scholarly journals Blood profile of obese and aged dogs (Canis familiaris)

2019 ◽  
Vol 88 (1) ◽  
pp. 33-41
Author(s):  
Christina Resende Martins ◽  
Pablo Gomes Noleto ◽  
Renata Lima de Miranda ◽  
Antonio Vicente Mundim

The aim of this study was to evaluate the blood profile and haematological changes in obese adult and senior dogs. An evaluation was made from the blood profile of 59 obese adult and senior dogs. The animals were divided into two groups, group 1 (G1) with 30 obese adult dogs (2 to 8 years) and group 2 (G2) with 29 obese senior dogs (over 8 years old). The mean values of the erythrogram and platelet count parameters of both groups remained within the compared reference ranges except the red cell distribution width (RDW), whose values were lower than the reference ranges in both groups. A comparison of the values of erythrogram and platelet count of the groups indicated that the RDW and MPV (mean platelet volume) of G2 were higher than those of G1. As for the white blood cell count (WBC), only the number of band neutrophils exceeded the physiological limits for the species in both groups, with no significant difference in values between the age groups. The males in G2 showed a significantly higher mean eosinophil count than those in G1 and than the females of both groups. As for the frequency of findings, 90% of the animals in G1 and 68.96% in G2 showed left shift neutrophils (LSN), while 34.48% in G1 and 20% in G2 showed eosinophilia. It was concluded that, irrespective of age, obese animals presented no changes in erythrogram and platelet indices, and that their WBC may exhibit discrete LSN without leukocytosis.

2021 ◽  
Author(s):  
Xianghui Dong ◽  
ZhanKui Jin ◽  
ZhengMing Sun ◽  
Jing Chen ◽  
YanHai Chang ◽  
...  

Abstract Objective We aimed to investigate differences in and trends of normal calcaneal angles among Han Chinese adults from different age groups to establish normal reference ranges of calcaneal angles in these age groups, thereby providing a theoretical basis and morphological reference for the treatment of calcaneal fractures. Methods We collected lateral plain radiographs (X-ray) of the normal ankle joints of 6,260 Han Chinese adults who visited the Radiology Department of Shaanxi Provincial People’s Hospital between November 2008 and December 2020 to measure the calcaneal angles, including the Böhler angle (BA), Gissane angle (GA), calcaneal pitch angle (CPA), posterior facet inclination angle (PFIA), and calcaneal-tibial angle (CTA). On this basis, we analyzed the calcaneal angles in different age groups to summarize the characteristics of normal calcaneal angles in Han Chinese adults. Results According to the lateral plain radiographs of the normal ankle joints of 6,260 (male: 3,380; female: 2,880) adults (mean age: 46.3 ± 18.2 ), the mean values of the BA, GA, CPA, PFIA, and CTA were 33.17° ± 6.08°, 114.99° ± 8.17°, 25.67° ± 4.72°, 64.35° ± 8.51°, and 91.59° ± 11.57°, respectively. Results of the Pearson correlation analysis suggested negative correlations between age and both BA and PFIA (P < 0.01, respectively) but a lack of correlation between age and the GA, CPA or CTA (P > 0.05, respectively). One-way analysis of variance (ANOVA) and the least significant difference (LSD) test showed that at above the age of 18, there were statistically significant differences both in the BA between different age groups and in the PFIA between different age groups above 41 years old. Conclusion In Han Chinese adults, there are significant differences in BA and PFIA between different age groups, with these calcaneal angles exhibiting a trend of decrease with age.


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Tolga Yilmaz ◽  
Ahu Yilmaz

Purpose. To investigate whether platelet morphology or function is altered in patients with diabetic retinopathy (DR).Methods. This prospective study enrolled 85 healthy controls (HCs) (group 1) and 262 patients with Type 2 diabetes mellitus (T2DM). Patients were subclassified into three groups according to ocular findings: no DR (group 2;n=88); nonproliferative DR (group 3;n=88), and proliferative DR (group 4;n=86). Mean platelet volume (MPV), platelet distribution width (PDW), platelet large cell ratio (PLCR), plateletcrit (PCT) values, and platelet count were measured in the studied groups.Results. MPV, PDW, and PLCR levels were significantly altered in groups 2–4 compared with HCs (p<0.05,p<0.05,p<0.05). Compared with group 2, both DR groups had higher MPV and PDW levels, with a significant difference between groups 2 and 4 for both MPV (p=0.036) and PDW (p=0.006). PLCR correlated with retinopathy stage, but no significant difference was found between the DR groups. Platelet count and PCT values were not significantly different between the groups (p>0.05).Conclusion. Our findings suggest an association between mean platelet indices (MPI) (i.e., MPV, PDW, and PLCR) and DR stage. Therefore, MPI could be a beneficial prognostic marker of DR in patients with T2DM.


