scholarly journals Pengaruh suplementasi probiotik Lactobacillus casei L shirota strain terhadap kadar IgE penderita rinitis alergi

2011 ◽  
Vol 41 (1) ◽  
pp. 60
Author(s):  
Asti Widuri ◽  
Lilis Suryani
Keyword(s):  
Allergic Rhinitis ◽  
Lactobacillus Casei ◽  
Immunoglobulin E ◽  
T Test ◽  
Mucosal Barrier ◽  
Inflammatory Reactions ◽  
Lactobacillus Casei Shirota ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Paired T Test

Background: Allergic rhinitis is a nasal mucosal inflammatory reactions mediated by immunoglobulin E (IgE), after allergen exposure. Probiotics is considered has strong influence on the regulation of primary immunophysiology in intestinal mucosal barrier and might be useful to prevent allergy attacks.Purpose: To study the benefits of Lactobacillus casei Shirota strain L in preventing allergy attacks through the mechanism  of immunomodulatory systems that inhibit the production of IgE. Methods:The study was quasi-experimental  with pretest-posttest design. The subjects were 45 students with history of allergic rhinitis. Serum IgE levels were measured before and after given milk containing probiotics for one month. Results: With a paired t test, there was significant difference of the average IgE levels between before (291.88 IU/L) and after one month. Probiotic supplementation (141.43 IU/L),p<0.05. Conclusion: Supplementation of probiotic Lactobacillus casei Shirota strain L is useful in preventing allergy attacks.  Keywords: allergic rhinitis, probiotics, immunoglobulin E (IgE) Abstrak :  Latar belakang: Rinitis alergi adalah reaksi peradangan mukosa hidung yang diperantarai oleh imunoglobulin E (IgE) setelah terjadi pajanan alergen. Pemberian probiotik dianggap mempunyai pengaruh yang kuat terhadap regulasi imunofisiologi primer dalam barier mukosa usus. Tujuan:Mengkaji manfaat suplemen probiotik Lactobacillus casei L shirota strain dalam mencegah serangan alergi melalui mekanisme sistem imunomodulator yang menghambat produksi IgE. Metode: Desain penelitian adalah eksperimental kuasi case control dengan rancangan pretest-postest design. Subjek penelitian adalah 45 orang yang mempunyai riwayat rinitis alergi, diambil darah sampel untuk diperiksa kadar IgE sebelum dan setelah diberi susu yang mengandung probiotik selama satu bulan. Hasil: Dengan paired t test, terdapat perbedaan bermakna antara rata-rata kadar IgE sebelum suplementasi (291,88 IU/L) dan setelah diberi suplementasi probiotik Lactobacillus casei Lshirota strain selama satu bulan (141,43 IU/L), p<0,05. Kesimpulan: Suplementasi probiotikLactobacillus casei L shirota strain bermanfaat dalam mencegah serangan alergi melalui mekanisme imunomodulator yang menghambat produksi IgE. Kata kunci: rinitis alergi, probiotik, imunogobulin E (IgE)

The Effects of Probiotic Lactobacillus casei Shirota Strain in Patients with Allergic Rhinitis Symptoms

2015 ◽  
Vol 4 (4) ◽  
pp. 264
Author(s):  
Asti Widuri ◽  
Lilis Suryani
Keyword(s):  
Allergic Rhinitis ◽  
Lactobacillus Casei ◽  
Immunoglobulin E ◽  
Nasal Congestion ◽  
Rank Test ◽  
Inflammatory Reactions ◽  
Runny Nose ◽  
Before And After ◽  
Quasi Experimental ◽  
Signed Rank Test

