scholarly journals Status of Thyroid Function among Patients of National Medical College and Teaching Hospital

Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 64-70
Author(s):  
Anup Shamsher Budhathoki ◽  
Suprita Gupta ◽  
Sanjay Kumar Sah ◽  
Navin Kumar Sah ◽  
Navin Kumar Sah ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Teaching Hospital ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Overt Hypothyroidism ◽  
Central Laboratory ◽  
National Medical College ◽  
Medical College ◽  
National Medical ◽  
High Prevalence

Background: Thyroid dysfunction is one of the most common endocrinopathies after Diabetes Mellitus. Thyroid dysfunction is defined as the alteration in Thyroid Stimulating Hormone (TSH) with normal or abnormal thyroid hormones. Nepalese population have a high risk for thyroid dysfunction with a high prevalence of iodine deficiency. Objective: To study the prevalence of thyroid dysfunction among the patients visiting National Medical College, Birgunj, Nepal for checkup and suggested to assess thyroid function. Materials and Methods: The hospital-based study was conducted in Central Laboratory, National Medical College and Teaching Hospital (NMCTH), Birgunj in collaboration with the Department of Biochemistry. Total 7040 patients visiting Central Laboratory for thyroid function assessment were included in the study between July 2017 to December 2019. The venous blood sample was collected and serum-free triiodothyronine(fT3), free tetraiodothyronine(fT4) and thyroid stimulating hormone (TSH) was estimated by Chemiluminescence Immunoassay (CLIA) method using Access 2 Beckman Coulter analyser. (Beckman Coulter Inc., California, USA). Results: Among 7040 subjects under study, 2138(30%) were found to have thyroid dysfunction with 13% having subclinical hypothyroidism, about 8% of overt hypothyroidism, about 4% with subclinical hyperthyroidism and 5% with overt hyperthyroidism. Majority of the thyroid dysfunction study group belonged to the 16-30 years age group followed by 31-45 years. Mean±SE for TSH, fT4 and fT3 levels show statistically significant differences in different thyroid disorders. Conclusion: The study revealed a high prevalence of subclinical hypothyroidism followed by overt hypothyroidism among the patients visiting National Medical College and Teaching Hospital, Birgunj, Nepal. A higher percentage of females were found to have thyroid dysfunction compared to male.

scholarly journals Menstrual disorders associated with thyroid dysfunction

2017 ◽  
Vol 6 (11) ◽  
pp. 5113
Author(s):  
Ramya M. R. ◽  
. Parvathavarthini ◽  
Darshan Savery ◽  
R. Sankareswari
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Cost Effective ◽  
Thyroid Stimulating Hormone ◽  
Reproductive Age ◽  
Function Evaluation ◽  
Medical College ◽  
Normal Thyroid Function ◽  
High Prevalence ◽  
Menstrual Patterns

Background: Present study was done to evaluate the thyroid function in patients presenting with varying menstrual patterns of reproductive age group from 15 to 45 years of age.Methods: This prospective study was carried out in obstetrics and gynecology Department of Sri Venkateshwaraa Medical College, Pondicherry, India on 155 women, clinically given the provisional diagnosis of dysfunctional uterine bleeding (DUB). All these patients were investigated for T3, T4, TSH (Thyroid stimulating hormone) levels and grouped according to that.Results: Among the 155 women (58.7%) were normal thyroid function, (41.3%) had hypothyroid and (1.3%) had subclinical hypothyroidism.Conclusions: There is a high prevalence of thyroid disorders in cases which are clinically diagnosed as DUB. Evaluating for thyroid and treating it medically which was most accurate and cost effective and unnecessary surgery was avoided. Hence the thyroid function evaluation should be mandatory in cases of DUB to detect thyroid dysfunction and these cases should be referred to physician for further medical treatment.

scholarly journals Association between ultrasonography echogenicity and heterogeneity and thyroid function in autoimmune diffuse thyroid diseases in children and adolescents 

2021 ◽  
Author(s):  
Ji Eun Park ◽  
Sook Min Hwang ◽  
Ji-Young Hwang ◽  
Jin Hee Moon ◽  
Ik Yang ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Diseases ◽  
Overt Hypothyroidism ◽  
Thyroid Ultrasound ◽  
Thyroid Status ◽  
Children And Adolescent ◽  
Overt Hyperthyroidism