2020 ◽  
Author(s):  
Ebru Salmanoglu

Abstract BackgroundIt was aimed to compare three methods for calculation of sacroiliac joint (SIJ) index in different age groups. Cases undergone Tc-99m MDP bone scintigraphy and images were evaluated. Cases don’t have pathologic uptake were performed posterior pelvic images for calculation of SIJ index.Normal cases (n:160) were included.Cases were separated into four age groups, group 1(3-20 years), group 2(21-40 years), group 3(41-60 years), group 4(61 years and older). For the first method,irregular region of interest (ROI) was selected,for the second method rectangular ROI was selected.For the third method, profile peak counts were used. Count of each SIJ was divided count of sacrum to calculate right, left and mean SIJ indices.ResultsThere was no statistically significant difference between mean values of right and left SIJ index for three methods(p>0.05).Means of female were lower than male for right, left and and mean SIJ indices.Lowest mean values of right SIJ index, left SIJ index and mean SIJ index were found in ≥61 age group in both genders.All of three methods were significantly different from each other according to four age groups(p<0.05). First method had quite lower mean value than second and third methods for right SIJ index.A negative statistically significant correlation was found between age and SIJ index for all of three methods(p<0.01). Statistically significant difference was found between three methods for each age gropus based on mean SIJ index(p<0.05).ConclusionsEach nuclear medicine center should establish their own threshold value according to their own data set in normal cases and patients.


2016 ◽  
Vol 36 (8) ◽  
pp. 677-686 ◽  
Author(s):  
Dietrich Pizzigatti ◽  
Daniele S. Gonçalves ◽  
Thays C. Trentin ◽  
Regina K. Takahira ◽  
Ana L.G. Alves ◽  
...  

Abstract: Jugular thrombosis in horses occurs commonly in iatrogenic situations, secondary to endotoxemic clinical condition and disseminated vascular coagulation, potentially leading to death. Thus, hemostatic evaluation becomes necessary and extremely important for monitoring the risks of systemic hypercoagulability and for the efficiency of allopathic and surgical treatment. This paper describes the hemostatic behavior in experimental jugular thrombosis of ten healthy equines, subsequently submitted to two thrombectomy techniques and receiving heparin sodium as anti-rethrombosis therapy. These animals were evaluated for 20 days by thromboelastometry (TEM), platelet count, hematocrit and fibrinogen, at four moments: pre-induction to phlebitis (D0-MPF); three days after thrombophlebitis induction (D3-MFM); 6 days after, - moment of thrombophlebitis - (D9-MT); and 54 (D16) and 126 (D19) hours after thrombectomies (PTM). Thrombectomy was performed via a Vollmar Ring (group 1, n=5) and Fogarty catheter (group 2, n=5). All the animals received heparin (150 UI/kg, SC) every 12 hours, for ten days after the respective thrombectomies. Through the blood samples were evaluated TEM, activated partial thromboplastin time (aPTT) and prothrombin time (PT), dosing of fibrinogen, hematocrit and platelet count at the abovementioned moments. For comparison between groups and moments the t test was applied at 5% significance level. No significant difference was verified between treatment groups at any of the moments. There were reductions in clotting time (CT) and clot formation time (CFT), with increase in maximum lysis (ML) until the moment D9-MT. Evaluation through INTEM® reagent presented prolongations of CT and CFT with reduction of α angle and ML starting from D16 and D19. Similarly, aPTT presented significant differences between moments pre- (D0, 3 and 9) and post- (D16 and 19) anticoagulant and surgical treatment. The platelet numbers were diminished at moments D16 and D19. In evaluation with EXTEM® reagent, prolongation of CT and CFT occurred only between the moments D0 vs. D3 and vs. D9. O PT did not present significant differences. The results obtained demonstrate that experimental jugular thrombophlebitis leads to local clinical alterations, with impairment of tissue and of the extrinsic coagulation pathway (EXTEM® ), but without evidence of systemic hypercoagulability status, since there was no increase of the alpha angle or maximum clot firmness (MCF). Furthermore, TEM was shown useful and more sensitive than conventional coagulation tests (PT, aPTT and fibrinogen) for the monitoring of anticoagulant therapy, as demonstrated in other works.


