scholarly journals Typhoid Vaccine in EPI; Relatively New Perhaps Overdue Strategy

2013 ◽  
Vol 33 (2) ◽  
pp. 152-154
Author(s):  
Sanjaya Dhakal ◽  
Ajaya Kumar Dhakal
Keyword(s):  
Low Income ◽  
Pathogenic Bacteria ◽  
Enteric Fever ◽  
Preventive Measure ◽  
Low Income Countries ◽  
Sewage Disposal ◽  
Expanded Program Of Immunization ◽  
High Prevalence ◽  
Improved Sanitation

Theoretically, it is possible to eliminate Salmonella, pathogenic bacteria that can cause a potentially fatal enteric fever. However, given the high prevalence of the disease in low-income countries that lack adequate facilities for sewage disposal and water treatment, and the fact that people can be long-term asymptomatic carriers, this goal is currently unrealistic. This levies constant need of a preventive measure to reduce morbidity and mortality in children associated with Typhoid Fever in endemic countries like Nepal. Currently, the best possible approach is to integrate the Typhoid vaccination into the Expanded Program of Immunization (EPI) until an improved sanitation and sewage disposal system is attained. We must acknowledge that this approach is not definitive until sufficient political and economic attention is received from all stakeholders. DOI: http://dx.doi.org/10.3126/jnps.v33i2.8715 J Nepal Paediatr Soc. 2013; 33(2):152-154

scholarly journals Will Households Invest in Safe Sanitation? Results from an Experimental Demand Trial in Nakuru, Kenya

2021 ◽  
Vol 18 (9) ◽  
pp. 4462
Author(s):  
Rachel Peletz ◽  
Caroline Delaire ◽  
Joan Kones ◽  
Clara MacLeod ◽  
Edinah Samuel ◽  
...  
Keyword(s):  
Low Income ◽  
Low Income Countries ◽  
Health Concern ◽  
High Quality ◽  
Market Prices ◽  
Price Point ◽  
Improved Sanitation ◽  
Sanitation Infrastructure ◽  
The City ◽  
Experimental Demand

Unsafe sanitation is an increasing public health concern for rapidly expanding cities in low-income countries. Understanding household demand for improved sanitation infrastructure is critical for planning effective sanitation investments. In this study, we compared the stated and revealed willingness to pay (WTP) for high-quality, pour-flush latrines among households in low-income areas in the city of Nakuru, Kenya. We found that stated WTP for high-quality, pour-flush latrines was much lower than market prices: less than 5% of households were willing to pay the full costs, which we estimated between 87,100–82,900 Kenyan Shillings (KES), or 871–829 USD. In addition, we found large discrepancies between stated and revealed WTP. For example, 90% of households stated that they would be willing to pay a discounted amount of 10,000 KES (100 USD) for a high-quality, pour-flush latrine, but only 10% of households redeemed vouchers at this price point (paid via six installment payments). Households reported that financial constraints (i.e., lack of cash, other spending priorities) were the main barriers to voucher redemption, even at highly discounted prices. Our results emphasize the importance of financial interventions that address the sizable gaps between the costs of sanitation products and customer demand among low-income populations.

scholarly journals Integrated photothermal decontamination device for N95 respirators

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marcelo Muñoz ◽  
Maxime Comtois-Bona ◽  
David Cortes ◽  
Cagla Eren Cimenci ◽  
Qiujiang Du ◽  
...  
Keyword(s):  
Low Income ◽  
Temperature Treatment ◽  
Low Income Countries ◽  
Effective Vaccine ◽  
Global Pandemic ◽  
Photothermal Treatment ◽  
Mild Temperature ◽  
N95 Respirators ◽  
Uv C

AbstractThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions. The COVID-19 pandemic has also resulted in a shortage of personal protective equipment (PPE) in many regions around the world, particularly in middle- and low-income countries. The shortages of PPE, such as N95 respirators, is something that will persist until an effective vaccine is made available. Thus, devices that while being easy to operate can also be rapidly deployed in health centers, and long-term residences without the need for major structural overhaul are instrumental to sustainably use N95 respirators. In this report, we present the design and validation of a decontamination device that combines UV-C & B irradiation with mild-temperature treatment. The device can decontaminate up to 20 masks in a cycle of < 30 min. The decontamination process did not damage or reduce the filtering capacity of the masks. Further, the efficacy of the device to eliminate microbes and viruses from the masks was also evaluated. The photothermal treatment of our device was capable of eradicating > 99.9999% of the bacteria and > 99.99% of the virus tested.

scholarly journals Position of Scientific Oncological Societies Towards Biosimilar Antibodies