Abstract Purpose: To evaluate the association between thyroid echogenicity and heterogeneity seen on ultrasonography (US) and thyroid function in pediatric and adolescent populations with autoimmune diffuse thyroid diseases (AITD).Methods: From 2000 to 2020, we reviewed thyroid ultrasound (US) images and thyroid function statuses in 133 children and adolescent AITD patients. Our review of the images focused on decreased echogenicity and heterogeneity, which were classified into four grades.Results: Among patients with overt hypothyroidism or overt hyperthyroidism, 94.2% (65/69) showed a US grade of 3 or 4. In patients with subclinical hyper/hypothyroidism or euthyroidism, 45.3% (29/64) showed grades 1 or 2. There were no overt hyper/hypothyroidism patients with US grade 1. When we compared US grades according to thyroid status, more severe thyroid dysfunction was significantly associated with higher US grade (p=0.047). Thyroid stimulating hormone (TSH) level differed significantly according to US grades when we evaluated hyperthyroid (p=0.035) and hypothyroid (p=0.027) states independently. 11 patients showed both US grade and thyroid function status changes on follow-up US.Conclusions: In children and adolescent AITD patients, there was an association between decreased echogenicity and heterogeneity on US and thyroid dysfunction.

scholarly journals Prevalence of Pulmonary Tuberculosis among the suspected patients visiting tertiary care hospital in Birgunj, Nepal

2013 ◽  
Vol 1 (1) ◽  
pp. 48-52
Author(s):  
S Shrestha ◽  
B Shakya ◽  
P Shrestha
Keyword(s):  
Pulmonary Tuberculosis ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
College Teaching ◽  
High Morbidity ◽  
Major Public Health Problem ◽  
Care Hospital ◽  
National Medical College ◽  
Medical College ◽  
National Medical

Background and Objectives: Mycobacterial disease continues to cause high morbidity and mortality and is a major public health problem in Nepal. Bacteriological examination of sputum is the cornerstone in the diagnosis of pulmonary tuberculosis in the developing world. This prospective study was carried out with an objective to evaluate the prevalence of pulmonary tuberculosis among the patients visiting National Medical College Teaching Hospital by Ziehl- Neelsen (Zn) staining microscopy. Material and Methods: The study was cross-sectional study. Three consecutive early morning sputum collected from 626 patients were subjected to Zn staining and observed under oil immersion. Results: Among 626 patients, 85 (13.57%) were found to be Acid fast positive by Zn staining microscopy. Of total suspected patients,16.0% of male and 8.7% of female were infected, common among 41-60 years group (17.2%) followed by 21-40 years (12.6%) and multibacillary cases was 71.8%. Conclusion: The prevalence of pulmonary tuberculosis among National medical college teaching hospital was found to be higher than the Nation pulmonary tuberculosis detection rate, most commonly infecting males. DOI: http://dx.doi.org/10.3126/jmcjms.v1i1.7886 Janaki Medical College Journal of Medical Sciences (2013) Vol. 1 (1):48-52

scholarly journals Thyroid dysfunction in preeclampsia and related fetomaternal outcomes

2019 ◽  
Vol 8 (5) ◽  
pp. 1928
Author(s):  
Puja Banik ◽  
R. K. Praneshwari Devi ◽  
Aheibam Bidya ◽  
Akoijam Tamphasana ◽  
M. Agalya ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Birth Asphyxia ◽  
Normal Pregnancy ◽  
Thyroid Stimulating Hormone ◽  
Severe Preeclampsia ◽  
Intrauterine Fetal Death ◽  
Overt Hypothyroidism ◽  
Thyroid Function Tests ◽  
Cross Sectional

Background: Changes in thyroid function in normal pregnancy are well-documented but in complicated pregnancy like preeclampsia, very little is known. Studies have shown evidences of hypothyroidism in preeclampsia necessitating thyroid function tests to be done in preeclampsia. The study was done to analyze the fetomaternal outcome of preeclampsia with coexisting thyroid dysfunction.Methods: A cross-sectional analytical study was done over 18 months on 95 preeclamptic patients admitted at the antenatal ward and fetomaternal outcomes were analyzed according to thyroid status.Results: Out of 95 patients with preeclampsia, 42 (44.2%) had thyroid dysfunction. Among these 42 patients, 37 (38.9%) patients had subclinical hypothyroidism, 4 (4.2%) had overt hypothyroidism and 1 (1%) had hyperthyroidism. Severe preeclampsia was seen in 64.3% of the patients with thyroid dysfunction compared with 39.6% in euthyroid patients. The mean thyroid stimulating hormone (TSH) level was significantly higher and means free thyroxine (fT4) level was significantly lower in severe preeclampsia compared with non-severe preeclampsia. Complications like abruption, intrauterine fetal death (IUD), intrauterine growth restriction (IUGR), oligohydramnios, preterm deliveries, postpartum hemorrhage (PPH), low birth weight babies, birth asphyxia in babies and subsequent neonatal intensive care unit (NICU) admissions were significantly higher (p <0.05) in the preeclampsia patients with thyroid dysfunction in comparison with euthyroid ones.Conclusions: Hypothyroidism may be a modifiable risk factor for preeclampsia. Thyroid screening early in pregnancy may be helpful in predicting the occurrence of preeclampsia and timely thyroid hormone administration can reduce the maternal and perinatal morbidity and mortality associated with preeclampsia.

