scholarly journals Prevalence of sleep – wake cycle disturbance among cancer patients of Bhaktapur cancer hospital, Nepal

2017 ◽  
Vol 6 (2) ◽  
pp. 6-13
Author(s):  
P Marita ◽  
R Acharya Pandey
Keyword(s):  
Cancer Patients ◽  
Sleep Disturbances ◽  
Demographic Data ◽  
Severity Index ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Cancer Hospital ◽  
Chi Square Test ◽  
Clinically Significant

 Cancer patients are at great risk for developing insomnia and disorders of the sleep-wake cycle. Insomnia is the most common sleep disturbance in this population and is most often secondary to physical and/or psychological factors related to cancer and/or cancer treatment. It is estimated that nearly 45% of cancer patients experience sleep disturbances; this is nearly three times the estimate of its occurrence in the general population. The purpose of the study is to determine the prevalence of sleep-wake cycle disturbance in patient receiving chemotherapy. A descriptive cross-sectional study was carried out in 2013. A total of 205 respondents, visiting Bhaktapur Cancer Hospital and who met criteria were purposively sampled and interviewed face to face. Insomnia Severity Index Scale was used to grade insomnia. Descriptive statistics such as frequency and percentage was used to describe demographic data. Chi-square test was done to find out the association between prevalence of sleep-wake cycle disturbance and selected variables. Among the total respondents (205), 70.7% had sleep-wake cycle disturbances. Majority (71.21%) of respondents had some form of clinically significant insomnia. The ages of the respondents ranged from 20 to 81 years with the mean age of 56.25 (SD ± 13.87). More than half i.e. 69.3% of the respondents were female. Patients being treated with Methotrexate were found to be more associated with the development of sleep-wake cycle disturbance. The significant association was found on drinking tea/coffee with the prevalence sleep-wake cycle disturbance. Sleep disorders are a common and often chronic problem for patients with cancer. Recently, such symptoms have attracted little attention. This might be the reasons for increased prevalence of sleep-wake cycle disturbance. It is recommended to take early and adequate intervention for the reduction of increased prevalence rate of sleep-wake cycle disturbance. 

scholarly journals Drug interactions between antineoplastic and antidepressant agents: analysis of patients seen at an oncology clinic at a general hospital

2015 ◽  
Vol 37 (2) ◽  
pp. 87-93
Author(s):  
Camila de Araújo Reinert ◽  
Marcelo Rodrigues Ribas ◽  
Paulo Roberto Zimmermann
Keyword(s):  
Depressive Symptoms ◽  
Drug Interactions ◽  
Cancer Patients ◽  
Antineoplastic Agents ◽  
Cross Sectional Study ◽  
Oncology Patients ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Simultaneous Use

Objectives: To determine the prevalence of depressive symptoms among oncology patients and identify simultaneous use of antineoplastic and antidepressant agents.Methods: This was a cross-sectional study that interviewed 56 oncology patients using two data collection instruments: a questionnaire covering clinical and sociodemographic data and the Beck Depression Inventory-II (BDI-II), for assessment of depressive symptoms. For data analysis, descriptive statistics were used to determine the prevalence of depressive symptoms and the chi-square test was used to evaluate associations between sociodemographic and clinical variables and depressive symptoms.Results: A 26.7% (15 patients) prevalence of depression was detected. Just eight of these 15 patients (53.3%) were receiving treatment for depression. In the sample as a whole, 13 of the patients interviewed (23.2%) were taking antidepressants and 11 of these 13 patients (19.6%) were taking antidepressive and antineoplastic agents simultaneously. A total of five (8.9% of the sample) contraindicated drug interactions were detected.Conclusions:Depressive symptoms are more prevalent among cancer patients than in the general population, but they are generally under-diagnosed and under-treated. Simultaneous use of antidepressant and antineoplastic agents is common and so, in order to reduce the number of harmful adverse effects, possible drug interactions must be identified before antidepressants are prescribed to cancer patients.

scholarly journals Nationality as a risk factor of tuberculosis resistance in two co-related countries

