scholarly journals Clinical Spectrum- Cognition, Stages, Functionality among Elderly with Dementia: A Cross-Sectional Study

2020 ◽  
Vol 18 (1) ◽  
pp. 3-7
Author(s):  
Niju Niroula
Keyword(s):  
Mini Mental State Examination ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Dementia Patients ◽  
Severe Impairment ◽  
Diagnosis Of Dementia ◽  
Functional Autonomy ◽  
The Mean ◽  
Severity Of Dementia ◽  
State Examination

Introduction: Although cognitive and functional impairment are the hallmark features of Dementia but it is often undetected and neglected as a normal part of aging. So we conducted this study on clinical profile of dementia patients. Aims: The aim of this study is to evaluate the Patient’s cognitive impairment, functional capacities, and stages of severity of dementia. Methods: A descriptive cross sectional study was conducted among 50 patients aged 60 years and above, of both sexes with the diagnosis of Dementia, admitted in Medicine ward of Nepalgunj Medical College, Nepalgunj, Nepal. The screening of dementia was done using Mini-Mental State Examination tool and the diagnosis of Dementia was confirmed using the International Classification of Disease-10 Diagnostic Criteria for Research. Cognition, functionality and stages of severity of dementia were assessed using Hierarchic Dementia Scale, Functional Autonomy Measurement System, Functional Assessment Staging Test tools respectively. Results: Among a total of 50 dementia patients, the mean and standard deviation of age was 82.4±6.1 years, majority of cases 60 % were in the age group ≥85 years and most patients were female 56%. The mean Mini-Mental State Examination score was 9.6±3.0, and 50 % had severe impairment of cognition on Hierarchic Dementia Scale. Stage 7 dementia 32 % was most prevalent stage on Functional Assessment Staging and severe deterioration in the functional autonomy was seen in 54% dementia patients (score ≥41 on Functional Autonomy Measurement System). Conclusion: This study concludes that significant number of elderly patients attending tertiary care hospital suffers from dementia with severe impairment in cognition and functionality in various stages of dementia in the elderly patients.

scholarly journals Etiological Pattern of Dementia in Bangladesh

2016 ◽  
Vol 32 (2) ◽  
pp. 85-90
Author(s):  
MRK Khan ◽  
AN Rizvi ◽  
MA Habib ◽  
MK Hasan ◽  
A Mamun ◽  
...  
Keyword(s):  
Vascular Dementia ◽  
Neurodegenerative Disorder ◽  
Psychosocial Interventions ◽  
Cross Sectional Study ◽  
Chronic Subdural Haematoma ◽  
Cross Sectional ◽  
Dementia Patients ◽  
Dsm Iv ◽  
Medical University ◽  
State Examination

Background: Dementia is a chronic & progressive neurodegenerative disorder affecting usually older people of more than 65 years in which there are disturbances of multiple higher cortical functions including memory, thinking, orientation & others. Dementia patients are increasing in number as the population of older age group is increasing. All types of dementia are treatable, at least with psychosocial interventions. So, accurate diagnosis and evaluation of etiological pattern is essential. Methods: This cross sectional study was carried out in the Department of Neurology, Bangabandu Sheikh Mujib Medical University, Dhaka, Bangladesh from January 2012 to December 2012 on 88 patients with dementia diagnosed on the basis of mini mental state examination and DSM-IV criteria. Results: Vascular dementia was the underlying diagnosis in most of the cases (43.3 %) followed by Alzheimers Disease (20.2%) and Parkinson Disease (9%). Other causes were Mixed Dementia, Intracranial Space Occupying Lesion, Post Encephalitic, Hypoxic Encephalitic, Chronic Subdural Haematoma and Tubercular Meningitis. Conclusion: Vascular dementia is more than Alzheimer’s Dementia in Bangladesh. Multiple vascular risk factors contribute to this. Bangladesh Journal of Neuroscience 2016; Vol. 32 (2): 85-90

Apolipoprotein E, Cognitive Function, and Dementia in a General Population Aged 85 Years and Over

