Effects of exchanging lactose for fat in milk replacer on ad libitum feed intake and growth performance in dairy calves

Abstract Reducing dietary crude protein (CP) with synthetic amino acids (AA) supplementation is beneficial for sustainable swine industry. However some discrepancies regarding the consequences on growth performance are observed. Therefore, this trial aimed to assess the effect of dietary CP level on growth performance of pigs from 35 to 113 kg BW. Growth performance of 63 pigs fed ad libitum and allocated to three groups (HH, MM and LL) was compared. Each group received one level of CP (‘H’ for High, ‘M’ for Medium and ‘L’ for Low) during growing (d0–d35) and finishing (d35–slaugther day) periods: 15.1%, 16.2%, 17.2% and 13.0%, 14.0%, 15.1% respectively. Diets were mostly based on wheat, corn and soybean meal. Within each feeding phase, diets were formulated to be similar in apparent total tract digestible phosphorus, net energy and standardized ileal digestible (SID) essential AA, the SID Lys levels being 0.95% and 0.78% during the growing and finishing period respectively. Data were analyzed using a linear model (R, 3.1.2) with individual as the experimental unit as feed intake, body weight and carcass grading were individually recorded. From d0 to d14 and from d35 to d63, average daily gain (ADG) and Growth:Feed ratio (G:F) were significantly reduced as the CP level decreased (P < 0.05) while average daily feed intake (ADFI) remained unaffected by the dietary treatments. From d14 to d35 and in late finishing period (d63-slaugther day), growth performance was not significantly affected by the dietary CP level. Over the 82-d of the experiment, G:F was significantly higher for ‘HH’ pigs (P < 0.01). Overall, ADG tended to be reduced as CP levels decreased (P = 0.10). There was no difference among treatments for parameters concerning carcass grading (lean meat percentage and meat yield). In conclusion, reducing CP levels while maintaining essential AA levels impaired growth performances of pigs.

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Impact of porcine reproductive and respiratory syndrome virus on muscle metabolism of growing pigs1

Journal of Animal Science ◽

10.1093/jas/skz168 ◽

2019 ◽

Vol 97 (8) ◽

pp. 3213-3227 ◽

Cited By ~ 4

Author(s):

Emma T Helm ◽

Shelby M Curry ◽

Carson M De Mille ◽

Wesley P Schweer ◽

Eric R Burrough ◽

...

Keyword(s):

Skeletal Muscle ◽

Protein Synthesis ◽

Growth Performance ◽

Feed Intake ◽

Feed Efficiency ◽

Growing Pigs ◽

Nutrient Restriction ◽

Viral Challenge ◽

Prrs Virus ◽

Ad Libitum

Abstract Porcine reproductive and respiratory syndrome (PRRS) virus is one of the most economically significant pig pathogens worldwide. However, the metabolic explanation for reductions in tissue accretion observed in growing pigs remains poorly defined. Additionally, PRRS virus challenge is often accompanied by reduced feed intake, making it difficult to discern which effects are virus vs. feed intake driven. To account for this, a pair-fed model was employed to examine the effects of PRRS challenge and nutrient restriction on skeletal muscle and liver metabolism. Forty-eight pigs were randomly selected (13.1 ± 1.97 kg BW) and allotted to 1 of 3 treatments (n = 16 pigs/treatment): 1) PRRS naïve, ad libitum fed (Ad), 2) PRRS-inoculated, ad libitum fed (PRRS+), and 3) PRRS naïve, pair-fed to the PRRS-inoculated pigs’ daily feed intake (PF). At days postinoculation (dpi) 10 and 17, 8 pigs per treatment were euthanized and tissues collected. Tissues were assayed for markers of proteolysis (LM only), protein synthesis (LM only), oxidative stress (LM only), gluconeogenesis (liver), and glycogen concentrations (LM and liver). Growth performance, feed intake, and feed efficiency were all reduced in both PRRS+ and PF pigs compared with Ad pigs (P < 0.001). Furthermore, growth performance and feed efficiency were additionally reduced in PRRS+ pigs compared with PF pigs (P < 0.05). Activity of most markers of LM proteolysis (μ-calpain, 20S proteasome, and caspase 3/7) was not increased (P > 0.10) in PRRS+ pigs compared with Ad pigs, although activity of m-calpain was increased in PRRS+ pigs compared with Ad pigs (P = 0.025) at dpi 17. Muscle reactive oxygen species production was not increased (P > 0.10) in PRRS+ pigs compared with Ad pigs. However, phosphorylation of protein synthesis markers was decreased in PRRS+ pigs compared with both Ad (P < 0.05) and PF (P < 0.05) pigs. Liver gluconeogenesis was not increased as a result of PRRS; however, liver glycogen was decreased (P < 0.01) in PRRS+ pigs compared with Ad and PF pigs at both time points. Taken together, this work demonstrates the differential impact a viral challenge and nutrient restriction have on metabolism of growing pigs. Although markers of skeletal muscle proteolysis showed limited evidence of increase, markers of skeletal muscle synthesis were reduced during PRRS viral challenge. Furthermore, liver glycogenolysis seems to provide PRRS+ pigs with glucose needed to fuel the immune response during viral challenge.