2016 ◽  
Vol 10 (02) ◽  
pp. 220-224 ◽  
Author(s):  
Emre Bayram ◽  
Huda Melike Bayram

ABSTRACT Objective: The purpose of this study was to evaluate fracture resistance of teeth with immature apices treated with coronal placement of mineral trioxide aggregate (MTA), bioaggregate (BA), and Biodentine. Materials and Methods: Forty-one freshly extracted, single-rooted human premolar teeth were used for the study. At first, the root length was standardized to 9 mm. The crown-down technique was used for the preparation of the root canals using the rotary ProTaper system (Dentsply Maillefer, Ballaigues, Switzerland) of F3 (30). Peeso reamer no. 6 was stepped out from the apex to simulate an incompletely formed root. The prepared roots were randomly assigned to one control (n = 5) and three experimental (n = 12) groups, as described below. Group 1: White MTA (Angelus, Londrina, Brazil) was prepared as per the manufacturer's instructions and compacted into the root canal using MAP system (Dentsply Maillefer, Ballaigues, Switzerland) and condensed by pluggers (Angelus, Londrina, Brazil). Group 2: The canals were filled with DiaRoot-BA (DiaDent Group International, Canada). Group 3: Biodentine (Septodont, Saint Maur des Fosses, France) solution was mixed with the capsule powder and condensed using pluggers. Instron was used to determine the maximum horizontal load to fracture the tooth, placing the tip 3 mm incisal to the cementoenamel junction. Mean values of the fracture strength were compared by ANOVA followed by a post hoc test. P < 0.05 was considered statistically significant. Results: No significant difference was observed among the MTA, BA, and biodentine experimental groups. Conclusion: All the three materials tested, may be used as effective strengthening agents for immature teeth.


2020 ◽  
Vol 11 (1) ◽  
pp. 42
Author(s):  
Turgay Akalin ◽  
Aysin Sinal

We aimed to reveal psychological symptoms of young university students (18-25 y/o) with no secondary disease with complaints of migraine headaches. We compared the psychological symptoms with a young control group that did not present headaches and other studies examining migraines in different age groups to determine any similarities. The study consisted of 75 migraine cases; 13 with aura and 62 without aura) and 42 non-headache control subjects. The International Classification of Headache Disorders 3 (ICHD-3) with criteria questions and the Psychological Symptom Research Scale were applied to all participants and SPSS Statistics Program evaluated the data. Findings: 1) In the test of Descriptive Statistics for the Sample of Students, average values of both sexes were taken and found the average values of the migraine groups were higher than control group. 2) The Anova Test found differences in the diagnostic group besides depression (Somatisation p<., others p<.01) with no significant difference in depression (p=0.315). 3)The Pearson Correlation Analysis, found no association between age and psychological symptoms. There’s a significant relationship between psychological symptoms with somatisation (besides paranoid) (p<.05). There’s a significant relationship between depression and other psychological symptoms (p<.05). There’s a significant relationship between anxiety, obsession, interpersonal relationships, psychoticism, paranoia, anger, phobia, additional scale and other psychological symptoms (p<.01). Result: The study demonstrated psychological symptoms in young migraineurs. The average psychological symptoms of both migraine groups were higher than the control group, this showed psychological symptom similarities between young migraineurs and migraine patients of different age groups.


2015 ◽  
Vol 31 (1) ◽  
pp. 55-62 ◽  
Author(s):  
O. Stevanovic ◽  
M. Stojiljkovic ◽  
D. Nedic ◽  
D. Radoja ◽  
V. Nikolic ◽  
...  

Karakachan sheep represents an endangered, indigenous sheep breed from Balkan Peninsula. There is relatively little information about the characteristics of this sheep breed in the veterinary scientific literature. The aim of this research was an examination of certain metabolic profile parameters of the Karakachan sheep blood serum, and variability of their concentrations in comparison to age and some other indigenous sheep breeds from Balkans. Examination was conducted on 14 clinically healthy sheep divided in two age groups. Blood samples were collected by puncture of v. jugularis and blood serum was separated after spontaneous coagulation. The concentrations of total protein, albumin, calcium, inorganic phosphorus, aspartate amino transferase (AST) and ?- glutamyl transferase (GGT) were determined. In relation to age of Karakachan sheep, statistically significant difference between the calculated mean values of examined parameters was not observed. A statistically significant difference was found between the mean concentrations of the studied parameters in Karakachan sheep and other breeds in total protein (Tsigai, Dubrovnik and Dalmatian sheep), albumin (Dalmatian), calcium and inorganic phosphorus (Tsigai, Dubrovnik) and AST's (Dalmatian, Karakachan sheep from Bulgaria).


2019 ◽  
Vol 6 (4) ◽  
pp. 1567
Author(s):  
Mahesh B. Maralihalli ◽  
Kavan R. Deshpande ◽  
Pallavi K Deshpande

