scholarly journals Pediatric resuscitation, emergencies in pediatrics. Various infusion methods for children

2020 ◽  
pp. 97-99
Author(s):  
T. Erler

Background. Medical care for premature babies in Germany is divided into two levels. Perinatal centers of the first level provide care for infants with body weight at birth <1500 g. Perinatal centers of the second level provide care for children whose body weight exceeds 1500 g. In order to be included in the list of first level institutions, the hospital must, among other, be able to pick up children from other institutions in the surrounding region. Mobile incubators are used for this purpose. Such an incubator is a kind of a mobile intensive care unit. In some cases, the incubator is delivered to the desired location by helicopter, but in most cases, specialized road transport is used. Objective. To describe neonatological medical care in Germany. Materials and methods. Analysis of own experience and available literature data on this issue. Results and discussion. In recent years, Germany experiences a decrease in the number of births, which causes the problem of professional training of doctors. Hospitals with the fewest births are closed due to lack of efficiency. Although there are some fluctuations from year to year, in general, the number of premature babies with extremely low birth weight remains approximately constant. Prematurity remains one of the most important problems of modern medicine, as it is accompanied by high mortality rates. The earlier the premature birth is and the lower the body weight is, the higher these rates are. Prematurity is caused by numerous risk factors. Multiple pregnancies are accompanied by the highest risk of premature birth. The presence of twins or triples increases this risk by 7.7 times. Other risk factors include vaginal bleeding in late pregnancy, preeclampsia, and a history of preterm birth. Over the past 20 years, the survival of children born before 32 weeks of pregnancy or weighing <1500 g has increased by almost 20 %. The smallest premature baby born in our clinic is a baby born at 24 weeks of gestation with a body weight of 350 g. Nowadays in Germany, the survival rate of infants born after 24 weeks of gestation is almost 80 %, and after 29 weeks – almost 100 %. It should be noted that maintaining the life of a premature baby from birth to discharge costs 250-300 thousand euros. Bronchopulmonary dysplasia is an important problem of premature infants, especially in case of mechanical lung ventilation (MLV) or joining infections. Up to 40 % of children who die from complications of bronchopulmonary dysplasia can be saved. If possible, MLV and infections should be avoided, premature births should be prevented, so-called neuroprotective ventilation and nasal or mask devices that do not require intubation should be used. Surfactants have made great progress in the management of premature infants. The modern LISA (less invasive surfactant administration) method allows to inject a surfactant into a child’s lungs without intubation. In the early 20th century, 100 % oxygen was used in the resuscitation of newborns, but now we use air (21 % oxygen) or a mixture containing up to 30 % oxygen. To prevent necrotizing enterocolitis, premature infants are prescribed probiotics based on lyophilized lactic acid bacteria and bifidobacteria. Breast milk is an another way to prevent this complication of prematurity. There is a breast milk bank in Potsdam. Conclusions. 1. Prematurity remains one of the most important problems of modern medicine, as it is accompanied by high mortality rates. 2. Multiple pregnancies are accompanied by the highest risk of premature birth. 3. Nowadays in Germany, the survival rate of children born after 24 weeks of gestation is almost 80 %, and after 29 weeks – almost 100 %. 4. Surfactants and the LISA method have made great progress in the management of premature infants. 5. Probiotics and breast milk are prescribed to premature babies to prevent necrotizing enterocolitis.

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Pasqua Anna Quitadamo ◽  
Giuseppina Palumbo ◽  
Liliana Cianti ◽  
Matteo Luigi Napolitano ◽  
Ciro Coviello ◽  
...  