Allergic rhinitis is inflammatory reactions mediated by immunoglobulin E, after exposure to allergens. The symptoms are sneezing, runny nose and nasal congestion. Allergic rhinitis can be alleviated by the use of specific probiotics selected to confer immune effects, which can be demonstrated in the intestinal tract prior to an allergic reaction. The specific strains used in this study were selected based on their anti-inflammatory properties and an expected effect in promoting a Th1 type of immune response. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. The study design was quasi-experimental with pre and post test design. The subject were 45 patients who had a history of allergic rhinitis and positif skin prickt test result and filled out the questionnaires to get the allergic symptoms. The blood samples were taken for examining the IgE and IL-4 levels then after giving milk containing probiotics for 1 month, the researcher did the same examination. The mean IgE and IL-4 levels decrease before and after supplementation probiotics from 291.88 IU / L and 22.48 pg/ml to 141.43 IU / L and 17.83 pg/ml. The result of the statistical analysis paired t-test test was p = 0.00 on IgE level and p=0,056 on IL-4 level. The allergic rhinitis symptoms decreased significantly, the presentage of patients who had persistent and moderate 17.78% to 0% , who had persistent and mild 44.44% to 4.44%, who had intermittent and moderate 13.33% to 2.22%,and who had intermittent and mild 24.44% to 93.33%. Based on the Wilcoxon signed rank test showed a significance value of P = 0.00. Conclusion Probiotics is useful in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms.

scholarly journals The Effects of Probiotic Lactobacillus casei Shirota Strain in Patients with Allergic Rhinitis Symptoms

2015 ◽  
Vol 4 (4) ◽  
pp. 264
Author(s):  
Asti Widuri ◽  
Lilis Suryani
Keyword(s):  
Allergic Rhinitis ◽  
Lactobacillus Casei ◽  
Immunoglobulin E ◽  
Nasal Congestion ◽  
Rank Test ◽  
Inflammatory Reactions ◽  
Runny Nose ◽  
Before And After ◽  
Quasi Experimental ◽  
Signed Rank Test

Allergic rhinitis is inflammatory reactions mediated by immunoglobulin E, after exposure to allergens. The symptoms are sneezing, runny nose and nasal congestion. Allergic rhinitis can be alleviated by the use of specific probiotics selected to confer immune effects, which can be demonstrated in the intestinal tract prior to an allergic reaction. The specific strains used in this study were selected based on their anti-inflammatory properties and an expected effect in promoting a Th1 type of immune response. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. The study design was quasi-experimental with pre and post test design. The subject were 45 patients who had a history of allergic rhinitis and positif skin prickt test result and filled out the questionnaires to get the allergic symptoms. The blood samples were taken for examining the IgE and IL-4 levels then after giving milk containing probiotics for 1 month, the researcher did the same examination. The mean IgE and IL-4 levels decrease before and after supplementation probiotics from 291.88 IU / L and 22.48 pg/ml to 141.43 IU / L and 17.83 pg/ml. The result of the statistical analysis paired t-test test was p = 0.00 on IgE level and p=0,056 on IL-4 level. The allergic rhinitis symptoms decreased significantly, the presentage of patients who had persistent and moderate 17.78% to 0% , who had persistent and mild 44.44% to 4.44%, who had intermittent and moderate 13.33% to 2.22%,and who had intermittent and mild 24.44% to 93.33%. Based on the Wilcoxon signed rank test showed a significance value of P = 0.00. Conclusion Probiotics is useful in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms.

scholarly journals PERBEDAAN PH SALIVA ANTARA BERKUMUR DAN TANPA BERKUMUR AIR PUTIH SETELAH MENGUNYAH MAKANAN BERKARBOHIDRAT SEDERHANA

2016 ◽  
Vol 4 (1) ◽  
pp. 67-77
Author(s):  
Miftahul Jannah ◽  
Hidayati Hidayati ◽  
Afriwardi Afriwardi
Keyword(s):  
Drinking Water ◽  
T Test ◽  
Significant Difference ◽  
Salivary Ph ◽  
Post Test ◽  
Quasi Experimental ◽  
The Difference ◽  
Simple Carbohydrates ◽  
Paired T Test ◽  
Simple Carbohydrate

