scholarly journals Pattern of paediatric congenital heart diseases.

2021 ◽  
Vol 28 (11) ◽  
pp. 1678-1681
Author(s):  
Khurram Shahnawaz ◽  
Farhan Zahoor ◽  
Bushra Madni ◽  
Muhammad Imran ◽  
Muhammad Naveed ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Diseases ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Related Data ◽  
And Gender ◽  
Male To Female ◽  
Heart Lesions ◽  
Study Setting

Objective: To find out pattern along with age and gender wise distribution of congenital heart disease (CHD). Study Design: Cross Sectional study. Setting: Department of Pediatrics, Sughra Shafi Medical Complex, Narowal. Period: January 2019 to February 2020. Material & Methods: During the study period, a total of 151 children aged between 1 month to 15 years as confirmed case of CHD according to echocardiography were enrolled for this study. Gender, age categories, area of residence and types of CHDs were represented as frequency and percentages. Patients with different types of CHDs were distributed between both gender and different age categories. SPSS version 26.0 was used to handle and analyze all study related data. Results: During the study period, a total of 151 confirmed cases of CHD were enrolled. There were 82 (54.3%) male and 69 (45.7%) female representing a male to female ratio of 1.2:1. Most of the cases were aged less than 1 year. There were 118 (78.1%) children below 1 year of age while 22 (14.6%) between 1 to 5 years of age and 11 (7.3%) above 5 years of age. Ventricular septal defect (VSD) and ASD were noted to be the most frequent types of acyanotic heart lesions in 41 (27.2%) and 29 (19.2%) cases respectively whereas TOF was the most frequent type of cyanotic heart lesion in 23 (15.2%) cases. Conclusion: VSD followed by ASD and TOF were noted to be the most frequent types of CHD.

scholarly journals Sensitivity of common bacterial pathogens causing pneumonia in children age 1 month to 5 years

2019 ◽  
Vol 26 (09) ◽  
pp. 1393-1397
Author(s):  
Farman Ali ◽  
Rifaq Zeb ◽  
Farid Ullah ◽  
Junaid Zeb
Keyword(s):  
Lung Parenchyma ◽  
Cross Sectional Study ◽  
Study Data ◽  
Klebsiella Pneumonia ◽  
Cross Sectional ◽  
Streptococcus Pneumonia ◽  
Female Ratio ◽  
E Coli ◽  
Male To Female ◽  
Study Setting

Background: Pneumonia is defined as inflammation of lung parenchyma. Aim of the current study was to identify the culture and sensitivity of bacteria causing pneumonia in one month to 5 years of age. Study Design: Cross sectional study. Setting: Department of Pediatric Medicine, Khyber Teaching Hospital (KTH), Peshawar. Period: December 2016 to March 2018. Material & Methods: Total 292 patients were randomly included in study. Data were collected by pre designed Performa and analyzed by SPSS 21. Results: Mean age of patients was 2.7 ± 1.2 years. Male to female ratio was 3:2. Culture report showed 123(42.1%) were Staphylococcus Aureus positive, 87(29.8%) streptococcus pneumonia, 75(25.7%) Hemophilus Influenza, 3(0.01%) Pseudomonas aeruginosa, 2(0.0068%) Klebsiella pneumoniae, 2 (0.0068%)  E.coli positive. All the bacteria were sensitive to commonly used antibiotics unless we observed resistance of H. Influenza against clarithromycin and Co amoxiclav. In rest of seven cases, out of total two cases of E. coli both were sensitive to amikacin while resistance to amoxil and co amoxiclave. Out of total three pseudomonas cases, two cases were resistance to ceftriaxone and amoxil, one was sensitive to ceftriaxone, while all three were sensitive to amikacin, two cases were of klebsiella pneumonia and both of them were sensitive to amikacin while resistant to amoxil. Conclusion: Most common organism causing pneumonia in one month to 5 years of age is S aureus followed by S pneaumoniae, H influenza, Paurogenosia, klabsiella and E.coli. Most of these organisms were sensitive to amoxil, ampiclox, cefotaxime and ceftriaxone while resistance of H influenza was observed to clarithromycin and co amoxiclave.

scholarly journals Anthropometric assessment in children with congenital heart disease

2018 ◽  
Vol 5 (2) ◽  
pp. 634 ◽  
Author(s):  
Begam Rubia ◽  
Anjali Kher
Keyword(s):  
Congenital Heart ◽  
Heart Diseases ◽  
Nutritional Therapy ◽  
Age Group ◽  
Female Ratio ◽  
Dietary History ◽  
And Gender ◽  
Male To Female ◽  
Anthropometric Assessment ◽  
Control Study

