scholarly journals CERTAIN FLAVONOIDS IN THE PLANT HYPERICUM PERFORATUM L. AND THEIR EFFECTS ON HUMAN HEALTH

2021 ◽  
Author(s):  
EditorJournals and Conferences

This article provides detailed information on the morpho-physiological characteristics, chemical composition, especially the amount of flavonoids and their function in the body and their role in human health, as one of the medicinal plants Hypericum Perforatum L.At the beginning of the article we will discuss in detail the role and distribution of the plant Hypericum Perforatum L. in modern taxonomy. The article describes the properties of rutin flavonoid, one of the most common flavonoids in this plant, and its biochemical functions in plants and humans.

2022 ◽  
Author(s):  
EditorJournals and Conferences

This article provides information on the morpho-physiological characteristics, chemical composition, especially the amount of alkaloids and vitamins, and their function in the body, as well as thorn bushes, hole field, yarrow plants, which are considered medicinal plants.The article deals with the botanical and morpho-physiological characteristics of the plant Achillea Millefolium L., one of the medicinal plants used in scientific medicine, systematics, some biologically active substances in the chemical composition, especially vitamins and alkaloids, their function in the body and their role in human health. details are given.The following article describes the role of Capparis spinosa L. in modern taxonomy, its distribution, the structure and properties of the most common alkaloids and vitamins in the plant, and its biochemical functions in the human body.The article concludes with a detailed description of the morpho-physiological characteristics of the plant Hypericum Perforatum L., its chemical composition, especially the amount of alkaloids and vitamins and their function in the body and their role in human health.


2022 ◽  
Author(s):  
EditorJournals and Conferences

This article provides detailed information on the morpho-physiological characteristics, chemical composition, especially the amount of alkaloids and their function in the body and their role in human health, as one of the medicinal plants Hypericum Perforatum L.


2005 ◽  
Vol 19 (3) ◽  
pp. 295-303 ◽  
Author(s):  
F. Conforti ◽  
G.A. Statti ◽  
R. Tundis ◽  
A. Bianchi ◽  
C. Agrimonti ◽  
...  

2021 ◽  
pp. 57-63
Author(s):  
И.Ю. Постраш

Трава зверобоя является ценным лекарственным растением, так как содержит большое число разнообразных биологически активных соединений, важнейшими из которых являются флавоноиды (1,5–5%), нафтодиантроны, дубильные вещества (10–13%), эфирное масло (0,1–0,33%) и др. Препараты, содержащие зверобой, комплексно воздействуют на организм, они оказывают противовоспалительное, антимикробное, антидепрессивное, противовирусное, кровоостанавливающее действие. Трава зверобоя применяется в виде чаёв, отваров, водных настоев, спиртовых и масляных настоек, мазей, сухих экстрактов. В ветеринарной медицине широко применяют настои и отвары травы зверобоя при заболеваниях ЖКТ: диспепсиях, гастроэнтеритах, острых и хронических колитах (КРС, овцы, козы, свиньи, собаки и др.), а также при лечении смешанных инвазий. Настои и настойку применяют также наружно при стоматитах, гингивитах, фарингитах. Несмотря на перечисленный выше ассортимент лекарственных форм зверобоя, активно ведутся научные исследования по оптимизации способов извлечения биологически активных веществ (БАВ) из травы зверобоя продырявленного. В ходе экспериментов исследователи варьируют различные параметры процесса экстракции: химический состав экстрагентов (монофазная и двухфазная экстракция), время и температуру экстракционного процесса, количественное соотношение сырья и экстрагентов, степень измельчения сырья, последовательность технологических операций, возможность применения излучения и др. Разработки новых ресурсосберегающих технологий переработки зверобоя продырявленного будут способствовать снижению себестоимости фармацевтической продукции и улучшению её фармакологических свойств. Hypericum perforatum grass is a valuable medicinal plant, since it contains a large number of various biologically active compounds, the most important of which are flavonoids (1.5–5%), naphthodianthrones, tannins (10–13%), aethereal oil (0.1–0.33%), etc. Preparations containing Hypericum perforatum have a complex effect on the body, they have an anti-inflammatory, antimicrobial, antidepressant, antiviral, hemostatic effect. Hypericum perforatum grass is used in the form of teas, apozems, water infusions, alcohol and oil tinctures, ointments, dry extracts. In veterinary medicine, infusions and decoctions of Hypericum perforatum grass are widely used in diseases of the gastrointestinal tract: dyspeptic disorder, gastroenteritis, acute and chronic colitis (cattle, sheep, goats, pigs, dogs, etc.), as well as in the treatment of mixed invasions. Infusions and tincture are also used externally for stomatitis, gingivitis, blennisthmia. Despite the above range of dosage forms of Hypericum perforatum, researches are actively conducted to optimize methods of extracting biologically active substances (BAS) from Hypericum perforatum grass. During the experiments, researchers vary various parameters of the extraction process: the chemical composition of extragents (monophasic and two-phase extraction), the time and temperature of the extractive process, the quantitative relation of raw materials to extragents, the dispersity of raw materials, the sequence of technological operations, the possibility of using radiation, etc. The development of new resource-saving technologies for processing Hypericum perforatum will help reduce the cost of pharmaceutical products and improve its pharmacological properties.


