scholarly journals Randomized Clinical Trial Between Fluoxetine and Dapoxetine for Premature Ejaculation and Its Effect on Marital Relationship

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Che Man M ◽  
Mohd Zin F ◽  
Che Alhadi S ◽  
Yaacob NM ◽  
Ismail SB

INTRODUCTION: Premature ejaculation(PE) decreases sexual pleasure and quality of life, and both Fluoxetine and Dapoxetine were used in PE therapy. Dapoxetine is the first SSRI with a short half-life and fewer side effects, primarily designed for PE therapy. The aim is to evaluate and compare the effects of Fluoxetine and Dapoxetine on PE symptoms and marital satisfaction. MATERIALS AND METHODS: 44 participants aged between 18 and 64 with a PEDT score of ≥9 from Hospital USM's Primary-Care-Clinic, Kelantan Malaysia were selected and randomized into two groups: Fluoxetine(FG) and Dapoxetine Group(DG), and administered for 8 weeks with either regular Fluoxetine(20mg) or Dapoxetine (30mg) on-demand at least once a week. Premature Ejaculation Diagnostics Tool(PEDT) score was used to assess PE symptoms and Dyadic Satisfaction-Dyadic Adjustment Scale (DS-DAS) used to evaluate marital satisfaction at baseline and the 8th week. RESULT: 22 and 21 participants in FG and DG completed the study. For both groups, PEDT scores decreased substantially [from 11.41 to 5.45(P< 0.001) among FG, from 13.43 to 3.10(P<0.001) among DG]. After adjustment of the baseline PEDT score, PEDT scores in DG(6.03 vs 2.49, P><0.001) were lower at the 8th week. All groups showed significantly improved DS-DAS scores [from 34.50 to 40.68(P><0.001) in FG, from 36.57 to 44.33(P><0.001) in DG]. No marked difference in DS-DAS was scored after adjustment of the baseline DS-DAS score(41.13 vs 43.86, P=0.055) at the end of the assessment. CONCLUSION: Treatment of PE with either Fluoxetine or Dapoxetine decreases PE symptoms and increases marital satisfaction. ><0.001) among DG]. After adjustment of the baseline PEDT score, PEDT scores in DG (6.03 vs 2.49, P< 0.001) were lower at the 8th week. All groups showed significantly improved DS-DAS scores [from 34.50 to 40.68(P< 0.001) in FG, from 36.57 to 44.33(P< 0.001) in DG]. No marked difference in DS-DAS was scored after adjustment of the baseline DS-DAS score (41.13 vs 43.86, P=0.055) at the end of the assessment. CONCLUSION: Treatment of PE with either Fluoxetine or Dapoxetine decreases PE symptoms and increases marital satisfaction.

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Mohammad Che Man ◽  
Faridah Mohd Zain ◽  
Najib Majdi Yaacob ◽  
Shahidah Che Alhadi ◽  
Shaiful Bahri Ismail

Introduction:  Premature ejaculation (PE) reduces sexual satisfaction and quality of life. Both SSRI Fluoxetine and Dapoxetine have been used in the treatment of PE. Fluoxetine is used as off-label treatment meanwhile Dapoxetine is the first SSRI specifically designed for PE with short half-life and few side effects. Objectives: To compare the PE symptoms and marital satisfaction score between Fluoxetine and Dapoxetine groups. Materials and method: In this clinical trial, 44 participants aged between 18 and 64 with PEDT score of ≥9 from the Primary Care clinic of Hospital USM, Kelantan were recruited and randomized into two groups; Fluoxetine Group(FG) and Dapoxetine Group(DG). They were prescribed with either daily oral Fluoxetine 20mg or Dapoxetine 30mg on demand twice weekly for 8 weeks. PE symptoms were measured using the Premature Ejaculation Diagnostics Tool(PEDT) score and marital satisfaction score were measured using the Dyadic Satisfaction-Dyadic Adjustment Scale(DS-DAS) score. Measurements were made at baseline and at the 8thweek(post intervention). Results: In FG and DG, 22 and 21 participants completed the study, respectively. PEDT scores reduced significantly within both groups[from 11.41 to 5.45(P<0.001) within FG and from 13.43 to 3.10(P<0.001) within the DG]. At the 8thweek follow-up, PEDT scores was observed to be were lower in DG(6.03 vs. 2.49,P<0.001) after adjustment of the baseline PEDT score. Significantly increased DS-DAS scores were observed in both groups [from 34.50 to 40.68(P<0.001) within FG and from 36.57 to 44.33,(P<0.001) within DG] with no significant difference in DS-DAS scores at the end of study(41.13 vs. 43.86,P=0.055) after adjustment of the baseline DS-DAS score. Conclusion: Reduction in PE symptoms was observed for both groups. At 8 weeks, PE symptoms among participants on Dapoxetine were significantly lower compared to the participants on Fluoxetine at 8 weeks. Treatment of PE with either Fluoxetine or Dapoxetine reduces symptoms of PE and improves marital satisfaction.