The Difference Of Salivary pH Between Rinsing and without Rinsing with Drinking Water After Chewing Simple Carbohydrate. Salivary pH is one of indicator in oral health. One factor that influences salivary pH is diet. Diet simple carbohydrates decrease salivary pH. Rinsing with drinking water suspected that can increase salivary pH. to know how the difference of salivary pH between rinsing and without rinsing with drinking water after chewing simple carbohydrates. Quasi experimental used with pre test and post test design on 40 students as samples. The measurement of salivary pH was done by digital pH meter “Pen Type pH tester”. The test which was used was paired T-test. The result Showed that Salivary pH the rinsing group after chewing was 6.96 ± 0.52 and 7.02 ±0,50 without rinsing. Salivary pH after rinsing minutes to 5 was 6.94 ± 0.52 and 6.79 ±0.52 without rinse. The pH of saliva rinsing the 20th minute was 7.12 ± 0.49 and 6.89 ± 0.50 without rinsing. The results of Paired t-test showed the significant difference from the salivary pH to 5th minute after rinsing and without rinsing with chewing simple carbohydrate foods with p <0.05 (p = 0.009) but, there was no significant difference of salivary pH in the 20th minute and 5 minutes after rinsing and without rinsing  with p> 0.05 (p = 0.140). rinsing by using drinking water can increase the salivary pH after chewing simple carbohydrate foods. Keywords: Rinsing drinking water, Simple Carbohydrates, Salivary pH

scholarly journals Effects of Inquiry- Based Learning Approach on Learning Achievement and Learning Satisfaction among Grade Four Students towards Science

2021 ◽  
pp. 25-32
Author(s):  
Sonam Tshering ◽  
Pema Yangden
Keyword(s):  
Random Sampling ◽  
Achievement Test ◽  
T Test ◽  
Learning Approach ◽  
Learning Achievement ◽  
Inquiry Based Learning ◽  
Learning Satisfaction ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Paired T Test

The purpose of this study was to examine the effects of Inquiry based learning approach on learning achievement and learning satisfaction among grade 4 students in science. The study used a quasi-experimental design. A clustered random sampling was used to select 2 sections out of 3 sections of grade four students. The research instruments implemented were achievement test, questionnaire and observation form were used to collect the data. The experiment was carried out for 5 consecutive weeks. The statistics used for data analysis were mean, standard deviation, paired and independent t-test. The analysis of the result on learning achievement showed that there was a significant difference between the means of pretest and posttest and paired t-test also gave the significant value of p=0.00 (<0.05). Similarly, the overall mean of the student learning satisfaction was 4.61 which indicated that students were extremely satisfied with inquiry based learning approach. The results of the data showed that the Inquiry-based learning approach was effective in achieving high scores and as well the learning satisfaction of the students in science.

scholarly journals Pengaruh Pemberian Madu Terhadap Berat Badan Dan Kadar Malondialdehyd Pada Ibu Hamil Dengan Anemia

2021 ◽  
Vol 6 (3) ◽  
Author(s):  
Astuti Astuti ◽  
Kartika Asli ◽  
Asrida Asrida ◽  
Nunung Erviany ◽  
Ummul Khair
Keyword(s):  
Pregnant Women ◽  
Intervention Group ◽  
T Test ◽  
Control Group ◽  
P Value ◽  
Design Data ◽  
Average Value ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Paired T Test

Honey contains complex nutrients including vitamins A, C, E, B and flavonoids which play a role in suppressing oxidative stress. This study aimed to determine the effect of honey and Fe on body weight and malondialdehyde (MDA) levels of anemia pregnant women. The type of this study was quasi-experimental with the pretest-posttest design. Data analysis using paired t-test and independent samples test. After implementation the average value of the intervention group was 2.30 ± 0.50 while the average value of the control group was 2.00 ± 0.20 which showed that there was an effect of giving honey + Fe and Fe to the weight of anemic pregnant women. Whereas the statistical test results of the independent samples test showed p> 0.05 (p = 0.307) which means that there was no significant difference between the administration of honey + Fe (intervention) and Fe (control). In the melondialdehyde (MDA) variable there was a decrease in the intervention group by 8.86 ± 2.78 with the paired t-test obtained p value 0.002, this indicates there is an effect of giving honey + Fe to malondialdehyde (MDA) levels. The average value in the control group was 0.92 ± 0.07 with the paired t-test p value of 0.653 indicating no effect of Fe on Melondialdehyde (MDA) levels. Based on the test of the independent samples test obtained p value 0.004 (α <0.05). Conclusion: administration of honey + Fe effectively reduces malondialdehyde (MDA) levels and increases the weight of anemic pregnant women.

