scholarly journals “Incidence and Prognosis of Breast Cancer among the Females of Islamabad”

Breast cancer is the most common cancer in women worldwide. It is estimated that more than 1.7 million new cases of breast cancer occurred among women worldwide. The disease occurs almost entirely in women, but men can get it, too. For men the life time risk of getting breast cancer is 1 in 1000. A cross sectional study on Breast cancer was carried out in the medical center of Oil and Gas Development Company Islamabad. The purpose of this study was to find out the incidence of breast cancer in different age groups of females and its response to the available treatment in Pakistan. The period of study was from July 2017 to June 2018. Total numbers of 210 females screened were between the ages of 25-65 years; with different complaints related to their breast. 29 females (14%) were found having breast cancer. 10 patients were with stage 4. Five of them were between the ages of 30-40 years, one was 28 years and four patients were between the ages of 41-65 years. Stage 3 patients were 5 (17.2%), two (40%) were between the ages of 30-40 years and three patients (60%) were between the ages of 41-65 years. However stage 2 patients were 13 (44.8%). Among the 13 stage 2 patients seven (54%) were between the ages of 30-40 years and six (46%) were between the ages of 41-65 years.

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Johann Paulo S. Guzman ◽  
Leandro L. Resurreccion ◽  
Maria Beatriz P. Gepte

Abstract Background Evaluating blood ordering and subsequent development of a blood ordering schedule can decrease over-ordering of blood among pediatric surgical patients. The objective is to assess our practice of blood utilization using various blood utilization indices and calculate the Maximal Surgical Blood Order Schedule (MSBOS). This is a cross-sectional study for 3 years that included patients (≤ 18 years old) who underwent major surgical procedures in the Philippine Children’s Medical Center. Data included type of surgery, age and sex, number of units crossmatched, number of units transfused, and timing of transfusion. Indices were calculated. Results This study revealed that the utilization rate was only 39.1% of blood among a total of 5314 cases done. The indices were analyzed according to different procedures among different age groups. Procedures for head and neck, colorectal, ostomy, solid tumors, genitourinary abnormalities, upper gastrointestinal, and appendectomy had CT (crossmatched to transfusion) ratio exceeding 2.0, indicating inappropriate blood ordering. Major abdominal, major thoracic, and hepatobiliary surgery all have CT ratio < 2.0. MSBOS was calculated, and a requisition of 1 unit of blood among patients undergoing these procedures is suggested. Conclusions The MSBOS is largely utilized to the adult population but its creation can also be utilized among pediatric patients. Our data shows that in majority of elective pediatric surgical procedures, routine crossmatch is not necessary which is proven by our high underutilization of requested blood products.


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257627
Author(s):  
Pei-Chen Chen ◽  
Pei-Chen Li ◽  
Dah-Ching Ding

Objectives Most research into the management of pelvic inflammatory disease (PID) is in younger women and focuses on sexually transmitted pathogens such as N. gonorrhoeae or C. trachomatis. Non-sexually transmitted bacterial pathogens and PID in older women are rarely examined. The objective of this study is to explore cervical culture pathogens in women of different age groups in a medical center in eastern Taiwan. Methods We enrolled patients whose medical records were diagnosed with PID (ICD-9-CM 614.0 [N70.01–03], 614.1[N70.11–13], 614.9 [N73.5, N73.9]) at our hospital from October 2014 to March 2020. Patients were divided into three groups according to age: the age <25 years, age 25–44 years, and the ≥ 45 years group. Chi-square test, ANOVA and logistic regression were used for statistical analysis. In subgroup analysis, endocervical pathogens were further stratified into vaginal, respiratory, enteric, skin, oral, and other. Results A total of 96 patients were included in the study. There were 31 patients in the age ≥ 45 years group, 52 patients in the age 25–44 years group, and 13 patients in the age <25 years group. Vagina and enteric pathogens were the most common pathogens among all groups. The isolated respiratory and other pathogens were more in the age ≥ 45 years group than in the other two groups. Prevotella bivia was more common in the age <25 years and 25–44 years groups. Conclusions This may be due to different pathogeneses of PID in the age ≥ 45 years patients. Our study can be used as a reference for antibiotic choice of non-sexually transmitted PID and to prevent long-term sequelae of PID.


