scholarly journals Disparity in Populace Phenotype Impels Predisposition to Variations in Health Status

2021 ◽  
Vol 11 (3) ◽  
pp. 136-142
Author(s):  
Hira Maqsood

Background: The disparity in populace phenotype, embracing stature and pigmentation, drives of internal physiological constituent and adaptation to the external environment, impel variations in populace health status. The study tends to explore how significantly populaces phenotype influenced by internal or external exposures, and how effectually it prognosticates predisposition to variant health states. Methods: Ecological study encompassing twenty states residing on antipodes (North and South) endures distinct exposures, exhibit disparate phenotypes, execute different health status. Each State selected employing non-proportion quota sampling, standing extreme on either stature or pigmentation, residing in cold or hot region, contrasted on considered variables embracing UV-index, malnutrition, healthy life expectancy, fertility rate, natural increase, and top five causes of mortality. All computation, analysis, and interpretation perform employing MS-EXCEL. The complete compilation phase last from March to June 2019. Results: Findings reveal a strong association between exposures and phenotypes, UV-index and pigmentation (r = 0.96), malnutrition and stature (r = -0.81). Stature descends and pigmentation ascends along the latitude (North to South). Populace light pigmentation tall stature executes healthy prolong life span contrast to deep pigmentation standing short. Cardiac and cancer diseases significantly reported among statured nations. While high susceptibility to Influenza/ Pneumonia, and HIV/AIDS observe in pigmented nations. Conclusion: Decisively homo sapiens phenotypes inordinately servile to internal and external exposures effectually prognosticate predisposition to distinct health states. Enforcement of measures mitigating populace internal and external exposure can elicit desire output in phenotype and outcomes in health status.

2009 ◽  
Vol 54 (8) ◽  
pp. 526-533 ◽  
Author(s):  
Norbert Schmitz ◽  
Alain Lesage ◽  
JianLi Wang

Objective: Psychological distress questionnaires are often used as screening instruments for mental disorders in clinical and epidemiologic settings. Poor physical health may affect the screening properties of a questionnaire. We evaluate the effect of self-perceived health status on the screening performance of the Kessler K10 and K6 scales in a community sample. Methods: We used data from the Canadian Community Health Survey: Mental Health and Well-Being (CCHS 1.2). Psychological distress was measured by the 6–item (K6) and the 10–item (K10) Kessler instrument. Depression and anxiety disorders were assessed using the World Mental Health Composite International Diagnostic Interview (1–month estimates). Optimal cut-off points regarding health status were determined by finding the K6 and K10 values that allowed for the best balance between sensitivity and specificity. Stratum-specific likelihood ratios (SSLRs) were computed to define strata with discriminating power. Results: There was a strong association between the screening performance of the K6 and K10 scales and self-perceived health status: for the K10 scale, a cut-off point of 5/6 yielded the best balance between sensitivity and specificity for subjects with excellent or very good health status, while a cut-off point of 14/15 yielded the best balance between sensitivity and specificity for subjects with poor health status. Conclusions: The combination of the K6 and K10 scales, with a self-rated health status item, may improve screening properties of the 2 scales.


2019 ◽  
pp. 24-28
Author(s):  
Santanu Sen Roy ◽  
Debasis Mitra ◽  
Aakansha Malawat ◽  
Dibyendu Kr. Kundu ◽  
Abhijit Chakraborty ◽  
...  

INTRODUCTION: Periodontal disease is a chronic inflammatory disease that affects the majority of the world's population. Currently, more emphasis has been directed towards the combined influence of education level, lifestyle instead of regular risk factors in dealing with chronic illnesses. The present paper is to assess the periodontal health status, education level and lifestyle in outpatient department of Guru Nanak Institute of Dental Sciences and Research (GNIDSR), Sodepur, Kolkata, West Bengal. OBJECTIVE:The objective of the study was to evaluate patient's education level & life style with periodontal disease. METHODOLOGY: This cross-sectional study was conducted on 245 subjects of 35-44 years age group over two months period. Subjects were interviewed by the questionnaire and Modified Community Periodontal Index was recorded. RESULT: The statistical analysis shows significant decrease in periodontal health status when education level increased. Also the prevalence of periodontitis with a healthy lifestyle is significantly lower when compared with an unhealthy lifestyle. CONCLUSION:There is a strong association of lifestyle and education level with periodontal health.


2000 ◽  
Vol 18 (18) ◽  
pp. 3280-3287 ◽  
Author(s):  
Ronald D. Barr ◽  
Dawn Chalmers ◽  
Sonja De Pauw ◽  
William Furlong ◽  
Sheila Weitzman ◽  
...  