Background: Congenital Heart Diseases (CHD) are often associated with malnutrition with prevalence of 64%. Malnutrition in CHD increases morbidity and mortality in these children and hence it is essential to assess the nutritional status of the children with CHD so that proper nutritional therapy and rehabilitation can be done.Methods: In this case control study 126 cases of un operated CHD in the age group of >28 days to 10 years and 126 age and gender matched controls without CHD were studied during a period of 2 year. Informed consent from the parents was obtained and they were interviewed using pre-validated proforma and relevant clinical examination, detailed anthropometric assessment was done of all cases and control.Results: Male to female ratio was 0.9:1. Maximum cases were in age group of 1 to 5 years. Acyanotic CHD was seen in 80.16% and cyanotic CHD was seen in 19.84%. Stunting was seen in 58.72% cases and in 41.26% of controls. 82.53% of cases and 24.6% of controls were underweight. Conclusions: The prevalence of acyanotic CHD was more common than cyanotic CHD. In acyanotic CHD cases VSD was commonest and in cyanotic CHD cases TOF was the commonest lesion. The overall prevalence of underweight and stunting was high in cases than controls. In acyanotic CHD underweight and stunting was high than cyanotic CHD. In this study malnutrition correlated significantly with congestive heart failure, low hemoglobin level, poor dietary history and pulmonary hypertension and this was statistically highly significant.

Frequency of High MELD Score in Cirrhotic Patients undergoing Liver Resection due to Hepatocellular Carcinoma

2021 ◽  
Vol 15 (9) ◽  
pp. 2841-2843
Author(s):  
Muhammad Omer Farooq ◽  
Niaz Ahmed ◽  
Hassan Nadeem ◽  
Kashif Rafi ◽  
Sadia Jabbar ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Resection ◽  
Cross Sectional Study ◽  
Meld Score ◽  
Cross Sectional ◽  
Female Ratio ◽  
Score Study ◽  
Insignificant Difference ◽  
Cirrhotic Patients ◽  
Male To Female

Objective: To determine the frequency of high MELD score in cirrhotic patients undergoing liver resection due to hepatocellular carcinoma also compare the frequency of mortality in patients with high or low MELD score. Study Design: Cross sectional study Place and Duration: Department of Gastroenterology, Shaikh Zayed Hospital, Lahore. Duration: 6months i.e. 23 12-2017 to 22-06-2018. Methodology: 75 patients were enrolled. Then blood sample was obtained. Reports assessed and MELD score calculated. Scores were labeled as high or low. Patients underwent liver resection according to BCLC. The mortality was noted. All the collected data was entered and analyzed on SPSS version 22. Results: In this study out of total 75 cases 60 were males and 15 females. The mean age of patients was 39.44±9.76 years, male to female ratio was 4:1. Low MELD class was noted in 45 (60%) cases and high MELD class noted in 30(40%) cases. Mortality occurred in 27(36%) cases. Insignificant difference found between the MELD class with mortality. Conclusion: High MELD score was seen in 40% cirrhotic patients undergoing liver resection due to HCC. Post HCC resection, mortality occurred in 36% patients within three months of surgery. No significant association was found between the mortality and MELD score. Keywords: MELD, Hepatocellular Carcinoma, Mortality, Cirrhosis

HIV Prevalence and Frequency of Risk Behavior in Injecting Drug Users Entering Treatment and Out of Treatment: A Cross-Sectional Study in Five Italian Cities

1994 ◽  
Vol 24 (3) ◽  
pp. 527-535 ◽  
Author(s):  
Giovanni Rezza ◽  
Stefania Salmaso ◽  
Damiano Abeni ◽  
Giovanna Brancato ◽  
Alessandra Anemona ◽  
...  
Keyword(s):  
Risk Behavior ◽  
Drug Users ◽  
Injecting Drug Users ◽  
Cross Sectional Study ◽  
Hiv Prevalence ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Outreach Programs ◽  
Male To Female

We conducted a study to describe current patterns of drug-related behaviors, and to identify characteristics that may distinguish injecting drug users entering treatment from those out of treatment, in five Italian cities. Overall, 1,180 subjects were recruited — 568 entering treatment and 612 out of treatment. Male to female ratio was 6.6:1. The median age was similar in the two groups. A high proportion of injecting drug users recruited out of treatment had been in treatment at least once. HIV prevalence among injecting drug users entering treatment was not higher than that of those who were out of treatment. Furthermore, a large proportion of injecting drug users who still were out of treatment reported having adopted safe behaviors. The results of the study emphasize the need to implement outreach programs aimed at harm reduction.

scholarly journals Does Static Intra Access Pressure Monitoring of Arteriovenous Fistulas Predicts Intra Access Stenosis?