scholarly journals Pengaruh Musik Terhadap Respirasi Bayi Berat Lahir Rendah Selama Kangaroo Mother Care Di RSUD Aloei Saboe Kota Gorontalo

2019 ◽  
Vol 14 (2) ◽  
pp. 87-94
Author(s):  
Nancy Olii
Keyword(s):  
Classical Music ◽  
District Hospital ◽  
Positive Influence ◽  
T Test ◽  
P Value ◽  
Music Intervention ◽  
Organ Systems ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Paired T Test

Every year in the world an estimated 20 million babies are born with low birth weight, a burden on social and community health in developing countries. LBW has difficulty in adapting to extra-uterine life due to the immaturity of the body's organ systems such as the lungs, heart, kidneys, liver, and digestive system. Efforts to increase respiration in LBW need to be given management pharmacologically and non-pharmacologically in the form of music. The purpose of this study was to determine the effect of music on LBW infant respiration during KMC in Aloei Saboe District Hospital, Gorontalo City. This type of research uses a quasi-experimental method, a sample of 30 people. Data were analyzed by Univariate and Bivariate by Paired T-test. Results: Based on statistical calculations using paired t-test obtained p value = 0,000 where sig <0.05, so that Ho was rejected and Ha was accepted, meaning that there was a significant difference between before classical music intervention and after classical music intervention on BBRR infant respiration during KMC at Aloei Saboe District Hospital. Conclusion: There is a positive influence between classical music on LBW respiration during KMC at Aloei Saboe Regional Hospital, Gorontalo City. Suggestion: Classical music can be played to optimize LBW care during KMC at the NICU and as an alternative in improving physiological responses, especially respiration in LBW infants.

scholarly journals INTERVENSI KADER DALAM MENDUKUNG PROGRAM PEMBERIAN OBAT MASSAL PENCEGAHAN (POMP) FILARIASIS DI KECAMATAN CIBEUREUM DAN CIBINGBIN, KABUPATEN KUNINGAN, PROVINSI JAWA BARAT

2018 ◽  
Vol 17 (1) ◽  
pp. 31-40
Author(s):  
Joni Hendri ◽  
Mara Ipa ◽  
Aryo Ginanjar ◽  
Yuneu Yuliasih ◽  
Endang Puji Astuti
Keyword(s):  
T Test ◽  
Control Group ◽  
P Value ◽  
Attitude And Practice ◽  
Significant Difference ◽  
Post Test ◽  
Quasi Experimental ◽  
The Difference ◽  
Knowledge Attitude And Practice ◽  
Paired T Test