Background and Aim: The Breast cancer is very common. These patients develop sexual dysfunction following chemotherapy. The aim of this study was to evaluate the effect of chemotherapy in breast cancer patients on their sexual function. Materials and Methods: This descriptive-analytical cross-sectional study was performed on patients with breast cancer referred to Iran-Mehr Medical Center in winter 2018 undergoing chemotherapy. 119 patients were enrolled in the study under census. The Rosen’s Sexual Function Questionnaire was used to collect data. Data were analyzed by using SPSS (Version 16) and Smirnov-Kolmogorov, Kruskal-Wallis and Mann-Whitney tests at the significant level of (P<0.05). Results: In terms of sexual function, the lowest score was 2.40 and the highest score was 14.90. In the study of sexual function components, patients were in the worst condition in terms of pain, 0.84±0.75 and humidity 0.85±0.73. The mean scores of other components included orgasm 1.13±0.64, irritability 1.05±0.84, satisfaction 1.23±0.30 and sexual desire 1.66±0.66, respectively. The only factor affecting sexual function Location, age of marriage and age of patients. Conclusion: The score of sexual function was less than the minimum; the most disorders were recorded for the components of pain and humidity. Factors affecting sexual function were included: location, years of menopause, type of treatment, age of patients and years of marriage. It is recommended that the sexual status of breast cancer patients be evaluated before and during treatment and that the necessary training be provided to inform patients about this disorder and the necessary treatments to improve sexual function.


2020 ◽  
Vol 10 (4) ◽  
pp. 397-401
Author(s):  
Shayma Hamed ◽  
Ayad CE ◽  
Rana Eisa ◽  
Awadia Gareeballah ◽  
Alaa Ibrahim ◽  
...  

Background: Assessment of the pituitary gland (PG) measurements is essential for the diagnosis of many pathological conditions. For Sudanese adult females, however, there have been no studies and no reference values for PG measurements. Therefore, the aim of this study was to determine the regular dimensions of the PG, using MRI, and to correlate these measurements with age, the shape of sella turcica, puberty age, and parity in Sudanese females. Methods and Results: This cross-sectional study was done to assess the PG measurement in Sudanese adult females (n=63) aged between 20 years and 60 years who underwent a brain MRI examination between 2015 and 2019. The study was conducted at Yastabshiroon Umodorman Medical Center (Khartoum, Sudan). The MRI brain examination found that the mean length, depth, width, and volume of the PG were 10.57±1.27 mm, 5.56±1.42 mm, 12.18±1.67 mm, and 356.38±100.22 mm3, respectively. Concerning the shape of the sella turcica, the study revealed that the convex and concave shape were more frequent than others (39.7% and 34.9%, respectively). The depth, width, length, and volume of the gland had changed significantly with pituitary shapes. The PG depth was significantly higher in nulliparous females than multiparous ones. Conclusion: The PG measurement in adult Sudanese females decreased in the sagittal depth and volume gradually till the age of 50 years then returned to increasing after age 50. Younger females in the age group of 20-30 years had a larger depth and volume of the gland than other age groups.


2021 ◽  
Vol 8 (4) ◽  
pp. 691-703
Author(s):  
Yanyan Li ◽  
◽  
Hong Liu ◽  
Yaoyao Sun ◽  
Jie Li ◽  
...  

<abstract><sec> <title>Purpose</title> <p>To identify the characteristics and subtypes of depressive symptoms and explore the relationship between depressive subtypes and age among Chinese female breast cancer patients.</p> </sec><sec> <title>Method</title> <p>In this cross-sectional study, 566 breast cancer patients were recruited from three tertiary comprehensive hospital in Shandong Province, China through convenient sampling from April 2013 to June 2019. Depressive symptoms were measured using the Patient Health Questionnaire-9 (PHQ-9). Data analyses included descriptive analyses, latent class analysis.</p> </sec><sec> <title>Results</title> <p>There were significant differences in specific depressive symptoms by age group, but no significant difference in total scores on PHQ-9. The depressive subtypes were severe (Class 4), relatively severe (Class 3; with lower psychomotor agitation/retardation and suicidal ideation), moderate (Class 2; with higher psychomotor agitation/retardation and suicidal ideation), and mild depressive symptoms (Class 1). The distribution of depression subtypes is different in various age groups. In the 45–59 age groups, severe symptoms subtype showed the highest ratios (i.e. 50.3%).</p> </sec><sec> <title>Conclusion</title> <p>This is the first study that analyses depressive symptom characteristics and identifies depressive subtypes in Chinese women with breast cancer across ages to explore symptom heterogeneity. Our findings can contribute to identifying the mechanisms behind these relationships and developing targeted interventions for patients with specific depressive subtypes.</p> </sec></abstract>


