EFFECT OF THE DRUG “MELAPOL” ON THE GROWTH OF YOUNG DAIRY GOATS

Author(s):  
N.I. VLADIMIROV ◽  
Keyword(s):  

Changes in the live weight of goats aged from 3 to 6 months are analyzed. with the introduction of the drug “Melapol”, which contains melatonin-the hormone of the pineal gland.

Author(s):  
V.S. ZOTEEV ◽  

Changes in the live weight of goats aged from 3 to 6 months are analyzed. with the introduction of the drug “Melapol”, which contains melatonin-the hormone of the pineal gland.


Biology ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 311
Author(s):  
Francisco G. Véliz-Deras ◽  
César A. Meza-Herrera ◽  
Miguel Mellado ◽  
Viridiana Contreras-Villarreal ◽  
Leticia R. Gaytán-Alemán ◽  
...  

Seasonal reproduction restricts the offering of goat commodities across the year. Therefore, it is crucial to improve diverse strategies to induce the reproductive response in goats during the anestrus stage. The effectiveness of a short P4 + eCG-based estrus induction protocol during both the deep anestrous (March) or the reproductive transition period (June) upon the reproductive performance of crossbred dairy goats was assessed. Adult, anestrous, 24–30-month- old dairy crossbred (Saanen–Alpine–Nubian × Criollo) goats (n = 123) from two commercial herds and 10 sexually active goat bucks were used. Before the trials, the anestrous status of goats was confirmed. Then, goats were randomly allocated into two different experiments. In Exp. 1, we tested the effect of different doses (D) of intramuscular progesterone (P4; 10 or 20 mg + eCG (100 UI)) and type of breeding (TB), natural mating (NM), or artificial insemination (AI), on two commercial goat herds (H1 & H2), in March (deep anestrous). In Exp. 2, we evaluated the effect of D (P4; 10 or 20 mg + 100 UI eCG) in goats subjected to NM, and either during deep anestrous (March; M) or transitional anestrous (June; J), in two commercial herds. After breeding, conception and pregnancy were diagnosed with ultrasound scanning. The response variables were estrus induction (EI; %), estrus latency (EL; h), ovulation (OVP; %), ovulation rate (OR; units), fertility (FERT; %), and pregnancy (PREG; %). No differences (p > 0.05) in live weight (LW) and body condition score (BCS) occurred between herds in both trials. In Exp. 1, EI, EL, OVP, OR, FERT, and PREG were affected (p < 0.05) by the H–TB–D interaction, whereas in H1 + P4–20 combination had the highest (p < 0.05) EI, EL, and OVP values. Irrespective of TB, H1 had the largest (p < 0.05) OR, independently of TB or D. Also, the lowest (p < 0.05) OVP occurred in the AI + P4–10 group, while the AI had the lowest (p < 0.05) FERT, irrespective of D. FERT and PREG were two-fold higher (p < 0.05) in NM compared with AI. In Exp. 2, EI, EL, OVP, OR, FERT, and PREG were affected (p < 0.05) by the H–M–D interaction. In general, H2 + P4–10 had the lowest (p < 0.05) reproductive outcomes in March, whereas H1 had the largest (p < 0.05) values in either month. No differences (p > 0.05) between P4 doses occurred for EI, OVP, OR, FERT, and PREG. Yet, the largest (p < 0.05) EL occurred with P4–20 in June. No correlations (p > 0.05) occurred between LW and all the reproductive variables. BCS was positively correlated (p < 0.05) with EI (0.34), OVP (0.44), OR (0.58), and PREG (0.20). Also, positive correlations (p < 0.05) occurred between EI with EL (0.83), OVP (0.80), OR (0.64), and PREG (0.56); EL with OVP (0.58), OR (0.44), and PREG (0.42); OVP with OR (0.79) and PREG (0.70), as well as OR and PREG (0.63). Results of these studies confirm a multidimensional response regarding the effectiveness of P4 + eCG for estrus induction in goats mainly modulated by a specific time within the anestrous season, or even by specific management or a particular environment at the herd level (H1), although quite remarkably independent of the animal’s LW or BCS at herd level. Moreover, the best reproductive outcomes occurred with NM in June. The most reproductive variables were similar using either 10 or 20 mg P4 + 100 IU eCG, giving the possibility to lessen the scale in the use of exogenous hormones while obtaining acceptable out of season reproductive response.