2019 ◽  
Vol 55 (4) ◽  
pp. 392-402 ◽  
Author(s):  
XuXu Yang ◽  
Elena Popova ◽  
Mukund R. Shukla ◽  
Praveen K. Saxena

Author(s):  
O. I. Lisovets ◽  
I. S. Serchenko

In the course of research conducted in the laboratory of radioecology of DNU, information was obtained on the beta-radioactivity of nine species of medicinal plants from two types of habitats – meadow biocenosis on the outskirts of the village. Kirovsky Dnipro region and a weed-meadow group near the town of Kamyanske, Dnipro area. Beta-radioactivity of the studied medicinal plants varied in the range from 1.18×10-5 Bq to 19.09×10-5 Bq at relatively clean habitats and from 18.35×10-5 Bq to 82.95×10-5 Bq on the anthropogenically polluted area. In a relatively clean habitat, the lowest indicators of beta-radioactivity in aboveground organs are characterized by Artemisia vulgaris L. and Capsella bursa-pastoris (L.) Medikus, the highest – Hypericum perforatum L. and Achillea submillefolium Klokov & Krytzka. In the underground organs, the highest indicators of beta-radioactivity were recorded in Artemisia vulgaris and Hypericum perforatum, the lowest – in Melissa officinalis L. and Valeriana officinalis L. Under conditions of industrial pollution, the lowest indicators of beta-radioactivity in aboveground organs were found in Artemisia vulgaris and Matricaria recutita L., in underground – in Tanacetum vulgare L. and Achillea submillefolium. The highest values of beta-radioactivity in these conditions were registered in the aboveground organs of Tanacetum vulgare and Hypericum perforatum and in the underground parts of  Melissa officinalis and Hypericum perforatum. The analysis showed that the anthropogenic factor (pollution) has a statistically proven effect on the beta-radioactivity of the studied medicinal plants (with a probability of P = 0.999). Indicators of the strength of influence were high – from 67 to 85%. Anthropogenic pollution has the greatest impact on the beta-radioactivity of underground organs. The identified trend reflects a well-known natural dependence – the farther along the transport chain from the root is the body, the less, as a rule, it accumulates radionuclides. The detected values of beta-radioactivity, including in the industrially contaminated area are not dangerous with a single use of the studied medicinal plants. However, medicinal plants collected in the contaminated area due to increased beta-radioactivity can cause damage with prolonged systematic use due to the cumulative effect and are therefore not recommended for use.


2011 ◽  
Vol 68 (11) ◽  
pp. 930-934 ◽  
Author(s):  
Danijela Djukic-Cosic ◽  
Aleksandra Stanojevic ◽  
Marija Djekic-Ivankovic ◽  
Marijana Curcic ◽  
Zorica Plamenac-Bulat ◽  
...  

Background/Aim. The beneficial effects of medicinal plants are well-known from the ancient times. However, expansion of phytopharmacy and phytotherapy occured during the last decades. Medicinal plants can absorb environmental contaminants from the ground and consequently may cause harmful effects on human health. Quality control usually comprises standard methodology which includes macroscopic identification and examination of active ingredients. Additionaly, there is a permanent need to control the level of pollutants in herbs, with a particular attention to the level of toxic metals. In this study we estimated the level of contamination by determining the content of cadmium (Cd) in the herbs of Hypericum perforatum and Thymus serpyllum collected from the different localities of the mountains Rtanj and Ozren. Methods. Herbs of investigated plants were collected during July 2005 from various localities of Rtanj and Ozren mountains. After drying, homogenization and mineralization, Cd content was determined by atomic absorption spectrophotometry. Results. The obtained results show that Cd content varies significantly in Hypericum perforatum samples collected. The lowest Cd level was found in samples from the one of Rtanj localities (0.25 mg Cd/kg), while the highest was observed in Hypericum perforatum from Ozren locality (1.24 mg/kg). Levels of Cd in the three of four investigated localities were higher than pro posed by WHO (0.3 mg/kg dried herb material). In all investigated samples of Thymus serpyllum herbs Cd levels were below the limit of detection of analytical method (0.2 mg Cd/kg dried materials). Conclusion. This work contributes to the issue of Cd content in Hypericum perforatum and Thymus serpyllum grown in localities of Rtanj and Ozren, and implies the importance for systemic control of Cd content in Hypericum species in order to provide safety of their preparations. Furthermore, regarding Cd toxicity, maximal permissible level of Cd in plant material should be evaluated and established concerning national legislative frame.


