scholarly journals PRETERM LABOUR

2018 ◽  
Vol 25 (09) ◽  
pp. 1342-1345
Author(s):  
Saima Ashraf ◽  
Shahida Parveen ◽  
Shahzad Alam
Keyword(s):  
Preterm Labour ◽  
Serum Magnesium ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Serum Magnesium Level ◽  
Amniotic Fluid Index ◽  
Singleton Pregnancy ◽  
Cross Sectional ◽  
History Of ◽  
Age Range

Objectives: To determine the frequency of hypomagnesaemia in women withpreterm labour. Study Design: Cross sectional study. Settings: Department of obstetrics &gynaecology Nishtar Hospital Multan. Duration of Study: From 10th November 2016 to 10th May2017. Subject and Methods: A total of 219 pregnant women with singleton pregnancy, pretermlabour and parity 1 – 4 were included in the study. Women with history of diabetes, hypertensionsmoking and polyhhydramnious amniotic fluid index (AFI)>25 cm on ultrasound were excluded.Venous blood was drawn from entire subjects to evaluate the serum magnesium level and sentimmediately to laboratory for analysis venous blood samples were obtained by venepunctureand collected in lithium heparin specimen bottles. Data was collected for hypomagnesaemia.Results: Age range in this study was from 20 to 40 years with mean age of 30.356±3.60 years,mean parity 1.936± 0.96, mean gravida 2.936 ± 0.96, mean gestational age 32.000±2.25weeks and mean BMI was 27.337 ± 1.67 kg/m2. Majority of the patients were from 20 – 30 years(51.1%). History of preterm delivery was 17.4%. Majority of patients belong to middle economicstatus (66.2%). Hypomagnesaemia was seen in 37.9% patients. Conclusion: it is concludedthat low serum magnesium (hypomagnesaemia) is associated with preterm onset of labour.Maternal hypomagnesaemia may be used as a predictor of preterm labour.

scholarly journals Association between serum magnesium and obesity in postmenopausal women

2018 ◽  
Vol 6 (9) ◽  
pp. 3156
Author(s):  
Alka Yadav ◽  
Madhuri Gupta ◽  
R. C. Gupta
Keyword(s):  
Postmenopausal Women ◽  
Magnesium Deficiency ◽  
Serum Magnesium ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Magnesium Concentration ◽  
Control Group ◽  
Excess Body Weight ◽  
Cross Sectional ◽  
Dietary History

Background: Obesity is a complex, multifactorial condition in which excess body weight may put a female at risk of serious health problems such as hypertension, dyslipidemia, diabetes mellitus and cardiovascular diseases. Magnesium deficiency is reported to be associated with obesity in children and adolescents. An inverse relationship has been reported between serum magnesium and estrogen levels in women. It is not known whether magnesium deficiency may have a role in genesis of obesity in women after menopause. Therefore, the present study was planned to compare serum magnesium levels in obese and non-obese postmenopausal women and to find out the relationship, if any, between serum magnesium levels and obesity.Methods: This cross-sectional study was conducted in the department of Biochemistry at National Institute of Medical Sciences and Research, Jaipur, Rajasthan on fifty subjects over a period of six months. Twenty-five obese postmenopausal women (BMI ≥ 30) having their final menstrual period at least one year prior to the study were taken as the study group and twenty-five non-obese (BMI ≤ 22.9) post-menopausal women were taken as control group. All subjects were asked to give detailed dietary history using Food Frequency Questionnaire (FFQ). Venous blood samples were collected after an overnight fast for estimation of serum total magnesium in all subjects.Results: Obese postmenopausal women had significantly higher weight (78.36±0.064kg) and BMI (32.68±1.7kg/mt2) compared to non-obese postmenopausal women (wt. 54.72±4.80kg and BMI 21.75±1.68kg/mt2). The mean±SD serum magnesium concentration found in the obese postmenopausal women was 1.40±0.45mg/dl as compared to 2.03±0.49 mg/dl in the non-obese group. Pearson’s correlation analysis showed a significant (r = -0.9) negative correlation between BMI and serum magnesium in postmenopausal women.Conclusions: Serum magnesium was lower in obese postmenopausal women as compared to that in non-obese postmenopausal women. Serum magnesium was negatively correlated with BMI. Magnesium supplementation may be useful in prevention of obesity after menopause.

