scholarly journals RESULTS OF X-RAY AND DENSITOMETRIC INVESTIGATION IN PATIENTS WITH DESTRUCTIVE FORMS OF APICAL PERIODONTITIS IN EARLY FOLLOW UP PERIOD

2021 ◽  
Vol 21 (2) ◽  
pp. 117-122
Author(s):  
Yu. Yu. Lysokon ◽  
M.O. Iskiv ◽  
M.A. Luchinskyi
Keyword(s):  
Bone Tissue ◽  
Tissue Repair ◽  
Platelet Rich Plasma ◽  
Bone Destruction ◽  
Group Iv ◽  
Apical Periodontitis ◽  
Group Iii ◽  
Osteoplastic Material ◽  
Half Axis

This article presents a comparative analysis of the effectiveness of various treatment approaches, including bone mixture “mp3, Osteobiol, and platelet-enriched plasma, in the therapy of destructive forms of apical periodontitis in the early follow-up. The aim of this work is to investigate the dynamic changes in radiological and densitometric parameters depending on the treatment methods for patients with destructive forms of apical periodontitis in the early follow up period. The study involved 185 patients with destructive forms of apical periodontitis, who were examined and receive the treatment. The subjects were divided into 4 groups. Measurements of the size of the lesion in the bone tissue (for lesions of round shape) were performed by the formula: S = πr2. The area of lesions of elliptical shape was measured by the formula S = π ab, where π = 3.14; r = the radius of the circle; a = the value of the major half-axis of the ellipse; b = the length of the small half-axis of the ellipse. After 3 months of the follow up, the patients of group IV, who received the composition of platelet-rich plasma and osteoplastic material mp3 OsteoBiol, demonstrated an increase in the number of the lesions of the periapical zone sized 1.6-10 mm2 in 1.7 times, while the number of the subjects with foci of bone destruction sized 11–20 mm2 and 21–30 mm2 lowered in 2.8 times and 2.0 times, respectively. In 3 months of the follow up period, the patients of group IV showed the values of Rtg scoring of bone tissues destruction in the apical area with a lesion area of 1.6-20 mm that averaged 2.13±0.10 scores and indicated a reduction of the periapical process by 1/3. The average Rtg score in the patients of group IV (0.92 ± 0.10 points) was significantly higher than in the individuals in groups I and II, p, p 1 <0.01, and was equal to the findings obtained in the individuals of the group III, p2 > 0.05. The relative indicator of bone tissue repair in this follow up was characterized by the minimum values in the individuals of groups I and II: 0.49 ± 0.05 and 0.57 ± 0.06, p <0.05, respectively. In the groups III and IV, the value of the relative indicators of bone tissue repair were significantly higher and scored 4.82 ± 0.54, p, p1 <0.01, and 6.94 ± 0.77, p, p1 <0.01, p2 < 0.05, respectively. At the same time, the average Rtg scoring in patients of group IV was significantly higher than in the participants of groups I and II, and was identical to the values in the subjects of group III. This study has demonstrated the successful outcomes of the treatment of dystrophic forms of apical periodontitis in the early follow up period when applying the composition based on platelet-rich plasma and osteoplastic material "mp3 OsteoBiol".

scholarly journals Dynamics of X-Ray Indicators in Patients with Destructive Forms of Apical Periodontitis in Long-Term Treatment

2021 ◽  
Vol 6 (3) ◽  
pp. 277-284
Author(s):  
Ju. Y. Lysokon ◽  
◽  
M. O. Iskiv ◽  
M. A. Luchinsky ◽  
◽  
...  
Keyword(s):  
Bone Tissue ◽  
Platelet Rich Plasma ◽  
Group Iv ◽  
Apical Periodontitis ◽  
X Rays ◽  
X Ray ◽  
Long Term Treatment ◽  
Half Axis ◽  
Apical Area