Background: The objectives of this study was to analyze complete blood counts in rotaviral gastroenteritis with special emphasis on platelet indices.Methods: Children diagnosed as rotavirus gastroenteritis and healthy controls were enrolled in this study. Severity of acute gastroenteritis was classified into mild, moderate and severe grades using Vesikari score. Rotavirus was determined in fresh stool samples using rapid diagnostic rotavirus antigen test. Hemoglobin, leukocyte, neutrophil to lymphocyte percentage ratio, platelet counts, mean platelet volume (MPV), platelet distribution width (PDW) and platelet crit (PCT) levels were assessed for all children. It’s a case control study conducted at Pediatric Speciality Hospital.Results: There were 30 cases with mean age 1.58 years. Healthy controls were 30 with mean age 2.10 years. Mean Hb was lower in cases. Mean of platelet counts was higher in cases. Mean MPV levels was lower in cases. Mean PCT value was higher in cases. Mean MPV to platelet ratio value was lower in cases. All parameters values showed no significant difference among mild, moderate and severe groups of rotaviral gastroenteritis cases. Platelet count was negatively correlated with Hb, MPVP and positively correlated with TLC and PCT. MPV was positively correlated with MPVP and PDW. PCT was negatively correlated with Hb, MPVP and positively correlated with TLC and platelet count.Conclusions: MPV can be used as negative acute phase reactant in rotavirus gastroenteritis and so is the MPV to platelet ratio. Platelet count is acute phase reactant in rotavirus gastroenteritis and so is the platelet crit value.


2020 ◽  
Vol 24 (4) ◽  
pp. 543-548
Author(s):  
M Dikko ◽  
S.O. Bello ◽  
A. Chika ◽  
I.A. Mungadi ◽  
Y. Sarkingobir ◽  
...  

The objective of this paper was to determine the effect of tamsulosin use on plasma insulin status in benign prostatic hyperplasia (BPH) patients in Sokoto, Nigeria. Standard methods and procedures were used. At 2nd and 3rd months of tamsulosin use, there was a significant increase (P<0.05) in plasma insulin values compared to baseline. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was revealed compared to baseline and 2nd month values. Other inter-mean values comparisons were not significantly different (P>0.05). Plasma insulin at 4th months of the study in BPH patients (45-54 years) treated with tamsulosin revealed a significant increase (P<0.05) compared to baseline values. Other inter-mean values comparisons were not significantly different (P>0.05). BPH patients (aged 55-64 years) at 3rd month showed a significant increase (P<0.05) in plasma insulin values compared to baseline values. Likewise, at 4th month of tamsulosin use, a significant increase  (P<0.05) in plasma insulin values was seen compared to baseline and 1st month values. Other inter-mean values comparisons were not significantly different (P>0.05). In BPH patients aged 65 and above, there was no significant difference (P>0.05) in plasma insulin values from 1st through 4th month compared to baseline and other inter mean values comparisons. Plasma insulin at 0th , 1st , 2nd , 3rd and 4th months of BPH patients of different age groups treated with tamsulosin revealed no significant differences (P>0.05). This study revealed that tamsulosin use in the patients lead to significant increase in plasma insulin level (hyperinsulinemia). Careful and routine monitoring of BPH patients should be done. Patients need enough exercise activities and some drugs can be administered to alleviate elevated glucose or insulin. Keywords: Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance


2020 ◽  
Vol 8 (6) ◽  
pp. 232596712092793
Author(s):  
Christopher Antonacci ◽  
Thomas R. Atlee ◽  
Peter N. Chalmers ◽  
Christopher Hadley ◽  
Meghan E. Bishop ◽  
...  

Background: Pitching velocity is one of the most important metrics used to evaluate a baseball pitcher’s effectiveness. The relationship between age and pitching velocity after a lighter ball baseball training program has not been determined. Purpose/Hypothesis: The purpose of this study was to examine the relationship between age and pitching velocity after a lighter ball baseball training program. We hypothesized that pitching velocity would significantly increase in all adolescent age groups after a lighter baseball training program, without a significant difference in magnitude of increase based on age. Study Design: Cohort study; Level of evidence, 2. Methods: Baseball pitchers aged 10 to 17 years who completed a 15-week training program focused on pitching mechanics and velocity improvement were included in this study. Pitchers were split into 3 groups based on age (group 1, 10-12 years; group 2, 13-14 years; group 3, 15-17 years), and each group trained independently. Pitch velocity was assessed at 4 time points (sessions 3, 10, 17, and 25). Mean, maximum, and mean change in pitch velocity between sessions were compared by age group. Results: A total of 32 male baseball pitchers were included in the analysis. Mean/maximum velocity increased in all 3 age groups: 3.4/4.8 mph in group 1, 5.3/5.5 mph in group 2, and 5.3/5.2 mph in group 3. While mean percentage change in pitch velocity increased in all 3 age groups (group 1, 6.5%; group 2, 8.3%; group 3, 7.6%), the magnitude of change was not significantly different among age groups. Program session number had a significant effect on mean and maximum velocity, with higher mean and maximum velocity seen at later sessions in the training program ( P = .018). There was no interaction between age and program session within either mean or maximum velocity ( P = .316 and .572, respectively). Conclusion: Age had no significant effect on the magnitude of increase in maximum or mean baseball pitch velocity during a velocity and mechanics training program in adolescent males.


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