2000 ◽  
Vol 12 (3) ◽  
pp. 379-387 ◽  
Author(s):  
Kati Juva ◽  
Auli Verkkoniemi ◽  
Petteri Viramo ◽  
Tuomo Polvikoski ◽  
Katariina Kainulainen ◽  
...  
Keyword(s):  
Mini Mental State Examination ◽  
Mmse Score ◽  
Reference Population ◽  
Apo E ◽  
Diagnosis Of Dementia ◽  
Ε4 Allele ◽  
Very Old Age ◽  
The Mean ◽  
Apo E Genotype ◽  
State Examination

We examined 510 subjects representing 83.2% of all citizens of a Finnish city aged 85 years or over. Mini-Mental State Examination (MMSE) scores, diagnosis of dementia by DSM-III-R criteria, and Apo-E genotype were determined. The prevalence of dementia was 38.6%. The odds ratio (OR) of the Apo-E ε4 carriers (with the reference population of people with the genotype ε3/ε3) for dementia was 2.36 (95% CI 1.58–3.58). There was a significant sex difference: The OR in women was 3.23 (95% CI 2.02–5.17) whereas among men it was insignificant. The mean MMSE score (± SD) among the Apo-E ε4 carriers (15.0 ± 10.0) and noncarriers (18.7 ± 8.6) (p < .001) differed among the whole population, but not within the demented or nondemented subjects analyzed separately. This study does not support the hypothesis that the Apo-E ε4 allele impairs cognitive functions of nondemented elderly, at least in those surviving to very old age.

36 Cognitive functioning in patients aged 60 and older with chronic non- communicable diseases

2020 ◽  
Vol 91 (8) ◽  
pp. e23-e23
Author(s):  
¹Jurate Peceliuniene ◽  
²Guntis Karelis ◽  
³Irena Zukauskaite ◽  
Zane Kalnina ◽  
Diana Blagovescenska ◽  
...  
Keyword(s):  
Mini Mental State Examination ◽  
Cross Sectional Study ◽  
Communicable Diseases ◽  
Chi Square ◽  
Cross Sectional ◽  
Non Communicable Diseases ◽  
Cognitive Failures ◽  
Cognitive Failures Questionnaire ◽  
State Examination ◽  
One Way Anova

ObjectiveIt is well established that chronic non-communicable diseases (CND) are linked to early cognitive impairment (CI) before or at the beginning of the old age, bringing those patients at higher risk for dementia.The aim: to evaluate CI of aged 60 or older cognitively healthy patients visiting doctors due to different CNDMethods107 patients aged 60 or older (mean age 74 years; 44 male, 63 female; 25 were visiting general practitioner (GP), 21 – neurologist (NE), 23 – pulmonologist (PU), 38 – otorhinolaryngologist (OT)) for their CND took part in pilot cross sectional study. They filled The Cognitive Failures Questionnaire (CFQ), Subjective Cognitive Complaints (SCCs), Mini-Mental State Examination (MMSE). Results were compared using Pearson Chi-Square and one-way ANOVA.ResultsOT patients had higher CFQ results (M=30.7) comparing to all groups (GP M=24.3; NE M=22.6, PU M=18.3, p=0.001). PU patients had less problems with Forgetfulness (M=8.6), comparing to GP (M=11.4) or OT (M=12.4) groups (p=0.022). OT (M=9.3) had more problems with Distractibility comparing to PU (M=5.7) and GP (M=6.7) groups (p=0.011). OT had higher scores in False Triggering (M=7.9) comparing to GP (M=5.92), NE (M=5.8) and PU (4.8) groups (p=0.011).The cut-off point of row score 45 was overstepped in18.9% of OT group, 8% of GP group, but none in NE or PU group (p=0.026). Results of MMSE showed alike tendencies: PU patients (M=27.8) had higher results than GP (M=25.7) or OT (M=25.6) groups (p=0.029). CI was found in 39.1% of GP and 35.1% of OT, comparing to 19.0% in NE and 3.7% in PU groups (p=0.020). But groups did not differ by SCCs scores, even if 3 or more complains were found in 50.0% of GP, 52.2% of PU, 42.9% of NE and 71.1% OT groups. The only SCCs question where found differences between groups – limitation of daily activities: concerning about possible mistakes 62.5% of GP and PU groups would ask somebody’s help, while it would be done by 52.4% of NE and only 15.8% of OT group (p<0.001).ConclusionsCognitive health in elderly people with CND is not monitored well. About 2/3 of them have subjective cognitive complains (3 or more by SCCs), 1/4 would be named as having CI by MMSE, 8.5% have problems due to forgetfulness, distractibility, false triggering. Cognitive functions are predominantly impaired in OT group patients, however, they declare less need for helping them.