ABSTRACT The filariasis mass drug administration (MDA) program is one of the strategies to eliminate lymphatic filariasis. First round coverage in Kuningan Regency was 85.4%, but only 50% of sub-districts have reached the target. The aim of this research was to determine the improvement of knowledge, attitude, and practice (KAP) of health cadres through intervention to increase the filariasis MDA coverage in Kuningan Regency. A quasi-experimental research was conducted in Cibeureum and Cibingbin Sub-District of Kuningan Regency using pretest-posttest design from May to October 2016. Selected subjects of this research were 32 health cadres who were given intervention in the form of workshop utilizing leaflets, handbooks, and video. The difference is treatment group was taught about filariasis related materials by an expert but the control group was not. Data were analyzed with paired t-test. The result showed that there was a significant difference between pre-test and post-test in terms of KAP in both groups with p-value of 0,000, but there was no difference in value between the two groups. Thus, the study concluded that training on cadres with a filariasis expert could be an effective strategy as to increase MDA coverage. Keywords: Intervention, filariasis MDA, knowledge, cadre   ABSTRAK Pemberian Obat Massal Pencegahan (POMP) merupakan salah satu strategi eliminasi filariasis di Indonesia. Hasil cakupan POMP putaran pertama di Kabupaten Kuningan mencapai 85,4% dari total target penduduk, namun hanya 50% kecamatan yang mencapainya. Tujuan penelitian ini adalah untuk mengetahui peningkatan pengetahuan, sikap dan perilaku kader setelah dilakukan intervensi dalam rangka meningkatkan cakupan pengobatan filariasis di Kabupaten Kuningan. Penelitian dilakukan di Kecamatan Cibeureum dan Cibingbin, Kabupaten Kuningan pada bulan Mei - Oktober tahun 2016 dengan eksperimen semu menggunakan desain  pretest-posttest control group. Sampel penelitian adalah 32 kader yang diberi intervensi berupa pelatihan dengan media cetak  dan video. Perbedaan antara kelompok intervensi dengan kontrol adalah bahwa kelompok intervensi diajarkan materi terkait filariasis oleh seorang ahli dan kelompok kontrol tidak diberikan pelatihan. Data dianalisis menggunakan paired t-test. Hasil penelitian menunjukkan adanya perbedaan pada skor nilai pretest-posttest pengetahuan, sikap, dan perilaku pada masing-masing kedua kelompok dengan hubungan bermakna (p-value 0,000), tetapi tidak terdapat perbedaan nilai pretest-posttest antara kelompok intervensi dan kontrol. Hal ini berarti tidak ada perbedaan yang signifikan antara kelompok intervensi dan kontrol. Kesimpulannya bahwa pelatihan pada kader menggunakan media cetak dan video dengan narasumber pakar filariasis merupakan salah satu strategi efektif untuk meningkatkan cakupan pengobatan POMP filariasis. Kata kunci: Intervensi, POMP, pengetahuan, kader

scholarly journals ONLINE BRAINSTORMING LEARNING TECHNIQUE INCREASES INNOVATION IN STUDENTS’UNDERSTANDING AND CREATIVITY

2020 ◽  
Vol 5 (36) ◽  
pp. 114-120
Author(s):  
Sitti Junaida Ambo ◽  
Tan Choon Keong
Keyword(s):  
Online Learning ◽  
Quantitative Study ◽  
Creative Thinking ◽  
T Test ◽  
Significant Difference ◽  
Learning Technique ◽  
Post Test ◽  
Quasi Experimental ◽  
The Subject ◽  
Paired T Test

This research aimed to study students’ understanding and creative thinking in Innovation Subject through online learning. This quasi-experimental quantitative study focussed on students’ understanding and creative thinking of the subject through online learning brainstorming techniques. Samples of 36 students from School Y went through the treatment (online learning) and all of the students sat for the pre-test and post-test to measure their understanding and creativity of the subject. Results from paired t-test have shown that there is a significant difference between creativity and understanding of the subject in pre-test and post-test. This showed that online learning has successfully increased students understanding and creative thinking of the subject, aligned with the government’s wish and education blueprint, which is to produce outstanding citizens.

scholarly journals THE EFFECT OF SUPPLEMENTATION PROBIOTIC Lactobacillus casei STRAIN Shirota L AGAINST COLONIZATION OF Staphylococcus aureus Nasal Swab ISOLATES FROM PATIENTS WITH ALLERGIC RHINITIS

2015 ◽  
Vol 2 (1) ◽  
pp. 124
Author(s):  
Lilis Suryani
Keyword(s):  
Staphylococcus Aureus ◽  
Allergic Rhinitis ◽  
Lactobacillus Casei ◽  
Nasal Swab ◽  
Intestinal Flora ◽  
Control Group ◽  
School Of Medicine ◽  
Lactobacillus Casei Shirota ◽  
Probiotic Lactobacillus ◽  
Quasi Experimental