scholarly journals Obesity and hypothyroidism

2013 ◽  
Vol 10 (2) ◽  
pp. 54-58 ◽  
Author(s):  
S M Zakharova ◽  
L V Savelieva ◽  
M I Fadeeva
Keyword(s):  
Weight Loss ◽  
Energy Expenditure ◽  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Overt Hypothyroidism ◽  
Obese Patients ◽  
Common Diseases ◽  
The Relationship ◽  
Stimulating Hormone

Obesity and hypothyroidism are common diseases, and consequently clinicians should be particularly alert to the possibility of thyroid dysfunction in obese patients. The relationship between thyroid function and obesity is likely to be bidirectional, with hypothyroidism affecting weight, but obesity also influencing thyroid function. Both serum thyroid-stimulating hormone and fT3 are typically increased in obese individuals, an effect likely mediated by leptin. Following L-T4 treatment for overt hypothyroidism, weight loss appears to be modest and mediated primarily by loss of water weight rather than fat. Selected thyroid analogs might be a means by which to improve weight loss by increasing energy expenditure in obese patients during continued caloric deprivation

scholarly journals Prevalence of Thyroid Dysfunction and its Relationship with Severity of Depression among Patients of Depression attending Tertiary Hospital

2020 ◽  
Vol 16 (3) ◽  
Author(s):  
Arati Thapa ◽  
Mukesh Karki ◽  
Aradhana Thapa
Keyword(s):  
Teaching Hospital ◽  
Thyroid Dysfunction ◽  
Severity Of Illness ◽  
Tertiary Hospital ◽  
Overt Hypothyroidism ◽  
Medical Sciences ◽  
High Prevalence ◽  
Icd 10 ◽  
Severity Of Depression ◽  
Depressive Patients

Background: Thyroid dysfunction is common feature among patients presenting with depression. The aim of this study was to estimate the prevalence of thyroid dysfunction in patients with depression attending Psychiatry outpatient department of College of Medical Sciences and Teaching Hospital, Chitwan, Nepal and to investigate its relationship with the severity of depression. Methods: A total of 259 who attended the Psychiatry OPD of College of Medical Sciences and Teaching Hospital were enrolled over a period of 6 months after taking informed written consent. These patients were diagnosed as depression as per the ICD-10/ DCR criteria. The severity of illness was determined by using HAM-D. Thyroid profiling was done against common thyroid hormones TSH, FT3 and FT4 by standard method. Data was analyzed using SPSS. Results: Among 259 patients, thirty patients (18.40%) were found to have thyroid dysfunction, sub-clinical hypothyroidism was seen in 23 (14.1%) followed by 3.1% with overt hypothyroidism and 1.2% with overt  hyperthyroidism. However, there was no significant association found between severity of depression and thyroid dysfunction. Conclusions: This study concluded that there was high prevalence of thyroid dysfunction in patients with major depression. Thus screening of thyroid test among depressive patients may be helpful in proper management of cases.

scholarly journals Pattern of Thyroid Dysfunction in Women with Menstrual Disorders

2016 ◽  
Vol 2 (1) ◽  
pp. 3-6
Author(s):  
Saroj Khatiwada ◽  
Sharad Gautam ◽  
Rajendra KC ◽  
Shruti Singh ◽  
Shrijana Shrestha ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Overt Hypothyroidism ◽  
Endocrine Disorders ◽  
Thyroid Disorder ◽  
Menstrual Disorders ◽  
Free Triiodothyronine ◽  
Menstrual Disorder

