scholarly journals Chemical Constituents and Protection of Biodiversity of Corypha taliera Roxb., a Critically Endangered Plant of Bangladesh

2018 ◽  
Vol 20 (2) ◽  
pp. 213-220
Author(s):  
Akhtaruzzaman Chowdhury ◽  
Md Ashraful Alam ◽  
Md Shafiullah Shajib ◽  
Mohammad Abdullah Al Mansur ◽  
Mohammad A Rashid
Keyword(s):  
Spectroscopic Analysis ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Pharmaceutical Journal ◽  
Critically Endangered ◽  
Ex Situ ◽  
Endangered Plant ◽  
Separation And Purification ◽  
First Time ◽  
Mature Seeds

This article focuses on the chemical constituents and protection of biodiversity through plantation of saplings of Corypha taliera Roxb., a critically endangered plant of Bangladesh. Until 2010, the tree in the campus of University of Dhaka, used to be considered as the lone surviving species in the world in nature. Succesive chromatographic separation and purification of the methanol extract of air dried flowers of C. taliera provided β-sitosterol (1), β-amyrin (2), and betulinic acid (3) for the first time from its flowers. The structures of these purified compounds were established by extensive spectroscopic analysis and comparison of spectral data with published values as well as co-TLC with authentic samples. On the other hand, 500 mature seeds were sown in seed beds in the Medicinal Plant Garden of Faculty of Pharmacy, University of Dhaka, and Azimpur Government Officers' Quarter premises. After 40 days, the root was first seen to grow in its habitat and 85 days later the shoot developed up to 2.5 cm in height. The rate of germination was found to be 89-93%. The produced saplings were later on planted in different places of Bangladesh for conservation of the plant and protection of biodiversity by ex situ arrangement.Bangladesh Pharmaceutical Journal 20(2): 213-220, 2017

scholarly journals Recovery of Globba wengeri (C.E.C. Fisch.) K.J. Williams, critically endangered plant species from Serchhip District in Mizoram, Northeast India

2020 ◽  
Vol 7 (2) ◽  
pp. 178-181
Author(s):  
Lalnun Mawia ◽  
Vanlalhruaii Ralte ◽  
H. Lalruatsanga ◽  
Zothan Mawia ◽  
P.C. Vanlalhluna ◽  
...  
Keyword(s):  
Life History ◽  
Plant Species ◽  
Natural Habitat ◽  
Northeast India ◽  
Critically Endangered ◽  
Endangered Plant ◽  
Endangered Plant Species ◽  
The Family ◽  
First Time

Globba wengeri (C.E.C. Fisch.) K.J. Williams, former state flower of Mizoram, a rare and critically endangered plant species, commonly known as ‘dancing girl’, belonging to the family Zingiberaceae, is reported in this communication for the first time from Serchhip District in Mizoram at an elevation of about 1187 m a.s.l. It was found on moist, watery and rocky slopes. The plant is under severe threat in the natural habitat and therefore, further studies are required to determine life history and particular survival threats of this species.

scholarly journals Chemical constituents of Euphorbia tirucalli L.

2019 ◽  
Vol 2 (5) ◽  
pp. 76-82
Author(s):  
Dung Thi Kim Le ◽  
Hao Xuan Bui ◽  
Tuyet Thi Anh Nguyen ◽  
Tuyen Nguyen Kim Pham ◽  
Huy Thuc Duong
Keyword(s):  
Thin Layer ◽  
Gallic Acid ◽  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
Normal Phase ◽  
Chemical Structures ◽  
Euphorbia Tirucalli ◽  
Arjunolic Acid ◽  
First Time ◽  
Layer Chromatography

Euphorbia tirucalli has not been chemically studied much in Vietnam. This research described the isolation and elucidation of compounds isolated from the plant collected in Binh Thuan. Multiple chromatographic methods were applied, including normal phase silica gel column chromatography and thin-layer chromatography. Seven compounds were isolated and their chemical structures were elucidated by spectroscopic analysis as well as comparing their data with the ones in the literature. They are arjunolic acid (1), eriodictyol (2), quercitrin (3), afzelin (4), scopoletin (5), 3,3′,4- trimethylellagic acid (6), and gallic acid (7). Among them, compound 1 a major component was isolated for the first time in Euphorbia genus, while three compounds 2, 4, and 5 were isolated from this species for the first time.

