scholarly journals Mirror of surgeries of gall stones diseases in Lumbini Zonal Hospital

2018 ◽  
Vol 8 (2) ◽  
pp. 23-26
Author(s):  
Narad Prasad Thapaliya ◽  
Krishna Prasad Khanal ◽  
Bhuwan Poudel ◽  
Sharad Pokharel ◽  
Ruckmeni Sharma
Keyword(s):  
Bile Duct ◽  
Hospital Stay ◽  
Surgical Procedure ◽  
Age Distribution ◽  
Common Cause ◽  
Demographic Profiles ◽  
Outpatient Consultation ◽  
Gall Stones ◽  
The World ◽  
Record Section

Introduction: Cholelithiasis is common cause for surgical outpatient consultation. Cholecystectomy is most common surgical procedure performed as elective basis in Lumbini Zonal Hospital, Butwal. The aim of this study is to show the mirror of surgeries of gall stones diseases in Lumbini Zonal Hospital, Butwal. Methods: A retrospective analysis of cholecystectomy performed in Lumbini Zonal Hospital over a period of 5 years (Biasakh 2069BS- Chaitra 2073BS) was done after the approval from ethical committee. Demographic profiles, complications and other required information were retrieved from the documents available in medical record section. Results: Total of 372 cholecystectomies were done for different spectrum of gallstones diseases during the study period. Most of the patients were female (341, 92%). The age distribution of the operated patients was 17 years to 75 years. Most of the operated patients (190, 51.07%) were in their productive age (17- 40 years). Most common complications found post operatively were chest infection, SSI. Mid hospital stay was 3.16 days (1-6 days). Total bile duct injury was 1 (0.26%) comparable to other studies. Conclusion: Cholecystectomy is one of the most common operative procedures performed in our hospital with postoperative outcomes comparable to reported outcomes of other institutions of the world.

scholarly journals Precancerous Lesions in Colorectal Cancer

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Fayez Sandouk ◽  
Feras Al Jerf ◽  
M. H. D. Bassel Al-Halabi
Keyword(s):  
Colorectal Cancer ◽  
Precancerous Lesions ◽  
Middle Eastern ◽  
Age Distribution ◽  
The West ◽  
Genetic Studies ◽  
Common Cause ◽  
The Third ◽  
The World ◽  
Surveillance Programs

Colorectal cancer (CRC) is the third most common cause of cancer death in the world. The incidence rate (ASR) and age distribution of this disease differ between most of African-Middle-Eastern (AMAGE) and North America and Europe for many reasons. However, in all areas, “CRC” is considered as one of the most preventable cancers, because it might develop from variant processes like polyps and IBD in addition to the genetic pathogenesis which became very well known in this disease. We tried in this paper to review all the possible reasons of the differences in incidence and age between the west and AMAGE. Also we reviewed all the mutations that lead to the hereditary and familiar clustering of this disease with the correlations with the surrounding food and environment of different areas. Then, we focused on the precancerous pathology of this disease with special focusing on early detection depending on new endoscopy technology and most important genetic studies. We lastly reviewed the evidence of some of the surveillance and put suggestions about future surveillance programs and how important those programs are on the psychological aspect of the patients and their families.

Thrombolytic Treatment of Acute Cerebral Infarction

CNS Spectrums ◽  
2005 ◽  
Vol 10 (7) ◽  
pp. 539-549 ◽  
Author(s):  
Kathleen M. Burger ◽  
Deborah R. Horowitz
Keyword(s):  
Case Reports ◽  
Optimal Management ◽  
Thrombolytic Treatment ◽  
Acute Stroke Patient ◽  
Acute Therapy ◽  
Common Cause ◽  
Intravenous Tissue Plasminogen Activator ◽  
The World ◽  
Tissue Plasminogen ◽  
Improved Outcome

AbstractStroke is a common cause of death and disability throughout the world. Acute neurologic deficits due to ischemic injury deserve rapid recognition and diagnosis in order to provide effective therapy. Intravenous tissue plasminogen activator (t-PA) provided to carefully selected patients that can be treated within 3 hours of stroke onset results in improved outcome in these patients. Intra-arterial administration of t-PA within a 6-hour window is performed at several academic centers in patients with middle cerebral and other intracranial artery occlusions based on results of one randomized clinical trial and numerous case reports. Although acute therapy of ischemic stroke has received much attention since the approval of intravenous t-PA, only a small percentage of individuals suffering a stroke actually receive t-PA. This article will review the optimal management of the acute stroke patient and discuss thrombolytic clinical trials that have been completed as well as those that are in progress.

