scholarly journals A 87 YEARS OLD MALE WITH GIANT PROSTATIC HYPERPLASIA AND BLADDER STONES, THE LARGEST PROSTATE REPORTED IN INDONESIA

2017 ◽  
Vol 24 (2) ◽  
Author(s):  
Vera Vera ◽  
Sawkar Vijay Pramod
Keyword(s):  
Body Mass Index ◽  
Benign Prostate Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Chief Complaint ◽  
Median Lobe ◽  
Prostate Hyperplasia ◽  
Case Presentation ◽  
Prostate Weight ◽  
Large Prostate ◽  
Benign Prostate

Objective: The aim of this article is to report a case of Giant Prostatic Hyperplasia and see the correlation between volume of prostate and benign prostate hyperplasia (BPH) symptoms. Giant BPH is defined as a prostate weight over 200 g or 500 g; the lower threshold was suggested by Japanese authors. It’s extremely rare, with only 16 cases exceeding 500 g till 2013. Case presentation: Patient was an 87-year-old male with chief complaint of haematuria. We performed Transabdominal Ultra Sonography (USG) on the patient. Discussion: Transabdominal USG showed enlarged prostate with median lobe protruding into the bladder measuring 86 x 102 x 76 mm and 348 cc in volume. We performed transvesical prostatectomy. The large prostate was enucleated completely in one piece with 23 stones measuring about 1 cm in size. Grossly, the mass measured 12 x 8 cm and weighed 300 g. Histopathology evaluation revealed BPH. Conclusion: To our knowledge, this is the first giant BPH case being reported in Indonesia. We would like to emphasize that severity of BPH symptoms does not correlate with volume of the prostate. Unfortunately, we can not conclude that there were correlation between body mass index (BMI) and volume due to lack of BMI data from the literature.

scholarly journals Periodontal disease and risk of benign prostate hyperplasia: a cross-sectional study

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Lan Wu ◽  
Bing-Hui Li ◽  
Yun-Yun Wang ◽  
Chao-Yang Wang ◽  
Hao Zi ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Periodontal Disease ◽  
Subgroup Analysis ◽  
Benign Prostate Hyperplasia ◽  
Prostate Volume ◽  
Prostatic Hyperplasia ◽  
Health Examination ◽  
Control Analysis ◽  
Prostate Hyperplasia ◽  
Benign Prostate

Abstract Background Both periodontal disease and benign prostatic hyperplasia are age-related diseases that affect millions of people worldwide. Hence, this study aimed to investigate the association between periodontal disease and the risk of benign prostatic hyperplasia. Methods A total of 4930 participants were selected from an available health examination that was carried out in 2017, only males were considered for further analysis. All eligible males were divided into benign prostatic hyperplasia and normal groups, the benign prostatic hyperplasia group was then divided into prostate volume ≤ 60 g and > 60 g subgroups; all their periodontal status was extracted and then into normal (CPI score of 0), periodontal disease (CPI score between 1 and 4), and periodontitis (CPI score between 3 and 4) groups. The correlation between periodontal disease and benign prostatic hyperplasia was investigated using logistic regression analyses and greedy matching case-control analysis. Subgroup analysis based on prostate volume was also performed. All analyses were conducted with SAS 9.4 software. Results A total of 2171 males were selected for this analysis. The presence of periodontal disease significantly increased the risk of benign prostatic hyperplasia by 1.68 times (OR = 1.68, 95% CI: 1.26–2.24), and individuals with periodontitis showed a higher risk (OR = 4.18, 95% CI: 2.75–6.35). In addition, among matched cases and controls, this association remained robust (periodontal disease: OR = 1.85, 95% CI: 1.30–2.64; periodontitis: OR = 4.83, 95% CI: 2.57–9.07). Subgroup analysis revealed that periodontal disease significantly increased benign prostate hyperplasia risk as well (for prostate volume ≤ 60 g: OR = 1.64, 95% CI: 1.22–2.20; for volume > 60 g: OR = 2.17, 95% CI: 1.04–4.53), and there was a higher risk in the group with a prostate volume greater than 60 g. Conclusion Periodontal disease is significantly and positively associated with an increased risk of benign prostatic hyperplasia. Further validation studies should be performed to explore the relationship between periodontal treatment and benign prostate hyperplasia.

Inhibitory Effect of Artemisinin on Testosterone Propionate Induced Benign Prostatic Hyperplasia

2020 ◽  
Vol 17 ◽  
Author(s):  
Ayushi Solanki ◽  
Sandip Patel ◽  
Nilay Solanki ◽  
Umang Shah
Keyword(s):  
Testosterone Propionate ◽  
Benign Prostate Hyperplasia ◽  
Treated Group ◽  
Albino Rats ◽  
Prostate Hyperplasia ◽  
Prostate Weight ◽  
Group I ◽  
Study Results ◽  
Group Ii ◽  
Benign Prostate