Breast Care ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 5-8 ◽  
Author(s):  
Bernhard Wörmann ◽  
Marianne Sinn
Keyword(s):  
Monoclonal Antibodies ◽  
Low Income ◽  
Financial Burden ◽  
Informed Consent Process ◽  
Low Income Countries ◽  
Efficacy And Safety ◽  
Economic Competition ◽  
Off Label ◽  
Careful Documentation

First biosimilars of monoclonal antibodies have recently been approved in oncology. Biosimilars enable economic competition, alleviate the financial burden for insurances, and may facilitate access to these drugs in low-income countries. Biosimilars are not completely identical to the original drug. The approval of biosimilars is only partially based on results of randomized clinical studies. In the introduction phase of new biosimilars, this can lead to uncertainties for patients and physicians. Based on the current clinical data and experiences, biosimilars of monoclonal antibodies in oncology show no significant differences in pharmacokinetics, efficacy, and safety in comparison to the patented originals. Scientific medical societies recommend the use of biosimilar monoclonal antibodies and support switching in long-term treatments. However, the use of biosimilars for off-label indications requires additional attention towards efficacy and safety. Active counselling of the patient by the treating physician is the most important step in the informed consent process, especially when switching from an original to a biosimilar. Careful documentation of the prescribed drug and enhanced pharmacovigilance are recommended for the use of biosimilars.

scholarly journals Availability of ENT Surgical Procedures and Medication in Low-Income Nation Hospitals: Cause for Concern in Zambia

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Lufunda Lukama ◽  
Chester Kalinda ◽  
Warren Kuhn ◽  
Colleen Aldous
Keyword(s):  
Surgical Procedures ◽  
Low Income ◽  
Care Delivery ◽  
National Policy ◽  
Low Income Countries ◽  
Health Concern ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Essential Drugs ◽  
High Prevalence

Background. Ear, nose, and throat (ENT) diseases are an oft overlooked global health concern. Despite their high prevalence and associated morbidity and mortality, ENT diseases have remained neglected in health care delivery. In Zambia and many other low-income countries, ENT services are characterized by poor funding, unavailable surgical procedures, and erratic supply of essential drugs. Objective. To investigate ENT service provision in Zambia with regard to availability of surgical procedures and supply of essential drugs. Methods. A descriptive cross-sectional survey was conducted using a piloted structured questionnaire between 17 January 2017 and 2 January 2018. Included in the study were the 109 hospitals registered with the Ministry of Health (MoH) across the 10 provinces of Zambia. Results. Of the participating hospitals, only 5.9% (n=1) and 40% (n=2) of Second-Level Hospitals (SLH) and Third-Level Hospitals (TLH), respectively, carried out tympanoplasty, myringotomy, and grommet insertion (M+G). Frontal trephination and external ethmoidectomy were offered in 11.7% (n=2) and 40% (n=2) of SLH and TLH, respectively. While tracheostomy (39.3%, n=24), tonsillectomy (27.9%, n=17), and adenoidectomy (27.9%, n=17) were the most widely performed head and neck procedures, laryngectomy was carried out by 1 hospital. Between 14.8% (n=9) and 36.1% (n=22) of hospitals lacked antibiotic and/or antiseptic ear drops. Despite 96.7% (n=59) of the respondents acknowledging ENT as an important branch of clinical practice, only 15.3% (n=4) of the hospitals had a budget for ENT. Also, 6.6% (n=4) of the respondents thought the discipline of ENT had received enough attention. Conclusion. ENT service delivery in Zambia is limited with regard to performed surgical procedures and availability of essential drugs, necessitating urgent intervention. The findings from this study may be used to direct national policy on the improvement of provision of ENT services in Zambia.

scholarly journals Reversible Long Term Contraceptives Utilization among Married Women of Reproductive Age Group in Areka Town, Southern Ethiopia

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Samson Kastro Dake ◽  
Temesgen Lera Abiso
Keyword(s):  
Low Income ◽  
Statistical Significance ◽  
Married Women ◽  
Reproductive Age ◽  
Low Income Countries ◽  
Southern Ethiopia ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Reproductive Age Group