1990 ◽  
Vol 16 (2) ◽  
pp. 108-112 ◽  
Author(s):  
Barbara A. Pieper ◽  
Wendla Kushion ◽  
Susan Gaida

Twenty married couples with one partner diagnosed as having diabetes at age 40 or older within the past 5 years participated in this study. Participants completed the diabetes or family version of Beliefs About Diabetes (BAD) and the Dyadic Adjustment Scale (DAS). Results showed that perceived barriers to diet and to medication by the person with diabetes were associated with higher marital satisfaction and quality of marriage. In contrast, for the nondiabetic spouse, the perceived benefits of diet were negatively associated with the ability to work with the diabetic spouse. Additional research is needed to better understand the effect of diabetes on the marital relationship.


2005 ◽  
Vol 33 (4) ◽  
pp. 313-328 ◽  
Author(s):  
Zeynep Hamamci

This study investigated the association between dysfunctional relationship beliefs and marital relationships of Turkish nonclinical married individuals. The Interpersonal Cognitive Distortions Scale (Hamamci & Büyüközturk, 2004), Dyadic Adjustment Scale (Spanier, 1976), and Marriage Life Scale (Tezer, 1986), which measure marital satisfaction, were administered to the sample of 190 married females and males. Analysis revealed that married individuals with low dyadic adjustment endorsed significantly more dysfunctional relationship beliefs than did those with high dyadic adjustment. It was found that dysfunctional relationship beliefs, including especially beliefs concerning being very close to others in their relationships causing negative consequences, have negative and moderate level correlation with the marital adjustment of males, and negative and very low level correlations were found between marital satisfaction and dysfunctional relationships beliefs. But mindreading beliefs were positively associated with the marital satisfaction of females. Although there were no significant age or gender differences in dysfunctional relationship beliefs, significant differences were observed in dysfunctional relationship beliefs in terms of the education level of married individuals.


1980 ◽  
Vol 47 (2) ◽  
pp. 555-558
Author(s):  
Paul Grayson

Three hypotheses about the relationship between personality and marital or dyadic satisfaction were investigated. Married or cohabiting couples filled out the Adjective Check List, Lowman's Inventory of Family Feelings, and Spanier's Dyadic Adjustment Scale. Correlation coefficients between personality scales and ratings of satisfaction and of differences between man and woman on personality scales suggested that satisfaction is related to sex differentiation and similarity but not to individual psychopathology.


1997 ◽  
Vol 27 (3) ◽  
pp. 171-174 ◽  
Author(s):  
T. Brian Pretorius

Dyadic quality is described as the quality of the relationship between two partners which is dependent on the level of dyadic cohesion, dyadic consensus, dyadic satisfaction and dyadic adjustment, as well as the way in which the couple deals with conflict. These aspects were measured using the Conflict Tactics Scale and the Dyadic Adjustment Scale. Social support was measured using the Inventory of Socially Supportive Behaviors (ISSB) and the Social Support Questionnaire (SSQ). The purpose of the study was to determine whether there is any relationship between dyadic quality and dimensions of social support. Respondents were 163 undergraduate students at the University of Western Cape, South Africa. Multiple regression analyses indicated that a number of the indices of dyadic quality were significant predictors of the dimensions of social support. The result suggests that the quality of dyadic relationships impacts on the perceived availability and satisfaction with support. Research aimed at exploring and understanding the health-sustaining and stress-reducing functions of social support needs to focus on the potential negative impact of dyadic conflict and poor dyadic adjustment on the experience of social support.