scholarly journals Hepatitis C in pregnancy: an observational study highlighting its association with maternal parameters

2019 ◽  
Vol 8 (1) ◽  
pp. 344
Author(s):  
Bushra . ◽  
Ambreen Ghori ◽  
Azra Ahmed ◽  
Najma Dalwani ◽  
Mushtaque Ali Shah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Previous History ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Prior History ◽  
Singleton Pregnancy ◽  
Cross Sectional ◽  
History Of

Background: Pregnancy is a very crucial time in a woman’s life. In this period of time, not only multiple physiological alterations effect the usual health status but also makes women more vulnerable to contract infection and face negative sequalae. Hepatitis C, a blood borne viral infection serve the similar fate when encountered by pregnant ladies. This study is based on exploring the prevalence of the Hepatitis C virus seropositivity among pregnant population. Moreover, we also evaluated the major risk factors leading to the infection in these mothers. Besides this, infected mothers were studied for their pregnancy outcomes.Methods: In this study 114 pregnant females were observed for this cross-sectional study. It was conducted in Gynecology Unit- 1, Liaquat University Hospital Hyderabad, for the period of January 2017 to July 2017. Chi square test was applied for statistical analysis on SPSS version 16. The criteria for enrollment in the study was set to be a pregnant lady belonging to age group 20-35 years; having singleton pregnancy; was a booked case at the hospital with compliant to antenatal follow ups; admitted to the labor room for delivery. All the non-pregnant ladies, whom had co morbid conditions such as hypertension or diabetes or had infected with hepatitis B or D were excluded from the study. Furthermore, pregnant ladies with multiple gestion or those who were either diagnosed of hepatitis C prior to conceive or had a previous history of hepatitis C were also excluded.Results: Present study revealed that out of 114, 10(8.8%) pregnant ladies were found seropositive for Hepatitis C virus. Prior history for transfusion of blood was the Foremost risk factor discovered, with 60.5% women reported this. History of surgery was the 2nd commonest factor and 43.9% had this in their medical records. On the other hand, only 8.8% women gave the history for previous evacuation. While observing pregnancy outcomes, we found 48.2% neonates had low birth weight, 41.2% were born preterm and 21.1% had low APGAR score.Conclusions: In a nutshell hepatitis c is prevalent in the pregnant population of this region and showing its effects in the form of compromised pregnancies. History of blood transfusion and previous surgery were found to be chief risk factors in the study.

ASSOCIATION OF SERUM MAGNESIUM LEVEL WITH RESISTANT HYPERLIPIDEMIA IN DIABETIC AND HYPERTENSIVE PATIENTS

2021 ◽  
pp. 33-35
Author(s):  
Manish Kumar ◽  
Syed Yousuf Faisal ◽  
Sudhir Chandra Jha ◽  
Debarshi Jana
Keyword(s):  
Serum Magnesium ◽  
Cross Sectional Study ◽  
Magnesium Level ◽  
Lipid Lowering ◽  
Diabetic Patients ◽  
Serum Magnesium Level ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Present Cross Sectional Study ◽  
Lipid Lowering Agents

Introduction: Both diabetes mellitus and hypertension are aspects of metabolic syndrome. Objectives: The aim of this study was to determine the relationship between serum magnesium level with resistant hyperlipidemia in a group of diabetic and hypertensive patients. Patients And Methods: The present cross- sectional study was carried out on 90 hypertensive and diabetic patients in Medicine Department of DMCH, Laheriasarai, Bihar, (45 hypertensive and 45 diabetic patients). Included patients had high triglyceride levels despite 8 weeks of treatment with lipid-lowering agents. Results: There was an inverse signicant relationship between serum magnesium and triglyceride levels in diabetic patients (P=0.002, r=-0.458), however, this correlation was not signicant in hypertensive patients (P=0.754, r=0.048). Conclusion: This study showed, serum magnesium may affect triglycerides levels in diabetic patients, however, our nding requires further investigation with larger population

COVID-19: An Experience from a Tertiary Care Hospital of Nowshera

2020 ◽  
Vol 24 (2) ◽  
pp. 149-155
Author(s):  
Hamzullah Khan ◽  
Mohammad Zahid Khan ◽  
Mian Mohammad Naveed
Keyword(s):  
Tertiary Care ◽  
Relevant Information ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Epidemic Area ◽  
History Of ◽  
Severity Of The Disease ◽  
Age Range