The breast milk is the gold standard food for the feeding of the premature baby: it is the natural way to provide excellent nutritional, immunological, and biological nutriment so as to facilitate a healthy growth and the development of the infants. When the breast milk is not available, the alternative is represented by the donated milk. The mothers of premature infants are important opportunity if we consider the fact that they could devote some milk both because they provide a food which is closer to the needs of the vulnerable category of newborns and because it is, for the mothers, a way to overcome the detachment and the psychological trauma of a premature birth. There are no data on this kind of donation. The aim of the study is to evaluate the contribution of the milk donation to the HMB of CSS by women who gave birth to premature infants of gestational age <35 weeks and to analyze the macronutrient composition of the “preterm” donated milk. The CSS HMB has recruited 659 donors totalling 2236 liters of donated milk over a period of 7 years. 38 donors (5.7%) gave birth to a gestational age <35 weeks. Almost 20% of the donated milk comes from mothers of premature babies and this is a very important fact because it shows the huge potential belonging to this category of mothers. Taking into account the parameter regarding the birth weight, it was found that VLBW mothers contributed for 56% to preterm donation while ELBW mothers contributed for 41%. By evaluating the variable gestational age, about 40% of the average total donation derives from mothers who gave birth before the 25 weeks, while a contribution of 46% is attributable to the category of newborns with a GA between 25 and 32 weeks. Besides, some other exceptional examples can be outlined. Regarding the correlation analysis DM resulted in negative correlation with GA weeks (r=-0.31, p=0.058) and with BW g (r=-0.30, p=0.068) achieving values which are very close to the significance. The comparison between the donor volume averages of the preterm and full-term groups is statistically significant. The composition data are in line with the literature: there is an increase by 18 % in the protein component of the milk deriving from the mothers of the premature infants; the gap in carbohydrates is less significant (5-6%) and the gap in calories is similarly low being only 2% higher than the single donor milk and 11% more than the pooled milk. The data on the lipids line up to single donor term milk, while it grows by 24% compared to the pooled one. The study shows that even at very low or extreme gestational age it is possible to obtain an appropriate production of breast milk. This awareness becomes a fundamental starting point for the activation in a standardized way of all the strategies of promotion and support of food that have proven effective with the HM in NICU.


2019 ◽  
Vol 18 (2) ◽  
pp. 75-82 ◽  
Author(s):  
D. R. Sharafutdinova ◽  
E. N. Balashova ◽  
O. V. Ionov ◽  
A. R. Kirtbaya ◽  
J. M. Golubtsova ◽  
...  

Anemia of prematurity is a common pathology in premature infants. The prevalence of anemia of prematurity is inversely proportional to the gestational age and body weight at birth. The pathogenetic importance of impaired erythropoietin (EPO) production in anemia of prematurity provides the rationale for therapy with erythropoiesis stimulating agents (ESAs) including recombinant EPO. A comparative analysis of the effectiveness of different regimens of recombinant human erythropoietin in extremely and very low birth weight infants (ELBW and VLBW) was studied. Research has been set as a prospective analysis of 133 VLBW and ELBW infants (in the period from December 2017 to February 2019). Gestational age (GA) of the children ranged from 26 to 33 weeks, of these, GA of 75 children (56%) was 30 weeks or less. Depending on the treatment of anemia of prematurity all infants were divided into 5 groups: group 1 (n = 26) – premature babies who were prescribed ESAs since 3 day of life 200 IU/kg 3 times per week subcutaneously; group 2 (n = 21) – premature babies who were prescribed ESAs since 3 day of life 400 IU/kg 3 times per week subcutaneously; group 3 (n = 37) – premature babies who were prescribed ESAs since 8 day of life 200 IU/kg 3 times per week subcutaneously; group 4 (n = 18) – premature babies who were prescribed ESAs since 8 day of life 400 IU/kg 3 times per week subcutaneously; group 5 (n = 31) premature infants who did not receive treatment with recombinant human erythropoietin (control group). Subgroups of children of gestational age ≤ 30 weeks were identified in each group. The groups and subgroups did not differ significantly in gestational age, weight, birth length, and Apgar score at 1 and 5 minutes of life, p > 0.05. Also, there were no statistically significant differences in the age of the 1st transfusion, the frequency and total volume of transfusions, the duration of respiratory therapy, the duration of hospitalization, including treatment in NICU, body weight and age at discharge. The frequency of retinopathy of prematurity stage ≥ 3, periventricular leukomalacia, bronchopulmonary dysplasia of moderate and severe severity, intraventricular hemorrhages of varying severity, necrotizing enterocolitis was not statistically significant in the study groups and subgroups. Statistically significant differences in the concentration of hemoglobin in the peripheral blood of premature infants were revealed at discharge. In the control group, children had a lower level of hemoglobin at discharge (94 g/l) compared with the groups with early appointment of ESAs (109 g/l and 107 g/l in groups 1 and 2, respectively, P0-1 = 0.048 and P0-2 = 0.047) due to newborn GA ≤ 30 weeks. It is preferable to use of the drug ESAs at a dose of 200 IU/kg 3 p/week p/, starting from the 3rd day of life. The effectiveness of erythropoietin therapy, the time of its start and various treatment regimens remain controversial issues that require further study. The study was approved by the Independent Ethics Committee of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov.


