scholarly journals CHEMICAL CONSTITUENTS OF THE ROOT OF STREPTOCAULON JUVENTAS MERR.

2011 ◽  
Vol 14 (2) ◽  
pp. 28-35
Author(s):  
Hao Xuan Bui ◽  
Duc Minh Nguyen ◽  
Quan Le Tran
Keyword(s):  
Methanol Extract ◽  
Chemical Constituents ◽  
Spectroscopic Methods ◽  
First Time

From the methanol extract of the root of Streptocaulon juventas Merr, three cardenolide derivatives were isolated. Their strutures were determined by spectroscopic methods. This is the first time that (17α)-H-periplogenin-3-O-β-D-glucopyranosyl-(1–4)-2-O-acetyl-3-O-methyl-β- fucopyranoside (1) and periplogenin-3-O-β-cymaropyranosyl-(1®4)--glucopyranoside (2) were isolated from the root of S. juventas together with the known 17α-H-periplogenin-3-O-β- digitoxopyranosyl-(1®4)-O-β-glucopyranosyl-(1®6)-O-β-glucopyranoside (3).

scholarly journals CONTRIBUTE TO STUDY ON CHEMICAL CONSTITUENTS OF URENA LOBATA (L.) OF VIETNAM

2019 ◽  
Vol 57 (2) ◽  
pp. 162
Author(s):  
Quan Minh Pham ◽  
Hoai Van Thi Tran ◽  
Lam Tien Do ◽  
Phuong Lan Doan ◽  
Inh Thi Cam ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Ethyl Acetate ◽  
Ethyl Acetate Extract ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Spectroscopic Methods ◽  
Tree Roots ◽  
Chemical Structures ◽  
Phytochemical Investigation ◽  
First Time

Urena lobata L. is used in Vietnamese traditional medicine for the treatment of several diseases. Tree roots are used to treat rheumatism, dysentery, poor digestion, flu, tonsils, malaria, asthma, goiter. Flowers are used to treat chickenpox, fever, and mental disorders. Branches, leaves or whole trees used to treat injuries bruises, rheumatism, mastitis, bites. Phytochemical investigation of the n-hexan and ethyl acetate extract of Urena lobata L. led to the isolation of β-sitosterol (1), β-sitosterol-3-O-β-D-glucopyranoside (2), a-acetylamino-phenylpropyl a-benzoylamino-phenylpropanoate (3), quercetin (4), and trans-tiliroside (5). Their chemical structures were determined by spectroscopic methods including MS, 1D, 2D NMR and comparing with those reported in previous papers. Two compounds 3, 5 were isolated for the first time from Urena lobata plant.

(–)-Agelasidine A from Agelas clathrodes

2006 ◽  
Vol 61 (7-8) ◽  
pp. 472-476 ◽  
Author(s):  
Maria Augusta Medeiros ◽  
Ana Lourenço ◽  
Maria Regina Tavares ◽  
Maria João Marcelo Curto ◽  
Sónia Savluchinske Feio ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Marine Sponge ◽  
Methanol Extract ◽  
Spectroscopic Methods ◽  
Antifungal Activities ◽  
Antibacterial And Antifungal Activities ◽  
Bacteriostatic Agent ◽  
Antibacterial And Antifungal ◽  
First Time

(-)-Agelasidine A was identified from the methanol extract of the marine sponge Agelas clathrodes for the first time together with zooanemonin, 1-carboxymethylnicotinic acid, hymenidin, mukanadins A and C, monobromodispacamide, agelasidine D, 2-amide-4-bromopyrrole, O-methyltryptophan and an agelasines mixture. The structures were characterized by spectroscopic methods. (-)-Agelasidine A was tested for antibacterial and antifungal activities and shown to act as a bacteriostatic agent as it inhibited the growth of Staphylococcus aureus and partially the growth of other bacteria.

scholarly journals Triterpenoids and Sterols from the Stem of Alnus Formosana Burk

2006 ◽  
Vol 1 (4) ◽  
pp. 1934578X0600100 ◽  
Author(s):  
Chien-Kuang Chen ◽  
Shiou-Ling Tuh ◽  
Chung-Hsiung Chen ◽  
Chen-Meng Kuo ◽  
Shoei-Sheng Lee
Keyword(s):  
Natural Products ◽  
Betulinic Acid ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
First Time ◽  
Soluble Fractions

The chemical constituents of the stem of Alnus formosana Burk. were investigated and sixteen known compounds, composed of eleven triterpenoids and five sterols, were isolated and characterized from the n-hexane- and chloroform-soluble fractions of the methanol extract. Of these, seven triterpenoids, lupeol, lupenone, betulinic acid, 3-O-acetylbetulinic acid, 3-O-acetylerythrodiol, 3-O-acetyloleanolic aldehyde, and taraxerone, were isolated for the first time from an Alnus species. The isolation of the five sterols, stigmastanone, stigmast-4-en-3-one, β-sitosterol, β-sitosteryl-β-D-glucoside, and stigmasta-3,6-dione, is also the first time that the presence of such natural products has been recorded for an Alnus species. Taraxerone and betulinic acid were the major non-polar constituents of the stem of A. formosana.

