scholarly journals Hypericum Perforatum Grass: Chemical Composition, Properties, Use

2021 ◽  
pp. 57-63
Author(s):  
И.Ю. Постраш

Трава зверобоя является ценным лекарственным растением, так как содержит большое число разнообразных биологически активных соединений, важнейшими из которых являются флавоноиды (1,5–5%), нафтодиантроны, дубильные вещества (10–13%), эфирное масло (0,1–0,33%) и др. Препараты, содержащие зверобой, комплексно воздействуют на организм, они оказывают противовоспалительное, антимикробное, антидепрессивное, противовирусное, кровоостанавливающее действие. Трава зверобоя применяется в виде чаёв, отваров, водных настоев, спиртовых и масляных настоек, мазей, сухих экстрактов. В ветеринарной медицине широко применяют настои и отвары травы зверобоя при заболеваниях ЖКТ: диспепсиях, гастроэнтеритах, острых и хронических колитах (КРС, овцы, козы, свиньи, собаки и др.), а также при лечении смешанных инвазий. Настои и настойку применяют также наружно при стоматитах, гингивитах, фарингитах. Несмотря на перечисленный выше ассортимент лекарственных форм зверобоя, активно ведутся научные исследования по оптимизации способов извлечения биологически активных веществ (БАВ) из травы зверобоя продырявленного. В ходе экспериментов исследователи варьируют различные параметры процесса экстракции: химический состав экстрагентов (монофазная и двухфазная экстракция), время и температуру экстракционного процесса, количественное соотношение сырья и экстрагентов, степень измельчения сырья, последовательность технологических операций, возможность применения излучения и др. Разработки новых ресурсосберегающих технологий переработки зверобоя продырявленного будут способствовать снижению себестоимости фармацевтической продукции и улучшению её фармакологических свойств. Hypericum perforatum grass is a valuable medicinal plant, since it contains a large number of various biologically active compounds, the most important of which are flavonoids (1.5–5%), naphthodianthrones, tannins (10–13%), aethereal oil (0.1–0.33%), etc. Preparations containing Hypericum perforatum have a complex effect on the body, they have an anti-inflammatory, antimicrobial, antidepressant, antiviral, hemostatic effect. Hypericum perforatum grass is used in the form of teas, apozems, water infusions, alcohol and oil tinctures, ointments, dry extracts. In veterinary medicine, infusions and decoctions of Hypericum perforatum grass are widely used in diseases of the gastrointestinal tract: dyspeptic disorder, gastroenteritis, acute and chronic colitis (cattle, sheep, goats, pigs, dogs, etc.), as well as in the treatment of mixed invasions. Infusions and tincture are also used externally for stomatitis, gingivitis, blennisthmia. Despite the above range of dosage forms of Hypericum perforatum, researches are actively conducted to optimize methods of extracting biologically active substances (BAS) from Hypericum perforatum grass. During the experiments, researchers vary various parameters of the extraction process: the chemical composition of extragents (monophasic and two-phase extraction), the time and temperature of the extractive process, the quantitative relation of raw materials to extragents, the dispersity of raw materials, the sequence of technological operations, the possibility of using radiation, etc. The development of new resource-saving technologies for processing Hypericum perforatum will help reduce the cost of pharmaceutical products and improve its pharmacological properties.

2022 ◽  
Author(s):  
EditorJournals and Conferences

This article provides information on the morpho-physiological characteristics, chemical composition, especially the amount of alkaloids and vitamins, and their function in the body, as well as thorn bushes, hole field, yarrow plants, which are considered medicinal plants.The article deals with the botanical and morpho-physiological characteristics of the plant Achillea Millefolium L., one of the medicinal plants used in scientific medicine, systematics, some biologically active substances in the chemical composition, especially vitamins and alkaloids, their function in the body and their role in human health. details are given.The following article describes the role of Capparis spinosa L. in modern taxonomy, its distribution, the structure and properties of the most common alkaloids and vitamins in the plant, and its biochemical functions in the human body.The article concludes with a detailed description of the morpho-physiological characteristics of the plant Hypericum Perforatum L., its chemical composition, especially the amount of alkaloids and vitamins and their function in the body and their role in human health.