PURPOSE: In pediatric oncology, Wilms’ tumor and advanced neuroblastoma represent opposite ends of the spectra of survival probability and therapeutic intensity. Consequently, it was envisaged that survivors of Wilms’ tumor would enjoy better health status and health-related quality of life (HRQL) than survivors of advanced neuroblastoma. PATIENTS AND METHODS: Health status questionnaires were sent to the parents of all eligible children and to the children themselves if they were ≥ 8 years of age. Responses were received from 84% of 93 eligible families. Responses were converted by established algorithms into levels of two multiattribute health status classification systems known as Health Utilities Index Mark 2 and Mark 3. These systems are linked to measures of preference, in the form of multiattribute utility functions, which provide scores of morbidity for single-attribute levels and of global HRQL for comprehensive health states. RESULTS: A greater burden of morbidity was identified in the survivors of advanced neuroblastoma than in survivors of Wilms’ tumor based on the assessments of the parents of these children. In particular, survivors of advanced neuroblastoma exhibited deficits in hearing and speech. It is possible that this morbidity burden reflects the prevalent use of platinum compounds (causing ototoxicity) in this group. Within parent-child dyads there was a high level of percentage agreement on responses in all attributes except cognition. CONCLUSION: Extension of this study to a larger sample size of patients will provide clarification of these observations.


2018 ◽  
Vol 18 (4) ◽  
pp. 624
Author(s):  
Dino Eka Putra ◽  
Sarbaini Anwar ◽  
Tinda Afriani

This study aimed to determine the potential of buffaloes in Ulakan Tapakis sub-district to produce calves and its viability as a source buffaloes. Casus and questionnaire are used in this study in which three sub-district characterized by high, medium and low buffalo population are chosen quota sampling. The observed variables in this study are the identity of the breeder and the buffalo. The development of buffalo population was analyzed using breeding theory approach. The average increase of the population was analyzed using a time series analysis. The results showed that Net Replacement Rate (NRR) value in male and female of 157.31% and 191.27% and the natural increase (NI) value of 23.66% indicating a moderate increase of the population. This study also shows that the population of buffaloes in the region is sufficient to cover its need. Male and female seed potencial of 4.55% and 5.33% of the population. On average the increase population of buffalo from 2011 to 2015 annual of as much as 172.75 head or 16.53%. Estimated population of buffaloes in 2016 and 2020 as in 1675 head and 2183 head eith average increase population as much as 63 head or 3.40%.


2015 ◽  
Vol 2 (3) ◽  
pp. 222-226
Author(s):  
Nizar Argyatiyasa ◽  
Suprajitno Suprajitno ◽  
Wiwin Martiningsih

Elderly experience physical changes, mental changes, psychosocial changes that would affectthe elderly healthy lifestyle. The Method used descriptive design. The population in this researchwere the elderly who were registered in the territory UPTD Posyandu Health Sukorejo Blitar City in1493 as the elderly, and the samples taken were 94 elderly Using quota sampling technique. The datawas collected by interview based on a questionnaire. The data collection was conducted on 18 Mayuntil 18 June 2014. The results showed that the Healthy Lifestyle in the posyandu of elderly in regionUPTD Healt Sukorejo Blitar City was good 72.3% (68 elderly). According to the Indonesia Republichealthy Deepartement (1997) in Udayana Psychology of journal (2013), defines a healthy lifestyleattempt to implement good practice in creating a healthy lifestyle and avoid bad habits that can affecthealth. Researchers found elderly efforts in maintaining the health status most of the elderly was optimal,it indicates that the elderly realize the importance of creating a healthy lifestyle.


Author(s):  
Erik Nord

AbstractIn the last two decades a number of health status index models have been developed for assessing the value of health outcomes in terms of quality-adjusted life years. The models can be tested by comparing their implications with direct observations of how societies think resources should be distributed across patient groups. This paper reviews empirical evidence of this kind from various countries and summarizes the evidence in three rules of thumb for selecting values for health states. Nine different models are judged relative to these rules of thumb. Eight of the models underestimate the strength of social preferences for treating the severely ill before the less severely ill. The ninth has a strong bias against states associated with emotional distress. As a consequence, none of the models can be seen as sufficient stand-alone instruments for valuing health outcomes. Instead, the models may be seen as complementary and adjustable parts of a tool kit that should also include the rules of thumb suggested in this paper.