The purpose of the study was to evaluate the effectiveness of the proposed treatment based on changes in radiological parameters in patients with destructive forms of apical periodontitis in the long term. Materials and methods. During the study, 185 patients with destructive forms of apical periodontitis were examined and treated. They were divided into 4 groups. Measurements of the size of the lesion in the bone tissue (for lesions of round shape) were performed by the formula: S = πr2; for lesions of elliptical shape: S = π ab, where π = 3.14; r – the radius of the circle; a – the value of the major half-axis of the ellipse; b – the length of the small half-axis of the ellipse. Results and discussion. When evaluating X-rays pictures in the treating group IV, where ("Platelet-Rich Plasma + mp3 OsteoBiol") was used for root canal obturation, after 6 months of observation, in 19 people (40.43%) foci of destruction of the bone tissue of the apical area of 1.5 mm2 and less were visualized. It was characteristic of this group of persons that there was a decrease in their number of bone tissue destruction area in sizes: 1.6 - 20 mm2 – by 1.7 times; 21 - 30 mm2 – by 2.0 times; 31 - 40 mm2 – by 2.5 times; 41 - 51 and more mm2 – by 1.3 times. It should be noted that this trend convincingly demonstrates a significant reduction in bone tissue of the periapical area in patients of group IV, and indicates in favor of the adequacy of the applied therapy using our proposed osteotropic composition. X-ray evaluation of the results of treatment of patients of group IV, in whom for the treatment of destructive forms of apical periodontitis our proposed composition ("Platelet-Rich Plasma + mp3 OsteoBiol") was used, after 12 months of research showed that in 29 patients (61.70%) foci of destruction of the apical area were not visualized; in 14 people (29.79%) the foci of osteoporosis bone tissue in the apical area were 1.5 mm2 or less. At the same time, no lesions ranging in size from 1.6 mm2 to 30 mm2 were identified in the treated group IV. At the same time, we determined a decrease in the number of treated with lesion areas: 31 - 40 mm2 – by 2.0 times; 41 - 50 mm2 – by 3.0 times and 51 mm2 and more – by 1.5 times. After 12 months of follow-up in patients of group IV, Rtg score of bone destruction was 4.27±0.61 points, which was probably higher than in patients of I, II, p, p1 <0,01, and III study groups, p2 <0.05. It was noted that at the areas of destruction of cell tissue of the periapical area from 1.6 mm2 to 30 mm2, Rtg score with a value of 5.0±0.71 points, indicated a complete restoration of bone structure; from 31 mm2 to 50 mm2 – for the reduction of the periapical process more than 1/2 and for the area of 51 mm2 and more – for the reduction of the periapical process from 1/3 to 1/2

scholarly journals Clinical Outcome and 8-Year Follow-Up of Alveolar Bone Tissue Engineering for Severely Atrophic Alveolar Bone Using Autologous Bone Marrow Stromal Cells with Platelet-Rich Plasma and β-Tricalcium Phosphate Granules

2021 ◽  
Vol 10 (22) ◽  
pp. 5231
Author(s):  
Izumi Asahina ◽  
Hideaki Kagami ◽  
Hideki Agata ◽  
Masaki J. Honda ◽  
Yoshinori Sumita ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Marrow ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Bone Marrow Stromal Cells ◽  
Alveolar Bone ◽  
Platelet Rich Plasma ◽  
Long Term Follow Up

Background: Although bone tissue engineering for dentistry has been studied for many years, the clinical outcome for severe cases has not been established. Furthermore, there are limited numbers of studies that include long-term follow-up. In this study, the safety and efficacy of bone tissue engineering for patients with a severely atrophic alveolar bone were examined using autogenous bone marrow stromal cells (BMSCs), and the long-term stability was also evaluated. Methods: BMSCs from iliac bone marrow aspirate were cultured and expanded. Then, induced osteogenic cells were transplanted with autogenous platelet-rich plasma (PRP) and β-tricalcium phosphate granules (β-TCP) for maxillary sinus floor and alveolar ridge augmentation. Eight patients (two males and six females) with an average age of 54.2 years underwent cell transplantation. Safety was assessed by monitoring adverse events. Radiographic evaluation and bone biopsies were performed to evaluate the regenerated bone. Results: The major population of transplanted BMSCs belonged to the fraction of CD34−, CD45dim, and CD73+ cells, which was only 0.065% of the total bone marrow cells. Significant deviations were observed in cell growth and alkaline phosphatase activities among individuals. However, bone regeneration was observed in all patients and the average bone area in the biopsy samples was 41.9% 6 months following transplantation, although there were also significant deviations among each case. No adverse events related to the transplants were observed. In the regenerated bone, 27 out of 29 dental implants were integrated. Dental implants and regenerated bone were stable for an average follow-up period of 7 years and 10 months. Conclusions: Although individual variations were observed, the results showed that bone tissue engineering using BMSCs with PRP and β-TCP was feasible for patients with severe atrophic maxilla throughout a long-term follow-up period and was considered safe. However, further studies with a larger number of cases and controls to confirm the efficacy of BMSCs and the development of a protocol to establish a reproducible quality of stem cell-based graft material will be required.