scholarly journals Triterpenoids and Sterols from the Stem of Alnus Formosana Burk

2006 ◽  
Vol 1 (4) ◽  
pp. 1934578X0600100 ◽  
Author(s):  
Chien-Kuang Chen ◽  
Shiou-Ling Tuh ◽  
Chung-Hsiung Chen ◽  
Chen-Meng Kuo ◽  
Shoei-Sheng Lee
Keyword(s):  
Natural Products ◽  
Betulinic Acid ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
First Time ◽  
Soluble Fractions

The chemical constituents of the stem of Alnus formosana Burk. were investigated and sixteen known compounds, composed of eleven triterpenoids and five sterols, were isolated and characterized from the n-hexane- and chloroform-soluble fractions of the methanol extract. Of these, seven triterpenoids, lupeol, lupenone, betulinic acid, 3-O-acetylbetulinic acid, 3-O-acetylerythrodiol, 3-O-acetyloleanolic aldehyde, and taraxerone, were isolated for the first time from an Alnus species. The isolation of the five sterols, stigmastanone, stigmast-4-en-3-one, β-sitosterol, β-sitosteryl-β-D-glucoside, and stigmasta-3,6-dione, is also the first time that the presence of such natural products has been recorded for an Alnus species. Taraxerone and betulinic acid were the major non-polar constituents of the stem of A. formosana.

Chemical constituents of the stem bark of Acacia AuriculiformisA.Cunn ex. Benth. (fabaceae)

2020 ◽  
Vol 23 ◽  
pp. 88-91
Author(s):  
A.A. Ahmadu ◽  
B.A. Lawal ◽  
B. Olanipekun ◽  
A. Udobre ◽  
N. Tsafantakis ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Secondary Metabolites ◽  
Acid Ester ◽  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
Stem Bark ◽  
Acacia Auriculiformis ◽  
Compound I ◽  
Literature Report ◽  
First Time

The genus Acacia has been known to be a rich source of many secondary metabolites. This study was carried to isolate chemical constituents present in the stem bark of Acacia auriculiformis. The dichloromethane extract of the stem bark of Acacia auriculiformis was obtained by maceration. The extract obtained was subjected to silica gel column chromatography and preparative TLC. The isolated compounds were identified by spectroscopic analysis. This led to the isolation of ferulic acid ester (I), along with a steroid (II) and a triterpenoid (III). The structure of compound I was established using spectroscopic analysis (UV, IR, NMR and mass spectrometry) and identified to be dodecyl-4-hydroxy-3-methoxy-trans-cinnamate (I), compounds II and III were found to be á-spinasterol and lupenol respectively, based on the comparison of their spectral data NMR and MS with literature report. Compound I is being reported for the first time in the genus Acacia.

scholarly journals CHEMICAL CONSTITUENTS OF THE ROOT OF STREPTOCAULON JUVENTAS MERR.

2011 ◽  
Vol 14 (2) ◽  
pp. 28-35
Author(s):  
Hao Xuan Bui ◽  
Duc Minh Nguyen ◽  
Quan Le Tran
Keyword(s):  
Methanol Extract ◽  
Chemical Constituents ◽  
Spectroscopic Methods ◽  
First Time

From the methanol extract of the root of Streptocaulon juventas Merr, three cardenolide derivatives were isolated. Their strutures were determined by spectroscopic methods. This is the first time that (17α)-H-periplogenin-3-O-β-D-glucopyranosyl-(1–4)-2-O-acetyl-3-O-methyl-β- fucopyranoside (1) and periplogenin-3-O-β-cymaropyranosyl-(1®4)--glucopyranoside (2) were isolated from the root of S. juventas together with the known 17α-H-periplogenin-3-O-β- digitoxopyranosyl-(1®4)-O-β-glucopyranosyl-(1®6)-O-β-glucopyranoside (3).

