Abstract
Background Safe and effective vaccines became an important preventive tool to protect people against novel Corona Virus Disease infection. Since physicians are at higher risk for contagion of COVID-19 infection, they were prioritized for early vaccination. Also, they are role models who can improve adherence of people to vaccination. Aim of the study: to determine the acceptability of COVID-19 vaccines among physicians in the Gharbia governorate, Egypt. Methods: A cross-sectional study recruited working physicians through snowballing random sampling technique. Data was collected by using a self-administered electronic questionnaire which measured the self-perceived risk to COVID-19 infection, the attitudes and acceptance of COVID-19 vaccines. Results: The study enrolled 1268 physicians, 22% of them were vaccinated .Only 24% expressed their acceptance towards COVID-19 vaccines, while 36.7% didn't agree to get vaccinated. Vaccination unacceptance was significantly associated with increasing age, female gender, higher educational attainments, limited income, no direct patients' contact, diagnostic subspecialty, and working in a rural health facility (p= 0.004, 0.02, <0.0001, <0.0001, 0.01, 0.01, 0.002 respectively).Conclusions: Though physicians are at higher risk of infection, they had poor acceptance of COVID-19 vaccines which may, induce reluctance of people to get vaccinated. Special actions should be tailored to address the significant mediators associated with vaccine unacceptability.