scholarly journals Correlation Between Blood Lead Level (BLL) And Osteoporosis in Postmenopausal Women In Surabaya Indonesia

2017 ◽  
Author(s):  
Anita Dewi Moelyaningrum

This paper has been published in proceeding of The 1st International Symposium of Public Health "Emerging and Re-emerging Diseases. Nopember 30, 2016. pages 190-197. S3 Ilmu Kesehatan , Fakultas Kesehatan Masyarakat, Universitas Airlangga. Cetakan Pertama- Oktober 2017. Lead (Pb) compounds indicate that some toxic effects influence our health such of osteoporosis. This research was to identify the source of lead contamination and to analyze the association between blood lead level (BLL), the symptom of osteoporosis and occurence of osteoporosis among post menopause women. A cross- sectional study was conducted in Surabaya City Indonesia. The sample size was 60 persons, randomly selected from post menopause women age 50-65 years. The observed variables were lead blood level, assessed using atomic absorption spectrophotometry (AAS) and bone mineral density of spine and hip, assessed using Dual X-Ray Examination Absorbtiometry (DXA). The mean value of blood lead level was 11.135 μ/dL. Multiple regression showed that, there was significant correlation between the history of work and Blood lead level (p=0.037). There are significant association between fracture (p=0.027), bone fragility (p=0.008), spinal pain (p=0.016) with osteoporosis. Age (p=0.002), blood lead levell (p=0,055), calcium consumption (p=0.022) and exercise regularly (p=0.08) were together significant correlation with the occurence of osteoporosis. These variables increase the risk of osteoporosis, simultaneously. It implies that to prevent osteoporosis, the possible source of lead contamination should be avoided, meanwhile post menopause women shall improve calcium intake and doing exercise regularly.

2017 ◽  
Vol 15 (2) ◽  
pp. 35
Author(s):  
M ROMLI

Title : Association between Blood Lead Level and Learning Achievement on the Students at Grinting 01 Elementary School, Bulakamba District, Brebes RegencyBackground: Plumbum (Pb) is a highly poisonous heavy metal, especially for the children. Pb enters the human body through the respiratory and gastrointestinal tract, and also skin. The aim of this study was to determine the correlation between blood lead level and the learning achievement on the students in Grinting 01 Elementary School, Bulakamba District, Brebes Regency. Methods: This study was an observational research using cross sectional design.  The subjects were 51 students. The data were collected using interview and observational field. The exposure of blood lead level was measured by detecting Pb content in blood according to the result of laboratory test by ASS method (Atomic absorbance spectrometer), and the learning achievement was measured using MST (Middle Semester Test) score of the students. Univariate analysis and bivariate analysis (Chi-Square) were used to analyze the data. Results: The result of bivariate test indicated that there was no correlation between blood lead level and learning achievement with p >0.05. For in the ehole samples, the blood lead level were more than Normal standard of CDC (≥5 µg/dL) with the highest Pb in blood is 48.39 µg/dL and the lowest is 11.06 µg/dL. Conclusion: In conclusion, Pb concentration - in blood on the children does not influence the learning achievement directly.  


2018 ◽  
Vol 68 ◽  
pp. 03012
Author(s):  
Indah Lestari ◽  
Tri Edhi Budhi Soesilo ◽  
Haruki Agustina

Lead is one of the ten main chemicals that was found naturally in the earth's crust and has toxic effects to human health. Direct contamination due to the re-suspension of dust containing lead from soil can be inhaled by certain environmental conditions, for example in dry season and enter human body directly. The aim of this study was analyzing the effect of lead contamination toward human health in Pasarean Village.The research was conducted in Pesarean Village, Tegal District where metal smelting and used lead acid battery smelting had been done in more than 10 years ago and left the waste aside as an open dumping waste. The method that was used in this study were qualitative method using questionnaire and reviewing secondary data which was supported with literature reviews. The result showed that almost 80% of people has acute and chronic symptoms of lead poisoning and it showed that lead contained in blood was high or exceeding the blood lead level standard in human.


2006 ◽  
Vol 44 (2) ◽  
pp. 318-327 ◽  
Author(s):  
Kyeong-Ran KIM ◽  
Sang-Won LEE ◽  
Nam-Won PAIK

PLoS ONE ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. e0197856 ◽  
Author(s):  
Mohammad Jyoti Raihan ◽  
Emily Briskin ◽  
Mustafa Mahfuz ◽  
M. Munirul Islam ◽  
Dinesh Mondal ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Jintana Sirivarasai ◽  
Sukhumpun Kaojarern ◽  
Suwannee Chanprasertyothin ◽  
Pachara Panpunuan ◽  
Krittaya Petchpoung ◽  
...  

Lead has been linked to the development of hypertension via oxidative stress. Catalase plays an important role in the disposal of hydrogen peroxide in erythrocyte and its activity was determined by CAT gene. The aims of this study were to investigate (1) the association between blood levels of antioxidant markers such as catalase, superoxide dismutase, glutathione, glutathione peroxidase, oxidative stress-marker (malondialdehyde), and blood lead level and (2) the influence of genetic polymorphism of CAT gene (rs769217) on change in blood pressure in general population of EGAT study project. This is a cross-sectional study of 332 normotensive, 432 prehypertensive, and 222 hypertensive male subjects. Hypertensive subjects had significantly higher blood lead level (5.28 μg/dL) compared to normotensive (4.41 μg/dL) and prehypertensive (4.55 μg/dL) subjects (P<0.05). These significant findings are also found in MDA levels. Moreover, individuals with TT genotype in hypertensive group had significantly higher blood lead and MDA levels (6.06 μg/dL and 9.67 μmol/L) than those with CC genotype (5.32 μg/dL and 8.31 μmol/L,P<0.05). Our findings suggested that decreased blood catalase activity in this polymorphism together with low level lead exposure induced lipid peroxidation may be responsible for hypertension.