Author(s):  
SHAPOVALOVA Nataliia ◽  
VEZHLIVTSEVA Svitlana ◽  
ANTIUSHKO Dmytro

Background. The deficiency of essential nutrients in the human body is the root cause of reduced efficiency, general resistance of the body to various diseases. That is an urgent problem in the context of the spread of coronavirus infection. In this regard, the search for opportunities to meet the needs of the population in food products that contain biologically active substances (BAS) through the use of high-value and at the same time available plant raw materials is extremely important. Marigolds attract special attention among such raw materials. The aim of the work is to study the chemical composition and evaluate the consumer properties of Tagetes L. varieties, zoned in the Kiev region, to prove the possibility of increasing the biological value of pasta by adding to their recipe powder from marigold inflorescences. Materials and methods. The object of research is pasta of B group (noodles). Inflorescences of marigolds of different varieties gathered during the flowering period in July-September 2019–2020 in the territory of Vasylkiv and Obukhiv districts of Kyiv region, Ukraine were used as enriching plant raw materials. The quality of finished pasta was assessed by organoleptic and physicochemical indexes (moisture content and titratable acidity). The content of mineral elements in the fine powder of marigold inflorescences was determined on the EXHERT-3L device, the quantitative composition and BAS identification – by spectrophotometric analysis on the device Specord-200 Analytic Jena UV-vis. The integrated quality index of pasta products was calculated taking into account the importance factors of individual indexes. Results. Comparing the obtained results, we can state that all the studied varieties – Gold Kopfen, Orange Flame, Hawaii, Equinox are characterized by high biological value, regardless of the area of collection. As a result of calculated and experimental studies it was determined that the addition of 7 % of the supplement does not provide the required supply of vitamins and minerals. Replacing the flour in the recipe by 20 % significantly improves the mineral composition, but deteriorates the taste and aromatic properties of pasta. The most optimal and rational amount of added additive is 15 %, as it improves the organoleptic properties of pasta and enriches their BAS. Conclusion. The usage of non-traditional vegetable raw materials, in particular powder from marigold inflorescences, which is rich in biologically active substances, allows not only to expand the range, improve the quality of finished products, but also increase the biological value of the product. The optimal amount of additive –powder from marigold inflorescences, was defined. It is 15 % by weight of flour in the production of noodles. This concentration allows not only to improve the organoleptic properties, but also to increase the content of biologically active substances – vitamins, micro- and macronutrients. The usage of non-traditional natural raw materials (powder from marigold inflorescences) allows to abandon artificial colorsand give the finished pasta a pleasant colorand aroma.


2021 ◽  
Vol 941 (1) ◽  
pp. 012023
Author(s):  
O P Chzhu ◽  
D E Araviashvili ◽  
A L Tumanova

Abstract The selection of the Black Sea aquatic area as a hydrobiont biologically active compound source allows resolving several environmental problems including development of an integrated hydrobiological resource management system for the Black Sea as a new sector of modern pharmacology. Aquatic organisms produce unique secondary metabolites. This paper presents the results of studies on the development of the biologically active substance extraction technology from non-commercial aquatic organisms as well as a preliminary assessment of the biochemical activity of the substrates obtained. Biologically active substances were extracted using the of two-phase extraction method in conjunction with ultrasound. For the substrates, the antioxidant activity was determined utilising the method that allow conducting screening of pharmaceutical raw materials and biologically active substances with high antioxidant activity. The protective activity evaluation was carried out during the study of the enzymatic alcoholic fermentation kinetics within a self-contained system. The evaluation of lymphocytes proliferative activities influenced by the obtained substrates was carried out using the cultivation method. The acquired data allows recommending the two-phase extraction method combined with ultrasonic voiceover as the effective one when processing analogical marine raw materials. The isolated substrates are characterised by a pronounced biochemical activity in relation to the living systems cells, which suggests a significant synergistic effect with derivatives of the microalgae Chlorella Vulgaris.


