern context of, one of the main tasks in the regional development management is to optimally realize the complex potential of the territories, which requires a comprehensive study of the spatial structure and evolutionary potential of agglomerations of all levels in order to identify disparities in their development, correct imbalances and optimize the spatial organization of the region. The first step to solve this problem is to identify the spatial structure and evaluate the interconnections of agglomerations sequentially, from local to regional level. This is becoming more relevant in the context of administrative and territorial reform in Ukraine. The purpose of this study is to analyze the prospects for the development of urban agglomerations and the organization of the administrative and territorial structure of Kharkiv region in view of the prevailing influence of the city of Kharkiv and the Kharkiv agglomeration. The basic theoretical and methodological starting points of the study of urban agglomerations are presented; their characteristics and parameters of boundary determination were defined. The essence of the method of modeling of integral influence function (IIF modeling) was revealed, the author's research methodology was substantiated. The tendencies of introduction of administrative and territorial reform in Ukraine were analyzed. It was established that Kharkiv region occupies mediocre places in terms of formation of the united territorial communities, there were 23 ones in the oblast (3 of them are city, 12 town, 8 rural ones) by the end of 2019. The scheme for dividing into enlarged districts has not yet been approved. According to different plans / proposals, the existing 27 districts of the oblast should be consolidated into nine, seven, six or four enlarged districts (counties). All of the above proposals were considered by the authors, it is established that the existing projects do not fully cover the main prevailing factors of allocation of competitive districts, do not take into account the role of historically formed system of settlement, spatial-statistical parameters, integral potential of territories, urbanization and agglomeration. The authors performed the IIF modeling and constructed the IIF surface of the weighted average settlement potential of Kharkiv region by the base radius of influence (2, 10, 20, and 30 km), which allowed to determine the features of the Kharkov agglomeration structure and the interaction of the settlements in the region by different radiuses of interaction, primary agglomerations, prospective growth points. On the basis of the obtained results of IIF modeling, the author's model of administrative and territorial division of Kharkiv region into eight enlarged districts was proposed, given the specific features of the settlement system and the correlation of area and population of the modeled administrative and territorial units. The scientifically grounded division of the region into enlarged districts (counties) and stimulation of their development will contribute to the most complete and rational use of the territories potential, increase of economic, human, investment potential, rise of the level and quality of life of the population, etc.

scholarly journals PRESERVED STATION COMPLEXES OF THE RAIL NETWORK OF THE VOLHYNIAN GOVERNORATE AS OBJECTS OF ARCHITECTURAL HERITAGE

2021 ◽  
pp. 69-79
Author(s):  
Mykola Nazaruk
Keyword(s):  
Spatial Structure ◽  
Research Methods ◽  
Research Methodology ◽  
Research Topic ◽  
Town Planning ◽  
Architectural Heritage ◽  
Railway Station ◽  
Railway Stations ◽  
Rail Network

The relevance of the research topic is determined by the problems connected with preserving the authenticity of the historical environment of Volhynia. Preserved railway stations, as well as buildings that are part of the railway station complexes, that were built in the Volhynian Governorate in the second half of the XIX – early XX centuries, are valuable architectural objects. Many of preserved station complexes have the features of ensemble unity. For some reason, most of these unique buildings do not have official monument status. Therefore, the author proposes to include in the register of architectural monuments those passenger buildings, as well as buildings of station complexes, that are part of the architectural ensemble, that do not have status of monument and about that is written in this article. Some railway station complexes are in decline due to the closure and need immediate measures to preserve them. There are recommendations for the rehabilitation and protection of the preserved of railway station complexes, that were built in the Volhynian Governorate. The research methodology is based on general, interdisciplinary and disciplinary, that include architectural and town-planning research methods. This publication aims to substantiate the architectural value of the buildings of  railway station complexes, that were built in the Volhynian Governorate in the second half of the XIX – early XX centuries and have been preserved to this day. The task is also to substantiate the proposal to include in the register of architectural monuments those passenger buildings that do not have status of monument and about that is written in this article. The article deals with the volume-spatial structure and stylistics of the of the buildings of  railway station complexes, that were built in the Volhynian Governorate in the second half of the XIX – early XX centuries and have been preserved to this day. Considerable attention is paid to the architectural value of these passenger buildings. The author substantiates the proposal to include in the register of architectural monuments those passenger buildings, as well as buildings of station complexes, that are part of the architectural ensemble, that do not have status of monument and about that is written in this article.

scholarly journals Muhammadiyah Non-Formal Education During the Covid 19 Pandemic

2021 ◽  
Vol 10 ◽  
pp. 39-41
Author(s):  
Nur Fazriya Masfufa ◽  
Muhlasin Amrullah
Keyword(s):  
Qualitative Research ◽  
Data Collection ◽  
Research Methods ◽  
Natural Environment ◽  
Formal Education ◽  
Information Sources ◽  
Research Process ◽  
Qualitative Approach ◽  
Practical Education ◽  
Comprehensive Picture

Non-formal education is practical education or training for the community that is still carried out by the community to increase knowledge and increase interest in talent in themselves. The purpose of this study is to find out about Muhammadiyah non-formal education, the goals and benefits of non-formal education, the characteristics of Muhammadiyah non-formal education and forms of non-formal education of Muhammadiyah. The data collection techniques were interviews and observations, interviews with resource persons Mrs. Sumjiana (managers) and observations and research at the Muhammadiyah branch of the Muhammadiyah College in Gedangan District. This study uses descriptive qualitative research methods. A qualitative approach is a research process to understand social or human problems by analyzing words to create a complex and comprehensive picture, as well as reporting detailed information views obtained from information sources in the natural environment. Muhammadiyah non-formal education during the COVID-19 pandemic took various forms. Muhammadiyah non-formal education such as TK Aisyah 1 Gedangan and TPQ Tunas Jasmine in Gedangan District.

scholarly journals First record of the semi-slug Omalonyx unguis (d’Orbigny, 1837) (Gastropoda, Succineidae) in the Misiones Province, Argentina

Check List ◽  
2018 ◽  
Vol 14 (4) ◽  
pp. 705-712
Author(s):  
Leila B. Guzmán ◽  
Enzo N. Serniotti ◽  
Roberto E. Vogler ◽  
Ariel A. Beltramino ◽  
Alejandra Rumi ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Morphological Characteristics ◽  
First Record ◽  
Coi Gene ◽  
Cytochrome Oxidase Subunit ◽  
Specific Identification ◽  
Molluscan Fauna ◽  
Misiones Province ◽  
Species Specific ◽  
Northeastern Argentina

Omalonyx unguis (d’Orbigny, 1837) is a semi-slug inhabiting the Paraná river basin. This species belongs to Succineidae, a family comprising a few representatives in South America. In this work, we provide the first record for the species from Misiones Province, Argentina. Previous records available for Omalonyx in Misiones were identified to the genus level. We examined morphological characteristics of the reproductive system and used DNA sequences from cytochrome oxidase subunit I (COI) gene for species-specific identification. These new distributional data contribute to consolidate the knowledge of the molluscan fauna in northeastern Argentina.

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