Background/Objective: Benign prostate hyperplasia (BPH) is an abnormal growth of prostate observed commonly in elderly males. Artemisinin has been reported to reduce the levels of testosterone. This study is designed to evaluate the efficacy of Artemisinin on testosterone propionate (TP) induced benign prostate hyperplasia. Materials and methods: Male wistar albino rats (n=24) were separated into four groups of six rats each. Group I was served as control and distilled water using tween 80 an emulsifying agent was administered subcutaneously. BPH was induced by testosterone propionate 3mg/kg (Group II), S.C. daily for 28 days. Group III was BPH + Finasteride treated group (10mg/kg orally for 28 days) and BPH + Artemisinin treated group (Group IV) (50 mg/kg orally for 28 days). Result: The study results showed significantly high levels of serum prostatic acid phosphatase (PAP), lactate dehydrogenase (LDH) and an elevation in prostate weight and prostatic index in Group II (BPH) when compared with Group I. The histopathological examination showed an increase in the epithelial proliferation of prostatic cells with involutions protruding into the lumen in BPH group when compared to the normal group. Treatment with Artemisinin (50 mg/kg) reduced the levels of PAP, LDH, prostate weight and prostatic index to a significant extent and restored the histoarchitectural features of the cells. Conclusion: The present study concludes that the Artemisinin is efficacious in testosterone propionate induced BPH. This could be attributed, at least partly, to its anti-inflammatory property or its role in testosterone level reduction or as a Vitamin D receptor modulator.

scholarly journals Study on Estimation of Serum Prostate Specific Antigen Level and Prostate Volume with Trans-Abdominal Ultrasonography Finding in Benign Prostate Hypertrophy at Tertiary Care Hospital : A Cross Sectional Descriptive Study

2021 ◽  
Vol 6 (2) ◽  
pp. 1556-1560
Author(s):  
Chandra Prakash Gaire
Keyword(s):  
Prostate Specific Antigen ◽  
Benign Prostate Hyperplasia ◽  
Prostate Volume ◽  
Specific Antigen ◽  
Prostatic Hyperplasia ◽  
Prostate Specific Antigen Level ◽  
Age Group ◽  
Antigen Level ◽  
Prostate Hyperplasia ◽  
Benign Prostate

Introduction: The periurethral and transition zones of the prostatic gland develop benign prostatic hyperplasia and represent an inevitable phenomenon for the ageing male population. Prostatic specific antigen, is a serine protease, level rises in the blood if the barrier between thelining epithelium and the blood stream is damaged. Benign prostatic hyperplasia, prostatic carcinoma and prostatitis are three common diseases where PSA in the serum is raised. Prostate volume also increases according to age, which can be estimated by trans-abdominal ultrasonography. Objective: The aim of the study is to estimate the PSA level in blood and its relationship with prostate volume in benign prostatic hyperplasia patients. Methodology: It is a descriptive cross-sectional study which was carried out between a periods of 1st April 2018 to 31st March 2019 at Birat Medical College Teaching Hospital. All the patients diagnosed with benign prostate hyperplasia at the department of urology were included in the study. Blood samples of patients were analyzed for Prostate specific antigen level estimation by chemiluminescence immunosorbent assay. Prostatic volume of the patients was measured by Transabdominal ultrasound technique. Data were entered and analyzed in Microsoft Excel. Results: A total of 68 patients were diagnosed with benign prostate hyperplasia. The mean age of the patients was 61.8±12.3 years. The maximum number 23 of patients with BPH was there in age group 51-60. The maximum no of patients 38 were having their PSA level between the range of 4.0-10.0 ng/ml. The maximum no of patients 28 was having Prostate volume in the range of 40-60 gm. The maximum number of patients 31 was having diabetes mellitus as a co-morbid association. The maximum mean PSA level and prostate volume in the patients were observed in age group >80 years,which was 20.1±8.6 ng/ml and >80 gm respectively. Conclusion: The prostate specific antigen level and prostate volume both increase in advance age group of patients suffering with benign prostate hyperplasia.

Antrodan, A β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia

2015 ◽  
Vol 6 (2) ◽  
pp. 635-645 ◽  
Author(s):  
Chiung-Chi Peng ◽  
Yi-Ting Lin ◽  
Kuan-Chou Chen ◽  
Charng-Cherng Chyau ◽  
Robert Y. Peng
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Benign Prostate Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Common Disease ◽  
Prostate Hyperplasia ◽  
Antrodia Cinnamomea ◽  
Benign Prostate

Benign prostatic hyperplasia (BPH), one of the most common disease usually occurring in men in their 50s, has now become an atypical direct cause of mortality.