scholarly journals Pathophysiology of Depression and Novel Sources of Phytochemicals for its Treatment – A Systematic Review

2020 ◽  
Vol 47 (4) ◽  
pp. 69-74
Author(s):  
D. Bakalov ◽  
R. Hadjiolova ◽  
D. Pechlivanova
Keyword(s):  
Conventional Treatment ◽  
Literature Search ◽  
Drug Reactions ◽  
Major Depressive ◽  
Common Cause ◽  
Literature Research ◽  
Morphological Alterations ◽  
The World ◽  
Biochemical Genetic ◽  
Standard Set

AbstractThe rising burden of depression, which will soon be the second most common cause of disability in the world, is requesting new ways to treat and prevent it. Due to high number of significant adverse drug reactions of the conventional treatment, the modern pharmaceutical industry is more often turning their focus to novel plant-based solutions. We performed literature research based on standard literature search engines – PubMed, Google Scholar, Science Direct. A standard set of keywords related to our topic e.g. “Depression”, “Mesembrine type alkaloids”, “Narcissus” was used. The review describes the classical monoamine theory of depression and connects it with the newly found biochemical, genetic and morphological alterations associated with the major depressive disorder. The purpose of this review is to highlight the most important aspects of the pathophysiology of depression and to explore the possibilities to use mesembrine-like alkaloids isolated from Narcissus cv. Hawera in its treatment. We describe their effect on brain biochemistry and possible future investigations.

scholarly journals Bile acid diarrhoea: from diagnosis to treatment

2020 ◽  
Vol 18 (5) ◽  
pp. 36-41
Author(s):  
V.P. Novikova ◽  
◽  
L.N. Belousova ◽  
Keyword(s):  
Bile Acid ◽  
Bile Duct ◽  
Bile Acids ◽  
Enterohepatic Circulation ◽  
Diet Therapy ◽  
Diagnostic Methods ◽  
Chronic Diarrhoea ◽  
Common Cause ◽  
Diagnosis And Management

Bile acid diarrhoea is a common cause of chronic diarrhoea associated with disturbance of the enterohepatic circulation: either excessive biosynthesis/secretion of bile acids or disordered absorption of bile acids in the ileum. At the same time bile acid diarrhoea is an insufficiently studied, frequently underestimated condition, and the questions remain concerning its diagnosis and management. The work discusses the main groups of causes of this pathology, modern diagnostic methods and the difficulties of a differential search. Also, the article offers information about the diet therapy of bile duct diarrhoea and the main groups of administered medications, in particular, modern enterosorbents.

scholarly journals Three Cases of Difficult Bile Duct Stone Removal by EUS-guided Choledochoduodenostomy

2020 ◽  
Vol 25 (2) ◽  
pp. 128-134
Author(s):  
Yeong Joo Jeong ◽  
Man Ki Choi ◽  
Seung Goun Hong
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Hospital Stay ◽  
Bile Duct Stone ◽  
Intrahepatic Bile Duct ◽  
Safe Procedure ◽  
Bile Duct Stones ◽  
Metal Stent ◽  
Endoscopic Retrograde ◽  
Duration Of Hospital Stay

After failed removal of common bile duct or intrahepatic bile duct (IHD) stones by endoscopic retrograde cholangiopancreatography (ERCP), percutaneous lithotripsy is well-known as an effective procedure. However, it is time-consuming because multiple sessions of transhepatic tract dilatation are required. Endoscopic ultrasound (EUS)-guided choledochoduodenostomy (CDS) has been recently used to approach IHD to remove difficult bile duct stones. We recently experienced EUS-guided CDS performed with metal stent. Common bile duct or IHD stones were removed by retrieval accessories after initial failed or inadequate ERCP in three patients. Serious complications including bleeding, infection, and perforation were not noted. The duration of hospital stay from EUS-guided procedure to discharge ranged from 10 to 14 days. Although this result is interim and ongoing, it suggests that EUS-guided CDS might be an effective and safe procedure after failed ERCP to remove difficult bile duct stones through the tract.

scholarly journals Role of Ayurved in the Management of Wound Dehiscence - A Case Report

2021 ◽  
Vol 12 (2) ◽  
pp. 395-397
Author(s):  
Kiran Pundlikrao Mendhekar ◽  
Sanjay Babar ◽  
Ashwin Shete
Keyword(s):  
Case Report ◽  
Hospital Stay ◽  
Surgical Procedure ◽  
Fluid Collection ◽  
Fatal Outcome ◽  
Wound Dehiscence ◽  
Wound Management ◽  
Invasive Technique ◽  
Team Approach ◽  
Obese People