2020 ◽  
Vol 13 (4) ◽  
pp. 87-90
Author(s):  
M. V. Zueva ◽  
O. A. Ushnikova ◽  
L. A. Katargina

In recent publications, positive results have been reported with the use of glasses with red protective filters in prematurely born infants with low body weight, which were presumably associated with a decrease in the levels of illumination of the environment of the child. However, to date, it has not been proven that a decrease in the amount of light reaching the retina of the newborn affects the frequency and severity of retinopathy of prematurity (RP). The analysis of the literature on the therapeutic effect of various modes of red and near infrared radiation on the retina is presented, which allowed a different look at the protective mechanisms of glasses-filters in premature babies. It has been suggested and substantiated that the observed effect may relate to the phenomenon of pre-conditioning photostimulation, which reduces the risk of developing RP and reduces the severity of the disease due to the induction of adaptive plastic reactions in the retina.


Author(s):  
Angela Hoyos ◽  
Pablo Vasquez-Hoyos

Introduction: Some of the practices in medicine are carried out of habit without proven benefits. This is the case of premature babies from 31 to 34 weeks of gestation who are always given parenteral fluids, even though this practice has been associated with an increase incidence of infection. In 2017, we started a protocol of parenteral fluid restriction. To administer nutrition/fluids, we used oral fluids by suction if this was possible or otherwise by oral/nasogastric tube at volumes of 15-20 mL intake every 3 hours, with 5 mL increments every 12-24 hours until 200 mL/K/day was achieved, always using breast milk when possible.Material and methods: The present study sought to compare cases before and after this new policy. For this work, we review all premature babies between 31-34 weeks of gestation discharged home in two periods of time, the first from 01/01/2012 to 12/31/2017 and the second from 01/01/2018 to 08/31/2021. The number of cases with and without parenteral fluids (PF), the incidence of infection, the weight at admission and discharge, and the fall in the weight Z score between birth and discharge were compared. Both the anthropometric and outcome variables were compared using the different statistical methods according to each variable.Results: 725 cases were found with the described characteristics. The groups before and after the intervention did not show significant differences in their general demographic characteristics. A lower use of PF was observed in the second period from 348 cases (79%) to 70 (24%), p &lt;0.001 and fewer days of use (4.1 days/case vs 1.3, p &lt;0.0001) of PF. The weight at discharge and the change in weight Z-score were the same in both groups. Infections went from three cases to zero but it was not statistically significant. There were no complications due to less use of PF.Discussion: This study showed that the use of PF is not associated with significant changes in outcomes of interest, which reinforces that its use does not generate any benefit for the patient. Larger number of cases is required to detect differences in low incidence events such as infections.


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Marnie Ch. Ondang ◽  
Eddy Suparman ◽  
Hermie M.M. Tendean

Abstract: According to WHO, about 13 millions babies were born prematurely in this world, and less than 1 million premature babies die every year. Around 14 million teenagers become mothers every year and more than 90% of young mothers were in developing countries. Rate of premature birth around 10-20% in Indonesia in 2009 which causes Indonesia becomes the big 5 of the most premature births. According to Riskesdas in 2013 pregnancy in the age 10-54 years in Indonesia was 2,68% higher in cities than in suburban/villages. From women aged 10-54 there are 0.02% pregnant women under 15 years old. This was a descriptive retrospective, study using medical record data of the patients who had premature labour among teenagers acording to age, education, job, marital status, parity, health, head presentation. The results showed that of 31 cases of premature labours in teenagers, 22 cases or 70.96% of them are delivered by women age 18 to 19-year-old, the last education level they had in average is high school which is 64.51%, the majority of them, 93.54% are working as housewives, 83.87% are married, 25 cases or 80.64% of them are primigravida, the highest factors of premature baby, 12.90 % is the ruptured amnion which happened far before the due date of the baby’s delivery, and 90.32% of the case is baby’s head in facing-down position. Conclusion: Premature labours were mostly found in the age group of 18 to 19-year-old with ruptured of amnion long before the baby’s delivery as the highest complication factor, and utmost cases with the baby’s head is in facing-down position.Keywords: preterm labor, teenagers. Abstrak: Menurut WHO ± 13 juta bayi lahir prematur di dunia, dan >1 juta bayi yang lahir prematur meninggal setiap tahunnya. Sekitar 14 juta anak remaja wanita menjadi ibu setiap tahun dan lebih dari 90% dari para ibu muda berada di negara berkembang. Angka kelahiran prematur berkisar 10-20% di Indonesia pada tahun 2009 yang menyebabkan Indonesia masuk dalam peringkat kelima dengan kelahiran prematur terbesar. Berdasarkan Riskesdas 2013 kehamilan umur 10-54 tahun di Indonesia adalah 2,68%, di perkotaan lebih tinggi dibanding perdesaan. Di antara wanita umur 10-54 tahun terdapat kehamilan umur <15 tahun (0,02%). Jenis penelitian ialah deskriptif retrospektif, menggunakan data rekam medik pasien yang melahirkan prematur pada usia remaja berdasarkan umur, pendidikan, pekerjaan, status perkawinan, paritas, penyakit/penyulit, presentasi kepala. Dari 31 kasus persalinan prematur pada remaja, didapatkan paling sering pada usia 18-19 tahun sebanyak 22 kasus (70,96%), pendidikan terakhir terbanyak SMA (64,51%), pekerjaan terbanyak IRT (93,54%), dengan status menikah (83,87%) dan jumlah primigravida 25 kasus (80,64%). Penyakit/penyulit persalinan terbanyak Ketuban Pecah Dini (12,90%) dengan presentasi letak kepala (90,32%). Simpulan: Persalinan prematur pada remaja paling sering ditemukan pada kelompok usia 18-19 tahun dan penyulit tertinggi yaitu ketuban pecah dini dengan jenis presentasi kepala tinggi. Kata kunci: persalinan prematur, kehamilan remaja.