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Effect of residual feed intake phenotype–nutritional treatment interaction on the growth performance, plasma metabolic variables and somatotropic axis gene expression of growing ewes

Animal Production Science ◽

10.1071/an14700 ◽

2016 ◽

Vol 56 (10) ◽

pp. 1593 ◽

Cited By ~ 1

Author(s):

H. T. Nie ◽

Z. Y. Wang ◽

S. Lan ◽

H. Zhang ◽

Y. J. Wan ◽

...

Keyword(s):

Gene Expression ◽

Growth Hormone ◽

Growth Performance ◽

Feed Intake ◽

Mrna Abundance ◽

Feed Restriction ◽

Somatotropic Axis ◽

Nutritional Treatment ◽

Treatment Interaction ◽

Ad Libitum

This study aimed to evaluate the effect of residual feed intake (RFI) phenotype and nutritional treatment interaction on the growth performance, plasma variables and gene expression levels within the somatotropic axis. Growing ewes [n = 52, initial bodyweight (BW) = 17.5 ± 0.5 kg, 2 months of age] were offered ad libitum access to diets for 63 days and ranked based on RFI phenotype. Thirty ewes with the highest and lowest RFI values were selected and randomly assigned to three nutritional treatments based on dry matter intake (DMI), which are ad libitum (AL), low restriction (LR) and high restriction (HR) groups, respectively. Each nutritional treatment group included ewes with high (n = 5) and low RFI (n = 5) values. During nutritional treatment (from Day 64 to Day 138), plasma samples were obtained to measure metabolite and hormone concentrations. Tissues of the hypothalamus, pituitary, liver, and Longissimus dorsi muscle (LM) were harvested at the end of the experiment (Day 138) to measure the gene expression level within the somatotropic axis. Muscle growth hormone receptor mRNA abundance of low RFI ewes tended to be greater (P = 0.09) under AL feeding, but this difference was abolished by underfeeding (P > 0.10). Low RFI ewes under HR treatment showed slightly greater growth performance, which was accompanied with lower pituitary somatostain receptor 2 mRNA abundance (P < 0.05), plasma non-esterified fatty acid concentration (P < 0.05), and greater concentration of triglyceride (P < 0.05), compared with ewes classified as high RFI group. Our results suggested that ewes categorised as low RFI showed higher resistance to the condition of high feed restriction, which might be attributed to less intensity of fat mobilisation under negative energy balance. The mechanism underlying resistance to such feed restriction was presumably through action of somatostain receptor 2 and was potentially mediated by inhibitory effects of somatostatin on growth hormone release but not basal growth hormone secretion.

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Effects of a blend of essential oils in milk replacer on performance, rumen fermentation, blood parameters, and health scores of dairy heifers

PLoS ONE ◽

10.1371/journal.pone.0231068 ◽

2021 ◽

Vol 16 (3) ◽

pp. e0231068

Author(s):

Joana Palhares Campolina ◽

Sandra Gesteira Coelho ◽

Anna Luiza Belli ◽

Fernanda Samarini Machado ◽

Luiz Gustavo R. Pereira ◽

...