2000 ◽  
Vol 71 (2) ◽  
pp. 359-368 ◽  
Author(s):  
J. A. Abijaoudé ◽  
P. Morand-Fehr ◽  
J. Tessier ◽  
P. Schmidely ◽  
D. Sauvant

AbstractIn a 12-week trial, 12 Alpine and 12 Saanen dairy goats in mid lactation were housed in individual stalls for behavioural, digestive and metabolic studies. Eight of them were fitted with ruminal cannulae. They were offered ad libitum four complete diets CR, CS, FR and FS (450 g dry matter (DM) per kg) in a 4✕4 Latin-square design. Forage: concentrate ratio was either low (C = 30: 70) or high (F = 55: 45) and starch source either rapidly (R, barley) or slowly (S, maize) degraded in the rumen.Diet preferences were tested. DM intake, chewing activities and performance were determined. Ruminal pH and ammonia-nitrogen (NH3-N) concentrations were measured. Goats were also challenged intravenously with glucose (0·2 g/kg live weight) to assess glucose homeostasis.CR was the most preferred diet. The level of intake differed according to the type of starch (2·2 kg DM per day of CR and FR and 2·0 kg DM per day of CS and FS). FS lowered ruminal pH significantly less than the other diets after the meal. Ruminal NH3-N concentrations were lower in goats given CR and CS than FR and FS. Goats’ resistance to a glucose challenge was not different among diets. Milk yield was 2·00, 1·85, 2·01, 1·85 kg/day on CR, CS, FR and FS respectively. Milk fat content decreased significantly with diets rich in concentrate (24 v. 26 g/kg milk) but milk protein content varied only a little.In conclusion it appears that (1) higher forage: concentrate ratios were less preferred and decreased ruminal acidity but increased daily chewing, ruminal NH3-N and milk fat content; and (2) rapidly degraded starch increased intake, ruminal acidity and milk yield.


Biology ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 354
Author(s):  
Santiago Zuñiga-Garcia ◽  
César A. Meza-Herrera ◽  
Adela Mendoza-Cortina ◽  
Carlos Perez-Marin ◽  
Noé M. Lopez-Flores ◽  
...  

The possible role of the social rank (R) (i.e., low-LSR, middle-MSR, or high-HSR) in anestrus goats exposed to a P4 + eCG (D) (i.e., 100 or 350 IU) estrus induction protocol (EIP) was evaluated. Goats (Alpine-Saanen-Nubian × Criollo; n = 70; 25° North) managed under stall-fed conditions were all ultrasound evaluated to confirm anestrous status, while the social rank was determined 30 d prior to the EIP. The response variables included estrus induction (EI, %), duration of estrus (DUR, h), ovulation rate (OR, n), live weight (LW, kg), thoracic perimeter (TP, cm), thoracic diameter (TD, cm), body length (BL, cm), height at withers (HW, cm), beard length (BEA, cm), compactness index (COM, cm), and anamorphosis index (ANA, cm), as affected by R, D, and the R × D interaction were evaluated, while the correlation coefficients among reproductive and morphometric variables were quantified. An R × D interaction (p < 0.05) affected the response variables EI, DUR, and OR. While the largest (p < 0.05) EI% occurred in the HSR goats, irrespective of eCG (i.e., 100 or 350 IU), both the shortest estrus duration (DUR, h) and the lowest ovulation rate (OR, n) occurred in the LSR + D100 combination, with no differences among HSR and MSR either with D100 or D350. Regarding the LW and morphometric response variables, (i.e., LW, TP, TD, BL, HW, BEA, COM, and ANA) all of them favored either the HSR and MSR groups, with the lowest phenotypic values occurring in the LSR-goats. The EI% was observed to be positively correlated (p < 0.05) with DUR (0.71), LW (0.28), TP (0.31), TD (0.34), BL (0.33), HW (0.35), COM (0.23), and ANA (0.23). While DUR was correlated (p < 0.05) with TP (0.26) and ANA (0.24), OR demonstrated no-correlation (p > 0.05) with any response variable, either reproductive or morphometric. As expected, LW had high correlation coefficients (p < 0.01) with TP (0.86), TD (0.88), BL (0.82), HW (0.75), BEA (0.51), COM (0.97), and ANA (0.75). In general, the morphometric variables as a whole demonstrated important correlation coefficients among them (p < 0.01), ranging from 0.38 up to 0.84. To estimate the importance of the morphometric differences between social rank upon estrus induction, a principal component (PC) analysis was performed based on the correlation matrix derived from the corporal measurements. The PC1 and PC2 explained 70.3% and 17.6% of the morphometric variation, respectively. The PC1 was a measure of the goat size (i.e., small, medium, large) and its association with estrus occurrence was evaluated using a logistic regression model; the bigger the goat, the increased probability of being in estrus, by up to five times compared to small goats. Our results confirm that the higher social ranked, larger goats amalgamated some fundamental factors to be successful: aggressiveness, primacy to food access, augmented live weight, and corporal size; all of these were able to modulate out-of-season reproductive success in crossbred dairy goats subjected to an estrus induction protocol and managed under stall-fed conditions in Northern Mexico.


