Characterization of the patient with chemotherapy-induced oral mucositis / Caracterização do paciente com mucosite oral induzida por quimioterapia / Caracterización de la paciente con mucositis oral inducida por quimioterapia

Objectives: To characterize cancer patients with oral mucositis treated at a private health facility. Methodology: An exploratory study with descriptive quantitative approach developed in 87 patients in a private practice oncology in Teresina, PI, from August 2011 to January 2012. Results: Findings indicated the prevalence of oral mucositis in males and in the age groups 40-59 years and more than 60. The most common cancer diagnoses were gastrointestinal tract and breast cancer, the treatments focused on chemoradiation, determining predominantly grades I and II of oral mucositis. Overall, mucositis had low discontinuation of cancer treatment and nursing procedures were mainly observed when patients had mucositis grade I. Conclusion: Patients are mostly female, age 40-59 years, with an education 11 or more years. Have an income 2-4 minimum wages and the most frequent types of cancers were the gastrointestinal tract and breast cancer, respectively. Descriptors: Stomatitis. Oncology. Chemotherapy. Nursing

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Targeting Engineered Nanoparticles for Breast Cancer Therapy

Pharmaceutics ◽

10.3390/pharmaceutics13111829 ◽

2021 ◽

Vol 13 (11) ◽

pp. 1829

Author(s):

Kumar Ganesan ◽

Yan Wang ◽

Fei Gao ◽

Qingqing Liu ◽

Chen Zhang ◽

...

Keyword(s):

Breast Cancer ◽

Side Effects ◽

Exploratory Study ◽

Engineered Nanoparticles ◽

Therapeutic Effects ◽

Breast Cancer Therapy ◽

Normal Tissues ◽

Therapeutic Drugs ◽

Common Cancer ◽

Important Approach

Breast cancer (BC) is the second most common cancer in women globally after lung cancer. Presently, the most important approach for BC treatment consists of surgery, followed by radiotherapy and chemotherapy. The latter therapeutic methods are often unsuccessful in the treatment of BC because of their various side effects and the damage incurred to healthy tissues and organs. Currently, numerous nanoparticles (NPs) have been identified and synthesized to selectively target BC cells without causing any impairments to the adjacent normal tissues or organs. Based on an exploratory study, this comprehensive review aims to provide information on engineered NPs and their payloads as promising tools in the treatment of BC. Therapeutic drugs or natural bioactive compounds generally incorporate engineered NPs of ideal sizes and shapes to enhance their solubility, circulatory half-life, and biodistribution, while reducing their side effects and immunogenicity. Furthermore, ligands such as peptides, antibodies, and nucleic acids on the surface of NPs precisely target BC cells. Studies on the synthesis of engineered NPs and their impact on BC were obtained from PubMed, Science Direct, and Google Scholar. This review provides insights on the importance of engineered NPs and their methodology for validation as a next-generation platform with preventive and therapeutic effects against BC.

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“Incidence and Prognosis of Breast Cancer among the Females of Islamabad”

International Journal of Cancer Research & Therapy ◽

10.33140/ijcrt.04.01.2 ◽

2019 ◽

Vol 4 (1) ◽

Keyword(s):

Breast Cancer ◽

Oil And Gas ◽

Medical Center ◽

Age Groups ◽

Life Time ◽

Cross Sectional Study ◽

Oil And Gas Development ◽

Cross Sectional ◽

Common Cancer ◽

Stage 4

Breast cancer is the most common cancer in women worldwide. It is estimated that more than 1.7 million new cases of breast cancer occurred among women worldwide. The disease occurs almost entirely in women, but men can get it, too. For men the life time risk of getting breast cancer is 1 in 1000. A cross sectional study on Breast cancer was carried out in the medical center of Oil and Gas Development Company Islamabad. The purpose of this study was to find out the incidence of breast cancer in different age groups of females and its response to the available treatment in Pakistan. The period of study was from July 2017 to June 2018. Total numbers of 210 females screened were between the ages of 25-65 years; with different complaints related to their breast. 29 females (14%) were found having breast cancer. 10 patients were with stage 4. Five of them were between the ages of 30-40 years, one was 28 years and four patients were between the ages of 41-65 years. Stage 3 patients were 5 (17.2%), two (40%) were between the ages of 30-40 years and three patients (60%) were between the ages of 41-65 years. However stage 2 patients were 13 (44.8%). Among the 13 stage 2 patients seven (54%) were between the ages of 30-40 years and six (46%) were between the ages of 41-65 years.

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