Reliable Individual Change Scores on the 3MS in Older Persons With Dementia: Results From the Canadian Study of Health and Aging

2001 ◽  
Vol 13 (S1) ◽  
pp. 71-78 ◽  
Author(s):  
José Andrés Correa ◽  
Anne Perrault ◽  
Christina Wolfson
Keyword(s):  
Older Persons ◽  
Mini Mental State Examination ◽  
Intraclass Correlation ◽  
Time Frame ◽  
Community Dwelling ◽  
Individual Change ◽  
Change Scores ◽  
Diagnosis Of Dementia ◽  
Severity Of Dementia ◽  
State Examination

We examined the degree of interrater agreement on the Modified Mini-Mental State Examination (3MS), administered both in the home and at the clinical examination, to determine the boundaries of reliable individual changes for 257 community-dwelling older persons who received a diagnosis of dementia at CSHA-1. Individual score differences were approximately normally distributed (mean of differences 0.2; SD 8.0; 95% confidence interval -16 to 16). The intraclass correlation coefficient was 0.85. Except for the language of testing, there was no relationship between score differences and the determinants investigated (i.e., age, education, type and severity of dementia). This study provides evidence that, in a time frame compatible with no change in cognition, the discrepancy between repeat 3MS scores can be as large as ± 16. These limits represent the range of variability consistent with no change and should be considered when interpreting individual change scores.

scholarly journals A Disease Modification Effect of APOEE4 on the Association between Urinary Albumin Excretion and Cognition in Korean Adults

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Min-Ho Shin ◽  
Sun-Seog Kweon ◽  
Jin-Su Choi ◽  
Young-Hoon Lee ◽  
Hae-Sung Nam ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Sex Education ◽  
Mini Mental State Examination ◽  
Cross Sectional Study ◽  
Urinary Albumin ◽  
Cross Sectional ◽  
Korean Adults ◽  
Educational Attainments ◽  
Modifying Effect ◽  
State Examination

Background. No previous study examined a disease modifying effect of APOEE4 status on the association between the urinary albumin-to-creatinine ratio (UACR) and cognition. This study aimed to investigate whether APOEE4 modified the association in Korean adults.Methods. We performed a cross-sectional study in adults aged 45 to 74 who were living in Namwon City, Republic of Korea. Cognitive function was measured with the Korean version of modified Mini-Mental State Examination (K-mMMSE) and cognitive impairment was defined as scores falling below the 25th percentile of the K-mMMSE according to age, sex, and educational attainments.Results. A total of 10,190 participants (4006 men and 6184 women) were analyzed in the present study. Of these, 1698 subjects (16.7%) were APOEE4 carriers. The UACR values were negatively associated with the K-mMMSE scores, even after adjusting for potential confounders including age, sex, education, and vascular risk factors. APOEE4 modified the association significantly, resulting in a steeper decline of cognitive function with the increase in UACR inE4 carriers (Pfor interaction = 0.021).Conclusion. Higher UACR values were significantly associated with cognitive dysfunction in the general Korean population, with cognition in APOEE4 carriers being more severely affected by increased UACR.

scholarly journals HUBUNGAN AKTIVITAS FISIK TERHADAP KUALITAS TIDUR DAN FUNGSI KOGNITIF PADA KELOMPOK LANSIA DHARMA SENTANA, BATUBULAN

