scholarly journals Comparison of Perfectionism and negative affectability in the patients with coronary artery disease and healthy individuals

2020 ◽  
Vol 2 (2) ◽  
pp. 6-14
Author(s):  
Paria Bildari ◽  
Mahmoud fakhe ◽  
Mohammad Azad Abdollahpour ◽  
Narmin Boroumand ◽  
◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Healthy Individuals ◽  
Artery Disease

scholarly journals Serum Myeloperoxidase Levels Are Associated With the Future Risk of Coronary Artery Disease in Apparently Healthy Individuals

2007 ◽  
Vol 50 (2) ◽  
pp. 159-165 ◽  
Author(s):  
Marijn C. Meuwese ◽  
Erik S.G. Stroes ◽  
Stanley L. Hazen ◽  
Joram N. van Miert ◽  
Jan Albert Kuivenhoven ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Healthy Individuals ◽  
The Future ◽  
Future Risk ◽  
Artery Disease ◽  
Apparently Healthy

Adiponectin/C-reactive protein interplay in healthy individuals and in patients with coronary artery disease

2010 ◽  
Vol 144 (1) ◽  
pp. 82-84
Author(s):  
Mahmoud M. Ramadan ◽  
Makoto Kodama ◽  
Masahiro Ito ◽  
Nader El-Shahat ◽  
Mahmoud M. Yousif ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Healthy Individuals ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Artery Disease

scholarly journals A Novel Polymorphism in the Promoter of theCYP4A11Gene Is Associated with Susceptibility to Coronary Artery Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Svetlana Sirotina ◽  
Irina Ponomarenko ◽  
Alexander Kharchenko ◽  
Marina Bykanova ◽  
Anna Bocharova ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Transcription Factors ◽  
Coronary Artery ◽  
In Silico Analysis ◽  
Healthy Individuals ◽  
Epistatic Interactions ◽  
Increased Risk ◽  
Artery Disease ◽  
Silico Analysis ◽  
Age And Sex

Enzymes CYP4A11 and CYP4F2 are involved in biosynthesis of vasoactive 20-hydroxyeicosatetraenoic acid and may contribute to pathogenesis of coronary artery disease (CAD). We investigated whether polymorphisms of theCYP4A11andCYP4F2genes are associated with the risk of CAD in Russian population. DNA samples from 1323 unrelated subjects (637 angiographically confirmed CAD patients and 686 age- and sex-matched healthy individuals) were genotyped for polymorphisms rs3890011, rs9332978, and rs9333029 ofCYP4A11and rs3093098 and rs1558139 ofCYP4F2by using the Mass-ARRAY 4 system. SNPs rs3890011 and rs9332978 ofCYP4A11were associated with increased risk of CAD in women: OR = 1.26, 95% CI: 1.02–1.57,P=0.004, andQ=0.01and OR = 1.45, 95% CI: 1.13–1.87,P=0.004, andQ=0.01, respectively. Haplotype G-C-A ofCYP4A11was associated with increased risk of CAD (adjusted OR = 1.41, 95% CI: 1.12–1.78, andP=0.0036). Epistatic interactions were found between rs9332978 ofCYP4A11and rs1558139 ofCYP4F2(Pinteraction=0.025). In silico analysis allowed identifying that SNP rs9332978 is located at a binding site for multiple transcription factors; many of them are known to regulate the pathways involved in the pathogenesis of CAD. This is the first study in Europeans that reported association between polymorphism rs9332978 ofCYP4A11and susceptibility to coronary artery disease.

Mo-W7:5 Myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals

2006 ◽  
Vol 7 (3) ◽  
pp. 24
Author(s):  
M.C. Meuwese ◽  
S.M. Boekholdt ◽  
J.J.P. Kastelein ◽  
S.L. Hazen ◽  
J.A. Kuivenhoven ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Healthy Individuals ◽  
The Future ◽  
Future Risk ◽  
Artery Disease ◽  
Apparently Healthy

scholarly journals Distinguishing feature of gut microbiota in Tibetan highland coronary artery disease patients and its link with diet

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yulan Ma ◽  
Lulu Zhu ◽  
Zhijun Ma ◽  
Zhongshan Gao ◽  
Yumiao Wei ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gut Microbiota ◽  
Dairy Product ◽  
Tibet Plateau ◽  
Healthy Individuals ◽  
Α Diversity ◽  
Potential Factors ◽  
Artery Disease ◽  
Fermented Dairy