scholarly journals Signal-averaged electrocardiogram in chronic Chagas' heart disease

1995 ◽  
Vol 113 (2) ◽  
pp. 851-857 ◽  
Author(s):  
Aguinaldo Pereira de Moraes ◽  
Paulo Jorge Moffa ◽  
Eduardo A. Sosa ◽  
Giovanni M. V. Bellotti ◽  
Carlos A. Pastore ◽  
...  
Keyword(s):  
Heart Disease ◽  
Time Domain Analysis ◽  
Group Iv ◽  
Root Mean Square Amplitude ◽  
Group Iii ◽  
Group I ◽  
Chagas Heart Disease ◽  
Group Ii ◽  
The Relationship

The aim of the study was to register the prevalence of late potentials (LP) in patients with chronic Chagas' heart disease (CCD) and the relationship with sustained ventricular tachycardia (SVT). 192 patients (96 males), mean age 42.9 years, with CCD were studied through a Signal Averaged ECG using time domain analysis. According to presence or absence of bundle branch block (BBB) and SVT, four groups of patients were created: Group I (n = 72): without SVT (VT-) and without BBB (BBB-): Group II (n = 27): with SVT (VT+) and BBB-; Group III (n = 63): VT- and with BBB (BBB+); and Group IV (N = 30): VT+ and BBB+. The LP was admitted, with 40 Hz filter, in the groups without BBB using standard criteria of the method. In the group with BBB, the root-mean-square amplitude of the last 40 ms (RMS) < =14µV was considered as an indicator of LP. RESULTS: In groups I and II, LP was present in 21 (78%) of the patients with SVT and in 22 (31%) of the patients without SVT (p < 0.001), with Sensitivity (S) 78%; Specificity (SP) 70% and Accuracy (Ac) 72%. LP was present in 30 (48%) of the patients without and 20 (67%) of the patients with SVT, in groups III and IV. p = 0.066, with S = 66%; SP = 52%; and Ac = 57%. In the follow-up, there were 4 deaths unrelated to arrhythmic events, all of them did not have LP. Eight (29,6%) of the patients from group II and 4 (13%) from group IV presented recurrence of SVT and 91,6% of these patients had LP. CONCLUSIONS: LP occurred in 77.7% of the patients with SVT and without BBB. In the groups with BBB, there was association of LP with SVT in 66,6% of the cases. The recurrence of SVT was present in 21% of the cases from which 91,6% had LP.

scholarly journals Gustatory dysfunction in relation to circumvallate papilla’s taste buds structure upon unilateral maxillary molar extraction in Wistar rats: an in vivo study

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 1667
Author(s):  
Sana Mostafa ◽  
Heba M. Hakam ◽  
Amal El-motayam
Keyword(s):  
Group Iv ◽  
Taste Buds ◽  
Group Iii ◽  
Maxillary Molars ◽  
Maxillary Molar ◽  
Underlying Mechanisms ◽  
Maxillary Molar Extraction ◽  
Taste Thresholds

Background: The interaction between taste sensation and dentoalveolar innervation is still under research.  teeth loss can alter taste thresholds in humans, but the underlying mechanisms are still obscure. This study investigated the effect of unilateral maxillary molars extraction on the structure of circumvallate papilla in rats. Methods: Thirty-two male Wister rats, aged 3-4 months were randomly distributed into four groups (one control and 3 experimental ) each including 8 animals. The rats were euthanized 3, 6 or 9 weeks following the procedure. The changes in trough length and the taste buds structure and number of both sides of CVP were investigated using routine histological examination followed by statistical analysis. Results: the trough toward the extraction side was obviously shorter with a noticeable decrease of taste buds’ number than the non-extraction side. Taste buds were reduced in size and most of them showed signs of degeneration which was more evident in group II followed by group III, less deformity detected in group IV in comparison to the preceding 2 experimental groups. the non-extraction side of all experimental groups showed normal trough length and generally normal histology of taste buds.  Conclusions: Maxillary molars extraction has a degenerative effect on the structure of  taste buds and gustatory epithelium which were more marked at the extraction side and showed improvement upon elongation of follow up period

scholarly journals The ability of platelet-rich plasma to regenerate a non-vital immature permanent teeth