Objective: To determine the frequency of COVID-19 and characteristics of patients presenting to the COVID-19 clinic at Qazi Hussain Ahmed Medical Complex (QHAMC) Nowshera. Methodology: This cross-sectional study was conducted from 21st Feb 2019 to April 8, 2020, in QHAMC Nowshera. Relevant information was collected on a pre-designed Performa prepared following the objectives of the study. Results: Out of 220 patients, 165(75%) were males, and 55(25%) females. 96(43.6%) of the patients were in the age range 18-30 years followed by 52(23.6%) in age range 31-45years and 17(7.7%) with age>60 years etc. Out of total the nasopharyngeal swabs of 26(11.6%) strong suspects were sent for PCR testing. 208(94.5%) were sent home while 12(5.5%) were advised quarantine. Forty-seven (21.4%) had a travel history to an epidemic area in the last 14 days. 51(23.2%) had a positive history of contact. Eighty-five (38.6%) had a fever and sore throat followed by 27(12.3%) with (fever & cough), 24(10.9%) with (cough and shortness of breath/dyspnea) and 14(6.4%) with a simple flue, etc. Out of 26 cases, 6(2.7%) were COVID-19 Positive, 12(5.5%) were negative and results of 8(3.6%) were still awaited. The PCR repeated the test for confirmed cases showed;  4(1.8%) negative, one died and one was refractory positive.  A positive correlation (p=0.03, r=0.4) of an increase in age with the severity of the disease/outcome was recorded. Conclusion: The frequency of infectivity with COVID-19 was 2.6%. A higher number of patients with mild symptoms attend the COVID clinic. The rate of infection and mortality was higher in age> 60 years.

scholarly journals Evaluation of Serum Magnesium Level in Preeclampsia

2018 ◽  
Vol 10 (1) ◽  
pp. 10-15
Author(s):  
HL Roy ◽  
S Nargis ◽  
SH Mahmud ◽  
NWB Jahan ◽  
MS Hossain ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Serum Magnesium ◽  
Colorimetric Method ◽  
Magnesium Level ◽  
Medical Complication ◽  
Serum Magnesium Level ◽  
Cross Sectional ◽  
The Mean ◽  
Age Range

Preeclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Reduced serum magnesium level is found to be associated with elevated blood pressure in preeclampsia. The purpose of this cross-sectional study is to evaluate the serum magnesium level in preeclamptic women. For this study 50 preeclamptic patients, with age range 20 to 40 years having gestational age range from 20 to 40 weeks and 50 age and gestational age matched normotensive pregnant women having no proteinuria were enrolled. Serum magnesium was measured by colorimetric method. The mean(±SD) age and mean(±SD) gestational age of preeclampsia was not significantly different from those of normotensive pregnant women (p=0.203 and p=0.251 respectively). The mean(±SD) body mass index of the preeclamptic patients was significantly higher compared to that of normotensive pregnant women (p<0.001). The mean(±SD) serum magnesium level was 3.37±2.05 mg/dl in preeclamptic group and 2.87±1.38 mg/dl in normal pregnant women; the level did not differ significantly between the subject of preeclampsia and normal pregnant women (p=0.153). Findings of this study suggest that serum magnesium has no association with preeclampsia.Bangladesh J Med Biochem 2017; 10(1): 10-15

scholarly journals The Association Between Uric Acid and Symmetric Dimethylarginine Levels in the Patients Undergoing Twice-weekly Hemodialysis

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Aida Lydia ◽  
Yassir Yassir ◽  
Rudy Hidayat ◽  
Suhendro Suwarto
Keyword(s):  
Uric Acid ◽  
Venous Blood ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Bivariate Analysis ◽  
Symmetric Dimethylarginine ◽  
Cross Sectional ◽  
Increased Risk ◽  
History Of

