scholarly journals Differential reinforcement of low rates : a systematic review

2021 ◽  
Author(s):  
◽  
Alan Lowe
Keyword(s):  
Systematic Review ◽  
Functional Analysis ◽  
Challenging Behavior ◽  
Differential Reinforcement ◽  
Response Rates ◽  
Systematic Search ◽  
Search Process ◽  
Target Behaviors ◽  
Analysis Design

Differential reinforcement of low rates (DRL) is a differential reinforcement variation used to reduce response rates of but not extinguish, a behavior. This review summarizes the applied literature on DRL variations used with children. Reviewed studies included DRL procedures that targeted on challenging behavior. Experimenters identified 21 studies through a systematic search process and evaluated several characteristics of each study including children treated, participants, DRL variations, target behaviors, functional analysis, design, number of sessions, settings, and percentage of improvement. Discussion includes prominent findings, implication and recommendations for future.

scholarly journals Systematic searches

2020 ◽  
Vol 12 (2) ◽  
pp. 55-62
Author(s):  
Magnus Rom Jensen ◽  
Solvor Solhaug
Keyword(s):  
Systematic Review ◽  
Academic Library ◽  
Research Process ◽  
Review Article ◽  
Systematic Search ◽  
Search Process ◽  
Service Needs ◽  
Close Collaboration ◽  
Library Staff

Recent years have seen increasing opportunities for libraries to participate in the research process of our patrons. Our skills in conducting thorough searches and documenting the search process in a transparent way, are highly sought after among researchers looking to write a systematic review article. We give an overview of how this service can be provided in an academic library setting, emphasizing the need for close collaboration between library staff and researchers. We discuss the advantages and limitations of the tools we use, with the aim that others interested in systematic searches can get workable advice. With the increase in information available, researchers need help finding, sorting, screening and documenting the systematic search process. As research librarians we are uniquely positioned to participate in this process. Libraries looking to start offering this service needs to invest in their staff, affording them time to acquire the skill set as well as the time needed for the work involved in the systematic search projects.

A Systematic Review of Trial-Based Functional Analysis of Challenging Behavior

2013 ◽  
Vol 26 (3) ◽  
pp. 271-283 ◽  
Author(s):  
Mandy Rispoli ◽  
Jennifer Ninci ◽  
Leslie Neely ◽  
Samar Zaini
Keyword(s):  
Systematic Review ◽  
Functional Analysis ◽  
Challenging Behavior

Using a Functional Analysis Followed by Differential Reinforcement and Extinction to Reduce Challenging Behaviors in Children With Smith-Magenis Syndrome

2018 ◽  
Vol 123 (6) ◽  
pp. 558-573 ◽  
Author(s):  
Jennifer Hodnett ◽  
Mindy Scheithauer ◽  
Nathan A. Call ◽  
Joanna Lomas Mevers ◽  
Sarah J. Miller
Keyword(s):  
Functional Analysis ◽  
Retinoic Acid ◽  
Behavior Analysis ◽  
Applied Behavior Analysis ◽  
Challenging Behavior ◽  
Differential Reinforcement ◽  
Developmental Delays ◽  
Genetic Disorder ◽  
Challenging Behaviors ◽  
17P11.2 Deletion

Abstract Smith-Magenis syndrome (SMS) is a genetic disorder, commonly caused by a 17p11.2 deletion, affecting the Retinoic Acid Induced 1 gene. It affects approximately 1 in 25,000 individuals, with over 90% engaging in challenging behaviors. Function-based treatments, using the principles of applied behavior analysis, have consistently been shown to decrease challenging behaviors exhibited by individuals with developmental delays. However, additional research is needed to determine the effects of these interventions with specific diagnostic subsets, including SMS. The current study identified the function of challenging behavior for 2 children with SMS and found a function-based treatment, consisting of differential reinforcement and extinction, reduced challenging behavior for both.

scholarly journals CGRP-antibodies, topiramate and botulinum toxin type A in episodic and chronic migraine: A systematic review and meta-analysis

Cephalalgia ◽  
2021 ◽  
pp. 033310242110181
Author(s):  
Florian Frank ◽  
Hanno Ulmer ◽  
Victoria Sidoroff ◽  
Gregor Broessner
Keyword(s):  
Systematic Review ◽  
Monoclonal Antibodies ◽  
Botulinum Toxin ◽  
Response Rate ◽  
Meta Analysis ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Response Rates ◽  
Botulinum Toxin Type ◽  
Odds Ratios