2021 ◽  
Vol 24 (3) ◽  
Author(s):  
Salma Abdo ◽  
Amera Alkaisi
Keyword(s):  
Platelet Rich Plasma ◽  
Cold Test ◽  
Apical Periodontitis ◽  
Permanent Teeth ◽  
Pulp Chamber ◽  
Pulp Regeneration ◽  
Immature Teeth ◽  
Therapeutic Protocol ◽  
Regenerative Endodontic Treatment

Objectives: To test the ability of platelet-rich plasma clinically and radiologically for pulp regeneration of immature teeth with apical periodontitis. Material and Methods: An experimental study was conducted From (March/2018-July/2020)   12 upper central immature incisors with acute apical periodontitis and necrotic pulp from six patients receiving regenerative endodontic treatment using concentrated platelets rich plasma were performed by the same endodontist at Mediclinic Middle East Hospitals. Informed consent, including explanation of risks and alternative treatments or no treatment were prepared and filled by the patient parents. The therapeutic protocol was involved accessing the pulp chamber; irrigation copiously with sodium hypochlorite; applying calcium hydroxide as intracanal medicament and a provisionally sealing it after 4 weeks. The canal was cleaned, dried and injected with concentrated platelets rich plasma which serve as a scaffold for pulp regeneration. MTA was used to seal the chamber before final filling with composite.  Evaluations: All teeth were monitored clinically (mobility, palpation, percussion, and sensitivity cold test) and radiographically. Results: Twenty months follow-up all teeth showed resolution of periapical radiolucencies, continued root development with positive response to sensitivity cold test and no discoloration. Conclusion:  The results of this study confirmed the previous finding that pulp regeneration can be gained by using cPRP successfully   Keywords Immature teeth; Necrosis; cPRP; Regeneration.

scholarly journals Analysis of the length of fixation during hemivertebra resection. A monocentric cohort

2020 ◽  
Author(s):  
Sergey O Ryabykh ◽  
Egor Yu Filatov ◽  
Joseph Olorunsogo Mejabi ◽  
Dmitry M Savin ◽  
Alexander B Gubin
Keyword(s):  
Blood Loss ◽  
Cobb Angle ◽  
Spinal Deformity ◽  
Operating Time ◽  
Group Iv ◽  
Group Iii ◽  
Fixation Group ◽  
Group I ◽  
Segmental Fixation

Abstract Background: We aimed at reviewing results of surgical correction of spinal deformity due to hemivertebra with regard to length of instrumentation. Methods: Study comprised 117 patients with congenital spinal deformity treated between 2010 and 2018. Patients’ aged 1 to 18 years. Mean follow-up was 3 years (1 to 8). Posterior approach was used in all cases. Patients were subdivided into 4 groups. Result: Unilateral monosegmental fixation (Group I) for 15 children with mean age of 48.3 months. Cobb angle for scoliosis and kyphosis were 31.1 0 + 6.4 0 and 29.3° + 11.9 0 corrected to 7.8 0 + 6.8 0 and 4.7 0 + 4.0 0 respectively. Blood loss was 213.6 mL. Operating time was 165 minutes. Bilateral monosegmental fixation (Group II) for 24 patients with mean age of 53.1 months. Cobb angle for scoliosis and kyphosis were 32.5° + 8.6 0 and 30.9° + 4.3 0 corrected to 5.3 0 + 2.8 0 and 0.2 0 + 11.6 0 respectively. Blood loss was 215.4 mL. Operating time was 160.5 minutes. Bilateral three-segmental fixation (Group III) for 29 patients with mean age of 78.2 months. Cobb angle for scoliosis and kyphosis were 36.6° + 10.6 0 and 37.6° + 14.6 0 corrected to 6.2 0 + 6.1 0 and 5.0 0 + 5.2 0 respectively. Blood loss was 342.7 mL. Operating time was 197.0 minutes. Bilateral polysegmental fixation (Group IV) for 49 children with mean age of 112.7 months. Cobb angle for scoliosis and kyphosis were 40.2° + 14.8 0 and 58.2° + 35.6 0 corrected to 10.7 0 + 9.6 0 and 10.7 0 + 10.3 0 respectively. Blood loss was 549.3 mL. Operating time was 288.8 minutes. Conclusion: Choice of spinal fixation technique and the length of fixation were determined on the basis of patient’s age, magnitude of the deformity and concomitant vertebral abnormalities.

