scholarly journals COLORECTAL CARCINOMA

2013 ◽  
Vol 20 (06) ◽  
pp. 1014-1018
Author(s):  
HAMAD RANA ◽  
SHAHID MAHMOOD ◽  
SOSAN SHAHID ◽  
Muhammad Munir ◽  
Mulazam Hussain Bukhari

Introduction: Prognosis is excellent in colonic carcinoma in case of well differentiated growth. All efforts must be done todiagnose the malignancy at an earlier stage for a better outcome specially if it is well differentiated growth. Objectives: To compare thedifferent modes of presentation of carcinoma of large bowel in a tertiary care hospital and their association with pathological findings.Material & Methods: It is a cross sectional retrospective study. Patients with histological proof of carcinoma were included in the study.Data over the period of two year was collected and analyzed. Results: This study included one hundred patients. Mean age was 49.56years and 56 % of the patients were males. 40 % of the patients present between the ages of 40 to 60 years. Mean time of start ofsymptoms and the time of presentation in the hospital was 6.5 months ranges from 1 to 24 months. 76 % of the patients had history ofaltered bowel habits and 60% had anorexia and weight loss. 41.66% of patients had well differentiated growth while 37.55% of patientshad moderately differentiated adenocarcinoma. Conclusions: Majority of the patients with colonic carcinoma had well or moderatelydifferentiated growth. If they are diagnosed and properly treated at an early stage, outcome is good.

2020 ◽  
Vol 11 (SPL2) ◽  
pp. 308-313
Author(s):  
Siddharth A R ◽  
Shiny Chrism Queen Nesan G ◽  
Timsi Jain

A selfie is a self-portrait photograph typically taken with a camera phone held in hand or supported by a selfie stick. Studies suggest that the level of selfie addiction among youngsters has been increasing over the years. is the term that is being widely used to denote selfie addiction. This study aims at assessing the level of selfie addiction and various factors associated with it, and to evaluate the relationship between selfie addiction and addictive selfie habits. A cross-sectional study was conducted among the Allied Health Science students of a tertiary care hospital in Chennai. Two hundred seventy-three students were studied by convenient sampling method. A , validated, structured and self-administered questionnaire was given, and the desired information was elicited. Chi-square test was used to test the significance (p <0.05)A total of 287 students were studied, of which 65 (22.6%) were males, and 222 (77.4%) were females. It is observed that age, year of study, the place from which they come, place of stay and father's occupation have a statistically significant relationship with selfie addiction. Most of the selfie addictive have a female preponderance. A significant portion of the youth is in the early stage of selfie addiction. it is highly essential to spread awareness about the ill effects of selfie addiction among the youngsters to curb this addiction earlier.


Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Sarwat Memon

Background: The palatal rugae are special constructions that are inalterable in their position and pattern during the lifestyles of an individual. This imparts them an exceptional role in the forensic dentistry and may play potential role in malocclusion identification. This study was aimed to see association of rugae pattern with sagittal skeletal malocclusion in orthodontic patients visiting tertiary care hospital. Methods: This cross-sectional examination was completed on pretreatment records (lateral Cephalometric radiographs and maxillary dental casts) of 384 subjects at the orthodontic department of Ziauddin Dental Hospital, Karachi. The study duration was from January to July 2019. The samples were sub-divided into three sagittal skeletal groups based on ANB angle proposed by Steiner’s on lateral Cephalometric radiographs (Class I with ANB angle between 0° to 4°; Class II: ANB angle greater than 5°; Class III: ANB angle less than 0°). The shapes of three most-anterior primary rugae were then evaluated bilaterally using Kapali et al., Classification. Chi Square test was applied to find association of rugae pattern among sagittal skeletal malocclusions groups. Results: Circular and curved rugae shapes were the most prevalent in all skeletal malocclusions. The primary palatal rugae pattern was seen to be significantly different among three skeletal malocclusion groups (p<0.05). The right and left sided palatal rugae pattern showed significant difference in all three skeletal malocclusion groups (p<0.05). Conclusion: The present study showed no specific palatal rugae pattern associated with sagittal skeletal malocclusion. Further studies on larger sample and use of modern 3D technologies to scan the maxillary casts are required for results that are more precise.


Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2017 ◽  
Vol 6 (05) ◽  
pp. 5373
Author(s):  
Prabha Ponnusamy* ◽  
Radhika Katragadda ◽  
Thyagarajan Ravinder

Asymptomatic bacteriuria (ASB), most common during pregnancy is endangering as it may lead to maternal and fetal complications. Various organisms causing ASB combats the host defense mechanisms through virulence factors exhibited by them. In order to understand the pathogenesis and sequelae of infections, virulence factors like hemolysin production, gelatinase production, haemagglutination, biofilm production and many more should be identified. Hence, we aimed at studying the distribution of virulence factors among each organism causing asymptomatic bacteriuria in pregnant females attending a tertiary care hospital. Materials and Methods: This cross-sectional study was conducted in Department of Microbiology over a period of one year and six months (January 2014 to June 2015) at a tertiary care teaching hospital. A total of 1000 urine samples were included in study taken from pregnant women with asymptomatic bacteriuria. Isolation, identification of organisms was done according to standard microbiological techniques and virulence factors for individual organisms by phenotypic method were tested. Results: Out of 1000 samples screened for ASB, organisms were isolated in following frequency distribution: Escherichia coli, the commonest 54/118 (45.76%), Klebsiella pneumoniae 21/118 (17.80%), Staphylococcus aureus 19/118 (16.10%), Staphylococcus saprophyticus 10/118 (8.45%), Enterococcus faecalis 9/118 (7.63%), Pseudomonas aeruginosa 3/118 (2.54%) and Proteus mirabilis 2/118 (1.69%). Virulence factors for individual organisms and biofilm detection for all organisms were done. Conclusion: Multifactorial mechanisms determine the pathogenicity of an organism and it needs to be explored by analyzing each virulence factor and mechanism of invasion in combating the host defense systems. Hence analyzing the phenotypic expression of each virulence factor helps in better understanding about the complications of ASB.


Author(s):  
Vanajakshamma Velam ◽  
Vyshnavi Kancherla ◽  
Latheef Kasala ◽  
Anusha Kancherla ◽  
Mounica Reddy Pillaram

Abstract Background This study was an attempt to assess and compare the gender-wise lifestyle patterns and well-being status among the employees of a tertiary care teaching hospital. Material and Methods This is a cross-sectional, questionnaire-based study conducted at a tertiary care hospital between May and August 2019. A total of 777 employees belonging to both genders (male and female) and working at different professional levels were assessed. All the enrolled employees were subjected to a comprehensive study tool consisting of various dimensions of their health, which included physical, mental, social, spiritual and intellectual health dimensions. Results Among the participants, 327 (42.1%) were male and 450 (57.9%) were female. There was no significant difference in the mean age of male (37.91 ± 7.52) and female (36.85 ± 8.16) employees (p = 0.07). A significantly higher proportion of diabetes and hypertension were seen in male employees (9.8% and 14.4%, respectively) than in female (5.6% and 6.2% respectively). The overall well-being was better in male employees than in females and was statistically significant (p < 0.0001). We found that male employees had statistically significant better well-being in terms of physical, mental and social health whereas female employees had intellectual health. Conclusion The overall well-being in healthcare staff was good at our tertiary care hospital, and the outstanding/good well-being rate was higher in male employees than in female employees. Female employees experienced risks with regard to their physical health.


Infection ◽  
2021 ◽  
Author(s):  
Johanna Koehler ◽  
Barbara Ritzer ◽  
Simon Weidlich ◽  
Friedemann Gebhardt ◽  
Chlodwig Kirchhoff ◽  
...  

AbstractAdditional treatment options for coronavirus disease (COVID-19) are urgently needed, particularly for populations at high risk of severe disease. This cross-sectional, retrospective study characterized the outcomes of 43 patients with nosocomial severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection with and without treatment using monoclonal SARS-CoV-2 spike antibodies (bamlanivimab or casirivimab/imdevimab). Our results indicate that treatment with monoclonal antibodies results in a significant decrease in disease progression and mortality when used for asymptomatic patients with early SARS-CoV-2 infection.


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