Keyword(s):

Essential Oils ◽

Feed Intake ◽

Block Design ◽

Rumen Fermentation ◽

Milk Replacer ◽

Genetic Composition ◽

Dairy Heifers ◽

Body Development ◽

Ad Libitum ◽

Carry Over

The aim of this study was to evaluate how the inclusion of a blend of essential oils in milk replacer (MR) affects different outcomes of dairy heifers. The outcomes evaluated: feed intake, performance, body development, blood cells and metabolites, insulin-like growth factor-1 (IGF-1), rumen fermentation, fecal scores, and respiratory scores. All outcomes were evaluated during pre-weaning (4–60 d of age), and carry-over effects during post-weaning (61–90 d of age) periods. The experimental units utilized were 29 newborn Holstein × Gyr crossbred dairy heifers, with genetic composition of 5/8 or more Holstein and 3/8 or less Gyr and body weight (BW) at birth of 32.2 ± 5.2 kg. Experimental units were assigned to either a control (CON, n = 15) or a blend of essential oil supplementation (BEO, n = 14) treatment, maintaining a balance of genetic composition. The BEO was supplemented in the MR with 1 g/d/calf of a blend of essential oils (Apex Calf, Adisseo, China) composed by plant extracts derived from anise, cinnamon, garlic, rosemary, and thyme. During the pre-weaning phase, all heifers were fed 5 L of MR/d reconstituted to 15% (dry matter basis), divided into two equal meals. Water and starter were provided ad libitum. During the post-weaning, animals received a maximum of 3 kg of starter/d, and ad libitum corn silage, divided into two meals. Feed intake, fecal and respiratory scores were evaluated daily. The BW was measured every three days, while body development was recorded weekly. Blood samples were collected on 0, 30, and 60 d of age for total blood cell count, weekly and on the weaning day to determinate ß-hydroxybutyrate, urea and glucose, and biweekly for IGF-1. Ruminal parameters (pH, volatile fatty acids, ammonia-N, and acetate:propionate proportion—C2:C3) were measured on days 14, 28, 42, 60, 74 and 90. A randomized complete block design with an interaction between treatment and week was the experimental method of choice to test the hypothesis of the BEO’s effect on all outcomes. An ANOVA procedure was used for continuous outcomes, and a non-parametric test was used for the ordered categorical outcomes, both adopting a CI = 95%. Results indicated that there was not enough evidence to accept the alternative hypothesis of the effect of BEO in MR on feed intake, performance, body development, and blood metabolites during both pre-weaning and post-weaning periods. However, results indicated that the inclusion of BEO in MR significantly affects the proportion of C2:C3 during pre- and post-weaning (P = 0.05). Similarly, the effect was significant for basophil (P ≤ 0.001), and platelet (P = 0.04) counts pre-weaning. The interaction between week and treatment was also significant for lymphocytes (P ≤ 0.001), revealing a cumulative effect. Lastly, fecal scores were also significant (P = 0.04) during pre-weaning, with lower values for BEO. The BEO contributed to ruminal manipulation in pre-weaning and carry-over effects in post-weaning, immunity improvement, and decreased morbidity of neonatal diarrhea in the pre-weaning phase.

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Growth performance and nutrient digestibility of broiler finishers fed processed Mucuna pruriens seed meal

Nigerian Journal of Animal Production ◽

10.51791/njap.v48i3.2956 ◽

2021 ◽

Vol 48 (3) ◽

pp. 86-92

Author(s):

C. O. Akure ◽

A. A. Sekoni ◽

F. O. Abeke ◽

P. A. Vantsawa ◽

B. Babasanya ◽

...

Keyword(s):