Author(s):  
J D Sutton ◽  
A Mowlem

In comparison of barley and molassed sugar beet feed (SBF), as the principal energy sources in the concentrates, for milk production by dairy cows, only small differences have been established with diets containing conventional proportions of forage and concentrates. No similar comparison using dairy goats appear to have been made and the purpose of the present study was to compare the effects of these two energy sources on hay intake and milk production by British Saanen goats.Twenty-nine multiparous Saanen goats were allocated to one of two concentrate types one month before kidding. The concentrates were based on barley (B) (690 kg rolled barley, 310 kg soyabean meal/tonne) or molassed SBF (700 kg SBF, 300 kg soyabean meal/tonne) and were pelleted. They were offered at 0.45 kg/day for 4 weeks before kidding, increasing to 1 kg/day by day 15 after kidding. Chopped lucerne hay was offered through Calan gates at 1.5 kg/day before kidding and ad libitum thereafter. The goats consuming the SBF concentrates were given a high-phosphorus mineral supplement. Feed was offered twice dally and refusals were taken once dally. The goats were milked twice daily and samples were taken on two consecutive milkings weekly. Live weight was measured twice weekly.


Author(s):  
I. V. Siianova ◽  
T. V. Kruchinkina

The work was carried out in the Amur region at the Belogorsk poultry farm. In the period from 2015 to 2019, five experiments were carried out taking into account the seasonality. The aim of the study was to identify the influence of the spectral composition of light sources on the pubertation of replacement young egg chickens at the age of 15 weeks: the development of the pineal gland, pituitary gland and genital organs of the youngs. The study on replacement young egg crosses of Hisex White and Decalb White chickens was carried out. In the breeding workshop, four groups of day-old chickens were formed, 200 heads each. From one day of age to 15 weeks, young birds were kept under light of different colors in conditions of gradually decreasing daylight hours from 24 to 12 hours a day and an illumination level from 50-30 to 7-6 lux. White, yellow, green and blue compact fluorescent lamps were used as light sources. In young birds at the age of 30, 60 and 90 days, the live weight was determined by weighing 100 heads from each group. A 15-week-old bird was bled for β-estradiol content at a random selection of 30 birds from each group. For anatomical examination, 5 pullets from each group were sacrificed at the age of 15 weeks, taking into account the body weight required by the norm. The absolute mass of the pineal gland, pituitary gland, ovary, oviduct was determined in the bird, the length of the oviduct was measured. Regardless of the season of the year, the live weight of 90-day-old young in groups under white and yellow illumination had the upper values of the norm, with green and blue it could be at its lower border. Under white and yellow illumination, pullets at 15 weeks of age have higher serum β-estradiol levels. At anatomical examination in 15-week-old chickens under white and yellow lamps, the absolute mass of the pineal gland is less by 10.5 - 41.7% than under green and blue ones, and the mass of the pituitary gland, on the contrary, is more by 4.8 - 8.3%. Pullets with different color illumination did not have significant differences in the mass of the ovary and oviduct, as well as the length of the oviduct, the level of development of which corresponded to a given age. Under white and yellow lighting, the first signs of the onset of puberty at 15 weeks of age are slightly more pronounced than under green and blue light sources.


2019 ◽  
Vol 42 ◽  
pp. e46084
Author(s):  
João Paulo de Farias Ramos ◽  
Wandrick Hauss de Sousa ◽  
Juliana Silva Oliveira ◽  
Edgard Cavalcanti Pimenta Filho ◽  
Edson Mauro Santos ◽  
...  

