scholarly journals Initiative Study for High Cholesterol Inhibitor with Various Components from Natural Herb Medicine

Author(s):  
Tai Jin Kim
2020 ◽  
Vol 10 (6) ◽  
pp. 7061-7069

Lansau is a traditional herb medicine from Muna ethnic, Southeast Sulawesi, Indonesia, consisting of 44 medicinal plants. This study was performed to determine and evaluate the antihyperlipidemic effect of ethanol extract of Lansau in high cholesterol and propylthiouracil induced hyperlipidemic rats. The animal test Wistar strain were used and divided into six groups namely KN (Na. CMC 1%), K (-) (Na CMC 1% + MDLT), K (+) (simvastatin 0.40 mg/kg BW), LS I (Lansau ethanol extract 6.907 mg/kg BW), LS II (ethanol extract Lansau 13.814 mg/kg BW) and LS III (Lansau LS III ethanol extract 27.628 mg/kg BW. The results showed that ethanol extract of traditional Lansau medicine with dose LS I 6.907 mg/kg BW, LS II 27.628 mg/kg BW and LS III 27.628 mg/kg BW have significant activity as antihyperlipidemic (cholesterol and triglyceride) compared to negative control groups (p <0.05) and showed the same activity with simvastatin in lowering total cholesterol and triglyceride levels (p> 0.05), which shows its potential as antihyperlipidemic herbal medicine.


2021 ◽  
Vol 17 ◽  
Author(s):  
Mayank Kulshreshtha

: An increase in the level of cholesterol day by day is easily seen in most people just because of poor life style, food with high cholesterol, lack of physical work, etc. There are lots of molecules available, which lower down the cholesterol level. In this field a new molecule has been introduced that is bimpedoic acid. Researches indicate that bempedoic acid has the same mechanism of action as statins, which means that it also inhibits the HMG-CoA reductase enzyme. This letter to the editor is my best collection of published scientific data on bempedoic acid till now. It also includes the chemistry, pharmacodynamic and pharmacokinetic parameters of the mentioned new molecule.


Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
MA Lacaille-Dubois ◽  
A Chenni ◽  
DA Yahia ◽  
FO Boukortt ◽  
J Prost ◽  
...  

Diabetes ◽  
1980 ◽  
Vol 29 (10) ◽  
pp. 774-777 ◽  
Author(s):  
C. M. Arbeeny ◽  
D. Edelstein ◽  
S. R. Freedman ◽  
H. A. Eder

Author(s):  
R.А. Idrisov ◽  

The correct construction of agrophytocenoses on the slopes of the steppe trans-Urals helped to create maximum productivity. In the arid climate, the most productive were the double mixtures of alfalfa with brittle sitnik, wheatgrass is syd, providing an average of 41.6 and 40.2 quintals per hectare (c/ha) of hay, 32.1 and 31.0 GJ/ha OE (exchange energy per hectare), 4.5 and 4.3 quintals per hectare of boiled protein (c/ha) over 5 years. Single-species steppe ecotypes, brittle sieve and wheatgrass sieve in productivity slightly gave way to double components, providing respectively hay- 32.2 and 37.2 cents per hectare, exchange energy 22.2 and 25.7 GJ/ha, digested protein 1.93 and 2.53 c/ha. The enrichment of agrophytocense by the legume component allowed to increase the metabolic energy content to the level of 32.1 and 31.0-GJ/ha, digested protein to 4.5 and 4.3 quintals per hectare, which is 14 times the nutritional value of the metabolic energy, the digested protein is 10 times higher than the natural herb.


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