scholarly journals STUDY ON CHEMICAL CONSTITUENTS AND CYTOTOXICITY OF ASPIDISTRA LETREAE

2020 ◽  
Vol 129 (1B) ◽  
Author(s):  
Duc Viet Ho
Keyword(s):  
Methanol Extract ◽  
Human Cancer ◽  
Chemical Constituents ◽  
Hep G2 ◽  
Pure Compound ◽  
Human Cancer Cell Lines ◽  
Phytochemical Investigation ◽  
Reported Data ◽  
First Time

A phytochemical investigation of whole <em>Aspidistra letreae</em> plants led to the isolation of 2<em>H</em>-chromen-2-one (<strong>1</strong>), <em>α</em>-tocopherol (<strong>2</strong>), (<em>E</em>)-phytol (<strong>3</strong>), asparenydiol (<strong>4</strong>) and (25<em>S</em>)-spirost-1<em>β</em>,3<em>α</em>,5<em>β</em>-triol (<strong>5</strong>). Their structures were determined on the basis of NMR spectral evidences and in comparison with the reported data. Of these, asparenydiol (<strong>4</strong>) was isolated from the genus <em>Aspidistra</em> for the first time. This is also the first report on the separation and structural determination of (25<em>S</em>)-spirost-1<em>β</em>,3<em>α</em>,5<em>β</em>-triol (<strong>5</strong>) as a pure compound. The methanol extract exhibited a moderate cytotoxicity against the LU-1, HeLa, MDA-MB-231, Hep-G2, and MKN-7 human cancer cell lines with <em>IC</em><sub>50</sub> values ranging from 52.58 ± 3.65 to 64.78 ± 4.89 μg/mL.

scholarly journals Chemical constituents of the lichen Roccella sinensis growing in Binh Thuan province

2019 ◽  
Vol 2 (5) ◽  
pp. 63-67
Author(s):  
Huy Thuc Duong ◽  
Hao Xuan Bui
Keyword(s):  
Spectroscopic Analysis ◽  
Chemical Constituents ◽  
Human Lung Cancer ◽  
Cytotoxic Activities ◽  
Human Breast ◽  
Nmr Data ◽  
Liver Hepatocellular Carcinoma ◽  
First Time ◽  
Layer Chromatography ◽  
Mcf 7

The lichen Roccella sinensis has not been studied chemically. This research described the isolation and elucidation of compounds isolated from the lichen Roccella sinensis collected in Binh Thuan. Phytochemistry investigation of this lichen was carried out by using normal phase silica gel column chromatography and thin-layer chromatography. Six compounds was isolated. Their structures were established by extensively spectroscopic analysis as well as comparison with NMR data in the literatures. They are (+)-D-montagnetol (1), (+)-D-erythrin (2), lecanorin (3), 1-acetylerythritol (4), (E)-nostodione A (5), and 2,4-dihydroxyphthalide (6). This is the first time compounds 3 6 were found in the Roccella genus. Compounds 1, 2, and 6 were evaluated for their cytotoxic activities against HepG2 (liver hepatocellular carcinoma), NCI-H460 (human lung cancer), MCF-7 (human breast cancer), and HeLa (human epithelial cancer) and all of them showed no activity.

scholarly journals Chemical constituents and theira-glucosidase inhibitory activity of the stem of Salacia chinensis L.

2021 ◽  
Vol 5 (3) ◽  
pp. first
Author(s):  
Huu Tho Le ◽  
Truc Thanh Thi Duong ◽  
Phu Hoang Dang ◽  
Truong Nhat Van Do ◽  
Hai Xuan Nguyen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Back Pain ◽  
Inhibitory Activity ◽  
Spectroscopic Analysis ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Positive Control ◽  
Ic50 Values ◽  
Treatment Of Diabetes ◽  
Chcl3 Fraction