Background: Uric acid (UA) levels are associated with increased risk of cardiovascular events and mortality in hemodialysis patients. However, there are still conflicting data on the mechanism of increased risks related to uric acid levels. Objectives: This study assessed the association between uric acid levels and symmetric dimethylarginine (SDMA), as a marker of cardiovascular disease, in the subjects undergoing hemodialysis twice weekly. Methods: This was a cross-sectional study conducted in a tertiary hospital in Jakarta, Indonesia. We included all the adults who underwent hemodialysis twice weekly for at least three months in our hospital. Subjects already on uric acid lowering therapy, pregnant or lactating women and those with a history of malignancy were excluded. Uric acid and SDMA levels were measured at the same time in pre-dialysis venous blood samples. Bivariate analysis was performed using the Mann-Whitney U test or one-way ANOVA. Results: A total of 126 subjects were included. The median level of UA was 8.4 mg/dL (IQR: 2.6, min: 4.1, max: 13.6), and 72 subjects (57.14%) had UA levels of 8 mg/dL or higher. The median SDMA level was 535.5 (312.7) mmol/dL (min: 119.7, max: 1895.5). Subjects with UA levels > 8 mg/dL had significantly higher SDMA levels compared to subjects with UA levels < 8 mg/dL (550.1 (IQR: 357.25) vs 491.35 (IQR: 181.1), P: 0.0475). Conclusions: In twice-weekly hemodialysis patients, UA levels above 8 mg/dL were associated with increased SDMA levels.

scholarly journals Hypomagnesemia and Poor Glycemic Control Among Palestinian Type 2 Diabetic Patients: A Cross-Sectional Study

2021 ◽  
Author(s):  
Mohmmad Hamarshih ◽  
Suha Hamshari ◽  
Zaher Nazzal ◽  
Farha Abu Snobar ◽  
Rawa Mletat ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Glycemic Control ◽  
Serum Magnesium ◽  
Cross Sectional Study ◽  
Magnesium Level ◽  
Poor Glycemic Control ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of

Abstract Background: Hypomagnesemia has been shown to have a significant impact on both glycemic control and diabetes complications in type 2 Diabetes Mellitus (T2DM) patients. This study aims to assess the prevalence of hypomagnesemia in T2DM patients and find the association between serum magnesium levels and outcomes relevant to glycemic control and diabetic complications.Methods: A cross-sectional study was conducted and included 373 patients (222 males and 151 females). Serum magnesium levels were measured by the Colorimetric Endpoint Method using the Cobas C501system. Hypomagnesemia was determined to be a serum magnesium level <1.6 mg/dL. In addition, the following data were also obtained; patients' characteristics, anthropometric measurements, smoking status, HbA1c, co-morbidities, and therapeutic management. Results: Patients' mean age was 56.2 ±10.8 years, 24.6% were smokers, and most were overweight or obese. About 60% have a history of hypertension, and the majority have had diabetes for more than ten years. Their mean HbA1c level was 8.5±2. The prevalence of hypomagnesemia was 11% (95% CI: 8%-14.6%). It was found to be significantly higher among females (adjusted OR: 2.7, 95%CI: 1.2%-5.8%), patients with HbA1c ≥ 8% (adjusted OR: 2.4, 95%CI: 1.1%-5.5%), and patients with a history of diabetic retinopathy (adjusted OR: 2.7, 95%CI: 1.1%-7.1%). Conclusions: the study showed that hypomagnesemia is more prevalent in females and is associated with diabetic retinopathy and poor glycemic control. Having a sufficient magnesium level may be associated with better glycemic control and a reduced occurrence of complications.

scholarly journals Serum Magnesium Levels among Pregnant Women with and without Complications: A Cross-sectional Study

2020 ◽  
Author(s):  
Santhini Gopalakrishnan Sethulekshmi ◽  
S Sumathy ◽  
Banani Dutta
Keyword(s):  
Pregnant Women ◽  
Magnesium Deficiency ◽  
Serum Magnesium ◽  
First Trimester ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
History Of ◽  
Student’S T

