Determination of Synergistic Inhibitory Activity of some Nanoparticles and Antibiotic Against Pathogenic Bacteria Caused Acne

AbstractClinical observations show that patients with anorexia nervosa (AN) are surprisingly free from infectious diseases. There is evidence from studies in Drosophila melanogaster that starvation leads to an increased expression of antimicrobial peptides (AMPs). AMPs are part of the innate immune system and protect human surfaces from colonization with pathogenic bacteria, viruses and fungi. We compared the expression of AMPs between patients with AN and healthy controls (HC) and investigated the influence of weight gain. Using a standardized skin rinsing method, quantitative determination of the AMPs psoriasin and RNase 7 was carried out by ELISA. Even though non-significant, effect sizes revealed slightly higher AMP concentrations in HC. After a mean weight gain of 2.0 body mass index points, the concentration of psoriasin on the forehead of patients with AN increased significantly. We could not confirm our hypotheses of higher AMP concentrations in patients with AN that decrease after weight gain. On the contrary, weight gain seems to be associated with increasing AMP concentrations.

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Determination of lethal concentration and antibacterial activity of commonly used disinfectants

International Journal of Natural Sciences ◽

10.3329/ijns.v1i4.9738 ◽

1970 ◽

Vol 1 (4) ◽

pp. 102-105 ◽

Cited By ~ 1

Author(s):

M Alam ◽

MM Rahman ◽

MJ Foysal ◽

MN Hossain

Keyword(s):

Methylene Blue ◽

Pseudomonas Fluorescens ◽

Potassium Permanganate ◽

Malachite Green ◽

Copper Sulfate ◽

Pathogenic Bacteria ◽

Labeo Rohita ◽

Inhibitory Effect ◽

Lethal Concentration

The toxic effects of four disinfectants viz., copper sulfate (CuSO4), potassium permanganate (KMnO4), methylene blue and malachite green on fish and fish pathogenic bacteria Aeromonas sp., Pseudomonas fluorescens, Edwardsiella sp. and Flavobacterium sp. were investigated. Lethal concentration of the disinfectants to fingerlings of Labeo rohita was determined in aquarium by standard method. Lethal concentration of copper sulfate (CuSO4), potassium permanganate (KMnO4), methylene blue and malachite green against fish were found in 0.75ppm, 7ppm, 6ppm and 0.5ppm at 21.4hrs, 18hrs, 9.5hrs and 1.40hrs, respectively. Methylene blue at 4ppm and 5ppm concentration inhibited the growth of Pseudomonas fluorescens and 6ppm concentration suppressed the growth of Aeromonas sp. Copper sulfate (CuSO4) was effective only against Edwardsiella sp at concentration of 10ppm and 8ppm. Malachite green repressed the growth of all four tasted bacteria at a concentration of 1ppm. Potassium permanganate (KMnO4) was failed to exhibit any inhibitory effect on the bacteria even at 30ppm concentration. DOI: http://dx.doi.org/10.3329/ijns.v1i4.9738 IJNS 2011 1(4): 102-105

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The inhibitory activity of Lactobacillus spp. isolated from breast milk on gastrointestinal pathogenic bacteria of nosocomial origin

Anaerobe ◽

10.1016/j.anaerobe.2011.07.008 ◽

2011 ◽

Vol 17 (6) ◽

pp. 474-477 ◽

Cited By ~ 23

Author(s):

Solange Jara ◽

Magaly Sánchez ◽

Rodrigo Vera ◽

Jaime Cofré ◽

Erica Castro

Keyword(s):

Breast Milk ◽

Inhibitory Activity ◽

Pathogenic Bacteria ◽

Lactobacillus Spp

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Determination of the inhibitory activity and biological half-live of soluble CD83: Comparison of wild type and mutant isoforms

Immunobiology ◽

10.1016/j.imbio.2006.05.009 ◽

2006 ◽

Vol 211 (6-8) ◽

pp. 449-453 ◽

Cited By ~ 11

Author(s):

Elisabeth Zinser ◽

Matthias Lechmann ◽

Antje Golka ◽

Barry Hock ◽

Alexander Steinkasserer

Keyword(s):

Inhibitory Activity ◽

Wild Type ◽

Soluble Cd83

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Prevalence of Tonsillitis caused by Streptococcus spp. Among children and the effect of some Lactic acid bacterial (LAB) strain on it

Baghdad Science Journal ◽

10.21123/bsj.13.2.218-227 ◽

2016 ◽

Vol 13 (2) ◽

pp. 218-227

Author(s):

Baghdad Science Journal

Keyword(s):

Inhibitory Activity ◽

Pathogenic Bacteria ◽

Biochemical Characterization ◽

Bacterial Isolate ◽

Inhibition Zone ◽

Laboratory Culture ◽

Diffusion Method ◽

Inhibition Activity ◽

Str System

In this study 100 samples were collected from infected children with acute and chronic tonsillitis who attended to Al-Yarmook Teaching Hospital (ENT consultation clinic) from 5/12/2013 to 1/3/2014. The result of laboratory culture was positive in 67 samples. Depending on their cultural, morphological and biochemical characterization of bacterial isolate of them were identified as (37.31%) belonged to Streptococcus pyogenes and the diagnosis is confirmed by the use of Remel Rapid STR System, (34.32%) belonged to S.parasanguinis, (11.94%) S.mitis, (11.94%) S.oralis and (4.47%) S.thoraltensis . Results confirmed that cup assay gave highest inhibition zone after 24 hrs compare with well diffusion methods for suspension of L.acidophilus gave highest inhibition zone after 48 hrs for incubation, while ahigh inhibition zone revealed for suspension of L.fermentum after 24 hrs incubation. the study included also the measurement of the inhibition activity for bacteriocins produced by L.acidophilus bacteria against pathogenic bacteria on nutrient agar by well diffusion method in which results revealed stability of the bacteriocins produced towards PH which kept its activity with PH 4-6 for 24 hrs, and the highest stability was with PH 4, however it lost a lot of its activity with acidic PH less than 2 and alkaline PH as 8. The treatment of bacteriocins with salts such as Nacl it revealed little effect in inhibition zone within 1 & 2% concetrations. The salt MgSo4 & Kcl showed reduction in the inhibitory activity in the low concentration, however the higher concentration of salt caused great reduction and 5% concentration led to loss of inhibitory activity for bacteriocins completely.

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