2018 ◽  
Vol 18 (1) ◽  
pp. 36-41
Author(s):  
Ali Afaghi Gharamaleki ◽  
Seyyedreza Moaddab ◽  
Mojtaba Darbouy ◽  
Khalil Ansarin ◽  
Shahram Hanifian
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Demographic Data ◽  
Medical Science ◽  
Drug Susceptibility ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Lowenstein Jensen

Background: Republic of Azerbaijan and Iran are two neighboring countries with high amount of travelling between them, different rates of TB and its resistance. These relationships could complicate the controlling of tuberculosis programs. Objective: The study was conducted to determine the prevalence of tuberculosis (TB) resistance and its risk factors in the two geographically co-related regions. Method: A total of 119Mycobacterium tuberculosis isolates from the patients of the target regions (Azerbaijan Rep. and Tabriz, Iran) were examined at the Central Tuberculosis Laboratory in Tabriz, Iran. The cultures and drug susceptibility tests was performed on Lowenstein-Jensen. All the isolates were categorized by MIRU-VNTR molecular method into clustered and un-clustered groups. The clustering as well as demographic data were analyzed to determine the risk factors contributing to TB resistance. The categorical data about the TB resistance were compared using a chi square test. Results: 27.8 percent of isolates were resistant at least to one of the 1st line of anti-tuberculosis drugs. The prevalence of any drug resistance and MDR were 64.6 and 17.9 percent respectively for Azari isolates, where the rate of resistance to rifampin and isoniazid was higher than streptomycin and ethambutol. The corresponding figures for the isolates from Tabriz were 16.9 and 3.3 percent respectively. Conclusions: The results of this comparative and cross-sectional study showed statistically significant differences in TB resistance between the isolates from the patients of Azerbaijan Rep. and Iran. According to the results, the rate of resistance to RMP, INH, and MDR was higher in Azerbaijan; consequently, nationality could be regarded as a risk factor of MDR, resistance to RMP and INH but not to SM and ETB. Other studied parameters did not contribute to TB resistance. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.36-41

scholarly journals Complementary and Integrative Medicines Used by Cancer Patients to Cope With Chemotherapy-Related Taste Alterations

2022 ◽  
Vol 32 (1) ◽  
pp. 69-77
Author(s):  
Tugbamenekli Tugbamenekli ◽  
◽  
Yasemin Yildirim ◽  
Keyword(s):  
Cancer Patients ◽  
Multivariate Logistic Regression Analysis ◽  
Primary Source ◽  
Cross Sectional Study ◽  
Study Data ◽  
Chi Square ◽  
Cross Sectional ◽  
Complementary And Integrative Medicine ◽  
Chi Square Test ◽  
The Mean

Introduction: Cancer is a global health problem. Taste change is one of the most common symptoms in cancer patients undergoing chemotherapy. Cancer patients often use Complementary and Integrative Medicine (CIM) to manage chemotherapy complications. Objective: This study aimed to evaluate CIM used by cancer patients to cope with chemotherapy-related taste alterations. Materials and Methods: This cross-sectional study was carried out on 318 cancer patients receiving chemotherapy in an oncology hospital in Malatya City, Turkey. The samples were recruited by convenience sampling method. The study data were collected with a data form developed by the research team. Written permissions were obtained from all participants and the Ethics Committee. Frequencies, mean scores, and standard deviation were used to present descriptive findings. The independent t-test, Chi-square test, and multivariate logistic regression analysis were used to analyze the obtained data. Results: The Mean±SD age of the patients was 65.18±8.36 years, and the mean duration of their diseases was 35.34±16.27 months. About 54.1% of the patients were female, and 42.8% had some information about CIM. Their primary source of information was other patients (49.6%), and 34.9% used CIM to cope with chemotherapy-related taste alterations. The most common method used was phytotherapy (50.5%), and the most commonly used herb was miracle fruit (21.4%). It was also determined that the frequency of CIM use was affected by age, illness duration, gender, living in a city, family history of cancer, having breast cancer, having information on CIM, having metastasis, and lacking complications (R2= 0.426, P=0.025). Conclusion: Cancer patients frequently use CIM to cope with chemotherapy-related taste alterations, and phytotherapy was the most commonly-used CIM.