Introduction: Pregnancy is a period that is characterised by remarkable physiological changes which are needed to support the growing fetus. Micronutrients play a crucial role in the maintenance of pregnancy. Among the micronutrients, magnesium has got ample amount of clinical relevance to pregnancy. Magnesium deficiency has been associated with reproductive risk during pregnancy such as anaemia, pre-eclampsia, eclampsia, fetal growth retardation, preterm labour, low intrauterine growth rate and leg cramps. Aim: To find out whether there was significant difference in the magnesium levels among pregnant women with and without pregnancy related complications and also to find out whether the magnesium levels differed significantly among the three trimesters. Materials and Methods: This was a cross-sectional study done among 240 pregnant patients from different trimesters attending the Obstetrics and Gynaecology Outpatient Department. Out of them 164 women had complications like pre-eclampsia, Gestational Diabetes Mellitus, leg cramps and history of abortions. Demographic details were obtained from all the women. BMI was calculated for each subject using the formula BMI=weight(kg)/height(m2). Haemoglobin was assessed in all samples using cyanmethaemoglobin method. Magnesium levels were analysed in the all samples using automated analyser in the Biochemistry laboratory. Student’s t-test was used to compare the levels of magnesium among the groups with and without complications. ANOVA test was used to compare the three trimesters. Results: The pregnant women were divided into three groups based on the different trimesters in which the samples were taken. Magnesium levels among the women in the first trimester were (2.96±0.83) second trimester (2.99±1.48) and third trimester (3.05±1.48) respectively. Women with previous abortions were found to have less magnesium levels (2.71) compared to women without a history of abortion (3.11) and value was found to be statistically significant (p<0.007) and magnesium levels among vegetarians (2.45) were lower than non vegetarians (3.08) and it was found to be statistical significant (p<0.013). There was no significant difference in the magnesium levels among pregnant women with complications and those without complications. Conclusion: The study shows the importance of maintaining the magnesium levels among pregnant women. There was no difference in the magnesium levels among the three trimesters. Study also points out the influence of parity, diet and occupation of pregnant women on the levels of magnesium.

scholarly journals Association of polycystic ovary syndrome with insulin resistance and glucose transporter GLUT 4.

2020 ◽  
Vol 27 (10) ◽  
pp. 2182-2186
Author(s):  
Roohi Jabbar ◽  
Rukhshan Khurshid ◽  
Uzma Jabbar ◽  
Mudassir Zia ◽  
Abeera Mazhar Siddiqui ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Glucose Transporter ◽  
Fasting Glucose ◽  
Polycystic Ovary ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Glut 4 ◽  
History Of ◽  
Age Range ◽  
Study Setting

Objectives: The study was designed to find out the association of PCOS with insulin resistance and GLUT4. Study Design: Cross Sectional study. Setting: Outdoor Department of Sir Ganga Ram Hospital Lahore. Period: March 2016 to December 2016. Material & Methods: 37 PCOS women visited Outdoor Department of Sir Ganga Ram Hospital Lahore. Their age range was 25- 36 years. 20 ages matched medical staff of the Sir Ganga Ram Hospital, Lahore with no history of any disease were selected as control. Rotterdam’s criteria were used to confirm PCOS. Levels of circulating insulin, GLUT 4 and fasting glucose were estimated. Results: Mean age of PCOS patients and of controls was 30.55 and 29.00 years respectively. Values of BMI were insignificantly raised in PCOS in comparison to controls. Levels of circulating GLUT-4, fasting glucose, insulin and resistance of insulin were increased significantly in women with PCOS in comparison to the controls. Decreased ratio of glucose to insulin was seen in PCOS women in comparison to their controls. Conclusion: A good association of PCOS was observed with insulin mediated release of glucose transporter GLUT 4 and insulin resistance.

scholarly journals Association of serum magnesium level with resistant hyperlipidemia in diabetic and hypertensive patients

2019 ◽  
Vol 9 (1) ◽  
pp. e07-e07
Author(s):  
Pardis Kaveh ◽  
Afsaneh Malekpour Tehrani ◽  
Saeid Mardani
Keyword(s):  
Serum Magnesium ◽  
Cross Sectional Study ◽  
Magnesium Level ◽  
Lipid Lowering ◽  
Diabetic Patients ◽  
Serum Magnesium Level ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Present Cross Sectional Study ◽  
Lipid Lowering Agents

Introduction: Both diabetes mellitus and hypertension are aspects of metabolic syndrome. Objectives: The aim of this study was to determine the relationship between serum magnesium level with resistant hyperlipidemia in a group of diabetic and hypertensive patients. Patients and Methods: The present cross-sectional study was carried out on 90 hypertensive and diabetic patients who referred to outpatient university clinic in Shahrekord (45 hypertensive and 45 diabetic patients). Included patients had high triglyceride levels despite 8 weeks of treatment with lipid-lowering agents. Results: There was an inverse significant relationship between serum magnesium and triglyceride levels in diabetic patients (P=0.002, r=-0.458), however, this correlation was not significant in hypertensive patients (P=0.754, r=0.048). Conclusion: This study showed, serum magnesium may affect triglycerides levels in diabetic patients, however, our finding requires further investigation with larger population.

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