2021 ◽  
Vol 8 (21) ◽  
pp. 1696-1700
Author(s):  
Suma Madathiveetil ◽  
Jisha Kalathil Thodiyil ◽  
Freena Rose

BACKGROUND Breast cancer is now the most common cancer in cities in India and 2 nd most common cancer in the rural areas. Fine needle aspiration cytology (FNAC) is a less invasive pre-operative diagnostic method and is preferred over core / excision biopsy to decide the benign or malignant nature of the breast lump. Prognostic factor assessment by FNAC would allow the identification of patients who would benefit from neo adjuvant treatment (patients with grade 3 tumours) and in whom conservation surgery is inadvisable.1 The purpose of this study is to compare the grades of breast cancer in FNAC with histopathology as gold standard and compare the oestrogen (ER) and progesterone (PR) hormonal expression pattern on immunocytochemistry (ICC) with immunohistochemistry (IHC). From this study we intend to assess the usefulness of cytological grading and ER, PR hormone receptor status pre-operatively so that hormonal therapy can be included with neoadjuvant chemotherapy. METHODS This is a cross sectional study with a sample size of 50, conducted in the Department of Pathology. RESULTS Out of 50 cases, maximum number of patients were in the age group of 51 - 60 years. 68 % had attained menopause; 69 % of patients had tumour size between 2 - 5 cm and 90 % of tumours were in the upper outer quadrant of breast. Considering hormonal expression, in case of ER there was a moderate agreement between ICC and IHC (κ = .428, P = 0.005) and no agreement was seen in case of PR (κ = .073, P = 0.625). Regarding the cytological grading, this study showed highest degree of concordance with grade II tumours with a sensitivity of 75.9 %. For Grade I it was 2.5 % and for grade III, it was 33.3 %. CONCLUSIONS Evaluation of hormonal status and nuclear grading is fairly reliable on cytology when performed on qualitatively superior FNAC material from the primary breast lesions. KEYWORDS Carcinoma Breast, FNAC, ER / PR, Immunocytochemistry, Immunohistochemistry, Cytological Nuclear Grading


2021 ◽  
Vol 5 (4) ◽  
pp. 307-314
Author(s):  
Deepak Sundar Shrestha ◽  
Sajani Manandhar ◽  
Rajendra Rijal ◽  
Corazon A Ngelangel

Introduction: This study evaluates the attitude of physicians regarding cancer the disease and patients with cancer, which may influence their management allowing for recommendations of appropriate interventions.Methods: This is a cross-sectional study, which interviewed 251 physicians of Jose R Reyes Memorial Medical Center regarding their attitudes on cancer and cancer patients. The study also explored and identified factors associated with such attitudes. The validated modified Cancer Attitude Scale of Haley et al (1968, 1977) was used. Ordinal (proportional odds) regression via Stata was used to examine the association between independent and dependent variables. A score of 1 to 5 was given from strongly agree to strongly disagree for all 21 negatively affirmed questions and a score of 1 to 5 was given from strongly disagree to strongly agree for the 11 positively affirmed questions. The cut off levels to say positive or negative attitude was set as a median score of above 3 for each question representing positive attitude and score of below 3 representing negative attitude.Results: In general the overall attitude of physicians working in Jose R Reyes Memorial Medical Center towards cancer and cancer patients is positive. However the physicians are skeptical of the patient’s inner resource to cope with cancer. Expertise, years of practice (of more than 25 years), having experience with cancer patients, being active in religion, Filipino nationality and protecting oneself from carcinogens showed to be associated with positive attitude. Conclusion: The factors that affect physicians’ attitude towards cancer and cancer patients should be further explored with a larger and more representative population of physicians for a wider view of attitudes across age groups, clinical experience, religion, medical specialty among others; so that appropriate interventions may be devised to determine ways that can positively impact their perception. Hence, improving patient management. 