Background The approval of monoclonal antibodies for prevention of migraine has revolutionized treatment for patients. Oral preventatives are still considered first line treatments as head-to-head trials comparing them with antibodies are lacking. Methods The main purpose of this study was to provide a comparative overview of the efficacy of three commonly prescribed migraine preventative medication classes. For this systematic review and meta-analysis, we searched the databases CENTRAL, EMBASE, and MEDLINE until 20 March 2020. We included RCTs reporting the 50% response rates for topiramate, Botulinum Toxin Type A and monoclonal antibodies against CGRP(r). Studies were excluded if response rates were not reported, treatment allocation was unclear, or if study quality was insufficient. Primary outcome measure were the 50% response rates. The pooled odds ratios with 95% confidence intervals were calculated with the random effects model. The study was registered at PROSPERO (CRD42020222880). Findings We identified 6552 reports. Thirty-two were eligible for our review. Studies assessing monoclonal antibodies included 13,302 patients and yielded pooled odds ratios for the 50% response rate of 2.30 (CI: 2.11–2.50). Topiramate had an overall effect estimate of 2.70 (CI: 1.97–3.69) with 1989 included patients and Botulinum Toxin Type A achieved 1.28 (CI: 0.98–1. 67) with 2472 patients included. Interpretation Topiramate, botulinum toxin type A and monoclonal antibodies showed higher odds ratios in achieving a 50% response rate compared to placebo. Topiramate numerically demonstrated the greatest effect size but also the highest drop-out rate.

scholarly journals Neonatal Uterine Bleedings: An Ignored Sign but a Possible Cause of Early-Onset Endometriosis – A Systematic Review

2021 ◽  
pp. 6-16
Author(s):  
Judith  Dekker ◽  
Isabelle Hooijer ◽  
Johannes C.F. Ket ◽  
Aleksandra Vejnović ◽  
Giuseppe Benagiano ◽  
...  
Keyword(s):  
Systematic Review ◽  
Full Text ◽  
Early Onset ◽  
Cochrane Collaboration ◽  
Systematic Search ◽  
Future Research ◽  
Screening Techniques ◽  
Screening Strategies ◽  
The Cochrane Collaboration ◽  
Possible Cause

<b><i>Objective:</i></b> Based on the hypothesis that neonatal uterine bleedings (NUB), occurring mostly in the first week after birth, could represent a pathogenetic mechanism for early-onset endometriosis, this systematic review (SR) was undertaken to evaluate the prevalence and screening strategies used to assess and quantify NUB. <b><i>Design:</i></b> Both a SR and a sample literature search in PubMed and Embase were conducted to gather information on NUB prevalence and screening techniques. This was performed by an information specialist. Only full-text articles regarding the assessment of NUB in neonates in the first 2 weeks after birth were included. No limit on language or publication data was used. <b><i>Materials and Methods:</i></b> The SR was registered in PROSPERO (CRD42019138121). Data was first assessed for eligibility on title and abstract by 2 blinded review authors. Any disagreements were discussed with a third reviewer if necessary. Subsequently, full-text articles were read and assessed for quality using the Cochrane Collaboration Handbook. <b><i>Results:</i></b> Out of 1,988 articles in the systematic search, 10 relevant articles were selected, of which 8 were identified through the systematic search and 2 were found through other sources. The sample search of 4,445 articles did not bring up relevant articles. Results were not comparable due to the heterogeneity of screening techniques, although data showed consensus. The prevalence of visible bleeding ranged from 3.3 to 53.8% and the prevalence of occult bleeding from 25.4 to 96.7%. The occurrence was the highest between the 3rd and 7th day postpartum (PP) and the bleeding lasted for 3–4 days on average. Various screening techniques for detecting NUB were found in the literature, including the use of hemoglobin detection devices (such as Hemastix) in the vaginal vestibulum, comparison of diapers with stains of known volume, colposcopy, and ultrasonography. <b><i>Conclusion:</i></b> The reported prevalence of NUB varies considerably, with a consistent occurrence between the 3rd and the 7th day PP. Literature to assess NUB is dated. The techniques are poorly described and heterogeneous. Future research should focus on prospective cohort studies in order to attempt to correlate NUB cases to (early-onset) endometriosis.

scholarly journals A Critical Review on Mathematical Descriptions to Study Flux Processes and Environmental-Related Interactions of Mangroves

2021 ◽  
Vol 13 (12) ◽  
pp. 6970
Author(s):  
Jefferson Brooks ◽  
Miguel Chen Chen Austin ◽  
Dafni Mora ◽  
Nathalia Tejedor-Flores
Keyword(s):  
Systematic Review ◽  
Mathematical Model ◽  
Global Warming ◽  
Process Modeling ◽  
Critical Review ◽  
Systematic Search ◽  
Raw Material ◽  
Mangrove Forests ◽  
Recent Information ◽  
Modeling Studies