<p>Staphylococcus aureus is the most important type of bacteria causing infections in humans. There are several potential factors for Staphylococcus aureus nasal careers in healthy adults, i.e. chronic sinusitis, the long-term skin trauma, respiratory allergies, asthma, allergen injection therapy. Probiotics are life microorganisms which have a positive effect on prevention or treatment of certain disease conditions when consumed. Manipulation of intestinal flora with probiotics for the prevention and treatment of rhinitis allergy should be developed. This study aims to determine the effect of supplementation probiotic Lactobacillus casei Shirota strain against colonization Staphylococcus aureus nasal swab isolates from patients with allergic rhinitis. <br />This research was quasi-experimental case-control design with a control group pretest-postest design. The study was conducted at the Microbiology and Research Laboratory School of Medicine Muhammadiyah Yogyakarta University, on February-July 2011. Fourty two students school of medicine Muhammadiyah Yogyakarta University, with the inclusion criteria suspect allergic rhinitis based on history. Volunteers who have a history of allergic rhinitis were taken nasal swab to check the number of S.aureus bacteria. Volunters consumed milk containing Lactobacillus casei strain Shirota daily for a month, then taken to be examined nasal swab S.aureus bacteria numbers. <br />The results showed that the average number of bacteria nasal swab isolates before supplementation about 92 CFU. After given the probiotic Lactobacillus casei Shirota strain during a month, the average number of S.aureus about 27 CFU. It can be concluded that supplementation with Lactobacillus casei strain Shirota probiotics can reduce Staphylococcus aureus colonization in patients with allergic rhinitis.</p><p><br /><strong>Keywords</strong>: Staphylococcus aureus, Lactobacillus casei, allergic rhinitis</p>

scholarly journals PERBEDAAN PH SALIVA ANTARA BERKUMUR DAN TANPA BERKUMUR AIR PUTIH SETELAH MENGUNYAH MAKANAN BERKARBOHIDRAT SEDERHANA

2018 ◽  
Vol 6 (1) ◽  
pp. 62-68
Author(s):  
Miftahul Jannah ◽  
Hidayati Hidayati ◽  
Afriwardi Afriwardi
Keyword(s):  
Drinking Water ◽  
T Test ◽  
Significant Difference ◽  
Salivary Ph ◽  
Post Test ◽  
Quasi Experimental ◽  
The Difference ◽  
Simple Carbohydrates ◽  
Paired T Test ◽  
Simple Carbohydrate

The Difference Of Salivary pH Between Rinsing and without Rinsing with Drinking Water After Chewing Simple Carbohydrate. Salivary pH is one of indicator in oral health. One factor that influences salivary pH is diet. Diet simple carbohydrates decrease salivary pH. Rinsing with drinking water suspected that can increase salivary pH. to know how the difference of salivary pH between rinsing and without rinsing with drinking water after chewing simple carbohydrates. Quasi experimental used with pre test and post test design on 40 students as samples. The measurement of salivary pH was done by digital pH meter “Pen Type pH tester”. The test which was used was paired T-test. The result Showed that Salivary pH the rinsing group after chewing was 6.96 ± 0.52 and 7.02 ±0,50 without rinsing. Salivary pH after rinsing minutes to 5 was 6.94 ± 0.52 and 6.79 ±0.52 without rinse. The pH of saliva rinsing the 20th minute was 7.12 ± 0.49 and 6.89 ± 0.50 without rinsing. The results of Paired t-test showed the significant difference from the salivary pH to 5th minute after rinsing and without rinsing with chewing simple carbohydrate foods with p <0.05 (p = 0.009) but, there was no significant difference of salivary pH in the 20th minute and 5 minutes after rinsing and without rinsing  with p> 0.05 (p = 0.140). rinsing by using drinking water can increase the salivary pH after chewing simple carbohydrate foods. Keywords: Rinsing drinking water, Simple Carbohydrates, Salivary pH

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