Salacia chinensis L., known as “Chop mao” in Vietnam, is a climbing shrub that belongs to the Celastraceae family. The stem of S. chinensis L. is used as a traditional medicine for the treatment of diabetes, rheumatoid arthritis, back pain, … The dried powdered stem of S. chinensis L. was collected in Phu Yen province and was extracted with methanol to yield methanol extract. The methanol extract was suspended in H2O and partitioned successively with n-hexane, CHCl3, EtOAc to obtain n-hexane, CHCl3, EtOAc, and H2O fractions, respectively. The CHCl3 fraction was subjected to a series of chromatographic separation to afford four purified compounds including 3-oxolup-20(29)-en-30-al (1), betulin-3-caffeate (2), 2-(4-hydroxy-3,5-dimethoxylphenyl)ethanol (3), and acetosyringone (4). Their structures were elucidated on the basis of the spectroscopic analysis and comparison with literature data. The isolated compounds were tested for their α-glucosidase inhibitory activity. The result indicated that all compounds (1-4) possessed significant α-glucosidase at the testing concentration of 100 µM with the percent inhibition values of 9.5 ± 1.3, 70.89 ± 0.25, 44.2 ± 1.6, and 6.7 ± 1.7 %, respectively. In addition, betulin-3-caffeate (2) and 2-(4-hydroxy-3,5-dimethoxylphenyl)ethanol (3) show more potent α-glucosidase inhibitory activity, with IC50 values of 69.7 and 152.0 µM, respectively, than that of positive control acarbose (IC50 = 214.5 µM).

scholarly journals Bioactive Metabolites from the Deep-Sea-Derived Fungus Diaporthe longicolla FS429

Marine Drugs ◽  
2020 ◽  
Vol 18 (8) ◽  
pp. 381
Author(s):  
Zhaoming Liu ◽  
Yuchan Chen ◽  
Saini Li ◽  
Qinglin Wang ◽  
Caiyun Hu ◽  
...  
Keyword(s):  
Deep Sea ◽  
Spectroscopic Analysis ◽  
Methanol Extract ◽  
Tyrosine Phosphatase ◽  
Bioactive Metabolites ◽  
X Ray Diffraction ◽  
Antiproliferative Effects ◽  
X Ray ◽  
Ic50 Value ◽  
First Time

The chemical investigation of a methanol extract of the deep-sea-derived fungus Diaporthe longicolla FS429 led to the isolation of two novel diterpenoids longidiacids A and B (1 and 2), two new polyketides (3 and 4), two new cytochalasin analogues longichalasins A and B (6 and 8) and three known analogues 5, 7, 9. Their structures were elucidated through comprehensive spectroscopic analysis, while the absolute configurations were established by the comparison of the experimental and quantum chemical calculated ECD spectra. The structure of compound 7 was confirmed through X-ray diffraction for the first time. In the bioassays compound 8 exhibited antiproliferative effects against SF-268, with an IC50 value of 16.44 μM. Moreover, compounds 1 and 8 were detected to inhibit 35.4% and 53.5% of enzyme activity of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) at a concentration of 50 μM.

scholarly journals Sterol and triterpenoids from Hygrophila schulli Buch.-Ham.

2018 ◽  
Vol 44 (2) ◽  
pp. 319-321
Author(s):  
Md Abu Suflan ◽  
Fatema Begum ◽  
Mohammad Rashedul Haque ◽  
Choudhury Mamood Hasan ◽  
Mohammad Abdur Rashid
Keyword(s):  
1H Nmr ◽  
Chromatographic Separation ◽  
Methanol Extract ◽  
Chemical Constituents ◽  
Published Data ◽  
Separation And Purification ◽  
First Report ◽  
Spectral Evidence ◽  
Whole Plants

The methanol extract of whole plants of Hygrophila schulli Buch.-Ham. was subjected to repeated chromatographic separation and purification processes to isolate its chemical constituents. A total of three compounds were isolated which have been characterized as stigmasterol, lupeol and lup-20(29)-ene-3β,23- diol on the basis of 1H NMR spectral evidence and confirmed by comparing with published data, as well as co-TLC in case of stigmasterol and lupeol. This is the first report of lup-20(29)-ene-3β,23-diol from this plant.

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