scholarly journals Osteointegración del aloinjerto crioconservado asociado a plasma enriquecido en plaquetas, en defectos óseos infectados. Estudio experimental

10.15417/187 ◽  
2013 ◽  
Vol 78 (2) ◽  
pp. 86
Author(s):  
Pablo Alexis Bruno ◽  
Damian Gabriel Bustos ◽  
Jorge Flores ◽  
Ignacio Fernandez Savoy ◽  
Natalia Gutierrez ◽  
...  
Keyword(s):  
Bone Formation ◽  
Platelet Rich Plasma ◽  
Bone Allograft ◽  
Group Iv ◽  
Title Page ◽  
Group Iii ◽  
Ct Evaluation ◽  
Pathologic Analysis ◽  
The Right ◽  
Los Grupos

<div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><span>R</span><span>ESUMEN<br /> </span><span>Introducción: </span><span>El objetivo de este trabajo experimental es determinar si el agregado de plasma rico en plaquetas influye en la osteointegración del aloinjerto crioconservado con antibióticos, en fracturas infectadas, con pérdida ósea, en huesos largos de conejos.</span></p><p><span>Materiales y métodos: </span><span>Se evaluaron cuatro grupos de 7 conejos cada uno, a los cuales se les generó una fractura infectada del fémur derecho. En los cuatro grupos, se colocó aloinjerto molido con antibiótico local, en el grupo II y en el grupo IV, se agregó también plasma rico en plaquetas. Se sacrificó a los grupos I y II, a los 30 días, y a los grupos III y IV, a los 90 días. Se realizó una evalua</span>ción histológica y tomográfica.</p><p>Resultados: Nueve conejos murieron en el período de estudio. No hubo diferencias estadísticamente significativas entre los grupos evaluados. En el grupo IV, con plasma rico en plaquetas, se observó neoformación ósea en tres de las cuatro muestras; se advirtieron sectores de acoplamiento entre el tejido receptor y el injertado, con consolidación en las imágenes tomográficas.</p><p>Conclusiones: En este trabajo, hubo correlación entre los resultados histológicos y tomográficos. Pese a que no se hallaron diferencias estadísticamente significativas, el agregado de plasma rico en plaquetas, además de estimular la generación de nuevos tejidos, disminuyó la reabsorción del tejido injertado al análisis anatomopatológico, y mostró mayor neoformación ósea y consolidación en el grupo IV (75%) tratado con plasma rico en plaque- tas que en el grupo III (25%) al que no se asoció plasma rico en plaquetas al aloinjerto óseo.</p></div><div class="column"><p><span>P</span><span>ALABRAS CLAVE</span><span>: Fracturas infectadas. Aloinjerto óseo. Plasma rico en plaquetas</span></p><p> </p><div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><span>O</span><span>SSEOINTEGRATION OF CRYOPRESERVED ALLOGRAFT ASSOCIATED WITH PLATELET</span><span>-</span><span>RICH PLASMA</span><span>, </span><span>IN INFECTED BONE DEFECTS</span><span>. E</span><span>XPERIMENTAL STUDY </span></p><p><span>A</span><span>BSTRACT<br /> </span><span>Blackground: </span><span>The objective of this experimental work was to determine whether the addition of platelet-rich plasma influences the osseointegraton of cryopreserved allograft with antibiotics in infected fractures with bone loss, in long bones of rabbits.</span></p><p><span>Methods: </span><span>Four groups of 7 rabbits with generated infected fracture of the right femur. Milled allograft with local antibiotic was placed in the four groups; groups II and IV also received platelet-rich plasma. Rabbits in groups I and II were sacrificed at 30 days, and those of groups III and IV at 90 days. Histological and CT evaluation was performed.</span></p><p><span>Results: </span><span>Nine rabbits died during the study period. There were no statistically significant differences between groups. In group IV with platelet-rich plasma, bone formation was observed in three of the four samples, with noticeable areas of coupling between the receiver and the grafted tissue with consolidation in CT.</span></p><p><span>Conclusions: </span><span>In our study, there was no correlation between the histological and tomographic findings. Although we found no statistically significant differences, the addition of platelet-rich plasma stimulated the generation of </span>new tissue, and also decreased reabsorption of the grafted tissue according to the pathologic analysis. Besides increased bone formation and consolidation was detected in group IV (75%) treated with platelet-rich plasma, compared to group III (25%) without platelet-rich plasma bone allograft.</p><div class="page" title="Page 2"><div class="layoutArea"><div class="column"><p><span>Key words: Infected fractures. Allograft bone. Platelet-rich plasma. </span></p></div></div></div><p> </p></div></div></div><p><span><br /></span></p></div></div></div><p> </p>