Trees are resources that provide multiple benefits, such as the conservation of fauna, both terrestrial and marine, a source of food and raw material, and offering protection in storms, which makes it practical to understand their behavior against different phenomena. Such understanding may be possible through process modeling. Studies confirm that mangrove forests can store more carbon than other forests, influencing the fight against global warming. Thus, a critical and systematic review was carried out regarding studies focusing on mangroves to collect information on the models that have been applied and the most influential variables highlighted by other authors. Applying a systematic search for the most relevant topics related to mangroves (basic as well as recent information), it is possible to group models and methods carried out by other authors to respond to certain behaviors presented by mangroves. Moreover, possible structuring of a mathematical model applied to a species of interest thanks to the analyzed references could provide justified information to the authorities on the importance of these forests and the benefits of their preservation and regeneration-recovery.

scholarly journals Steroidomics for the Prevention, Assessment, and Management of Cancers: A Systematic Review and Functional Analysis

Metabolites ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 199 ◽  
Author(s):  
Nguyen Hoang Anh ◽  
Nguyen Phuoc Long ◽  
Sun Jo Kim ◽  
Jung Eun Min ◽  
Sang Jun Yoon ◽  
...  
Keyword(s):  
Systematic Review ◽  
Functional Analysis ◽  
Therapy Monitoring ◽  
Small Sample ◽  
Estrogen Metabolism ◽  
Pathway Enrichment Analysis ◽  
Estrogen Metabolites ◽  
High Throughput Analysis ◽  
Cross Sectional ◽  
Analytical Technique

Steroidomics, an analytical technique for steroid biomarker mining, has received much attention in recent years. This systematic review and functional analysis, following the PRISMA statement, aims to provide a comprehensive review and an appraisal of the developments and fundamental issues in steroid high-throughput analysis, with a focus on cancer research. We also discuss potential pitfalls and proposed recommendations for steroidomics-based clinical research. Forty-five studies met our inclusion criteria, with a focus on 12 types of cancer. Most studies focused on cancer risk prediction, followed by diagnosis, prognosis, and therapy monitoring. Prostate cancer was the most frequently studied cancer. Estradiol, dehydroepiandrosterone, and cortisol were mostly reported and altered in at least four types of cancer. Estrogen and estrogen metabolites were highly reported to associate with women-related cancers. Pathway enrichment analysis revealed that steroidogenesis; androgen and estrogen metabolism; and androstenedione metabolism were significantly altered in cancers. Our findings indicated that estradiol, dehydroepiandrosterone, cortisol, and estrogen metabolites, among others, could be considered oncosteroids. Despite noble achievements, significant shortcomings among the investigated studies were small sample sizes, cross-sectional designs, potential confounding factors, and problematic statistical approaches. More efforts are required to establish standardized procedures regarding study design, analytical procedures, and statistical inference.

scholarly journals Placebo response rates in antidepressant trials: a systematic review of published and unpublished double-blind randomised controlled studies

2016 ◽  
Vol 3 (11) ◽  
pp. 1059-1066 ◽  
Author(s):  
Toshi A Furukawa ◽  
Andrea Cipriani ◽  
Lauren Z Atkinson ◽  
Stefan Leucht ◽  
Yusuke Ogawa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Placebo Response ◽  
Response Rates ◽  
Double Blind ◽  
Randomised Controlled

scholarly journals Incidence and Mortality of Anastomotic Dehiscence Requiring Reoperation After Rectal Carcinoma Resection

2014 ◽  
Vol 99 (2) ◽  
pp. 112-119 ◽  
Author(s):  
Zhi-jie Cong ◽  
Liang-hao Hu ◽  
Jun-jie Xing ◽  
Zheng-qian Bian ◽  
Chuan-gang Fu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Rectal Carcinoma ◽  
Anterior Resection ◽  
Rectal Resection ◽  
Postoperative Mortality ◽  
Anastomotic Dehiscence ◽  
Systematic Search ◽  
Anterior Rectal Resection ◽  
Incidence And Mortality ◽  
Definition Of

Abstract Anastomotic dehiscence (AD) requiring reoperation is the most severe complication following anterior rectal resection. We performed a systematic review on studies that describe AD requiring reoperation and its subsequent mortality after anterior resection for rectal carcinoma. A systematic search was performed on published literature. Data on the definition and rate of AD, the number of ADs requiring reoperation, the mortality caused by AD, and the overall postoperative mortality were pooled and analyzed. A total of 39 studies with 24,232 patients were analyzed. The studies varied in incidence and definition of AD. Systematic review of the data showed that the overall rate of AD was 8.6%, and the rate of AD requiring reoperation was 5.4%. The postoperative mortality caused by AD was 0.4%, and the overall postoperative mortality was 1.3%. We found considerable risk and mortality for AD requiring reoperation, which largely contributed to the overall postoperative mortality.

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