Chemical Constituents from Euphorbia helioscopia

2011 ◽  
Vol 396-398 ◽  
pp. 1337-1340 ◽  
Author(s):  
Di Geng ◽  
Lian Jin Weng ◽  
Yuan Yuan Han ◽  
Xin Yang
Keyword(s):  
Silica Gel ◽  
Chemical Constituents ◽  
2D Nmr ◽  
Spectroscopic Methods ◽  
Nmr Spectrum ◽  
Euphorbia Helioscopia ◽  
First Time ◽  
Spectrum Data

AIM: To study the chemical constituents of Euphorbia helioscopia. METHODS: Compounds 1-10 were isolated and purified by silica gel, Sephadex LH-20 and Rp-18 chromatogarphy. Their structures were elucidated mainly by spectroscopic methods. RESULTS: Ten known compounds, helioscopinolide A(1), helioscopinolide B(2), scopoletin(3), scoparone(4), isoscopoletin(5), licochalone A(6), quercelin(7), 7, 4’-dihydroxy-5-methoxy flacanone(8), 2’, 4’-dihydroxy-6’-methoxydihydrochalcone(9) and pinocembrin(10), were isolated and structurally elucidated. CONCLUSION: Compound 3-5 and 8-10 were isolated from this plant for the first time. 2D NMR spectrum data of 2 were also reported in this paper.

scholarly journals Chemical Constituents and Protection of Biodiversity of Corypha taliera Roxb., a Critically Endangered Plant of Bangladesh

2018 ◽  
Vol 20 (2) ◽  
pp. 213-220
Author(s):  
Akhtaruzzaman Chowdhury ◽  
Md Ashraful Alam ◽  
Md Shafiullah Shajib ◽  
Mohammad Abdullah Al Mansur ◽  
Mohammad A Rashid
Keyword(s):  
Spectroscopic Analysis ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Pharmaceutical Journal ◽  
Critically Endangered ◽  
Ex Situ ◽  
Endangered Plant ◽  
Separation And Purification ◽  
First Time ◽  
Mature Seeds

This article focuses on the chemical constituents and protection of biodiversity through plantation of saplings of Corypha taliera Roxb., a critically endangered plant of Bangladesh. Until 2010, the tree in the campus of University of Dhaka, used to be considered as the lone surviving species in the world in nature. Succesive chromatographic separation and purification of the methanol extract of air dried flowers of C. taliera provided β-sitosterol (1), β-amyrin (2), and betulinic acid (3) for the first time from its flowers. The structures of these purified compounds were established by extensive spectroscopic analysis and comparison of spectral data with published values as well as co-TLC with authentic samples. On the other hand, 500 mature seeds were sown in seed beds in the Medicinal Plant Garden of Faculty of Pharmacy, University of Dhaka, and Azimpur Government Officers' Quarter premises. After 40 days, the root was first seen to grow in its habitat and 85 days later the shoot developed up to 2.5 cm in height. The rate of germination was found to be 89-93%. The produced saplings were later on planted in different places of Bangladesh for conservation of the plant and protection of biodiversity by ex situ arrangement.Bangladesh Pharmaceutical Journal 20(2): 213-220, 2017

scholarly journals STUDY ON CHEMICAL CONSTITUENTS AND CYTOTOXICITY OF ASPIDISTRA LETREAE

2020 ◽  
Vol 129 (1B) ◽  
Author(s):  
Duc Viet Ho
Keyword(s):  
Methanol Extract ◽  
Human Cancer ◽  
Chemical Constituents ◽  
Hep G2 ◽  
Pure Compound ◽  
Human Cancer Cell Lines ◽  
Phytochemical Investigation ◽  
Reported Data ◽  
First Time

A phytochemical investigation of whole <em>Aspidistra letreae</em> plants led to the isolation of 2<em>H</em>-chromen-2-one (<strong>1</strong>), <em>α</em>-tocopherol (<strong>2</strong>), (<em>E</em>)-phytol (<strong>3</strong>), asparenydiol (<strong>4</strong>) and (25<em>S</em>)-spirost-1<em>β</em>,3<em>α</em>,5<em>β</em>-triol (<strong>5</strong>). Their structures were determined on the basis of NMR spectral evidences and in comparison with the reported data. Of these, asparenydiol (<strong>4</strong>) was isolated from the genus <em>Aspidistra</em> for the first time. This is also the first report on the separation and structural determination of (25<em>S</em>)-spirost-1<em>β</em>,3<em>α</em>,5<em>β</em>-triol (<strong>5</strong>) as a pure compound. The methanol extract exhibited a moderate cytotoxicity against the LU-1, HeLa, MDA-MB-231, Hep-G2, and MKN-7 human cancer cell lines with <em>IC</em><sub>50</sub> values ranging from 52.58 ± 3.65 to 64.78 ± 4.89 μg/mL.