scholarly journals Investigation of Depression in Cancer Patient’s Caregivers in Combined Military Hospital, Rawalpindi

2021 ◽  
Vol 10 (3) ◽  
pp. 154-159
Author(s):  
Hafiz Muhammad Awais Ghaffar ◽  
Mahwish Ujala ◽  
Muhammad Sohaib Nadeem ◽  
Humaira Mahmood ◽  
Syed Aftab Rahim ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Employment Status ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
Chi Square ◽  
Cross Sectional ◽  
Demographic Questionnaire ◽  
High Prevalence ◽  
Prevalence Of Depression ◽  
Chi Square Test

Background: Cancer is the second leading cause of death, responsible for 1 in 6 deaths globally and Caregivers play a major role in cancer patients' care and rehabilitation. They may face several psychological issues like depression along with physical and emotional disadvantages, and significant financial consequences. The objective of this study is to find out the associations of Depression with demographic variables among family caregivers of cancer patients in combined Military Hospital, Rawalpindi. Methods: This was a cross-sectional study conducted in the OPD and IPD of the Oncology department of CMH, Rawalpindi between February and July 2020. The 384 adult cancer patient’s caregivers visiting oncology department were assessed to find out level of depression after getting informed consent. Data was collected by Demographic questionnaire and Beck Depression Inventory (BDI) tool. Chi-square test and Likelihood ratio chi-square test used to find association. Results: Out of all 384 caregivers 181 (47.1 %) were males and 203 (52.9 %) were females. 267 (69.5 %) were diagnosed as non-depressive while 117 (30.5 %) were diagnosed as Depressive. A considerable association has been found between Depression and Age of caregivers (p= 0.006), Gender of caregivers (p <0.05), employment status of caregivers (0.02) and relationship to a cancer patient (p = 0.003). Conclusion: A high prevalence of depression is found in cancer patient’s caregivers and Depression is significantly associated with Age of caregivers, Gender of caregivers, employment status of caregivers, and the relationship to cancer patients.

scholarly journals Correlation between levels of LGR-5 (leucine rich repeat containing protein coupled receptor 5) with clinical aspects and colorectal carcinoma stage

2021 ◽  
Vol 5 (3) ◽  
pp. 331-343
Author(s):  
Mendila P Arungpadang ◽  
Ronald E Lusikooy ◽  
Firdaus Kasim ◽  
Mappincara Mappincara ◽  
Warsinggih Warsinggih
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Carcinoma ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Clinical Aspects ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Evaluation Stage ◽  
Contradiction Analysis

This study analyzes the colorectal cancer refers to gradually growing cancer that begins as tumor or tissue development in the internal layer of the rectum or stomach. CRC is resistant to chemotherapy and radiation and can cause collapse. This study is an analytical observational study using a cross-sectional study design with an evaluation stage of increasing LGR-5 levels on clinical aspects and stages of Colorectal Carcinoma patients in Makassar. Data collection was primary, where the data taken was demographic data and related to clinical aspects of the patient, namely, age, gender, cancer location, and cancer stage, lymph node participation, histopathological type when the patient came to treatment with diagnosis of colorectal cancer. The non-sanskari analysis was carried out on variables from the results of the study using contradiction analysis to determine the relationship between the increased level of LGR-5 and the stage of carcinogen ma patients based on AJCC. The analysis was carried out with the chi-square test. The value of significance is obtained when p <0.05.

scholarly journals Molar Incisor Hypomineralization, prevalence, pattern and distribution in Sudanese children

2020 ◽  
Author(s):  
Hanna Elhassan Abdalla ◽  
Amal Hussein Abuaffan ◽  
Arthur Musakulu Kemoli
Keyword(s):  
Demographic Data ◽  
Rank Correlation ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Related Factors ◽  
Cross Sectional ◽  
Tooth Structure ◽  
Molar Incisor Hypomineralization ◽  
Significant Difference ◽  
Chi Square Test