BACKGROUND፡ In low income countries, bearing many children is the main factor affecting maternal health. This study aimed to estimate the prevalence of reversible long term contraceptives utilization and identify factors associated with it among married women of child bearing age in Areka District in South EthiopiaMETHODS: We conducted a community-based cross-sectional survey involving systematically recruited 346 married women of reproductive age group. Data was collected using a structured interviewer-administered questionnaire on May 2019. We used SPSS version 25 for data entry and analyses. Bivariate logistic regression analysis was used to select exposure variables with crude association. Multivariate analysis was done to control for potential confounders and identify predictors of the outcome. Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI)was reported, and statistical significance was declared at p<0.05.RESULTS: The prevalence of reversible long term contraceptives utilization among married women of reproductive age group was 134(38.7%). Utilization of Reversible Long Term Contraceptives (RLTCs) was positively associated with being protestant Christian religion follower, advanced educational status, history of abortion, and having a better attitude towards reversible long term contraceptives. In other words, being housewife, being daily laborer, having no radio in the household and making fertility decisions alone were negatively associated.CONCLUSION: The prevalence of RLTCs in the study area was high. Women should be empowered educationally through other alternative opportunities to formal school. In addition to electronic media, different community events and community conversations should be used to convey messages on contraceptives particularly RLTCs. Behavioral change communications would benefit women in shaping their attitudestowards RLTCs.

scholarly journals Is physiotherapy an underused approach to prevent surgery in selective musculoskeletal disorders?

2021 ◽  
Vol 20 (2) ◽  
pp. 409-413
Author(s):  
Junaid Amin ◽  
Sameer Gohir ◽  
Umer Qaiser ◽  
Ammar A Siddiqui ◽  
Freah Alshammary ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Musculoskeletal Disorders ◽  
Low Income ◽  
Medical Science ◽  
Low Income Countries ◽  
Long Term Outcomes ◽  
Physiotherapy Intervention ◽  
Musculoskeletal Problems ◽  
The Cost

Objectives: The purpose of the literature review was to appraise the evidence that an early physiotherapy intervention helps to prevent the surgery in selective musculoskeletal disorders. A search of Google Scholar, Web of Science, Scopus, and PubMed was carried out utilizing the terms (“physiotherapy”, “surgery” OR “exercise, surgery” OR “rehabilitation”, “surgery”). Methods: The article titles and abstracts were screened for eligibility and included in the review. The recent literature evidently emphasized that physiotherapy has opted in selective musculoskeletal problems to avoid and delay surgeries. Results: Regardless of recommended conservative treatment option and effectiveness of physiotherapy, a massive gap can be observed between its evidence and practice. Conversely, overuse of diagnostic imaging, surgeries, and medications is present in clinical practice. In most of the clinical problems the long-term outcomes were reported the same with surgical and physiotherapy intervention. Likewise, patients can also get the advantage of better clinical outcome and cost-effectiveness with physiotherapy as compared to surgical intervention. Conclusion: The cost-effectiveness is an important factor in low-income countries where economic aspects of health care are highly considered. These advantages of physiotherapy should be considered by the clinicians, policymakers, patients, and included in the clinical guidelines. Bangladesh Journal of Medical Science Vol.20(2) 2021 p.409-413

scholarly journals Reversible Long Term Contraceptives Utilization among Married Women of Reproductive Age Group in Areka town, South Ethiopia

2020 ◽  
Author(s):  
Samson Kastro Dake ◽  
Temesgen Lera
Keyword(s):  
Low Income ◽  
Statistical Significance ◽  
Married Women ◽  
Reproductive Age ◽  
Low Income Countries ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
South Ethiopia ◽  
Reproductive Age Group

Abstract Background: In low income countries, maternal mortality rate remains high. Bearing many children is the main factor affecting maternal health. This study aimed to estimate the prevalence of reversible long term contraceptives utilization and identify factors associated with it among married women of child bearing age in Areka town in South Ethiopia Methods: We did a community-based cross-sectional survey involving systematically recruited 346 married women of reproductive age group. Data was collected using a structured interviewer-administered questionnaire on May 2019. We used SPSS version 25 for data entry and analyses. Bivariate logistic regression analysis was used to select exposure variables with a crude association. Multivariate analysis was done to control for potential confounders and identify predictors of the outcome. Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) was reported and statistical significance was declared at p <0.05.Results: The prevalence of reversible long term contraceptives utilization among married women of reproductive age group was 38.7% in the study area. Utilization of reversible long term contraceptives was positively associated with being Protestant Christian religion follower (AOR=5.33; 95% CI: 1.63, 17.40), advanced educational status (AOR=5.78; 95% CI: 1.97, 17.02), history of abortion (AOR=7.17; 95% CI: 2.81, 18.27), and having a better attitude towards reversible long term contraceptives (AOR=2.85; 95% CI: 1.46, 5.57). Whereas, being a housewife (AOR=.27; 95% CI: .09, .79) and daily laborer (AOR=.14; 95% CI: .02, .80), having no radio in the household (AOR=.40; 95% CI: .16, .99) and making fertility decisions alone (AOR=.12; 95% CI: .04, .37) were negatively associated. Conclusion: Women should be empowered educationally through other alternative opportunities to school. On top of electronic media, other alternative media should be used to convey messages on contraceptives particularly RLTCs. Behavioral change communications would benefit women in shaping their attitudes towards RLTCs.