scholarly journals Chemical Constituents of Blumea balsamifera of Indonesia and Their Protein Tyrosine Phosphatase 1B Inhibitory Activity

2012 ◽  
Vol 7 (7) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Azis Saifudin ◽  
Ken Tanaka ◽  
Shigetoshi Kadota ◽  
Yasuhiro Tezuka
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Inhibitory Activity ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Tyrosine Phosphatase ◽  
Spectroscopic Methods ◽  
Protein Tyrosine Phosphatase 1B ◽  
Dependent Manner ◽  
Protein Tyrosine ◽  
Dose Dependent

A methanol extract of the leaves of Blumea balsamifera (L.) DC. (Asteraceae) afforded a new guaian-type sesquiterpene, epiblumeaene K (1), together with four known guaian-type sesquiterpenes (2–5), three known sesquiterpenes (6–8), and nine known flavonoids (9–17) by a combination of chromatography and preparative TLC techniques. Their structures were elucidated by extensive spectroscopic methods and comparison with the literature data. Among the isolated compounds, a known sesquiterpene, β-caryophyllene 8 R,9 R-oxide (6), exhibited a significant PTP1B inhibitory activity in a dose-dependent manner, with an IC50 value of 25.8μM (5.62μg/mL).

scholarly journals Chemical constituents isolated from the whole plant of Solanum procumbens

2019 ◽  
Vol 2 (6) ◽  
pp. 134-138
Author(s):  
Nguyen Xuan Hai ◽  
Nguyen Trung Nhan ◽  
Nguyen Thi Thanh Mai
Keyword(s):  
Salicylic Acid ◽  
Medicinal Plant ◽  
Benzoic Acid ◽  
Ethyl Acetate Extract ◽  
Chemical Constituents ◽  
Spectroscopic Methods ◽  
Chemical Structures ◽  
Whole Plant ◽  
Solanaceae Family ◽  
First Time

Solanum procumbens L. is a medicinal plant belonging to the Solanaceae family. In Vietnam, it is known as "Ca gai leo", and it cultivated in some tropical countries in China, Laos, Cambodia, and Vietnam. From the stem of the ethyl acetate extract of Solanum procumbens, we had isolated one anthraquinone (1), four polyphenols (2-5), and one indole (6). By spectroscopic methods as well as comparing with data in the literature, their chemical structures were elucidated as ziganein (1), benzoic acid (2), salicylic acid (3), 4-hydroxybenzaldehyde (4), vanillic acid (5), and indole-3-carbaldehyde (6). These compounds were isolated for the first time from the genus Solanum.

Study on Chemical Constituents of Lagotis yunnanensis

2012 ◽  
Vol 554-556 ◽  
pp. 1845-1848 ◽  
Author(s):  
Jin Yang ◽  
Hai Yan Wu ◽  
Qing Hua Li ◽  
Ping Yi ◽  
Yong Min ◽  
...  
Keyword(s):  
Methyl Ether ◽  
Chromatographic Method ◽  
Chemical Constituents ◽  
Ethanol Extract ◽  
Spectroscopic Methods ◽  
Effective Components ◽  
Whole Plant ◽  
First Time

Lagotis yunnanensis is a folkloric medicine in China. In order to investigate its effective components, The 95% ethanol extract of whole plant of L. yunnanensis was separated and purified with chromatographic method. Eight compounds were obtained and identified as luteolin (1), chrysoeriol (2), apigenin-7-methyl ether (3), 3, 4-dimethoxycinnamyl-D-glucopyranoside (4), verbascoside (5), cistanoside D (6), 2-O--D-glucopyranospylcucurbitacin D (7) and arvenin I (8) by spectroscopic methods. Compounds 1~3 are flavonoids, compounds 4~6 are phenylpropanoids and compounds 7 and 8 are triterpenoids. Compounds 4~8 have been obtained from this species for the first time.

CHEMICAL CONSTITUENTS OF ETHYL ACETATE EXTRACT FROM Taxus wallichiana ZUCC. (TAXACEAE) LEAVES COLLECTED IN HA GIANG PROVINCE

2020 ◽  
Vol 65 (6) ◽  
pp. 110-115
Author(s):  
Dien Pham Huu ◽  
My Pham Thi ◽  
Nam Bui Tuan
Keyword(s):  
Ethyl Acetate ◽  
Ethyl Acetate Extract ◽  
Chemical Constituents ◽  
Spectroscopic Methods ◽  
First Time ◽  
Taxus Wallichiana

Investigation on the chemical constituents of ethyl acetate extract from leaves of Taxus wallichiana Zucc. (Taxaceae), collected in Ha Giang province, has resulted in the isolation of three metabolites for the first time: sciadopitysin (1), β-sitosterol (2), and isoquercitrin (3). Their structures were determined by spectroscopic methods.

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