989 Body mass index predicts failure of surgical management in benign prostate hyperplasia

2013 ◽  
Vol 12 (1) ◽  
pp. e989
Author(s):  
J.M. Willder ◽  
V. Walker ◽  
G.L. Halbert ◽  
C.P.C. Dick ◽  
C. Orange ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Surgical Management ◽  
Benign Prostate Hyperplasia ◽  
Prostate Hyperplasia ◽  
Benign Prostate

scholarly journals The Significance of PSA/IGF-1 Ratio in Differentiating Benign Prostate Hyperplasia from Prostate Cancer

2000 ◽  
Vol 16 (3-4) ◽  
pp. 143-146 ◽  
Author(s):  
G. Koliakos ◽  
D. Chatzivasiliou ◽  
Th. Dimopoulos ◽  
V. Trachana ◽  
K. Paschalidou ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Roc Analysis ◽  
Benign Prostate Hyperplasia ◽  
Specific Antigen ◽  
Prostatic Hyperplasia ◽  
Prostate Hyperplasia ◽  
Patients With Cancer ◽  
Free Psa ◽  
Benign Prostate

The importance of insulin-like growth factor 1 (IGF-1) in human serum for the early diagnosis of prostate cancer is controversial. The IGF-1/PSA ratio may improve the performance of prostate specific antigen (PSA) as a prostate cancer marker. IGF-1, along with PSA and free PSA concentration, was measured in the serum of 34 patients with prostate cancer and in 131 patients with benign prostatic hyperplasia (BPH). Although IGF-1 concentration did not significantly differ between the groups, PSA/IGF-1 ratio could clearly distinguish the two groups. In patients with cancer but not in patients with BPH, IGF-1 concentration correlated with PSA and free PSA. The values of PSA and free PSA correlated with each other for both groups. Receivers Operating Curve (ROC) analysis indicated a better sensitivity to specificity ratio for PSA/IGF-1 than for PSA or Free/Total (F/T) PSA.

scholarly journals HIGH POWER TRANSURETHRAL THULIUM:YAG LASER VAPOENUCLEATION OF PROSTATE – A NEW STANDARD IN BENIGN PROSTATE HYPERPLASIA SURGERY

InterConf ◽  
2021 ◽  
pp. 281-289
Author(s):  
Alexei Plesacov ◽  
Ivan Vladanov ◽  
Vitalii Ghicavii
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
High Power ◽  
Benign Prostate Hyperplasia ◽  
Postoperative Recovery ◽  
Minimal Invasive ◽  
Prostatic Hyperplasia ◽  
Surgical Trauma ◽  
Prostate Hyperplasia ◽  
Invasive Techniques ◽  
Benign Prostate

According to current reccomandations, open adenomectomy is considered the most efficient surgical option for patients with large benign prostatic hyperplasia. In order to reduce surgical trauma and to improuve postoperative recovery, there have been proposed several minimally invasive techniques for the treatment of large benign prostatic hyperplasia, the most innovative being laser surgery. High power Thulium:YAG laser vapoenucleation of prostate is becoming popular for minimal invasive surgical management of benign prostate hyperplasia.

HUBUNGAN USIA, OBESITAS DAN RIWAYAT PENYAKIT DIABETES MELLITUS DENGAN KEJADIAN BENIGN PROSTATE HYPERPLASIA (BPH) DERAJAT IV DI RSUD DR. M. HAULUSSY AMBON PERIODE 2012-2014

2017 ◽  
pp. 141-151
Author(s):  
Andrew Ruspanah
Keyword(s):  
Diabetes Mellitus ◽  
Benign Prostate Hyperplasia ◽  
Chi Square ◽  
Cross Sectional ◽  
Prostate Hyperplasia ◽  
Benign Prostate

Pendahuluan. Benign Postate Hiperplasia (BPH) adalah penyakit yang umumnya terjadi pada pria lansia yang disebabkan oleh penuaan. Hiperplasia prostat adalah pertumbuhan jaringan nodul fibroadenomatosa pada prostat. Pembesaran prostat jinak merupakan penyakit yang tersering kedua setelah batu saluran kemih didapatkan secara klinis di Indonesia. Tujuan. Penelitian ini bertujuan untuk mengetahui hubungan antara usia, obesitas dan riwayat diabetes mellitus dengan kejadian Benign Prostate Hyperplasia (BPH) grade IV di Rumah Sakit Dr. M. Haulussy Ambon periode 2012-2014. Metode. Jenis penelitian ini adalah penelitian analitik desain Cross-Sectional, dengan menggunakan catatan medis data di ruang operasi di Rumah Sakit Dr. M. Haulussy Ambon Tahun 2012-2014 dan memperoleh jumlah sampel yang memenuhi kriteria inklusi sebanyak 239, yang diambil dengan teknik total sampling. Analisis dilakukan dengan analisis univariat dan bivariat menggunakan uji Chi Square. Hasil yang di temukan dalam penelitian ini bahwa kejadian BPH lebih besar pada mereka yang berusia> 65 tahun dan 56-65 tahun dibandingkan dengan usia 46-55 dan <46 tahun dengan hasil tes menunjukkan adanya hubungan antara usia dengan BPH dengan nilai (p= 0,000), ada hubungan antara obesitas dengan nilai BPH (p=0,019) dan riwayat diabetes mellitus setelah menggunakan uji Chi-Square, hubungan antara riwayat diabetes mellitus dengan BPH dengan nilai (p = 0,000). Kesimpulan. Ada hubungan antara umur, obesitas dan riwayat diabetes mellitus dengan kejadian BPH.

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