scholarly journals THE NATURE OF INNOVATION ECO-SYSTEM OF THE WESTERN KAZAKH STATE UNIVERSITY

2020 ◽  
Vol 9 (4) ◽  
pp. 254
Author(s):  
Liliya Mergaliyeva
Keyword(s):  
Higher Education ◽  
Low Income ◽  
Low Income Countries ◽  
State University ◽  
Education Development ◽  
Frugal Innovation ◽  
Innovation Culture ◽  
New Business ◽  
The University

It was a strong belief that higher education institutions are notoriously resistant to change. However, during the COVID-19 pandemic, universities have quickly and effectively moved millions of students and educators online despite huge logistical and technological challenges. There are very few industries that have reacted in this way. In future leading universities will look for a new business model and apply disruptive innovations into the leaning process.Today is a right time for planning a long term innovation strategy. In recent years Kazakh higher education development has been accompanied by intensive economic growth and raising demand for high qualifies employers. The aim of this research is to reveal the ways of implementing high innovation and creativity approach in universities under example of Western Kazakhstan State University. This study examines the factors determining conditions for development of innovation culture across the university and industry. The methodology is based on expert interviews, reflective experiences; surveying research for innovation, incorporating the information on innovation landscape map, university infrastructure, human resources, PESTEL analysis as well as industry overview. The results show that WKSU needs frugal innovation, as it provides a new entrepreneurial landscape for companies in low-income countries with limited resources to develop innovations.

scholarly journals Norovirus Infections and Disease in Lower‐Middleand Low‐Income Countries, 1997–2018

Viruses ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 341 ◽  
Author(s):  
Mans
Keyword(s):  
Low Income ◽  
Low Income Countries ◽  
Viral Gastroenteritis ◽  
Healthy Controls ◽  
Limited Data ◽  
Middle Income ◽  
Predominant Genotype ◽  
Middle Income Countries ◽  
High Prevalence ◽  
Polymerase Chain

Noroviruses are a major cause of viral gastroenteritis. The burden of the norovirus in lowresourcesettings is not well‐established due to limited data. This study reviews the norovirusprevalence, epidemiology, and genotype diversity in lower‐middle‐income countries (LMIC) andin low‐income countries (LIC). PubMed was searched up to 14 January 2019 for norovirus studiesfrom all LIC and LMIC (World Bank Classification). Studies that tested gastroenteritis cases and/orasymptomatic controls for norovirus by reverse transcription‐polymerase chain reaction (RT‐PCR)were included. Sixty‐four studies, the majority on children <5 years of age, were identified, and 14%(95% confidence interval; CI 14–15, 5158/36,288) of the gastroenteritis patients and 8% (95% CI 7–9,423/5310) of healthy controls tested positive for norovirus. In LMIC, norovirus was detected in 15%(95% CI 15–16) of cases and 8% (95% CI 8–10) of healthy controls. In LIC, 11% (95% CI 10–12) ofsymptomatic cases and 9% (95% CI 8–10) of asymptomatic controls were norovirus positive.Norovirus genogroup II predominated overall. GII.4 was the predominant genotype in all settings,followed by GII.3 and GII.6. The most prevalent GI strain was GI.3. Norovirus causes a significantamount of gastroenteritis in low‐resource countries, albeit with high levels of asymptomaticinfection in LIC and a high prevalence of coinfections

Reaping the Dividends of Globalization: A Winning Road Map

2019 ◽  
pp. 254-309
Author(s):  
Justin Yifu Lin ◽  
Célestin Monga
Keyword(s):  
Low Income ◽  
World Trade ◽  
Low Income Countries ◽  
Global Trade ◽  
Poor Countries ◽  
Road Map ◽  
Industrial Parks ◽  
Long Term Trends ◽  
Economic Zones

This chapter analyzes the conditions needed to design and implement successful special economic zones and industrial parks. It discusses long-term trends and fundamental issues in global trade since trade is the main source of growth for low-income countries that have limited domestic demand. In recent years the story of global trade has often been presented by some economists and development experts as a cause for concern on the export-led growth model that made possible the so-called Asian Miracle that is no longer available for poor countries in Africa or South Asia. But statistics appear to show a turning tide: the value of world merchandise exports rose from $2.03 trillion in 1980 to $18.26 trillion in 2011, equivalent to 7.3 percent growth per year on average in current dollar terms according to WTO trade statistics. But from 2012 to 2014, world trade growth averaged only 2.2 percent, well below the average for the proceeding 20-year period. This has raised the question whether the same shaping factors that have given rise to today's global trade system are likely to continue in the medium and long term.

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