Autoimmunity and Antibody Dependent COVID-19 Enhancement of SARS CoV-2 Vaccination: Moving from Nobel Prize to Prison Sentence.
mRNA based and adenovirus vectored vaccines, types of nucleic acid-based vaccination, were first ever or first commercially ever approved for the public, respectively. However, these new types possess a potential risk to induce auto-immune diseases e.g. thrombocytopenia and some of these complications might also reason for some of the post vaccination sudden death reports e.g. autoimmune myocarditis and immune induced thromboembolism. Moreover, all SARS CoV-2 types of vaccines, depending on the spike protein immunogenicity, especially the conventional inactivated ones might increase the likelihood of COVID-19 severity upon re-infection through antibody dependent enhancement which might also reason for some of the serious adverse effects encountered with administration of convalescent plasma to COVID-19 patients. Importantly, we recommended the CDC to change its neutral recommendation and to advice against administration of nucleic acid-based vaccines to persons complaining from autoimmune diseases. Furthermore, we urge the FDA to consider a reevaluation of the emergency approval granted to Pfizer-BioNTech SARS CoV-2 mRNA (BNT162b2) vaccine as a company specific extra risk might be present wishing for an independent re-evaluation of the important Israeli pan-national experiment. On the other hand, we agree with the EMA decision to reevaluate the safety of Oxford/AstraZeneca (AZD1222) vaccine that ultimately led to a potential thrombosis labelling. Most importantly, a moral, legal, and sacred constitutional public right to know and decide basing on a personalized risk benefit ratio must be secured. Finally, we totally condemn, from a medical point of view, any national policy that necessitates these experimental vaccines and we also condemn the European Court of Human Rights shameful ruling that compulsory vaccination would not contravene human rights law and we suggest that the rapid race to develop and approve SARS CoV-2 vaccines with all its political and economic aspects might eventually end with a man-made Hades that might exceed COVID-19 in its dangers with a potential to replace Nobel Prize with an imprisonment sentence regardless of the signed agreements that will not, ever, secure impunity.