scholarly journals Analysis of the length of fixation during hemivertebra resection. A monocentric retrospective cohort

2020 ◽  
Author(s):  
Sergey O Ryabykh ◽  
Egor Yu Filatov ◽  
Joseph Olorunsogo Mejabi ◽  
Dmitry M Savin ◽  
Alexander B Gubin
Keyword(s):  
Blood Loss ◽  
Cobb Angle ◽  
Spinal Deformity ◽  
Operating Time ◽  
Group Iv ◽  
Group Iii ◽  
Fixation Group ◽  
Group I ◽  
Segmental Fixation

Abstract Background: We aimed at reviewing results of surgical correction of spinal deformity due to hemivertebra with regard to the age, severity of deformity and length of instrumentation.Methods. Study comprised 117 patients with congenital spinal deformity treated between 2010 and 2018. Patients’ aged 1 to 18 years. Mean follow-up was 3 years (1 to 8). Posterior approach was used in all cases. Patients were subdivided into 4 groups.Result:Unilateral mono-segmental fixation (Group I) for 15 children with mean age of 48.3 months. Cobb angle for scoliosis and kyphosis were 31.10 + 6.40 and 29.3° + 11.90 corrected to 7.80 + 6.80 and 4.70 + 4.00 respectively. Blood loss was 213.6 mL. Operating time was 165 minutes.Bilateral mono-segmental fixation (Group II) for 24 patients with mean age of 53.1 months. Cobb angle for scoliosis and kyphosis were 32.5° + 8.60 and 30.9° + 4.30 corrected to 5.30 + 2.80 and 0.20 + 11.60 respectively. Blood loss was 215.4 mL. Operating time was 160.5 minutes.Bilateral three-segmental fixation (Group III) for 29 patients with mean age of 78.2 months. Cobb angle for scoliosis and kyphosis were 36.6° + 10.60 and 37.6° + 14.60 corrected to 6.20 + 6.10 and 5.00 + 5.20 respectively. Blood loss was 342.7 mL. Operating time was 197.0 minutes.Bilateral poly-segmental fixation (Group IV) for 49 children with mean age of 112.7 months. Cobb angle for scoliosis and kyphosis were 40.2° + 14.80 and 58.2° + 35.60 corrected to 10.70 + 9.60 and 10.70 + 10.30 respectively. Blood loss was 549.3 mL. Operating time was 288.8 minutes.Conclusion: Choice of spinal fixation technique and the length of fixation were determined on the basis of patient’s age, magnitude of the deformity and concomitant vertebral abnormalities.

Clinical Follow-up of a Fissure Sealant Placed Using Different Adhesive Protocols: A 24-month Split-mouth Study

2018 ◽  
Vol 43 (4) ◽  
pp. 362-371 ◽  
Author(s):  
AR Yazici ◽  
E Ozturk Bayazit ◽  
ZB Kutuk ◽  
G Ozgunaltay ◽  
E Ergin ◽  
...  
Keyword(s):  
Retention Rate ◽  
Group Iv ◽  
Retention Rates ◽  
Fissure Sealant ◽  
Group Iii ◽  
Group I ◽  
Etch And Rinse ◽  
Acid Etch ◽  
Self Etch

