scholarly journals STI Co-infection Among HIV/AIDS Patients at H. Adam Malik General Hospital, Medan, Indonesia

2020 ◽  
Vol 2 (2) ◽  
pp. 63-70
Author(s):  
Safirah Khairuna
Keyword(s):  
General Hospital ◽  
Clinical Stage ◽  
Common Type ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Parallel Port ◽  
Aids Patients ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Hiv Aids

Both HIV/AIDS and Sexually Transmitted Infection (STI) are transmitted through sexual activites making a parallel port of entry making the two condition  increase the each other’s transmission which results as an impact to progression of HIV infection. This study aims to determine the characteristics of HIV/AIDS patients co-infected with sexually transmitted infections in H. Adam Malik General Hospital Medan between 2017 and 2018. This study is a descriptive observational study of 2422 HIV/AIDS patients attending H. Adam Malik General Hospital. Of those, 62 patients were diagnosed with STI coinfection. The majority of patients were male (85,5%) aged within the group of 25 – 49 years old (80,6%), had the level education of high school (88,7%), mostly were entrepreneurs (50%), and were single (59,7%). Most of the patients were already in their Stadium III (80,6%) clinical stage and had CD4+ count < 200/mm3 (51,6%). Condyloma acuminatum (35,5%) was found as the most common type of STI coinfection, and followed by Hepatitis B (33,9%).Based on anamnesis history, behavioral risk factors (66,1%) was the most frequent risk    factor

The Epidemiological Analysis of HIV/AIDS Patients: Sexually Transmitted Diseases Department VS. Other Departments in A General Hospital of Shanghai, China

2021 ◽  
Vol 19 ◽  
Author(s):  
Yue Yu ◽  
Liangliang Shen ◽  
Yufei Li ◽  
Jingjun Zhao ◽  
Heping Liu
Keyword(s):  
Sexually Transmitted Diseases ◽  
General Hospital ◽  
Demographic Characteristics ◽  
Hiv Screening ◽  
Aids Patients ◽  
Important Place ◽  
Sexually Transmitted ◽  
Positive Rate ◽  
Social Demographic ◽  
Hiv Aids

Background: Hospital is an important place for HIV/AIDS screening, and a general hospital is composed of multiple departments. Different departments have different levels of understanding of HIV/AIDS, especially the sexually transmitted diseases (STD) department is the main place for HIV/AIDS screening. Objective: The study aims to validate the common knowledge that the STD department is an important place for HIV/AIDS screening by comparing the epidemiological characteristics of HIV/AIDS patients in the STD department and other departments in Tongji Hospital, which can provide a theoretical basis for the precise and differentiated control of HIV/AIDS. Methods: A total of 283,525 HIV screening cases were analyzed from January 1st 2006 to December 31st 2018 in the STD department and other departments. The epidemiological data of 226 HIV/AIDS cases were retrospectively analyzed. Results : Firstly, the incidence of HIV/AIDS in the population served by Tongji Hospital was higher than that in Shanghai and China. Secondly, the positive rate of HIV screening test in the STD department was ten times higher than that of other departments. Thirdly, the social-demographic characteristics of HIV/AIDS patients in the STD department were different from those in other departments. Fourthly, there were differences in age, education, marital status and number of sex partners between men who have sex with men (MSM) and men who have sex with women (MSW). Fifthly, there was no difference except age in social-demographic characteristics of MSM between the STD department and other departments. Sixthly, compared with other departments, the majority of HIV/AIDS patients in the STD department were MSM. Seventhly, syphilis and HIV co-infection were not statistically significant in HIV/AIDS patients between the STD department and other departments. Conclusion: Firstly, the significantly higher positive rate of an HIV screening test in the STD department emphasizes its importance as a place for screening HIV/AIDS patients. Secondly, HIV/AIDS patients diagnosed in the general hospital were mainly transmitted by sexual contact, and MSM accounted for the most part of these patients. More attention should be paid to screen outpatients, especially in the STD department and young men.