2020 ◽  
Vol 49 (5) ◽  
pp. 1739-1748
Author(s):  
Damien Bricard ◽  
Florence Jusot ◽  
Alain Trannoy ◽  
Sandy Tubeuf

Abstract Objective We assess the existence of unfair inequalities in health and death using the normative framework of inequality of opportunities, from birth to middle age in Great Britain. Methods We use data from the 1958 National Child Development Study, which provides a unique opportunity to observe individual health from birth to the age of 54, including the occurrence of mortality. We measure health status combining self-assessed health and mortality. We compare and statistically test the differences between the cumulative distribution functions of health status at each age according to one childhood circumstance beyond people’s control: the father’s occupation. Results At all ages, individuals born to a ‘professional’, ‘senior manager or technician’ father report a better health status and have a lower mortality rate than individuals born to ‘skilled’, ‘partly skilled’ or ‘unskilled’ manual workers and individuals without a father at birth. The gap in the probability to report good health between individuals born into high social backgrounds compared with low, increases from 12 percentage points at age 23 to 26 at age 54. Health gaps are even more marked in health states at the bottom of the health distribution when mortality is combined with self-assessed health. Conclusions There is increasing inequality of opportunities in health over the lifespan in Great Britain. The tag of social background intensifies as individuals get older. Finally, there is added analytical value to combining mortality with self-assessed health when measuring health inequalities.


BMJ Open ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. e034683
Author(s):  
Tonya Moen Hansen ◽  
Ylva Helland ◽  
Liv Ariane Augestad ◽  
Kim Rand ◽  
Knut Stavem ◽  
...  

IntroductionNorway is one of several European countries that lacks a national value set and scoring algorithm for the EuroQol five dimensions (EQ-5D). Recent studies have found differences between countries in terms of health values or preferences for health states described by instruments such as the EQ-5D. The project aims to model a national value set for the five level version of the EQ-5D based on values elicited from a representative sample of the Norwegian adult general population in terms of region, age, sex and level of education. Using a sampling strategy supporting the collection of values for both hypothetical and experienced health states, the study will have the additional aim of assessing the feasibility of collecting experience-based values in accordance with the latest EQ-5D valuation study protocol, and comparing values with those given for hypothetical health states.Methods and analysisMultistage random sampling and quota-sampling will contribute to representativeness. To increase the number of valuations of experienced health states, those with less than perfect health will be oversampled, increasing the total number of interviews from 1000 to 1300–1500. The most recent EQ-5D valuation protocol will be followed which includes computer assisted face-to-face, one-to-one interviews and use of composite time trade-off and discrete choice experiments.Ethics and disseminationThe study has been reviewed and found to be outside of the scope of the ethics committee and thus not in need of ethical approval. The study findings will be disseminated through peer-reviewed publications, conference presentations and summaries for key stakeholders and partners in the field. The scoring algorithms will be available for widely used statistical software.


Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 3329-3329
Author(s):  
Jessica D. Friedlich ◽  
Matthew C. Cheung ◽  
Kevin R. Imrie ◽  
Brigette Hales ◽  
Nicole Mittmann ◽  
...  

Abstract Introduction: Health utilities (HU) elicited directly from patients have immediate application in facilitating medical decision-making and cost-effectiveness determinations. Collection of HU using generic health status scales enable comparisons across diseases, but may not be sensitive to variations in health states within a particular disease. The EuroQOL EQ5D is a generic scale that has never been used to generate utilities in a broad spectrum of follicular/indolent lymphoma patients and has not been validated in this context. Methods: A consecutive, cross-sectional cohort of patients attending an outpatient malignant hematology clinic at a major cancer centre (Toronto, Canada) represented the eligible study population. Patients with a diagnosis of FL or other indolent NHL who consented to the study were asked to complete demographic and disease specific questionnaires in addition to the EuroQOL EQ-5D and Functional Assessment of Cancer Therapy (FACT)-Lymphoma quality of life assessment tools. Results: Eighty-four patients completed the survey study (>95% response rate). Mean age was 58.7 (+/− 13.8 SD) and 55% were male. Diagnoses included FL (55%), CLL (25%), and other indolent NHL (20%). The majority of patients presented in advanced stage (stage III–IV; 65%) and had received some therapy to date, although 29% were still being observed at the time of survey administration. The mean utility score for the population was 0.84 (+/− 0.24; range 0–1). We evaluated the construct that patients receiving active treatment and those who were not in remission would have lower utility scores. Indeed, utilities were higher in patients being observed (0.91 +/− 0.16) compared to those in first remission (0.84 +/− 0.25), subsequent remissions (0.81 +/− 0.20), or those who were receiving active chemotherapy (0.75 +/− 0.27; p=0.049). Patients who were being followed in ongoing remission also trended to higher health status values (mean 0.88 +/− 0.21) compared to those who were not in remission (0.80 +/− 0.22; p=0.15). Utilities elicited from the EQ5D showed a moderate correlation with a criterion measure of quality of life, the FACT-Lymphoma scale (Spearman correlation coefficient 0.54, p<0.0001). Conclusions: Utilities from the EQ5D are able to discriminate various health states in patients with follicular and other indolent lymphomas and the scale demonstrates construct and criterion validity in this population. HU scores are particularly sensitive to changes in patient remission and treatment status.


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