Weight Gain ◽

Growth Performance ◽

Feed Intake ◽

Control Diet ◽

Nutrient Digestibility ◽

Seed Meal ◽

Mucuna Pruriens ◽

Feed Cost ◽

Final Weight ◽

Ad Libitum

This study was carried out to evaluate the effect of 45 minutes Boiled Mucuna Seed Meal (BMSM) on the growth performance and nutrient digestibility of broiler finisher chicks. In a four-week feeding trial, three hundred and fifteen (315),4-week old broiler chicks were randomly allocated to five experimental treatment diets in a completely randomized design (CRD). Each treatment was replicated thrice having twenty-one (21) birds per pen. Boiled Mucuna seed meal was prepared and fed in graded levels of 0.0% (control diet), 10.0%, 20.0%, 30.0%, and 40.0%BMSM. Feed and water were given to the birds ad libitum. The parameters measured and calculated include final weight, weight gain, feed intake, feed to gain ratio and feed cost per kilogram gain. Digestibility of dry matter, crude protein; crude fibre, ash, nitrogen free extract and ether extract were also determined. The data collected were subjected to analysis of variance (ANOVA). The results showed that dietary levels of inclusion of BMSM had significant (P<0.05) effect on these parameters. The final weight, the weight gain and feed intake of the birds fed 0.0%, 10.0% and 20.0%BMSM were statistically (P>0.05) similar and significantly (P<0.05) higher than those of other treatments. Cost of feed per birds and feed cost per kilogram gain were lower for all BMSB diets.Digestibility of nutrients was better for the birds fed the control,10.0 and 20.0%BMSM based diets. It was concluded that inclusion of BMSM in the diets of broiler finisher chicks up to20% has no deleterious effect on growth performance and nutrient digestibility of the birds. Cette étude a été réalisée pour évaluer l'effet de 45 minutes de farine de graines de Mucuna (le 'BMSM') bouillie sur la performance de croissance et la digestibilité des éléments nutritifs des poussins finisseurs de poulet à griller. Dans un teste d'alimentation de quatre semaines, trois cent quinze (315), poussins de poulet de griller de 4 semaines ont été aléatoirement attribués à cinq régimes expérimentaux de traitement dans une conception complètement randomisée (le 'CRD'). Chaque traitement a été reproduit trois fois avec vingt et un (21) oiseaux par enclos. Le repas bouilli de graine de Mucuna a été préparé et alimenté dans les niveaux classés de 0.0% (régime de contrôle), 10.0%, 20.0%, 30.0%, et 40.0%BMSM. L'alimentation et l'eau ont été données aux oiseaux ad libitum. Les paramètres mesurés et calculés comprennent le poids final, le gain de poids, la prise d'aliments pour animaux, le rapport alimentation/gain et le coût des aliments pour animaux par gain kilogramme. La digestibilité de la matière sèche, protéines brutes; des fibres brutes, des cendres, de l'extrait sans azote et de l'extrait d'éther ont également été déterminés. Les données recueillies ont fait l'objet d'une analyse de la variance (ANOVA). Les résultats ont montré que les niveaux diététiques d'inclusion de 'BMSM' ont eu un effet significatif (P<0.05) sur ces paramètres. Le poids final, le gain de poids et la prise d'alimentation des oiseaux nourris 0.0%, 10.0% et 20.0%BMSM étaient statistiquement (P>0.05) semblables et significativement (P<0.05) plus élevés que ceux des autres traitements. Le coût de l'alimentation animale par oiseau et le coût de l'alimentation par kilogramme étaient inférieurs pour tous les régimes BMSB. La digestibilité des éléments nutritifs était meilleure pour les oiseaux alimentés le contrôle,10.0 et 20.0% BMSM régimes à base. Il a été conclu que l'inclusion du BMSM dans l'alimentation des poussins finisseurs de poulet de gril jusqu'à 20 % n'a aucun effet délétère sur la performance de croissance et la digestibilité des oiseaux en matière d'éléments nutritifs.

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Effects of a blend of essential oils in milk replacer on performance, rumen fermentation, blood parameters and health scores of dairy heifers

10.1101/2020.03.17.995209 ◽

2020 ◽

Author(s):

Joana P. Campolina ◽

Sandra G. Coelho ◽

Anna Luiza Belli ◽

Fernanda S. Machado ◽

Luiz G. R. Pereira ◽

...

Keyword(s):