2021 ◽  
Vol 4 (03) ◽  
Author(s):  
Abaid ur Rehman ◽  
Muhammad Imran Khan ◽  
Omer Sabir ◽  
Muhammad Mohsin Riaz ◽  
Mubashar Dilawar ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Vascular Access ◽  
Doppler Ultrasonography ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Arteriovenous Fistulas ◽  
Doppler Us ◽  
Sensitivity Specificity ◽  
Male To Female

The initiation of hemodialysis in patients with chronic kidney disease (CKD) requires vascular access formation. The choice of vascular access for individual patient depends on various factors however arteriovenous fistula (AVF) is conventionally considered to be the vascular access of choice. Once hemodialysis is initiated through a mature AVF, there is an ongoing need for surveillance of the AVF to ensure adequate function and prevent vascular access issues among which flow obstruction (both inflow and outflow) remains the most important. AVF stenosis can potentially lead to inadequate dialysis delivery and thrombosis thus leading to access loss. Physical examination and AVF Doppler ultrasonography (DUS) are useful for evaluation of stenosis in the  arteriovenous connection and the outflow tract. Periodic assessment of the AVF with Static Intra access Pressure (SIAPR) determination may be a reliable means of predicting vascular access stenosis. Material & Methods  A cross sectional study carried out at Department of Nephrology, Fatima Memorial Hospital, Lahore from July 2018 to December 2018. In total 113 patients were included, and all patients underwent SIAPR assessment and Doppler Ultrasound of AVF. Results Mean age of the patients was 56.81±9.38 years, male to female ratio of the patients was 1.8:1. In this study the SIAPR was suggestive of  stenosis in 87(76.99%) patients. The sensitivity, specificity and diagnostic accuracy of SIAPR against Doppler US of the AVF for detection of stenosis was 75.86%, 22.62% & 36.28% respectively Conclusion SIAPR has low specificity and diagnostic accuracy compared to Doppler US for detection of AVF stenosis.

scholarly journals Frequency of sensorineural hearing loss in children with bacterial meningitis.

2020 ◽  
Vol 27 (12) ◽  
pp. 2729-2733
Author(s):  
Rabia Saleem Safdar ◽  
M Faisal Mehar ◽  
Madiha Naz ◽  
Afsheen Asghar Khan ◽  
Nusrat Buzdar ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Cross Sectional Study ◽  
Sensorineural Hearing ◽  
Outcome Variable ◽  
Cross Sectional ◽  
And Gender ◽  
Evoked Response Audiometry ◽  
Study Setting

Objectives: To determine the frequency of sensorineural hearing loss (SNHL) in children with bacterial meningitis. Study Design: Cross Sectional study. Setting: Department of Paediatric Medicine Nishtar Hospital, Multan. Period: October 2019 to March 2020. Material & Methods: The study was conducted after permission from ethical committee. A total of 151 patients admitted with bacterial meningitis were enrolled. Apart from the presenting complaints, necessary information like the age and gender were noted. Examination of the child was done to assess the condition of child. Brainstem evoked response audiometry (BERA) test was performed before discharge of the patient from the hospital. The outcome variable that is SNHL in bacterial meningitis assessed by BERA test was noted in a specifically designed Performa. Results: Out of total of 151 patients, males were 83 (55%) while females 68 (45%). Overall mean age was 11.85+6.12 months. SNHL was found in 26 (17.2%) children. There was no significant effect of age or gender on the frequencies of SNHL. Conclusion: SNHL is a frequently encountered complication in our population of children with bacterial meningitis. SNHL should be carefully sought out and properly diagnosed in all the patients presenting with bacterial meningitis.

scholarly journals Comparison of Led Fluorescent Microscopy and the Gene Xpert MTB/RIF Assay in Diagnosis of Pulmonary and Extrapulmonary Tuberculosis

2019 ◽  
Vol 6 ◽  
pp. 127-132
Author(s):  
Sanam Thapa Magar ◽  
Gokarna Ghimire ◽  
Pradeep Kumar Shah
Keyword(s):  
Pulmonary Tuberculosis ◽  
Extrapulmonary Tuberculosis ◽  
Fluorescent Microscopy ◽  
Cross Sectional Study ◽  
Smear Microscopy ◽  
Cross Sectional ◽  
Female Ratio ◽  
Standard Guideline ◽  
National Tuberculosis ◽  
Male To Female