The objective of this study was to evaluate the use of sorghum silage, Buffel grass hay and forage palm fodder in the diet of dairy goats by means of performance tests and economic viability of different roughage sources. Eight Anglo-Nubian goats, multiparous, weighing around 40.13 ± 2.76 kg of live weight were used. The experiment lasted 84 days, consisting of four periods of 21 days, distributed in two Latin squares (4x4). The treatments represented by diets with different volumetric sources: SSCF: (sorghum silage+ forage palm+ concentrate); BHCF: (Buffel grass hay + cactus forage+ concentrate); SS: (sorghum silage+ concentrate) and BH: (Buffel grass hay + concentrate). Nutritional intake, digestibility, feed behavior, milk production and chemical composition and economic analysis were evaluated. Animals fed the BHCF diet had higher nutrient intakes and consequently were more productive in fat, protein, lactose, fat free solids and total solids. The BHCF diet led to a higher gross income in Brazilian currency. The safety margin of the SSCF diet presented the highest percentage, with 43.06%, and the BHCF diet, the lowest percentage, of 14.89. The association of forage palm with sorghum silage and Buffel grass hay can be used as a bulky source in lactating goat diets.


2016 ◽  
Vol 83 (2) ◽  
pp. 148-150
Author(s):  
Erick Alonso-Mélendez ◽  
Germán D. Mendoza ◽  
Francisco A. Castrejón-Pineda ◽  
Andrés E. Ducoing-Watty

The objective of the study reported in this Research Communication was to evaluate graded levels of ruminally protected methionine (RPM) in dairy goat rations on milk production and live weight changes during 155 d of lactation. Twenty-five primiparous dairy goats (crosses of Toggenburg, French Alpine and Saanen; 45·4 ± 1·0 kg BW) were fed a basal diet (10·10% CP, 6·13 DP and 2·34 Mcal/kg ME) of corn silage, oat hay, alfalfa hay and concentrate (80% forage, 20% concentrate). After kidding, the treatments, which consisted of four oral doses of ruminally protected methionine (RPM) at 0, 1, 2 and 3 g/d, were randomly assigned to the goats. The experiment was conducted for 110 d with measurements of milk production and composition, body weight and dry matter intake. No treatment effects were detected in milk production and composition. However, goats with RPM showed a positive live weight changes during lactation which were improved as dose was increased (linear P < 0·01) whereas goats without RPM showed weight loss during the experiment.


2021 ◽  
Vol 4 (1) ◽  
pp. 99-114
Author(s):  
Janaína B Garcia ◽  
Fernanda G Do Amaral ◽  
Daniela C Buonfiglio ◽  
Rafaela FA Vendrame ◽  
Patrícia L Alves ◽  
...  

The pineal gland synthesizes melatonin exclusively at night, which gives melatonin the characteristic of a temporal synchronizer of the physiological systems. Melatonin is a regulator of insulin activities centrally and also peripherally and its synthesis is reduced in diabetes.  Since monosodium glutamate (MSG) is often used to induce the type 2 diabetic and metabolic syndrome in animal models, the purpose of this work is to evaluate the potential effects of MSG given to neonates on the pineal melatonin synthesis in different aged male and female rats. Wistar rats were subcutaneously injected with MSG (4mg/g/day) or saline solution (0.9%) from the second to eighth post-natal day. The circadian profiles both melatonin levels and AANAT activity were monitored at different ages. Body weight, naso-anal length, adipose tissues weight, GTT, ITT and serum insulin levels were also evaluated. Typical obesity with the neonatal MSG treatment was observed, indicated by a great increase in adipose depots without a concurrent increase in body weight. MSG treatment did not cause hyperglycemia or glucose intolerance, but induced insulin resistance. An increase of melatonin synthesis at ZT 15 with phase advance was observed in in some animals. The AANAT activity was positively parallel to the melatonin circadian profile. It seems that MSG causes hypothalamic obesity which may increase AANAT activity and melatonin production in pineal gland. These effects were not temporally correlated with insulin resistance and hyperinsulinemia indicating the hypothalamic lesions, particularly in arcuate nucleus induced by MSG in early age, as the principal cause of the increase in melatonin production.


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