Author(s):  
Surabhi Shakya ◽  
Padmini Shukla ◽  
Prabodh Shukla

Herbal immunity boosters are the medicinal plants which increase the immunity of the human body and make the body able to fight with the various diseases. These immunity boosters are serving as a boon in the case of coronavirus disease. COVID-19 affects our respiratory system and lowers the immunity of the patient and the persons having weak immunity have the more chances to get affected with the diseases. Tulsi, garlic, ginger, giloy, coconut oil, turmeric, ashwagandha, amla, black pepper, aloevera are the herbal immunity boosters. These herbal drugs used traditionally in medicines and also proved effective in scientific studies.  The regular consumption of these boosters helps to treat the mild to moderate symptoms of diseases at home. Keywords: Herbal immunity boosters, Coronavirus, COVID-19, Garlic, Tulsi, Ginger, Aloe vera


2020 ◽  
Vol 86 (8) ◽  
pp. 12-22
Author(s):  
V. A. Volkov ◽  
M. V. Voronkov ◽  
V. M. Misin ◽  
E. S. Fedorova ◽  
I. A. Rodin ◽  
...  

Water-propylene glycol extracts of medicinal plants are widely used as active components in therapeutic and cosmetic products for external use. However, sparse data on the extracting efficiency of water-propylene glycol mixtures and chemical composition of water-propylene glycol extracts of plant raw materials are available in the scientific literature. Usually the manufacturer documentation also provides information about characteristics of the products that are not related to their biological activity. The results of HPLC/MS/MS study of Matricaria chamomilla L. flowers have shown that water-propylene glycol and water-ethanol extracts are similar in the composition of phenolic compounds: the dominant compounds of water-propylene glycol extract of Matricaria chamomilla L. flowers are apigenin and its glycosides (apigenin-7-glucoside, apigenin-7-O-6-O-malonyl-D-glycoside, apigenin-7-acetylglycoside, acetyl-malonyl-apigenin-7-O-glycoside), as well as 5,4’-dioxy-3,6,7,3’-tetramethoxyflavone, cis- and trans-forms of 2-O-glucopyranoside 2-hydroxy-4-methoxycoric acid, 7-methoxycumarin. Spectral and analytical characteristics in the UV-visible range of the spectra of water-propylene glycol extracts of a number of medicinal plants most often used in the cosmetic industry were studied to reveal extracts with the highest protective properties against UV radiation in A and B areas (extracts of Salvia officinalis L. leaves, Matricaria chamomilla L. flowers, Achillea millefolium L. grass), free radicals (extracts of Camellia sinensis L. leaves, Hypericum perforatum L. herb), and the highest content of flavonoids (extracts of Hypericum perforatum L. herb, leaves of Salvia officinalis L.) were revealed. When extracting raw materials from the same batch, the optical density at a wavelength of 270 nm is associated with the content of flavonoids, antioxidants and dry matter by a functional relationship, which is very convenient for rapid control of extraction processes in order to obtain a product with reproducible characteristics. Formulas for calculating the content of antioxidants in extracts using the DPPH method in comparison with standard samples of rutin and gallic acid are derived. Interpretation of data on the antioxidant content in different extracts in comparison with other analytical parameters are also presented. Demonstrated high repeatability of the shape of the spectral curves of Matricaria chamomilla L. flowers extract, observed regardless of the source of raw materials can be used in combination with the individuality of the curve shape of the extracts of raw materials of different types as one of the authenticity criteria. The proposed UV-spectrometric method was used to study the dynamics of Matricaria chamomilla L. flower extraction under different process parameters (temperature, propylene glycol/water ratio in the extractant). It is shown that extraction of raw materials with 50% water-propylene glycol for 4 h at a temperature of 50°C is optimal.


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