Abstract Background: Molar incisor hypomineralization (MIH) has serious impact on oral health-related quality of life for a child, due to its effects on tooth structure, aesthetics and behavior of the child. The current study was designed to determine the prevalence, pattern and distribution of MIH in school children in Sudan.Methods: This was a descriptive cross-sectional study involving 568 children, aged 8-11 years from schools in Khartoum State. Following collecting their socio-demographic data, the children were examined for hypomineralization on the 12 MIH indexed teeth, and assessed on the MIH pattern and distribution. The data collected were analyzed to obtain descriptive statistics, and the results related to the socio-demographic and other dental-related factors of the children using chi-square test and Spearman Rank Correlation, with the significant level set at P<0.05.Results: The prevalence of MIH in the study population was 20.1%. The majority of cases had both permanent first molars (PFMs) and permanent incisors affected (12.5%). However, in 7.6% of the cases, only molars were affected. Even though more maxillary teeth were affected when compared to the mandibular teeth, there is no statistical significant difference between the occurrence of hypomineralization on mandibular and maxillary molars (P=0.22). Maxillary incisors were significantly more affected by MIH when related to the mandibular ones (P=0.00). Demarcated opacities were the commonest pattern of MIH defects (69.9%) in the experimental group.Conclusion: The prevalence of MIH in Sudanese children was 20.1%. In both dental arches, the permanent molars and incisors were frequently affected, with the demarcated opacity type of MIH being the most common form of defect. Further studies are recommended to better understand the possible etiologies of MIH in Sudanese children.

scholarly journals Molar Incisor Hypomineralization, prevalence, pattern and distribution in Sudanese children

2021 ◽  
Author(s):  
Hanna Elhassan Abdalla ◽  
Amal Hussein Abuaffan ◽  
Arthur Musakulu Kemoli
Keyword(s):  
Demographic Data ◽  
Rank Correlation ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Related Factors ◽  
Cross Sectional ◽  
Tooth Structure ◽  
Molar Incisor Hypomineralization ◽  
Significant Difference ◽  
Chi Square Test

Abstract Background: Molar incisor hypomineralization (MIH) has serious impact on oral health-related quality of life for a child, due to its effects on tooth structure, aesthetics and behavior of the child. The current study was designed to determine the prevalence, pattern and distribution of MIH in school children in Sudan.Methods: This was a descriptive cross-sectional study involving 568 children, aged 8-11 years from schools in Khartoum State. Following the collection of their socio-demographic data, the children were examined for hypomineralization on the 12 MIH-index teeth, the pattern and distribution of the MIH. The data collected was analyzed to obtain descriptive statistics. The results related to the socio-demography and other dental-related factors were tested using chi-square test and Spearman Rank Correlation, with the significant level set at P<0.05.Results: The prevalence of MIH in the study population was 20.1%. The majority of the participants had both permanent first molars (PFMs) and permanent incisors affected (12.5%). However, in 7.6% of the cases only molars were affected. Even though more maxillary teeth were affected when compared to the mandibular teeth, there was no statistical significant difference between the occurrence of hypomineralization on mandibular and maxillary molars (P=0.22). Maxillary incisors were significantly more affected by MIH when related to the mandibular ones (P=0.00). Demarcated opacities were the commonest pattern of MIH defects (69.9%) in the experimental group.Conclusion: The prevalence of MIH in Sudanese children was 20.1%. In both dental arches, the permanent molars and incisors were frequently affected, with the demarcated opacity type of MIH being the most common form of defect.

scholarly journals Molar incisor hypomineralization, prevalence, pattern and distribution in Sudanese children

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hanna E. Abdalla ◽  
Amal H. Abuaffan ◽  
Arthur Musakulu Kemoli
Keyword(s):  
Demographic Data ◽  
Rank Correlation ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Related Factors ◽  
Cross Sectional ◽  
Tooth Structure ◽  
Molar Incisor Hypomineralization ◽  
Significant Difference ◽  
Chi Square Test