scholarly journals Socio-Behavioral Risk Factors Associated with Cryptosporidiosis in HIV/AIDS Patients Visiting the HIV Referral Clinic at Cape Coast Teaching Hospital, Ghana

2018 ◽  
Vol 12 (1) ◽  
pp. 106-116
Author(s):  
Yeboah K. Opoku ◽  
Johnson N. Boampong ◽  
Irene Ayi ◽  
Godwin Kwakye-Nuako ◽  
Dorcas Obiri-Yeboah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drinking Water ◽  
Risk Factor ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Cape Coast ◽  
Aids Patients ◽  
Factors Associated ◽  
Enteric Protozoan ◽  
Hiv Aids

Objective:To identify the socio-behavioral risk factors associated with cryptosporidiosis among HIV/AIDS patients with chronic diarrhea symptoms visiting the HIV referral clinic at Cape Coast Teaching Hospital, Ghana.Methods:A cross-sectional study was conducted among 50 HIV/AIDS patients with recurrent diarrhea. Questionnaires were administered to collect social and behavioral risk factors associated withCryptosporidiumand other opportunistic protozoan parasitic infections in HIV patients. Stool samples were collected for the diagnosis of enteric protozoan pathogens using modified Ziehl-Neelsen and acid-fast staining methods. CD4+cells counts of study subjects were obtained from patients clinical records. The data obtained were analyzed using Pearson chi-square and multivariate-adjusted statistics tool on SPSS 16 for Windows.Results:Twenty-seven (54%) of the subjects were infected with enteric protozoan pathogens. The prevalences ofCryptosporidium,CyclosporaandMicrosporidiuminfections were 46%, 32% and 16%, respectively.Cryptosporidiuminfection was significantly associated with drinking water (×2=13.528, p<0.001),Cyclosporawas associated with the type of drinking water (×2=14.931, p<0.001) and toilet facilities used by the study subjects (×2=12.463, p<0.01), whilesMicrosporidiuminfection was associated with hand washing behavior (×2=12.463, p<0.01). Enteric protozoans were frequently encountered among subjects with CD4+ T-cell count <200 cells/mm3. However, coinfection ofCyclospora spp&Cryptosporidiumspp was not observed in CD4+cell count <200 and >500 cells/mm3.Multivariate analysis showed that the risk factor forCryptosporidiuminfection among HIV/AIDS patients was the source of drinking water (pipe borne water 76.2% prevalence: sachet water 25%; OR=0.10, 95%CI: 0.03-0.39, p<0.001).Conclusion:We report the risk factor for exposure ofCryptosporidiuminfection among HIV/AIDS patients for the first time in Ghana. The contamination of drinking water by protozoan parasites should be a public health concern. These results provide the stepping block to understand the transmission dynamics ofCryptosporidiumand other opportunistic pathogens in HIV/AIDS infected patients in Ghana.

scholarly journals Risk Factors for Mortality among HIV/AIDS Patients

2021 ◽  
Vol 2 (1) ◽  
pp. 20-19
Author(s):  
Zaki Mita Kusumaadhi ◽  
Nur Farhanah ◽  
Muchlis Achsan Udji Sofro
Keyword(s):  
Risk Factors ◽  
Pulmonary Tuberculosis ◽  
General Hospital ◽  
Clinical Stage ◽  
Significant Risk ◽  
Cd4 Count ◽  
Aids Patients ◽  
Male Sex ◽  
Compliance To Treatment ◽  
Hiv Aids