Author(s):  
Т.В. ПЕЛИПЕНКО

Исследованы потенциальные возможности ресурсосберегающей технологии переработки шалфея лекарственного (ШЛ). Объектом исследования были образцы эфирномасличного сырья – свежеубранные надземные части ШЛ в фазе полного цветения растения и сухие листья ШЛ. Предложенная схема переработки включает следующие стадии: получение эфирного масла; извлечение конкрета из обезэфиренных отходов экстракцией углеводородным растворителем и последующей его отгонкой; получение абсолютного масла и очищенных восков из конкрета отходов; извлечение дитерпеновых соединений экстракцией этиловым спиртом из отходов сырья после обработки гексаном. В результате исследований фракционного состава сырья и особенностей локализации эфирного масла установлено, что массовая доля эфирного масла составляет, % к сухой массе исследуемых фракций: в листьях и соцветиях 2,75, в стеблях 0,31. Рекомендовано введение ограничительных норм по соотношению технически ценной фракции – листьев и соцветий и балластной – стеблей. Полученное из ШЛ эфирное масло имеет высокое содержание туйонов (31,50%), камфоры (21,0%) и 1,8-цинеола (18,80%). Выход дитерпеновых соединений при комплексной переработке эфирномасличного сырья ШЛ на 38,0% ниже, чем из сухих листьев растения. Однако при расчете на сухую массу листьев и соцветий, составляющих 62,3% от массы сырья, показатели отличаются незначительно. Общий выход продуктов, содержащих комплекс биологически активных веществ, составил 15,53 %, что подтверждает целесообразность использования комплексной переработки шалфея лекарственного. The potential of resource-saving technology for processing medicinal sage (MS) has been studied. Samples of essential oil raw materials-freshly harvested aboveground parts of MS in the phase of full flowering of the plant and dry leaves of MS were the object of research. The proposed process flow diagram includes the following stages: obtaining essential oil; recovering a particular from deester waste by extraction with a hydrocarbon solvent and its subsequent distillation; obtaining absolute oil and refined waxes from a specific waste; extraction of diterpene compounds from raw waste after treatment with hexane by extraction with ethyl alcohol. As a result of studies of the fractional composition of raw materials and the features of localization of essential oil, it was found that the mass fraction of essential oil is, % of the dry mass of the studied fractions: 2,75 in leaves and inflorescences, and 0,31 in stems. The introduction of restrictive norms on the ratio of technically valuable fraction – leaves and inflorescences and ballast – stems is recommended. The essential oil obtained from MS has a high content of tuyons (31,50%), camphor (21,0%) and 1,8-cineol (18,80%). The yield of diterpene compounds in the complex processing of essential oil raw materials MS is 38,0% lower than from dry leaves of the plant. However when calculating the dry mass of leaves and inflorescences, which make up 62,3% of the mass of raw materials, the indicators differ slightly. The total yield products containing a complex of biologically active substances amounted to 15,53%, which confirms the feasibility of complex processing of medicinal sage.


2020 ◽  
Vol 15 (4) ◽  
pp. 535-543
Author(s):  
A.L. Alekseev ◽  
◽  
T.V. Alekseeva ◽  

The article presents the research results obtained during the development of the technology for production of combined sausages using a vegetable-derived additive – LUPISAN lupine flour from “OOO Protein PLUS” (St. Petersburg). Under the conditions of a deteriorating environmental situation and the increase in incidence of the population of the Russian Federation, it became necessary to create biologically complete functional food products with additional functions, useful nutritional and physiological characteristics, based on the integrated use of raw materials of animal and vegetable origin. The use of plant materials in the production of meat products allows not only enriching them with functional ingredients and increasing digestibility, but also obtaining products that meet physiological nutritional standards. Having a complex chemical composition, plants have a beneficial therapeutic effect on the human body. Research was carried out at the Department of Food Technology of the Don State Agrarian University, in the testing laboratory of the Shakhty branch of the Rostov “SBBZh” and at the meat processing plant “TaVr-Zimovniki”. Basing on the conducted comprehensive studies, the effectiveness of using vegetable protein supplement based on lupine flour “LUPISAN” in the production technology of semi-smoked sausages is substantiated. It is established that in terms of quality and safety, LUPISAN meets the requirements for additives of plant origin, it is a genetically unmodified, kosher product (has the appropriate certificates). It is dispersible both in oil and in water and can be used as a natural emulsifier without labeling with the index "E". The analysis of the chemical composition and nutritional value of flour from lupine indicates that the flour contains a significant amount of complete protein is 36–40%; in addition, a rather high content of dietary fiber is noted: dietary fiber is 30–35%. It is a strong antioxidant, it does not contain gluten and cholesterol; there are no inhibitors – substances that delay the digestion process and inhibit the absorption of beneficial substances by the body, and there are glycoproteins – substances that can replace insulin. An optimal dose of introducing a protein supplement based on lupine flour into sausage stuffing is proposed, which is 10% by weight of unsalted raw materials, which makes it possible to obtain a finished product with high organoleptic quality indicators and functional properties.