Abstract Background Molar incisor hypomineralization (MIH) has serious impact on oral health-related quality of life for a child, due to its effects on tooth structure, aesthetics and behavior of the child. The current study was designed to determine the prevalence, pattern and distribution of MIH in school children in Sudan. Methods This was a descriptive cross-sectional study involving 568 children, aged 8–11 years from schools in Khartoum State. Following the collection of their socio-demographic data, the children were examined for hypomineralization on the 12 MIH-index teeth, the pattern and distribution of the MIH. The data collected was analyzed to obtain descriptive statistics. The results related to the socio-demography and other dental-related factors were tested using chi-square test and Spearman Rank Correlation, with the significant level set at p < 0.05. Results The prevalence of MIH in the study population was 20.1%. The majority of the participants had both permanent first molars (PFMs) and permanent incisors affected (12.5%). However, in 7.6% of the cases only molars were affected. Even though more maxillary teeth were affected when compared to the mandibular teeth, there was no statistical significant difference between the occurrence of hypomineralization on mandibular and maxillary molars (p = 0.22). Maxillary incisors were significantly more affected by MIH when related to the mandibular ones (p = 0.00). Demarcated opacities were the commonest pattern of MIH defects (69.9%) in the experimental group. Conclusion The prevalence of MIH in Sudanese children was 20.1%. In both dental arches, the permanent molars and incisors were frequently affected, with the demarcated opacity type of MIH being the most common form of defect.

IDENTIFIKASI SERTA HUBUNGAN KONSTRUKSI SUMUR GALI TERHADAP KANDUNGAN COLIFORM PADA AIR SUMUR GALI DI DUSUN JIKEN KABUPATEN LOMBOK TIMUR

2019 ◽  
Vol 7 (2) ◽  
pp. 115
Author(s):  
Dini Yuliansari
Keyword(s):  
Cross Sectional Study ◽  
Coliform Bacteria ◽  
Well Water ◽  
Chi Square ◽  
Cross Sectional ◽  
Content Variable ◽  
Chi Square Test ◽  
Dug Wells ◽  
Dug Well ◽  
The Relationship

The well is one of the source water used for bathing, washing, and drinking by the citizens in Jiken Hamlet, Rarang Village, Terara Sub-District. Poor dug well construction conditions can affect the amount of coliform bacteria contained in the dug well water. The purpose of this study is to identify the construction of dug wells and the content of coliform bacteria in dug well water and determine the relationship between dug well construction and the content of coliform bacteria. This research is analytic with a cross sectional study design. The results were obtained from 11 samples of dug wells which were observed in construction and the coliform content was known that all samples did not requirements as good dug well construction. Coliform content test results showed that as many as 5 dug well water samples did not pass the clean water quality standards. The results of data analysis with the chi-square test variable construction of dug wells with coliform content variable  showed 0,172 > 0,05, then the concluded is the dug well not suitable to use by people in that area as a source of water for daily needs.

Socio-Demographic Factors and Health-Related Behaviors Associated with Gerontology

GIS Business ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. 359-370
Author(s):  
Dr. Ravi S. Dalawai
Keyword(s):  
Cross Sectional Study ◽  
Work Culture ◽  
Chi Square ◽  
Cross Sectional ◽  
The Social ◽  
Health Related ◽  
Chi Square Test ◽  
Current Scenario ◽  
Socio Demographic Factors ◽  
Insight Into

Indian population is in growing trend from 942.2 million in 1994 to 1.36 billion in 2019.Among this six per cent of India's population was of the age 65 and above (UNFPA, 2019). Today the work culture is totally changed. Both husband and wife are forced to work in the current scenario and unable to take care of their parents. The changing structure created increased problems for old age people leads to loneliness, psychological, physical health and financial insecurity. The study paper provides insight into the social and demographic factor and health related sickness of the oldest people. This research explained the cross-sectional study included a representative sample (n=116) of adults aged ≥60 years. The sample was chosen using a four-stage stratified random-cluster survey sampling method .The Chi Square test and ANOVA test was analyzed using SPSS20.

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