scholarly journals Breakthrough infection after Covishield COVID-19 vaccine among health care workers at Patan Academy of Health Sciences, Nepal

2021 ◽  
Vol 8 (2) ◽  
pp. 10-17
Author(s):  
Jay Shah ◽  
Priscilla Samson ◽  
Nabees MS Pradhan ◽  
Ashis Shrestha ◽  
Shreekrishna Maharjan ◽  
...  

Introduction: Coronavirus Disease 2019 (COVID-19) vaccines have an important role in the control and prevention of the pandemic. However, infection after vaccination, though uncommon, has been reported after partial or complete immunization. This study aims to find out vaccine breakthrough infection after the Covishield COVID-19 vaccine. Method: This cross-sectional survey was conducted among the health care workers (HCWs) from May 2021 to July 2021 at Patan Hospital, Patan Academy of Health Sciences, Nepal who received the Covishield vaccine. The data were collected using Google form and a printed questionnaire on COVID 19 breakthrough infection ≥2w after vaccination. The rate of breakthrough infection, hospitalization, and its association with age, gender, and working departments of HCWs was analyzed using SPSS. Ethical approval was obtained. Result: Out of 1462 HCWs approached, 880 completed the survey, among which 819 (93.1%) had a completed vaccination status. Infection after the first and before the second dose was 164 (18.7% of 880) and after two doses 131 (16%). The breakthrough infection occurred in 83 (10.1% of 819). There was no statistically significant association of breakthrough infection with age, gender, and working department of HCWs. Total 74 (8.4%) were managed by admission in hospital. Conclusion: The findings of this study reveal a low breakthrough infection rate after Covishield vaccination among HCWs at Patan Academy of Health Sciences, Kathmandu, Nepal. Overall, COVID-19 infection rates decreased after the first and second dose of the vaccine.

Author(s):  
Hasan S. Alamri ◽  
Wesam F. Mousa ◽  
Abdullah Algarni ◽  
Shehata F. Megahid ◽  
Ali Al Bshabshe ◽  
...  

Objective: Little is known about the impact of Coronavirus (COVID-19) among the health care workers in Saudi Arabia. Therefore, the present study aimed to assess the psychological impact of COVID-19 among the health care workers. Methods: A cross-sectional survey was conducted from May till mid-July among 389 health care workers from government and private hospitals in Saudi Arabia. Data was collected using a pre-structured online questionnaire that measured adverse psychological outcomes, including the Patient Health Questionnaire-9 (PHQ-9) scale and the Generalized Anxiety Disorder 7-item (GAD-7) scale. The Pearson chi-square test was used to assess the distribution of depression and anxiety among health care workers. Results: A high level of anxiety was recorded among the health care workers, and 69.3% of health care workers below the age of 40 were found to have depression. There was a significant increase in depression among staff with chronic health problems (72.1% vs. 61.9%; p = 0.048). High anxiety levels were detected among young staff compared to others (68.7% vs. 43.8%; p = 0.001). Moreover, 82.1% of the female staff were anxious, as compared to 55.6% of the males (p = 0.001). Conclusions: We found increased prevalence of adverse psychological outcomes among the health care workers in Saudi Arabia during the outbreak of COVID-19. Therefore, there is a need for proper screening and development of corresponding preventive measures to decrease the adverse psychological outcomes.


2021 ◽  
Vol 09 (01) ◽  
pp. 18-30
Author(s):  
Chika A. Okoro ◽  
Eridiong O. Onyenweaku ◽  
Emecheta G. Okwudire ◽  
Muriel K. Kalu ◽  
Oluremilekun C. Kusimo ◽  
...  

Author(s):  
Mohamed Khalis ◽  
Asmaa Hatim ◽  
Latifa Elmouden ◽  
Mory Diakite ◽  
Abdelghafour Marfak ◽  
...  

Author(s):  
Nicola Magnavita ◽  
Giovanni Tripepi ◽  
Reparata Rosa Di Prinzio

In March–April 2020, the Corona Virus Disease 19 (COVID-19) pandemic suddenly hit Italian healthcare facilities and in some of them many staff members became infected. In this work 595 health care workers from a public company were tested for Severe acute respiratory syndrome coronavirus 2 (82 positive) and asked to complete a questionnaire on early COVID-19 symptoms. Respiratory symptoms were present in 56.1% of cases. Anosmia and dysgeusia in COVID-19 cases were found to have an odds ratio (OR) = 100.7 (95% Confidence Interval [CI] = 26.5–382.6) and an OR = 51.8 (95%CI 16.6–161.9), respectively. About one in three of the cases (29.3%) never manifested symptoms. Anxiety was reported by 16.6% of COVID-19 cases and depression by 20.3%, with a significant increase in the estimated risk (OR = 4.3; 95%CI = 2.4–7.4 for anxiety, OR = 3.5; 95%CI = 2.0–6.0 for depression). In cases, sleep was a significant moderating factor in the relationship between occupational stress, or organizational justice, and anxiety. The early diagnosis of COVID-19 in health care workers, must consider, in addition to respiratory disorders and fever, anosmia, dysgeusia, exhaustion, myalgias and enteric disorders. The frequency of anxiety and depression disorders in the population examined was not higher than that commonly recorded in the same company during periodic checks in the years preceding the epidemic. In COVID-19 cases there was a significant risk of anxiety, especially in those who had low sleep quality. Mental health support and improvement interventions must mainly concern workers with positive tests and should also tend to improve sleep quality.


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