BACKGROUNDThyroid disorders are among the commonest endocrine disorders worldwide. Thyroid dysfunction can interfere in multiple metabolic and physiological processes including menstrual cycle. This study was conducted to find pattern of thyroid dysfunction among women with menstrual disorders.METHODSTwo hundred thirty three females with menstrual disorders were screened for thyroid dysfunction. Thyroid function was assessed by measuring serum free triiodothyronine (T3), free thyroxine (T4) and thyroid stimulating hormone (TSH) levels.RESULTSThe mean age of study patients was 25.7±6.8 years. The most common menstrual disorder observed was irregular cycle (72.5%, n=169) followed by amenorrhea (21.9%, n=51) and menorrhagia (5.6%, n=13). Most of the patients were in the age group 15-24 years (51.1%, n=119), followed by 25-34 years (36.1%, n=84) and 35-45 years (12.9%, n=30). Mean level of free T3 and T4 was 2.91±1.05 pg/ml, 1.42±0.57 ng/dl respectively. Median TSH was 2.0 mIU/L (IQR, 1.0-4.0). Thyroid dysfunction was seen in 25.8% (n=60) women. Most common thyroid dysfunction was subclinical hypothyroidism (14.2%, n=33) followed by subclinical hyperthyroidism (6.9%, n=16), overt hyperthyroidism (3%, n=7) and overt hypothyroidism (1.7%, n=4).CONCLUSIONSThe study finds thyroid dysfunction especially subclinical hypothyroidism to be common among women with menstrual disorders. Thus, it may be beneficial to screen menstrual disorder patients for thyroid function especially to rule out thyroid disorder as potential etiological agent for menstrual disturbance.

scholarly journals Demographic Analysis of Adult Patients Presenting With Unilateral Ear Discharge at National Medical College

Med Phoenix ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 48-51
Author(s):  
Amit Jha
Keyword(s):  
Otitis Media ◽  
Teaching Hospital ◽  
Care Center ◽  
Tertiary Care ◽  
Chronic Otitis Media ◽  
Adult Patients ◽  
Common Symptom ◽  
National Medical College ◽  
Medical College ◽  
National Medical

Background: Discharging ear is a common symptom among the patients presenting in ENT OPD for consultation. The commonest cause for discharging ear is chronic otitis media. Poverty, ignorance, crowded living conditions due to large families, poor sanitation, and lack of personal and environmental hygiene are some of the main factors behind the prevalence of chronic otitis media. National medical college and teaching hospital is a tertiary care center located in Birgunj metropolitan city in central Nepal. It caters to thousands of patients with discharging ear each year.Methods: This qualitative, descriptive study was carried out in department of ENT-HNS at National Medical College and Teaching Hospital located Birgunj-15, Parsa, Province no. 2 of Nepal for duration of one year from August 1, 2014 to July 30, 2015. Two hundred and five (205) adult patients with complains of unilateral          discharging ear were included in the study.Results: Mostly female patients and those in the age group of 15-30 years from Bara and Parsa districts of Nepal including the areas around the Indo-Nepal border avail the services of department of ENT-HNS of National medical college and teaching hospital.Conclusions: The delivery of ENT-HNS services to the concerned patients is insufficient and inefficient owning to various factors. The government of Nepal and India along with National medical college and teaching hospital can work together to improve the situation. Med Phoenix. Vol. 3, Issue. 1, 2018, Page: 48-51 

scholarly journals The relationship between ultrasound findings and thyroid function in children and adolescent autoimmune diffuse thyroid diseases

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ji Eun Park ◽  
Sook Min Hwang ◽  
Ji-Young Hwang ◽  
Jin Hee Moon ◽  
Ik Yang ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Diseases ◽  
Overt Hypothyroidism ◽  
Children And Adolescent ◽  
Ultrasound Findings ◽  
The Relationship ◽  
Overt Hyperthyroidism

AbstractTo evaluate the association between thyroid echogenicity and heterogeneity seen on ultrasonography (US) and thyroid function in pediatric and adolescent populations with autoimmune diffuse thyroid diseases (AITD). From 2000 to 2020, we reviewed thyroid ultrasound (US) images and thyroid function statuses in 133 children and adolescent AITD patients. Our review of the images focused on decreased echogenicity and heterogeneity, which were classified into four grades. Among patients with overt hypothyroidism or overt hyperthyroidism, 94.2% (65/69) showed a US grade of 3 or 4. In patients with subclinical hyper/hypothyroidism or euthyroidism, 45.3% (29/64) showed grades 1 or 2. There were no overt hyper/hypothyroidism patients with US grade 1. When we compared US grades according to thyroid status, more severe thyroid dysfunction was significantly associated with higher US grade (p = 0.047). Thyroid stimulating hormone (TSH) level differed significantly according to US grades when we evaluated hyperthyroid (p = 0.035) and hypothyroid (p = 0.027) states independently. 11 patients showed both US grade and thyroid function status changes on follow-up US. In children and adolescent AITD patients, there was an association between decreased echogenicity and heterogeneity on US and thyroid dysfunction.

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