2018 ◽  
Vol 10 (4) ◽  
pp. 114
Author(s):  
Zena Habeeb Yousif ◽  
Selwa Elias Yacoub

BACKGROUND & OBJECTIVES: Breast diseases in women, whether benign or malignant, are very commonly encountered. The pattern of breast diseases varies within countries. The aim of this study was to identify the patterns of breast diseases and their association with different variables in women attending breast diseases diagnosing center in Erbil city/Iraq.MATERIAL & METHODS: A cross-sectional study conducted at breast diseases diagnosing center in Erbil city from 1st of April till 1st of December /2017. A random sample of 500 women of all age groups and with complete records was recruited. The women were classified according to their final diagnosis into 3 categories: normal, benign and malignant breast disease. The level of significance was <0.05.RESULTS: Benign breast diseases diagnosed among (63%) women while malignant breast diseases comprised (13.2%).The most common presentation was mastalgia and mass (39.2%), mastalgia (37.6%), and mass alone (23.2%). Fibro-adenoma (26.2%) was the commonest benign condition with highest incidence (76.9%) in age group less than 20 years. Malignant breast diseases were increasing with age. Benign breast disease associated (p <0.001) with Nulliparity. Breast cancer reported (p <0.001) more among lactating women.CONCLUSIONS: Benign conditions are the most common diagnosis affecting mainly younger women. Breast cancer though diagnosed less frequently and affecting older age groups, yet its seriousness mandating a thorough assessment of women of different presentations especially that of mass alone or with mastalgia.


Author(s):  
Sushma Katkuri ◽  
Misha Gorantla

Background: Breast cancer is the second most common cancer overall and is the most common cancer in women worldwide, both in the developed and developing countries. There are about 1.38 million new cases and 458,000 deaths from breast cancer each year. The aims and objectives of the study were to determine the awareness about breast cancer among urban slum women.Methods: A community based cross–sectional study was conducted at urban slum Shahpur Nagar, Hyderabad. The study participants were above 15 years of age and the study was conducted for a period of one month. A total of 200 study participants were enrolled.Results: Only 35% of the study population was aware about the early danger signs and 66% were unaware. Those who were aware in that 46.3% were breast lump is the early warning sign of breast cancer, followed by 28% said breast abscess, 16% pain in breast, 9% painless lump and 1.4% said for nipple discharge. Regarding skin changes nobody was aware about it. Awareness about risk factors for breast cancer was very poor that is only 21% were knowing about the risk factors about breast cancer. Near about 54% said they are aware about breast cancer by clinical examination done by doctor, 35% said by self breast examination and 12% said by mammography.Conclusions: Intensified health education campaigns should be conducted in the community and they be made aware about breast cancer. 


Author(s):  
Sri Burhani Putri

Breast cancer is one of the most common illness that killed woman. One of the therapy to cure breast cancer is chemotherapy. Chemotherapy has side effect either physical and psychology, that caused people who’s in chemo therapy, prone to stress. Stress effected by many factors, such as characteristic and chopping strategy that patient has been using. The aim of this research is to get a perspective about the relation of characteristic and chopping strategy with breast cancer patient stress, whose in chemo therapy. This research using cross sectional study and taking sample by using accidental sampling method. The data analyzed by using bavariat and multivariat with variable result shows that breast cancer patient stress who has chemo therapy realted to age characteristic (p value = 0.00) the time since they diagnosed with cancer (pvalue = 0.03), how long they have chemo therapy (pvalue = 0.00) and chopping strategyby looking social support (pvalue = 0.00) looking for spiritual (pvalue = 0.00) with dominan variable which related to stress is chopping strategy to looking spiritual support (coeffecients B = -1.139).   Key words : Breast cancer, chemotherapy, stress  


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