scholarly journals Effects of the additives growth promoters on performance, diarrhea incidence and relative weight of organs of weanling pigs challenged with E.coli K88+

2015 ◽  
Author(s):  
L. B. Costa ◽  
C. Andrade ◽  
S. H. Weber ◽  
V. S. Miyada ◽  
C. M. Nyachoti
Keyword(s):  
Relative Weight ◽  
Growth Promoters ◽  
Weanling Pigs ◽  
Diarrhea Incidence

Board Invited Review: Management and feeding strategies to ameliorate the impact of removing antibiotic growth promoters from diets fed to weanling pigs

2010 ◽  
Vol 90 (4) ◽  
pp. 447-460 ◽  
Author(s):  
D.Y. Kil ◽  
H.H. Stein
Keyword(s):  
Feeding Strategies ◽  
Growth Promoters ◽  
Weanling Pigs ◽  
Liquid Form ◽  
Review Management ◽  
Antibiotic Growth Promoters ◽  
Negative Impacts ◽  
Hind Gut ◽  
Ad Libitum Intake ◽  
The Impact

A review of the literature was conducted with the objective of identifying management and feeding strategies for weanling pigs that are effective in reducing the negative impacts of discontinued use of antibiotic growth promoters (AGP) in diets fed to weanling pigs. If no AGP are used, dietary crude protein concentrations should be reduced to less than 18% in diets fed to pigs during the immediate post-weaning period. Diets should be fed in a liquid form if possible, preferably as fermented liquid feed. Feed intake should be restricted to 75% of ad libitum intake during the initial 2 wk post-weaning to reduce the amount of substrates available to pathogens in the hind gut. The profit from pig production will be maximized if pigs are weaned between 21 and 28 d of age. All-in all-out production should be practiced and pigs should always be weaned into an empty, clean, and disinfected room, preferably at a location separated from the sow farm. Disease pressure and mortality do not necessarily have to increase if no AGP are used, but profits will likely be reduced because costs of preventing diseases in pigs fed diets containing no AGP often are greater than the cost of AGP.

scholarly journals Alternatives to antibiotic growth promoters for weanling pigs

2015 ◽  
Vol 45 (6) ◽  
pp. 1093-1098 ◽  
Author(s):  
Marconi Bonfim de Santana ◽  
Antonio Diego Brandão Melo ◽  
Daniel Ribeiro Cruz ◽  
Cesar Augusto Pospissil Garbossa ◽  
Carla de Andrade ◽  
...  
Keyword(s):  
Sodium Butyrate ◽  
Plant Extracts ◽  
Intestinal Epithelium ◽  
Block Design ◽  
Basal Diet ◽  
Experimental Unit ◽  
Growth Promoters ◽  
Weanling Pigs ◽  
Pig Performance ◽  
Digestive Contents

An experiment was conducted to evaluate the addition of sodium butyrate, plant extracts and nucleotides on weanling pig performance, digestive content pH, organ morphometry, and intestinal epithelial histology. A total of 90 piglets at 21 days of age and an average initial weight of 6.35±0.34kg were used. The piglets were distributed in a randomized complete block design with five treatments, six replicates, and three animals per experimental unit. The treatments consisted of the following: Control: basal diet without antibiotic; Antibiotic: basal diet with 40mg kg-1 colistin sulfate and Additive: 1000, 1500 and 2000mg kg-1 of a combination of sodium butyrate + plant extracts + nucleotides. The experiment lasted 35 days, at which time one animal was slaughtered to assess pH of the digestive contents, morphometry of the organs and histology of the intestinal epithelium. No differences were found (P>0.05) in the performance, pH of the digestive contents, morphometry of the organs or histology of the intestinal epithelium by the analysis of orthogonal polynomials or contrasts. The combination of sodium butyrate, plant extracts and nucleotides not improved the productive characteristics of weanling pigs.

scholarly journals Efficacy of organic acids as an alternative to antibiotic growth promoters in weaned pigs

2018 ◽  
Vol 17 (06) ◽  
pp. 8-14
Author(s):  
Tung M. Che
Keyword(s):  
Organic Acids ◽  
Antibiotic Treatment ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Positive Control ◽  
Negative Control ◽  
Growth Promoters ◽  
Weaned Pigs ◽  
E Coli ◽  
Diarrhea Incidence

The objective of the experiment was to compare effects of dietary supplementation of organic acids (ProHacid Advance, PRO) and antibiotics on growth performance, diarrhea incidence, frequency of antibiotic treatment, and E. coli shedding in weaned pigs. A total of 224 crossbred weaned pigs [(Yorkshire x Landrace) x Duroc; 29 days old)] were allotted to 1 of 4 treatments with 7 replicate pens of 8 pigs each according to sex, litter origin and weight in an RCBD. The 4 dietary treatments included (1) basal diet + 50 mg/kg neomycin and 10 mg/kg enramycin (positive control, PC), (2) basal diet without antibiotics (negative control, NC), (3) As 2 + 0.25% PRO, and (4) As 2 + 0.5% PRO. Over a 4-week study, the results showed that there were no differences in the average daily gain and average daily feed intake of pigs among the 4 treatments (P = 0.328). However, pigs fed the PC diet (1.642) and 0.25% PRO-supplemented diet (1.641) had a lower feed to gain ratio (P < 0.05) than those fed the NC diet (1.808). The diarrhea incidence of pigs fed the 0.25% PRO-supplemented diet (7.36%) was lower (P < 0.01) than that of pigs fed the PC diet (11.61%), NC diet (16.70%), and 0.5% PRO-supplemented diet (10.08%). The frequency of antibiotic treatment of pigs consuming the 0.25% PRO-supplemented diet (4.67%) was lower (P < 0.01) than that of pigs consuming the PC diet (7.33%), NC diet (9.53%) and 0.5% PRO-supplemented diet (7.65%). No differences were found in the number of fecal E. coli among the 4 treatments. In brief, 0.25% PRO added to a nursery pig diet would be considered a potential alternative to the use of antibiotics in feed, but further research on this aspect is needed

scholarly journals Performance and intestinal health of weanling pigs fed with dietary nucleotides