Background: Morbidity and mortality of HIV/AIDS infections is still high and as  a global health problem particularly in Low-Middle Income Countries (LMICs). Indonesia ranks third in Asia Pacific in increasing HIV infection. A Study on risk factors for mortality in HIV/AIDS patients in Dr. Kariadi General Hospital has never been conducted. This study analyzed the risk factors for mortality among HIV/AIDS patients.Methods: Case control study, data from medical records of inpatients and outpatients in Dr. Kariadi General Hospital from January 2015 to December 2017.Results: Study subject: Two hundred and ten HIV/AIDS patients, were included; 105 (56.75%) as cases and 105 (9.65%) control patients. The significant risk factors for mortality were as follow: male sex (p = 0.030); age ≥ 45 years (p = 0.035); non compliance to treatment (p = 0,000); WHO clinical stage III and IV (p = 0,000); co-infection of pulmonary tuberculosis (p = 0,000); CD4 cell count < 200 cells/mm3 (p = 0,000); eGFR < 60 mL/minute/1.72 m2 (p = 0.001) and Haemoglobin level < 10 g/dL (p = 0.008). The non-significant risk factors for mortality were as follow: level of education (p = 0.650); Hepatitis B co-infection (p = 0.153) and Hepatitis C co-infection (p = 0.506). The most important risk factors for mortality in this study in were non compliance to treatment (p = 0.003; OR = 3.285) and CD4 count < 200 cells/mm3 (p = 0.014; OR = 5.480).Conclusion: In this study, the risk factors for mortality in HIV/AIDS patients were male sex; age ≥ 45 years; non compliance to treatment; WHO clinical stage III and IV; co-infection of pulmonary tuberculosis, CD4 count < 200 cells/mm3; eGFR < 60 mL/minute/1.72 m2 and Hb level < 10 g/dL. The most important risk factors for mortality were non compliance to treatment and CD4 count < 200 cells / mm3.

Factors associated to first line antiretroviral therapy (ART) failure among HIV/AIDS patients at Sanglah Hospital, Bali

2017 ◽  
pp. 4
Author(s):  
Cok Istri Sri Dharma Astiti ◽  
A.A Sagung Sawitri ◽  
Tuti Parwati
Keyword(s):  
Risk Factors ◽  
Treatment Failure ◽  
Clinical Stage ◽  
Hiv And Aids ◽  
First Line ◽  
Aids Patients ◽  
Factors Associated ◽  
Art Initiation ◽  
Risk Of Treatment ◽  
Hiv Aids

Background and purpose: The incidence of first line ART failure is increasing in the South East Asia region. The main referral hospital in Bali has recorded an increased use of second line ART due to the first line ART failure. This study aims to explore risk factors associated to first line ART failure.Methods: A case control study was conducted among people living with HIV and AIDS at Sanglah Hospital Denpasar who started first line ART between 2004 and 2013. Cases were those who diagnosed as having clinical treatment failure and still on treatment in 2015. Controls were those with no treatment failure. Sex and year of ART initiation were matched between case and control. Data were obtained from medical records that include initial regiments, HIV mode of transmission, the WHO HIV clinical stage, CD4 count, opportunistic infections, body mass index, hemoglobin level, and drug substitution at the beginning and during treatment. Risk factors were analysed using logistic regression.Results: Out of 68 HIV/AIDS patients with clinical ART failure, 72.1% were confirmed with immunological and 36.8% were confirmed with virological failure. Median time before treatment failure was 3.5 years. Factors associated to ART failure were HIV clinical stage IV with (AOR=3.43; 95%CI=1.65-7.13) and being widow/widower (AOR=4.85; 95%CI=1.52-15.53). Patients with TB co-infection have a lower risk for treatment failure due to early diagnosis and treatment through TB-HIV program with (AOR=0.32; 95%CI=0.14-0.70).Conclusions: Higher HIV clinical stage at ART initiation increases the risk of treatment failure. HIV-TB co-infection indirectly reduces the risk of treatment failure.

scholarly journals Body mass index increases CD4+ count in HIV/AIDS patients on first-line therapy

2020 ◽  
Vol 39 (2) ◽  
pp. 121
Author(s):  
Mirna Widiyanti ◽  
Moch Irfan Hadi ◽  
Mei Lina Fitri Kumalasari ◽  
Evi Iriani Natalia ◽  
Dedi Ananta Purba ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Antiretroviral Therapy ◽  
Body Mass ◽  
Influencing Factor ◽  
Clinical Stage ◽  
Cd4 Count ◽  
First Line ◽  
Aids Patients ◽  
Cd4 Counts ◽  
Hiv Aids