2021 ◽  
pp. 85-92
Author(s):  
Natal'ya Yur'yevna Adamtsevich ◽  
Elena Vladimirovna Feskova ◽  
Valeriy Stanislavovich Boltovsky ◽  
Vladimir Vladimirovich Titok

One of the possible ways to intensify and increase the efficiency of extraction of biologically active substances from plant materials is the use of microwave radiation. This article presents the results of a study of the influence of parameters of the microwave extraction process on the output of flavonoids from the leaves of the littlewale (Lithospermum officinale L.), belonging to the Boraginaceae family. This plant contains isoquercitrin, which is one of the key flavonoids with the property of tissue regeneration. It was shown that the maximum yield of the target components is achieved with a microwave generator power of 100 W and exposure duration of 2.5 min at a field frequency of 2450 MHz (specific energy consumption is 8.4 kWh/kg). This output is comparable with the output when using conventional convection heating. Microwave radiation provides a 16-fold reduction in the duration of extraction of the sum of flavonoids and an increase in the degree of extraction of isoquercitrin by 23%. The action of microwave energy leads to the destruction of plant tissue, which contributes to a more efficient extraction of flavonoids from plant raw materials.


2021 ◽  
Vol 3 (3(59)) ◽  
pp. 46-49
Author(s):  
Kateryna Kasabova ◽  
Nataliа Shmatchenko ◽  
Aleksey Zagorulko ◽  
Andreii Zahorulko

The object of research in this work is the technology of pastille with the addition of multicomponent fruit and berry paste. Pastille are becoming more and more popular in the world for all segments of the population. Usually, the main ingredients for their manufacture are fruit raw materials, a structurant and egg white, therefore, the products contain practically no fat and have a low calorie content. It is proposed to replace 75 % of traditional applesauce in the recipe with a multicomponent fruit and berry paste made from apples, cranberries, hawthorn. It was found that such a composition makes it possible to obtain products with an increased content of pectin substances, ascorbic acid, polyphenols, including anthocyanins, catechins and flavonols. The work is aimed at studying the application of the principles of qualimetry to determine a complex indicator of the quality of pastille For this, the organoleptic and physicochemical indicators of the quality of the developed pastille were taken from previous studies and the chemical composition was determined and the content of biologically active substances was calculated relative to the average daily human need. The content of pectin substances in new products increases 1.7 times and satisfies the average daily human need by 18.2 %. The content of ascorbic acid is 4.2 times higher, which is 20.5 % of the average daily human need, and polyphenols 3.2 times higher – 579.0 %. The data obtained make it possible to consider the developed product functional. The next step was to determine the complex indicator of products by the qualimetric method. For a more complete disclosure of product properties, a structure of pastille quality indicators has been developed – a «tree of properties». Thus, the comprehensive assessment of the quality of the control sample corresponds to the indicator «good» (0.66), while the integrated assessment of pastille with multicomponent paste corresponds to the indicator «very good» (0.98). On the basis of organoleptic, physicochemical indicators and chemical composition of products, it was established that the indicator of a comprehensive assessment of the quality of a pastille with a multicomponent paste, taking into account all group indicators, is 48 % higher compared to the control.


2020 ◽  
pp. 66-72
Author(s):  
Viktoriya Pogarskaya ◽  
Raisa Pavlyuk ◽  
Tatyana Kotuyk ◽  
Olga Yurieva ◽  
Nadiya Maksymova