Wound dehiscence is the common problem which is faced by most of the surgeons in case of obese people. As we know, in case of post-operative wound management, avascularity and excessive adipose tissue lysis can lead to fluid collection which leads to gapping of sutured wound. This may also cause Dushta vrana i.e. secondary infection to the wound. Wound dehiscence in surgical field leads to most fatal outcome which can lead to cause local as well as systemic sepsis in the patient. Present case report reveals a treatment modality which involves multidisciplinary team approach such as management of wound as well as obesity by using Ayurvedic perspective. Whereas modern technique of resuturing the gapped wound exposes patient to another surgical procedure which is expensive and increases the hospital stay. The local and oral drugs formulations were proven effective in reducing excessive wound discharge as well as they stimulate the wound healing mechanism when administered in both local and systemic ways. The cost and benefit ratio was found high as there is no re-exposure to the surgical procedure and patient will get benefitted with non-invasive technique along with minimal expenses and hospital stay.

Introduction

2020 ◽  
pp. 1-17
Author(s):  
Bradley C. Smith
Keyword(s):  
Religious Faith ◽  
Business Leaders ◽  
Corporate America ◽  
Common Cause ◽  
Religious Traditions ◽  
Faith At Work ◽  
Modern Capitalism ◽  
Religious Convictions ◽  
The World

While some are wary of trends that encourage the interpenetration of faith and business, others welcome such integration, seeing in Christianity and other religious traditions dispositions that could challenge unhealthy characteristics and consequences of modern capitalism. Some have in fact come to believe that religious faith represents a wellspring of resources and concern that might help reshape corporate America by re-humanizing business and fortifying its ethical moorings. Given the world-changing energy evangelicals possess, evangelical business leaders in particular are candidates to initiate such reform as they attempt to do business in ways that are compatible with their religious convictions. For better or worse, evangelical executives could also advance a religious agenda if they join together in common cause, as some have suggested characterizes the faith at work movement. While evangelical business leaders certainly state that their faith influences their work, the nature and effect of such influence is often unexpected.

scholarly journals Impact of nanosystems in Staphylococcus aureus biofilms treatment

2019 ◽  
Author(s):  
Rita M Pinto ◽  
Daniela Lopes-de-Campos ◽  
M Cristina L Martins ◽  
Patrick Van Dijck ◽  
Cláudia Nunes ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Therapy ◽  
Economic Burden ◽  
Surgical Procedure ◽  
Healthcare Systems ◽  
World Health ◽  
Small Particles ◽  
The World ◽  
New Strategy ◽  
Health Organization

ABSTRACT Staphylococcus aureus (S. aureus) is considered by the World Health Organization as a high priority pathogen for which new therapies are needed. This is particularly important for biofilm implant-associated infections once the only available treatment option implies a surgical procedure combined with antibiotic therapy. Consequently, these infections represent an economic burden for Healthcare Systems. A new strategy has emerged to tackle this problem: for small bugs, small particles. Here, we describe how nanotechnology-based systems have been studied to treat S. aureus biofilms. Their features, drawbacks and potentialities to impact the treatment of these infections are highlighted. Furthermore, we also outline biofilm models and assays required for preclinical validation of those nanosystems to smooth the process of clinical translation.

scholarly journals CANVAS: a late onset ataxia due to biallelic intronic AAGGG expansions

2020 ◽  
Author(s):  
Natalia Dominik ◽  
Valentina Galassi Deforie ◽  
Andrea Cortese ◽  
Henry Houlden
Keyword(s):  
Late Onset ◽  
Replication Factor C ◽  
Common Cause ◽  
Progressive Ataxia ◽  
The World ◽  
Recent Developments ◽  
C Subunit ◽  
Repeat Expansions ◽  
Visual Problems ◽  
Factor C

Abstract The ataxias are a group of disorders that manifest with balance, movement, speech and visual problems. They can arise due to dysfunction of the cerebellum, the vestibular system and/or the sensory neurons. Genetic defects are a common cause of chronic ataxia, particularly common are repeat expansions in this group of conditions. Co-occurrence of cerebellar ataxia with neuropathy and vestibular areflexia syndrome has been termed CANVAS. Although CANVAS is a rare syndrome, on discovery of biallelic expansions in the second intron of replication factor C subunit 1 (RFC1) gene, we and others have found the phenotype is broad and RFC1 expansions are a common cause of late-onset progressive ataxia. We aim to provide a review and update on recent developments in CANVAS and populations, where the disorder has been reported. We have also optimised a protocol for RFC1 expansion screening which is described herein and expanded phenotype after analysing late-onset ataxia patients from around the world.

Sign in / Sign up

Export Citation Format

Share Document