2018 ◽  
Vol 9 (1) ◽  
pp. 66
Author(s):  
Hendra Eka

Lead (Pb) is a metal that used as a color pigment in paint material. Lead has an acute effect on blood pressure and caused hypertension in chronic poisoning because it accumulated in blood. The objective of this research was to identify the correlation between aerial lead level and blood lead level with hypertension of workers in car painting workshop Surabaya. This research was an observational with cross-sectional study and to know the correlation analyzed by using phi correlation. Sample of this research were 16 respondents taken from population compatible from defi ned criteria. Blood lead level and blood pressure examined by the health workers then analyzed in the laboratory and using questionnaires to determine the characteristic of respondents. The results of this research is 83.33% respondents were exposed have blood lead concentration exceeds the limit that is > 10 μg/dL and 66.67% respondents were exposed have hypertension. Blood lead concentration have a strong correlation with hypertension (r = 0.618). The workers need to do a routine blood lead concentration check up once every 6 months and use personal protective equipment at work, consume foods and beverages that contain high calcium often nevertheless decrease smoking habit to inhibit absorption of lead in blood.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Shailja Sharma ◽  
Prasenjit Mitra ◽  
Pankaj Bhardwaj ◽  
Praveen Sharma

Abstract Objectives Lead exposure in children contributes to 600,000 new cases of intellectual disabilities every year with maximum occurrence in developing countries. Currently limited information is available on the blood lead level (BLL) in children of India. The aim was to estimate BLL in the school going children of local population of Jodhpur. Methods Four hundred twenty-six primary school children of government and private schools participated in this cross sectional study. Information regarding possible lead exposure was collected. BLL was estimated on Lead Care II analyser (Magellan Diagnostics, USA). Results The mean and median BLL were 4.25 ± 1.75 μg/dL (<3.3–22.6 μg/dL) and 3.5 μg/dL (Inter Quartile Range 0.9). BLL was higher in children of illiterate mothers, those residing near traffic dense areas, urban region and studying in government schools of urban region. Conclusions BLL in children residing in Jodhpur is much higher in comparison to western counterparts. Screening and awareness programs regarding potential sources of lead exposure can help in improving BLL.


2018 ◽  
Vol 10 (1) ◽  
pp. 92
Author(s):  
Nur Lathifah Syakbanah

Lead (Pb) is one of harmful pollutants for human health and environment. Therefore, the aim of study was to describe of air lead level and respondent characteristics toward blood lead level among pedicab drivers in Sukomulyo Street and Dr. Wahidin Sudirohusodo Street, Gresik Regency. It was an observational-analytical study using cross sectional design. Dependent variables was blood lead level, independent variables were air lead level, respondent characteristics include age, work period, smoking habit and number of cigarettes. Subjects were using snowball sampling 9 pedicab drivers on Sukomulyo Street and Dr. Wahidin Sudirohusodo Street. Data collection was using questionnaire, air lead level and blood lead level laboratory results. Data analysis was using descriptive. Result shows that air lead level were 1.69 × 10-4 and 1.60 × 10-4 mg/m3. Mean ± standard deviation among pedicab drivers in Sukomulyo Street and Dr. Wahidin Sudirohusodo Street for blood lead level (6.14 ± 0.51 μg/dl; 5.92 ± 0.18 μg/dl), age (59.20 ± 16.25 years; 44.75 ± 19.28 years), work period (24.00 ± 25.68 years; 4.00 ± 2.58 years), smoking habit (75.00%; 80.00%), number of cigarettes (> 10 cigarettes per day). It is concluded that air lead level and blood lead level fulfill limit value. It is suggested to choose rest area around roadside plants which is absorbing lead and consume calcium milk, routinely.


2014 ◽  
Vol 54 (3) ◽  
pp. 127
Author(s):  
Lilian Gunawan ◽  
Nurhayati Masloman

Background Lead poisoning is a source of health problems inhumans. A chronic complication oflead poisoning in children ispermanent intellectual impairment.Objective To assess for a correlation of blood lead levels andintelligence quotient (IQ) in children.Methods A cross-sectional study was performed in children aged6 to 8 years in th e Talawaan (a rural area) and Wenang (an urbanarea) Distticts, North Sulawesi, from April to July 2012. Blood leadlevels were measured using the graphite furnace atomic absorptionspectrometry technique; and intelligence was meas ured with theWechsler Intelligence Scale for Children-Indonesian version.Results There were 50 subjects from the Talawaan District and 54subjects from the Wenang Disttict in this study. The mean bloodlead level in the Talawaan District subjects was significantly higherthan that of the Wenang Disttict subjects [25.8 (SD 16.98) μgidLvs 11.4 (SD 13.81) μgidL, respectively; (P<0.001)]. There was aweak negative correlation between blood lead level and IQ in theTalawaan Disttict children (P= 0.038; r= -0.3). As such, there wasa 0.05 IQ point decrement associated with each increase of 1 μ gidLin blood lead level in Talawaan District children. However, therewas no correlation between blood lead level and IQ in the WenangDisttict children (P=0.42; r =0.03).Conclusion There is a weak negative correlation between bloodlead level and IQ in children living in a rural area, howevei; thiscorrelation is not found in children living in an urban area.


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