The aim of research is to develop a new method for the production of protein plant nanoadditives from dry chickpea in the form of nanopowders and nanopastes using the processes of steam thermo-mechanical destruction, leading to a high degree of mechanical destruction of biopolymers in separate constituent monomers, without destroying the latter. The new method is based on the use as an innovation of a complex effect on raw materials of steam-thermal treatment in modern steam-thermal devices (at a temperature of +70 °C) and non-enzymatic catalysis, which occurs when using fine grinding. The proposed method makes it possible to more fully reveal the biological potential of plant raw materials and transform hardly soluble, indigestible by the human body components of raw materials (in particular, cellulose, pectin substances, proteins and their nanocomplex and nanoassociates) into components that are easily absorbed by the body. The method makes it possible to more completely remove from the raw materials inactive bound forms of individual monomers of biopolymers, to reduce the molecular weight of biopolymers. At the same time, the efficiency of the resulting product increases significantly when consumed by the human body. New additives from chickpea are fundamentally different from traditional ones in properties and physicochemical state. The developed additives act simultaneously five in one: a source of essential amino acids and other biologically active substances, structure formers, gelling agents, thickeners and yellow dyes. The obtained protein supplements from chickpeas in combination with herbal Nanoadditives (from pumpkin, carrots, lemons, garlic, celery roots, ginger) were used as recipe components in the development of a new generation of confectionery products. The resulting confectionery products differ from the traditional ones in their low sugar and fat content (up to 5 %), high content of complete protein (from 13 to 20 %). In addition, 100 g of new products are able to satisfy the daily requirement for biologically active substances (β-carotene, phenolic compounds) and 0.5 daily requirement for vitamin C. The resulting products are natural, do not contain harmful impurities and exceed the quality of world analogues


2020 ◽  
pp. 35-46
Author(s):  
Konstantin Grigor'yevich Bogolitsin ◽  
Anastasiya Eduardovna Parshina ◽  
Anna Sergeyevna Druzhinina ◽  
Elena Valer'yevna Shulgina

Brown algae are a valuable source of a variety of biologically active compounds. Their accumulation is influenced by many environmental factors in which macrophytes grow. The purpose of this study is to carry out comparative studies of the general chemical composition of brown algae in the White and Yellow Seas to substantiate the possibility of their use as raw materials for obtaining new pharmaceutical substances. Using the proposed scheme, which involves sequential supercritical fluid, acid, alkaline and water extraction, it was possible to isolate various components of brown algae, including a protein-polysaccharide complex, which in the case of the species Laminaria digitata and Laminaria saccharina is more than 80% cellulose and squirrel. The data obtained by FTIR spectroscopy confirm the qualitative composition of the complexes and also indicate its purity. Significant differences were revealed in the chemical elemental and component composition, which are affected by the growing conditions of macrophytes. The resulting chemical compounds from brown algae biomass, in particular the protein-polysaccharide complex, have a high potential for obtaining new pharmacological preparations based on them for health protection purposes. Based on the previously obtained data, it can be assumed that this complex has a double activity – enterosorption and immunomodulatory.


Author(s):  
Kateryna Slobodianiuk ◽  
◽  
Kateryna Samoilenko ◽  

The article presents a reasonable analysis and relevance of the study of the drying process of vegetable raw materials (colloidal capillary-porous materials). Drying is an energy-intensive industrial process that is defined from a technological point of view: on the one hand by heat and moisture exchange between the body surface and the environment, on the other hand by heating the body and transferring moisture inside it due to the form of moisture. One of the most effective ways to increase the shelf life of food is to dry it to equilibrium humidity. Very important are the technological parameters of the drying regimes, which, when used rationally, are able to preserve the biochemical properties and nutrients of the raw material at a high level in the obtained dry product. The study of dehydration of vegetable raw materials is widely practiced around the world, especially in countries such as Germany, France, USA, Argentina, Hungary, Brazil, Poland, Korea, China, Malaysia. However, the obtained processed products lose their biologically active components and nutrients, and the processing process is energy consuming. Therefore, the problem is relevant and needs an effective solution. In this paper, the kinetics of the drying process, thermogravimetric studies and a mathematical model for colloidal capillary-porous materials of plant origin were analyzed. According to the results of the highlighted research, the process of convective drying of colloidal capillary-porous materials was intensified above 21% due to the use of innovative step regimes. The developed beet-rhubarb composition is a colloidal capillary-porous material that stabilizes and protects at the biochemical level betanin of the beet from the effects of temperature during convective drying, has in comparison with the components of the composition lower heat of dehydration and increased thermal-stability. Prolonged high-temperature exposure causes instant complete destruction of sugars, proteins and other nutrients components. Derivatographic studies have confirmed that the use of the temperature range of 100 ° C in a stepwise mode of 100/60 ° C for the developed soybean-spinach composition is safe for biologically active substances and it is justified by experimental temperature curves. Numerical modeling of heat and mass transfer during convective drying of crushed beets and crushed soybeans using the known model by A.V. Lykov satisfactorily describes the process and can be used to model the convection drying of colloidal capillary-porous materials.


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