Essential Oils ◽

Feed Intake ◽

Block Design ◽

Rumen Fermentation ◽

Milk Replacer ◽

Control Group ◽

Dairy Heifers ◽

Body Development ◽

Long Term Treatment ◽

Ad Libitum

AbstractThe objective of this study was to evaluate how the inclusion of a blend of essential oils in milk replacer (MR) affects different outcomes of dairy heifers. The outcomes evaluated: feed intake, performance, body development, blood cells and metabolites, insulin-like growth factor-1 (IGF-1), rumen fermentation, fecal scores and respiratory scores. All outcomes were evaluated during pre-weaning (4 – 60 d of age), and carryover effects on post-weaning (61 – 90 d of age) periods. The experimental units utilized were 29 newborn Holstein × Gyr crossbred dairy heifers, with genetic composition of 5/8 or more Holstein and 3/8 or less Gyr and body weight (BW) at birth of 32.2 ± 5.2 kg. Experimental units were randomly assigned to either a control group (CON, n = 15) or a treatment group, consisting of supplementation of a blend of essential oils (BEO, n = 14) with1 g/d/calf (Apex Calf, Adisseo, China). During the pre-weaning phase, all heifers were fed 5 L of MR/d reconstituted at 15% (dry matter basis), divided into two equal meals. Water and starter were provided ad libitum. During the post-weaning, animals received a maximum 3 kg of starter/d, and ad libitum corn silage, divided into two meals. The outcomes feed intake, fecal and respiratory scores were evaluated daily. BW was measured every three days, while body development was recorded weekly. Blood samples were collected on 0, 30 and 60 d of age for total blood cell count, weekly to determinate ß-hydroxybutyrate, urea and glucose, and biweekly for IGF-1. Ruminal parameters (pH, volatile fatty acids, ammonia-N and acetate:proprionate proportion - C2:C3) were measured each 14 days. A randomized complete block design with an interaction between treatment and week was the experimental method of choice to test the hypothesis of effect of BEO on all outcomes. An ANOVA procedure was used for continuous outcomes and a non-parametric test was used for the ordered categorical outcomes both adopting a C.I. = 95%. Results indicated that there was not enough evidence to accept the alternative hypothesis of effect of BEO in MR on: feed intake, performance, body development and blood metabolites during both pre-weaning and post-weaning periods. However, results indicated that the inclusion of BEO in MR significantly affects the proportion of C2:C3 during pre and post-weaning (P ≤ 0.05). Similarly, the effect is significant for basophil (P ≤ 0.001) and platelet (P ≤ 0.05) counts in pre-weaning. The interaction between week and treatment was also significant for lymphocytes (P ≤ 0.001), revealing a long-term treatment immunological effect. Lastly, the effect on fecal scores was also significant (P ≤ 0.05) during pre-weaning, with lower values for BEO. BEO contributed for ruminal manipulation on pre-weaning and carry over effect on post-weaning; immunity improvement and a decrease morbidity of neonatal diarrhea in pre-weaning phase.

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Intake, nutrient digestibility, and growth performance of Holstein dairy calves consuming a milk replacer at moderate or high feeding rates

Journal of Dairy Science ◽

10.3168/jds.2019-16282 ◽

2019 ◽

Vol 102 (9) ◽

pp. 7917-7926 ◽

Cited By ~ 3

Author(s):

W. Hu ◽

T.M. Hill ◽

T.S. Dennis ◽

F.X. Suarez-Mena ◽

J.D. Quigley ◽

...

Keyword(s):

Growth Performance ◽

Nutrient Digestibility ◽

Dairy Calves ◽

Milk Replacer ◽

Feeding Rates

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The feeding value of different classes of wheat for grower finisher pigs

Australian Journal of Experimental Agriculture ◽

10.1071/ea9760668 ◽

1976 ◽

Vol 16 (82) ◽

pp. 668 ◽

Cited By ~ 6

Author(s):

RH King

Keyword(s):

Growth Performance ◽

Feed Intake ◽

General Purpose ◽

Lower Growth ◽

White Wheat ◽

Weight Range ◽

Australian Standard ◽

Feeding Value ◽

Ad Libitum

A factorial experiment involving two levels of feeding (restricted and ad libitum) and four classes of wheat, these being Australian standard white wheat (ASW), feed wheat damaged by rust (FR), general purpose wheat damaged by weather (GPW) and general purpose wheat damaged by rust (GPR), was carried out to study the effects of different classes of wheats on the growth performance and carcase quality of pigs between 23 and 70 kg liveweight. The digestible energy (DE) contents (+SD) of the wheats, on an air basis were 14.8 (+0.20), 14.8 (+0.20), 14.9 (+0.22) and 14.3 (+0.12) MJ kg-1 for ASW, FR, GPW and GPR, respectively. Wheat class did not affect feed intake of pigs or cause variation in carcase quality. However, pigs fed diets containing GPR or FR wheats did not perform as well as pigs fed diets based on GPW or ASW wheat. This lower growth performance was due to the lower DE content of GPR wheat and the reduced digestibility of protein in both GBR and FR wheats. Pigs fed ad libitum grew faster, had fatter carcases and over the weight range 45 to 70 kg required more feed per unit liveweight gain than pigs fed in restricted amounts.

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