2021 ◽  
Vol 17 (2) ◽  
pp. 110
Author(s):  
I Made Dhita Prianthara ◽  
I.A Pascha Paramurthi ◽  
I Putu Astrawan
Keyword(s):  
Quality Index ◽  
Mini Mental State Examination ◽  
Pittsburgh Sleep Quality Index ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Activity Scale ◽  
State Examination ◽  
Physical Activity Scale

Peningkatan jumlah populasi lansia menyebabkan semakin banyak masalah kesehatan yang akan dialami oleh lansia yang disebabkan karena kurangnya aktivitas fisik seperti gangguan kualitas tidur dan penurunan fungsi kognitif. Seiring dengan pertambahan usia dan berkurangnya aktivitas fisik, semakin besar kemungkinan seseorang mengalami gangguan kualitas tidur dan penurunan fungsi kognitif. Aktivitas fisik yang rutin dilakukan oleh lansia dapat mencegah terjadinya gangguan kualitas tidur dan mencegah penurunan fungsi kognitif. Semakin meningkat aktivitas fisik maka semakin meningkat kualitas tidur dan fungsi kognitif pada lansia. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara aktivitas fisik terhadap kualitas tidur dan fungsi kognitif pada kelompok lansia Dharma Sentana, Batubulan. Penelitian ini adalah cross sectional study dengan teknik pengambilan sampel purposive sampling. Penelitian dilakukan di kelompok lansia Dharma Sentana, Batubulan. Sampel penelitian ini berjumlah 50 orang lansia. Aktivitas fisik diukur dengan International Physical Activity Scale (IPAQ), kualitas tidur diukur dengan Pittsburgh Sleep Quality Index (PSQI), dan fungsi kognitif diukur dengan Mini-Mental State Examination (MMSE). Berdasarkan hasil uji chi-square didapatkan nilai p=0,007 yang artinya ada hubungan antara aktivitas fisik dengan kualitas tidur dan nilai p=0,000 yang artinya ada hubungan antara aktivitas fisik dengan fungsi kognitif. Simpulan penelitian ini adalah ada hubungan antara aktivitas fisik terhadap kualitas tidur dan fungsi kognitif pada kelompok lansia Dharma Sentana, Batubulan. Kata kunci: Lansia, Aktivitas Fisik, Kualitas Tidur, Fungsi Kognitif

scholarly journals Nutritional status, dementia, and mobility among nursing home’s residents: First exhaustive cross-sectional study in Limousin territory (France)

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250595
Author(s):  
Philippe Fayemendy ◽  
Gustave Mabiama ◽  
Thibault Vernier ◽  
Aude Massoulard-Gainant ◽  
Carole Villemonteix ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Mini Mental State Examination ◽  
Nutritional Assessment ◽  
Mini Nutritional Assessment ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mobility Patterns ◽  
Cross Sectional ◽  
Nutritional Data ◽  
State Examination

Background Aging is accompanied by a drop in the level of health and autonomy, within Western countries more and more people being cared for in nursing homes (NH). The nutritional data in NH in France remain poor, not exhaustive and not representative. The objective of the study was to assess the nutritional status, dementia and mobility patterns among residents of NH in the Limousin territory of France. Methods The study was cross-sectional, descriptive and exhaustive, conducted with the residents of 13 voluntary NH. Undernutrition was identified using French High Authority for Health criteria, and obesity if Body Mass Index >30, in the absence undernutrition criterion. The Mini Mental State examination scores was used for dementia assessment at the threshold of 24. The Mini Nutritional AssessmentTM was used for mobilitity assessment. The statistics were significant at the 5% threshold. Results 866 residents (70.6% women) included with an average age of 85.3 ± 9.3 years. Undernutrition was 27.5%, obesity 22.9%, dementia 45.7% and very low mobility 68.9%. Women were older than men, more often undernourished, more often demented and more often had very low mobility (p<0.01). Undernutrition (p<0.0001) and low mobility (p<0.0001) were significantly higher among those with dementia versus those without dementia. Very low mobility was higher among undernourished (p<0.05). Conclusions Undernutrition and obesity are important problems in NH in France. Being a woman, having dementia and having a very low mobility may induce undernutrition.

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