1984 ◽  
Vol 54 (2) ◽  
pp. 629-630 ◽  
Author(s):  
Kelly J. Grover ◽  
Lois A. Paff-Bergen ◽  
Candyce S. Russell ◽  
Walter R. Schumm

The Kansas Marital Satisfaction Scale was administered by survey to 51 wives between the ages of 32 and 71 yr. Further support for the internal consistency reliability of the scale (α = 0.92) was obtained, and patterns of differences between the item means paralleled previous research. Evidence was found for the concurrent validity of the scale, which correlated significantly with six of seven items from the satisfaction subscale of Spanier's Dyadic Adjustment Scale.


2006 ◽  
Vol 65 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Jérôme Rossier ◽  
Christine Rigozzi ◽  
Linda Charvoz ◽  
Guy Bodenmann

This study examines the psychometric properties of the French-version of the Partnership Questionnaire (PFB) and compares this questionnaire with the Dyadic Adjustment Scale (DAS). 225 couples, married or living together for at least 3 years, participated in this research and each partner responded individually to the PFB or to both scales. The results indicate that the structure of the PFB replicates the theoretical three-factor structure for both women and men. Moreover, the cross-language replicability of the structure was high. The correlation between the DAS and the PFB was also high (r = .79) and the three canonical correlation variates explained 58% or more of the variance of both scales. The PFB is sensitive to couple characteristics and the agreement within couples is high. The French-version of the PFB has good psychometric properties and seems well suited for measuring marital satisfaction for clinical and research purposes.


2012 ◽  
Vol 2012 ◽  
pp. 1-8
Author(s):  
Kim Kristiansen ◽  
Pernille Lyngholm-Kjaerby ◽  
Claus Moe

Background. Coexistence of pain and depression has significant impact on the patient’s quality of life and treatment outcome. DoloTest is a pain and HRQoL assessment tool developed to provide shared understanding between the clinician and the patient of the condition by a visual profile. Aim. To find the sensitivity and specificity of DoloTest as a screening tool for depression for patients in primary care. Methods. All patients coming to a primary care clinic were asked to fill in a DoloTest and a Major Depression Inventory. Results. 715 (68.5%) of 1044 patients entered the study. 34.4% came due to pain. 16.1% met depression criteria, and 26.8% of patients coming due to pain met criteria for depression. 65.6% of the men and 54.2% of the women meeting the criteria for depression came due to pain. Depressed patients had statistically significant higher scores on all DoloTest domains. Selecting the cutoff value for the domain “low spirits” to be “65” (0–100) for depression gave a sensitivity of 78% (70–85%) and a specificity of 95% (93–96%) for meeting depression criteria. Conclusion. DoloTest can with a high sensitivity and specificity identify persons meeting criteria for depression and is an easy-to-use screening tool to identify patients with the coexistence of pain and depression.


2006 ◽  
Vol 14 (3) ◽  
pp. 181-189 ◽  
Author(s):  
JoAnne M. Youngblut ◽  
Dorothy Brooten ◽  
Victoria Menzies

Although Hispanic Americans are one of the fastest growing ethnic populations in the United States, use and psychometric testing of Spanish versions of two instruments commonly used to measure quality of the couple’s relationship and family functioning, the Dyadic Adjustment Scale (DAS) and the FACES II, have not been reported. The purpose of this study was to test the psychometric properties of the newly translated Spanish version of these two instruments. In this bilingual sample of 78 adults, internal consistencies were acceptable (.72 to .77 for the FACES II; .67 to .93 for the DAS) and test-retest correlations were high (.80 to .88 FACES II; .79 to .87 DAS). Correlations between the Spanish and English versions were also high (.87 to .94 FACES II; .91 to .99 DAS). Psychometric findings support the reliability and validity of the Spanish versions of these newly translated measures.


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