Background<br />The body mass index (BMI) may contribute somewhat to drug metabolism, thus affecting the efficacy of antiretroviral therapy (ART). CD4+ counts   in people infected with HIV are essential in determining the stage of the disease, initiation of antiretroviral therapy, opportunistic infections and evaluating treatment outcomes. The aim of this study was to determine the association of BMI and clinical stage with CD4+ counts in HIV patients seeking treatment using first-line antiretroviral therapy (ART).<br /><br />Methods<br />An analytic study with a cross-sectional approach was conducted involving 251 HIV/AIDS patients who had received first-line antiretrovirals over six months. BMI, clinical staging according to WHO and CD4 + were collected. Multiple linear regression was used to evaluate the relationship between BMI, clinical stage and CD4+.<br /><br />Results<br />Among the enrolled patients, the median age was 36 years, 135 (55%) of the patients was female, 102 (40.6%) was overweight/obese, 161 (64.1%) was in stage 3 of the disease, and the median CD4+ count was 389 cells/mm3. Multiple linear regression test showed two variables with a significant effect on CD4+ count, namely BMI (B=69.247; 95 % CI : 42.886-95.608) and clinical stage (B=61.590; 28.910-94.270). BMI was the most influencing factor for CD4+ count (β=0.307) compared to clinical stage (β=0.216). <br /><br />Conclusions<br />Body mass index was the most influencing factor for CD4 + counts of HIV/AIDS patients. Regular ART can increase CD4+ counts and maintain the health of HIV/AIDS patients.

Experimental Components Analysis of Brief Theory-Based HIV/AIDS Risk-Reduction Counseling for Sexually Transmitted Infection Patients.

2005 ◽  
Vol 24 (2) ◽  
pp. 198-208 ◽  
Author(s):  
Seth C. Kalichman ◽  
Demetria Cain ◽  
Lance Weinhardt ◽  
Eric Benotsch ◽  
Kelly Presser ◽  
...  
Keyword(s):  
Risk Reduction ◽  
Sexually Transmitted Infection ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Aids Risk ◽  
Components Analysis ◽  
Risk Reduction Counseling ◽  
Hiv Aids

scholarly journals Susceptibility Pattern of Neisseria gonorrhoeae towards Cefixime and Ceftriaxone using Kirby-Bauer Method in Dr. Saiful Anwar General Hospital Malang

2020 ◽  
Vol 32 (2) ◽  
pp. 103
Author(s):  
Lita Setyowatie ◽  
Tantari SHW ◽  
Inneke Yulian
Keyword(s):  
Neisseria Gonorrhoeae ◽  
General Hospital ◽  
Positive Culture ◽  
Test Results ◽  
Susceptibility Pattern ◽  
First Line ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Gram Staining ◽  
Antibiotic Susceptibility Test

Background: Gonorrhea remains the second most common sexually transmitted infection (STI) in the world with an increasing number of cases. Oral cefixime and IM ceftriaxone are still the mainstay therapy for gonorrhea in Indonesia. However, previous studies suggested possible resistance to ceftriaxone and cefixime, which are the first-line treatment of gonorrhea. To date, there are no data available regarding the susceptibility of these antibiotics for the treatment of gonorrhea in Dr. Saiful Anwar General Hospital (RSSA) Malang. Purpose: Determine susceptibility pattern of Neisseria gonorrhoeaetowards cefixime and ceftriaxone in RSSA Malang. Methods: The samples were patients of the Outpatient Clinic of Dermatology and Venereology Department with a symptom of discharge which contained Gram-negative diplococcus after Gram staining and had a positive culture of Neisseria gonorrhoeae. Susceptibility testing for cefixime and ceftriaxone antibiotics were performed using the Kirby-Bauer method. The data are presented in percentages. Result: Antibiotic susceptibility test results showed that 80.77% of Neisseria gonorrhoeaeisolates were still susceptible to cefixime, and 80.77% of isolates were still susceptible to ceftriaxone. Conclusion: Cefixime and ceftriaxone are still effective as gonorrhea therapy in RSSA Malang. 

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