Objectives: The objective of this study was to evaluate Gene Xpert MTB/RIF Assay and anid fast staining (AFB) for rapid detection of Mycobacterium tuberculosis in specimen of patients suspected of pulmonary tuberculosis (PTB) and extra pulmonary tuberculosis (EPTB). Methods: A comparative cross-sectional study of 400 samples (PTB-365 and EPTB-35) of patients visiting National Tuberculosis Centre (NTC) was conducted from July 2018 to December 2018. Gene Xpert MTB/ RIF Assay, smear microscopy were performed under standard guideline inside biosafety cabinet class II. The result obtained from both the tests were analyzed using SPSS 20.0 software and Excel 2019. Results: Of the total samples, 18% (72/400) and 39% (156/400) were positive by AFB smear microscopy and Xpert MTB/RIF assay respectively. Prevalence of MTB positive was highest in the age group 35-44 years, 33 cases (17.74%) were detected in total, with a male to female ratio of 2.3:1. Pleural fluid, pus, and CSF fluid also yielded positive results with the Gene Xpert MTB/RIF assay accounting 1.28%, 0.64% and 1.28% of MTB positive case respectively. Rifampicin resistance was observed in 1.28% of the cases. Conclusion: The key findings of this study suggest that Gene Xpert test should be implemented as primary diagnostic test for PTB and EPTB.

scholarly journals Pattern of Skin Diseases: Experience from a Rural Community of Bangladesh

2014 ◽  
Vol 41 (1) ◽  
pp. 50-52
Author(s):  
N Ahmed ◽  
MZ Islam ◽  
S Farjana
Keyword(s):  
Rural Community ◽  
Skin Diseases ◽  
Ecological Factors ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Cutaneous Infections ◽  
The People ◽  
Disease Pattern ◽  
Male To Female

Disease pattern in a given population is generally determined by different ecological factors. Thus the objective of this cross-sectional study was to determine the pattern of skin diseases in a selected rural community of Dhamrai Upazila under Dhaka district. Out of 2645 patients attending a medical camp showed 410(15.5%) patients with dermatological problems. Among all, 260(63.4%) patients were males and 150(36.6%) were females with a male to female ratio of 1.7:1. Of these patients, 178(43.4%) had cutaneous infections and 234(56.6%) had non-infectious dermatoses. Few patients (2.7%) had more than one dermatoses. Fungal infection was the commonest infection seen (22.9%) and eczemas took an upper hand in non-infectious group (32.2%). Improvement in the standard of living, health education, improvement in the environmental sanitation and good nutritious food may help the people to bring down the skin disease in the rural part of country. DOI: http://dx.doi.org/10.3329/bmj.v41i1.18784 Bangladesh Medical Journal 2012 Vol. 41 No. 1; 50-52

Additional cytogenetic abnormalities in chronic myeloid leukemia; an experience from Pakistan

2020 ◽  
pp. 1-8
Author(s):  
Nida Anwar ◽  
Muhammad Nadeem ◽  
Sana Khurram ◽  
Naveena Fatima ◽  
Tahir Shamsi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
International System ◽  
Marrow Transplant ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Cytogenetic Abnormalities ◽  
Human Cytogenetic ◽  
Bone Marrow Cultures ◽  
Male To Female

Abstract Objectives: To evaluate the presence and characteristics of additional karyotype abnormalities in chronic myeloid leukaemia cases. Method: The cross-sectional study was conducted at the Department of Cytogenetics and Molecular Pathology, National Institute of Blood Diseases and Bone Marrow Transplant, Karachi, from May 2010 to September 2016 and comprised diagnosed chronic myeloid leukaemiapatients regardless of age and gender.Baseline cytogenetic evaluation was done on overnight, 24-hrs un-stimulated and 72-hrs stimulated bone marrow cultures, and karyotypes were defined according to the International System for Human Cytogenetic Nomenclature2013. Data was analysed using SPSS 23. Results: There were 222 cases with a median age of 38 years (range: 12-84 years). The male-to-female ratio was 1.8:1. Chronic myeloid leukaemiawas detected in 18(8.1%) patients havingadditional cytogenetic abnormalities. Among the patients found positive, cytogenetic type was minor in 10(55.55%), major 3(16.66%), complex 3(16.66%), and variant 2(11.11%). . Conclusion: Additional cytogenetic abnormalitieswere found in 8% of the sample. Key Words: Additional cytogenetic abnormalities, Chronic myelogenous leukaemia, Bone marrow, Cytogenetics.

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