A study to determine angiographic findings in patients of acute coronary syndrome at teaching Hospital

Objective. We aim to evaluate the long-term prognosis of non-ST elevation acute coronary syndrome (NSTE-ACS) patients with high-risk coronary anatomy (HRCA). Background. Coronary disease severity is important for therapeutic decision-making and prognostication among patients presenting with NSTE-ACS. However, long-term outcome in patients undergoing percutaneous coronary intervention (PCI) with HRCA is still unknown. Method. NSTE-ACS patients undergoing PCI in Fuwai Hospital in 2013 were prospectively enrolled and subsequently divided into HRCA and low-risk coronary anatomy (LRCA) groups according to whether angiography complies with the HRCA definition. HRCA was defined as left main disease >50%, proximal LAD lesion >70%, or 2- to 3- vessel disease involving the LAD. Prognosis impact on 2-year and 5-year major adverse cardiovascular and cerebrovascular events (MACCE) is analyzed. Results. Out of 4,984 enrolled patients with NSTE-ACS, 3,752 patients belonged to the HRCA group, while 1,232 patients belonged to the LRCA group. Compared with the LRCA group, patients in the HRCA group had worse baseline characteristics including higher age, more comorbidities, and worse angiographic findings. Patients in the HRCA group had higher incidence of unplanned revascularization (2 years: 9.7% vs. 5.1%, p<0.001; 5 years: 15.4% vs. 10.3%, p<0.001), 2-year MACCE (13.1% vs. 8.8%, p<0.001), and 5-year death/MI/revascularization/stroke (23.0% vs. 18.4%, p=0.001). Kaplan–Meier survival analysis showed similar results. After adjusting for confounding factors, HRCA is independently associated with higher risk of revascularization (2 years: HR = 1.636, 95% CI: 1.225–2.186; 5 years: HR = 1.460, 95% CI: 1.186–1.798), 2-year MACCE (HR = 1.275, 95% CI = 1.019–1.596) and 5-year death/MI/revascularization/stroke (HR = 1.183, 95% CI: 1.010–1.385). Conclusion. In our large cohort of Chinese patients, HRCA is an independent risk factor for long-term unplanned revascularization and MACCE.

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Clinical characteristics and angiographic findings of non-ST-elevation acute coronary syndrome patients admitted with normal electrocardiogram

Journal of Electrocardiology ◽

10.1016/j.jelectrocard.2020.03.002 ◽

2020 ◽

Vol 60 ◽

pp. 77-81

Author(s):

Cayan Cakir ◽

Yemlihan Ceylan ◽

Ozgur Yasar Akbal ◽

Remzi Sarikaya ◽

Suleyman Barutcu

Keyword(s):

Acute Coronary Syndrome ◽

Clinical Characteristics ◽

Coronary Syndrome ◽

St Elevation ◽

Elevation Acute Coronary Syndrome ◽

Angiographic Findings

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Frequency of low levels of High Density Lipoprotein cholesterol in patients with acute coronary syndrome.

The Professional Medical Journal ◽

10.29309/tpmj/2019.26.12.1364 ◽

2019 ◽

Vol 26 (12) ◽

pp. 2054-2057

Author(s):

Muhammad Niaz Khan ◽

Tahir Ullah Khan ◽

Siraj Ud Din

Keyword(s):

Acute Coronary Syndrome ◽

Teaching Hospital ◽

Sample Size Calculation ◽

Density Lipoprotein ◽

Female Gender ◽

High Density ◽

High Density Lipoproteins ◽

Cross Sectional ◽

Coronary Syndrome ◽

Low Hdl

To find out frequency of low HDL-C levels in patients suffering from acute coronary syndrome. Study Design: Descriptive cross sectional study. Setting: Department of cardiology Khyber Teaching Hospital (KTH) Peshawar. Period: 04/04/2016 to 04/10/2016. Material & Methods: By applying WHO formula for sample size calculation and 95% confidence interval, a total of 154 Patients admitted to coronary care unit (CCU) of Khyber Teaching Hospital with acute coronary syndrome were selected. Anticipated portion of low HDL in ACS was 73.3 % and absolute precision of about 7%. Results: In this study, mean age was 55.720 ± 8.901 years. About 38% patients were of female gender while 62% patients were male. About 20 % patients had UA, 9% patients had NSTEMI, and 71% patients had STEMI. Patients with low high density lipoproteins constituted about 48% of the total patients admitted with ACS. Conclusion: Our study concluded that significant number (48%) of patients with ACS had low HDL levels.

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Acute coronary syndrome-related mortality audit in a teaching hospital at Port Blair, India

Journal of Family Medicine and Primary Care ◽

10.4103/2249-4863.222033 ◽

2017 ◽

Vol 6 (3) ◽

pp. 502 ◽

Cited By ~ 2

Author(s):

SwapanKumar Paul ◽

ShivShankar Singh ◽

Ranabir Pal ◽

PandurangVithal Thatkar

Keyword(s):

Acute Coronary Syndrome ◽

Teaching Hospital ◽

Coronary Syndrome ◽

Related Mortality

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IMPACT OF GENDER ON THE CLINICAL FEATURES, ANGIOGRAPHIC FINDINGS, AND OUTCOMES OF YOUNG PATIENTS PRESENTED WITH ACUTE CORONARY SYNDROME

Pakistan Heart Journal ◽

10.47144/phj.v54i4.2186 ◽

2022 ◽

Vol 54 (4) ◽

pp. 321-327

Author(s):

Kamran Ahmed Khan ◽

Dileep Kumar ◽

Ayaz Hussain Shaikh ◽

Sanam Khowaja ◽

Mehboob Ali ◽

...

Keyword(s):

Myocardial Infarction ◽

Acute Coronary Syndrome ◽

Symptom Onset ◽

Young Patients ◽

Cross Sectional ◽

Men And Women ◽

St Segment Elevation ◽

Coronary Syndrome ◽

Significant Difference ◽

Angiographic Findings

Objectives: Acute coronary syndrome (ACS) at a younger age is now becoming a crucial problem. This study determined the effect of gender on the clinical findings and outcomes of young patients (≤ 45 years) with ACS. Methodology: In this descriptive cross sectional study, young patients (≤45 years) who presented with ACS and underwent coronary angiography were recruited. The comparison of clinical profile, angiographic findings, in-hospital, and 90-days mortality between genders were made. Results: A total of 335 young patients with ACS were included, 80.6% of whom were men. A significant difference was found between men and women in terms of mean age: 38±6 vs. 40±5 (p=0.014), hypertension: 37.8% vs. 58.5% (p=0.002), diabetes: 17.4% vs. 35.4% (p=0.001), smoking: 50.4% vs. 6.2% (p≤0.001), use of smokeless tobacco: 14.1% vs. 4.6% (p=0.037), median time from symptom onset to first medical contact: 270 [420–165] minutes vs. 346 [499.5–240] minutes (p=0.047), ST-segment elevation myocardial infarction (STEMI) 89.6% vs. 78.5% (p=0.015), non-ST-elevation myocardial infarction (NSTEMI) 8.5% vs. 18.5% (p=0.019), and three-vessel disease (3VD) 10.7% vs. 21.5% (p=0.019), respectively. In-hospital and 90-day mortality rates were 0.4% vs. 3.1% (p=0.097) and 1.5% vs. 4.6% (p=0.136) for men and women, respectively. Conclusion: Women tended to have a higher age at presentation, more frequent traditional risk factors, late presentation after symptom onset, frequent NSTEMI, and 3VD, whereas men were distinct with frequent STEMI and higher tobacco use. In addition, women trended to have a higher in-hospital as well as short-term mortality than men did.

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