2016 ◽  
Vol 37 (4) ◽  
pp. 2181 ◽  
Author(s):  
Carla De Andrade ◽  
Vivian Vezzoni de Almeida ◽  
Maicon Sbardella ◽  
Danilo Do Prado Perina ◽  
Fabiane De Lima Silva ◽  
...  
Keyword(s):  
Body Weight ◽  
Average Daily Gain ◽  
Relative Weight ◽  
Basal Diet ◽  
Intestinal Histology ◽  
Weanling Pigs ◽  
Salmonella Spp ◽  
Final Body Weight ◽  
Dietary Nucleotides ◽  
Daily Gain

Previous studies reported benefits to growth performance, intestinal histology and reduced diarrhea for pigs supplemented with nucleotide additive as a replacement to antimicrobial growth promoters. The purpose of this study was to evaluate the effects of nucleotide levels on performance, occurrence of diarrhea, relative weight of organs, intestinal histology, and intestinal microbiota of weanling pigs. One hundred and sixty 21-d weaned pigs (6.43 ± 0.71 kg BW) were used in a randomized complete block design experiment with five treatments, eight replications per treatment and four animals per pen (experimental unit). The treatments were basal diet with 120 ppm of chloro-hydroxyquinoline (antimicrobial), and basal diet with 0 (control), 100, 150, or 200 ppm of nucleotides. The average daily gain (ADG), average daily feed intake (ADFI), gain to feed ratio (G:F), and occurrence of diarrhea were calculated from day 1 to 14, day 14 to 34, and day 1 to 34 of the experiment. A day after the end of the experiment, one animal from each pen was slaughtered to evaluate the relative weight of organs, intestinal histology, and intestinal microbiota. From day 1-14 and day 14-34 of the experiment, performance was not affected by the treatments. For the total experimental period (day 1-34), increasing the dietary concentrations of nucleotides linearly improved the final body weight and average daily gain. Salmonella spp. was detected only in the control treatment, without affecting the other microorganisms. Pigs fed with antibiotic had a lower occurrence of diarrhea from day 1-14 compared to pigs fed with nucleotide treatments. Although increasing the occurrence of diarrhea in the first 14 days, dietary nucleotides added up to 200 ppm, improve the final body weight and average daily gain at 34 days post weaning. Nucleotides and antimicrobial not shown beneficial effects on organ weights, and intestinal histology of nursery pig, however, are able to decrease the population of Salmonella spp. at small intestine.

scholarly journals Herbal extracts and symbiotic mixture replacing antibiotics in piglets at the initial phase

2011 ◽  
Vol 40 (5) ◽  
pp. 1045-1051 ◽  
Author(s):  
Márcio Gilberto Zangeronimo ◽  
Vinícius de Souza Cantarelli ◽  
Elias Tadeu Fialho ◽  
Níkolas de Oliveira Amaral ◽  
Hebert Silveira ◽  
...  
Keyword(s):  
Initial Phase ◽  
Basal Diet ◽  
Experimental Unit ◽  
Average Weight ◽  
Feed Conversion ◽  
Initial Weight ◽  
Growth Promoters ◽  
Herbal Mixture ◽  
Vegetable Extract ◽  
Diarrhea Incidence

The objective of this work was to evaluate the use of vegetable extract based addictives associated or not to symbiotics as an alternative for antibiotic as growth promoters for piglets at initial phase. It was used 125 pigs of commercial genetic line with initial weight of 7.4 ± 1.1 kg, weaned at 20 days of age, during 50 days. The experimental design used was randomized blocks (initial weight), with five treatments and five replicates with five animals per experimental unit. The experimental diets were a basal diet, without additive, and other four diets, one diet containing antibiotic (colistin + zinc oxide); diet with 0.3% of a symbiotic mixture; diet with 0.3% of a symbiotic mixture plus 0.05% of herbal mix (plant extracts and microencapsulated essential oils); and another diet with 0.3% of symbiotic mixture plus 0.1% of herbal mixture. It was observed that the use of the symbiotic mixture associated to 0.05% of herbal mixture showed positive results, similar to the ones obtained with diets containing antibiotics for the final weight, average weight gain, average daily feed intake and pH of stomach and diarrhea incidence. The use of symbiotics promoted smaller vilous:depth crypt ratio, except when associated to 0.1% of herbal mixture, which was similar to the diet without addictives. There was no differences in the feed conversion, coliform and lactobacillus count in the jejune and in the cecum and in the pH of cecum. The use of herbal mixture associated to symbiotic is a viable alternative for replacing the use of antibiotics as growth promoters for piglets in the initial phase. However, the concentration of the herbal mixture is an important factor to be considered.

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