SUMMARY The purpose of this study was to evaluate the retention rates of a fissure sealant placed using different adhesive protocols over 24 months. Twenty-four subjects with no restorations or caries received fissure sealants (Clinpro Sealant, 3M ESPE) placed using different adhesive protocols. A total of 292 sealants were placed as follows by two previously calibrated dentists using a table of random numbers (n=73): group I, acid-etch/without adhesive; group II, with a self-etch adhesive (Adper Easy Bond, 3M ESPE); group III, with an etch-and-rinse adhesive (Adper Single Bond 2, 3M ESPE); group IV, with acid + self-etch adhesive (Adper Easy Bond). Two other calibrated examiners independently evaluated the sealants at baseline and at six-, 12-, 18-, and 24-month recalls. Each sealant was evaluated in terms of caries formation being present or absent and retention using the following criteria: 1 = total retention, 2 = partial loss, and 3 = total loss. Pearson's χ2 test was used to evaluate differences in retention rates among the sealants for each evaluation period. At the end of 24 months, total retention rates were 57.5%, 27.4%, 84.9%, and 76.7% in the acid-etch, self-etch adhesive, etch-and-rinse adhesive, and acid + self-etch adhesive groups, respectively. Although there were no statistically significant differences between the retention rates among the adhesive protocols at 6 months (p=0.684), significant differences were observed at the 12-, 18-, and 24-month evaluations. At 24 months, the lowest retention rates were observed in the self-etch group (p&lt;0.05). No caries development was observed in any of the groups. The retention rate of sealants placed using self-etch adhesive was poor compared with the other groups.

scholarly journals Comparison of Surgical Outcomes with Time Interval of Operation among extradural haematoma (EDH) Patients

2018 ◽  
Vol 4 (1) ◽  
pp. 33-39
Author(s):  
MM Ehsanul Haque ◽  
Shamima Sultana ◽  
Md Saiful Alam ◽  
Wahida Begum ◽  
Syeda Asfiya Ara
Keyword(s):  
Surgical Intervention ◽  
Group Iv ◽  
Time Interval ◽  
Extradural Haematoma ◽  
Group Iii ◽  
Medical College ◽  
Group I ◽  
Study Population ◽  
Death Cases

Background: Post-operative outcome of extradural haematoma (EDH) patients depends on the time interval of operation.Objectives: The purpose of the present study was to evaluate the role of time interval and surgical intervention in EDH.Methodology: This interventional study was carried out in the Department of Neurosurgery at Dhaka Medical College and Hospital, Dhaka, Bangladesh from July 2001 to July 2003 for a period of two (02) years. Patients with the history of head trauma admitted in Neurosurgery unit of Dhaka Medical College and Hospital which were being diagnosed as EDH both clinically and radiologically were included as study population. All patients were treated surgically and haematoma was evacuated. Outcome regarding neurological status, functional recovery, associated morbidity and mortality were assessed in each case as per Glasgow Outcome Scale and was compared between the two groups of patients who were treated surgically within 3rd day and 4th to 7th day after infliction of injury. The study population was devided into 4 groups on the basis of the consciousness level on admission of the patients. The EDH patietns who had GCS <5, 5 to 8, 9 to 12 and 13 to 15 were categorized as group I, II, III and IV respectively. On the basis of pre operative time interval, surgical intervention was done within 3 days of injury and from 4th to 7th day of injury. Craniotomy and craniectomy were done depending on patient’s condition and situation of haematoma.Result: A total 63 patients were included. During admission out of 63 patients majority of the patients were in the group III which was 29(46%) cases. During pre-operqative period out of 63 patients majority of the patients were in the group III which was 30(47.6%) cases. Out of 63 cases a total number of 40 cases were performed the surgery within 72 hours and the rest 23 patients were from 4th day to 7th day of injury. In group I at 8th POD, 3 death cases were recorded at 3rd day operation group and 2 cases at 4th to 7th cases. In group IV at 8th POD follow up good recovery was reported in 6 cases at 3rd day and 3 cases at 4th to 7th day. In group I after 1 month, 3 death cases were recorded at 3rd day operation group and 2 cases at 4th to 7th cases. In group IV after 1 month follow up good recovery was reported in 6 cases at 3rd day and 3 cases at 4th to 7th day; however, moderate disability was reported in 2 cases at 4th to 7th day.Conclusion: In conclusion mortality rate is reduced in patients with EDH who are treated in the earliest possible time after head injuryJournal of National Institute of Neurosciences Bangladesh, 2018;4(1): 33-39

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