AbstractThe prevalence of coronary artery disease (CAD) in Tibetan Highlanders is lower than that in plain-living individuals, but the mechanism still unclear. Gut microbiota (GM) disorder is considered one of the potential factors involved in the pathogenesis of CAD, but the GM characteristics of Tibetan Highlanders suffering from CAD are unknown. We sequenced the V3-V4 region of the 16S ribosomal RNA of gut bacteria from fecal samples from Tibetan and Han CAD patients and healthy individuals inhabiting the Qinghai-Tibet Plateau, as well as from Han CAD patients and healthy individuals living at sea level, and we analyzed the GM characteristics of these subjects by bioinformatics analysis. The results showed that Tibetan Highlanders suffering from CAD had higher GM α-diversity, with differently distributed cluster compared with healthy Tibetan Highlanders and Han CAD patients living at high and low altitudes. Genera Catenibacterium, Clostridium_sensu_stricto, Holdemanella, and Ruminococcus 2 were enriched in Tibetan Highlanders suffering from CAD compared with healthy Tibetan Highlanders and Han CAD patients living at high- and low-altitudes. Prevotella was enriched in Tibetan Highlanders suffering from CAD compared with Han CAD patients living at high- and low-altitudes. Moreover, Catenibacterium was positively correlated with Prevotella. Additionally, Catenibacterium, Holdemanella, and Prevotella were positively correlated with fermented dairy product, carbohydrate and fiber intake by the subjects, while Clostridium_sensu_stricto was negatively correlated with protein intake by the subjects. In conclusion, our study indicated that Tibetan Highlanders suffering from CAD showed distinct GM, which was linked to their unique dietary characteristics and might associated with CAD.

scholarly journals Non-alcoholic fatty liver disease is associated with subclinical coronary artery disease in otherwise healthy individuals

2021 ◽  
Vol 50 (6) ◽  
pp. 500-502
Author(s):  
Mark Yu Zheng Wong ◽  
Jonathan Jiunn Liang Yap ◽  
Mark Chang Chuen Cheah ◽  
George Boon Bee Goh ◽  
Khung Keong Yeo
Keyword(s):  
Coronary Artery Disease ◽  
Liver Disease ◽  
Coronary Artery ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Healthy Individuals ◽  
Alcoholic Fatty Liver ◽  
Artery Disease ◽  
Alcoholic Fatty Liver Disease

Abstract 1521: Platelet RNA Content is Increased in Patients with Acute Coronary Syndromes Compared to Patients with stable Coronary Artery Disease and Healthy Individuals

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Erik L Grove ◽  
Anne-Mette Hvas ◽  
Steen D Kristensen
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Acute Coronary Syndromes ◽  
Thrombus Formation ◽  
Stable Coronary Artery Disease ◽  
Healthy Individuals ◽  
Coronary Thrombus ◽  
Coronary Syndromes ◽  
Immature Platelets ◽  
Artery Disease

Background: Platelets newly released from the bone marrow are characterized by large cell volumes and, contrary to mature platelets, contain RNA, which might reflect an increased capacity of producing proaggregatory proteins. We hypothesized that the fraction of RNA-containing, immature platelets (Immature Platelet Fraction = IPF) is a marker for acute coronary thrombus formation. Methods: Flow cytometric determination of immature platelets was conducted using a RNA fluorescent dye and an automated analyzer (Sysmex XE-2100). Measurements were performed in a total of 426 individuals (365 patients with acute coronary syndromes (ACS), 39 patients with stable coronary artery disease (CAD) and 22 healthy individuals). Results: Geometric mean IPF was 2.5 (CV = 0.37) in the control group, 2.9 (0.43) in patients with stable CAD, 3.0 (0.55) in the non-STEMI/Unstable Angina group and 3.7 (0.56) in patients with STEMI. IPF was significantly increased in STEMI patients compared to all other groups (t-test for log-transformed data: p < 0.004), and the overall difference between groups was significant (ANOVA: p < 0.0001). IPF was increased in active smokers among patients with ACS (3.2 vs 3.6, p=0.02), whereas no relation with age, sex, body mass index or CRP levels was observed. Conclusion: The fraction of RNA-containing platelets is increased in ACS, especially in the acute phase of STEMI. Immature platelets with an increased haemostatic potential may contribute to coronary thrombus formation and may partly explain previous findings of temporary resistance to anti-platelet therapy.

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