2019 ◽  
Vol 4 (2) ◽  
pp. 4
Author(s):  
Rosalinna Rosalinna ◽  
Asti Andriyani

Background: Premature infants have a risk of death in the first year of life mainly due to prematurity. Developmental stimulation interventions in premature infants can have a positive impact on weight gain and infant development. The purpose of this study was to determine the effect of the application of growth and development intervention booklets on mothers who had a premature baby to increase the growth and development of infants aged 0-6 months in Karanganyar Regency. Method: The method used in this study is the method in this study. This research uses a quantitative method with a Quasy experiment in the form of a pre-post test design. The sample in this study was Mother and Baby in Karanganyar District who had met the inclusion and exclusion criteria. Results: The results of this study showed that there were differences in body weight and height growth before and after the study in the control group (ρ <0.05). There were no differences in development before and after the study in the control group (ρ> 0.05). There were differences in body weight and height growth before and after the study in the intervention group (ρ <0.05). There are differences in development before and after the study in the control group (ρ <0.05). There is no effect of the application of growth intervention booklet stimulation, but there is a developmental influence on premature infants aged 0-6 months in Karanganyar Regency. Conclusion: SDIDTK booklet can significantly improve the development of premature babies. It is expected that parents can provide stimulation to premature babies well to increase growth and development


2016 ◽  
Vol 7 (2) ◽  
pp. 140-144
Author(s):  
Inga N Surenkova ◽  
Galina A Suslova ◽  
Anna P Skoromets

During last five years there was increasing preterm infants, these children were born with a gestational age of 26 weeks and weighing 800 g, with severe combined pathology. Preterm infants came to the nearest polyclinics after the first stage of rehabilitation in hospitals. There are many questions how and when specialists should begin rehabilitation of such children. Specialists observes that is required an integrated approach to the rehabilitation of premature babies by analyzing the development of these children. Considering that children’s polyclinic allows monitoring children till 18 years of age, there is a possibility of observing and assisting these children during longer period. It is also very essential to realize that without an adequate intensive nursery care the negative consequences become irreversible for premature infants. Birth of a premature infant is a severe psychological stress for both parents. Often without completely realizing it, the family begins to live in conditions of high emotional stress. The department of medical rehabilitation must operate with the parents of a premature baby, in order to help them adapting to the new conditions of life. The task of differentiated medical and psychological rehabilitation can be fulfilled only by the district polyclinic in which the child will be observed until the age of 18. In the article considered features of modern rehabilitation of preterm infants in the in ambulatory-polyclinic service.


PEDIATRICS ◽  
1951 ◽  
Vol 7 (1) ◽  
pp. 19-23
Author(s):  
MYRON S. FEINSTEIN ◽  
CLEMENT A. SMITH

Absorption of N from cow's milk mixtures supplemented with equal amounts of N as casein and casein hydrolysates was determined in 20 metabolic periods on five premature infants. The supplemental protein or hydrolysate furnished from 33.3 to 46.2% of the nitrogen intake and total N fed was equivalent to 4.22 to 8.49 G. protein/kg. body weight. With either supplement from 86 to 94% of the dietary N was absorbed and neither resulted in consistently superior nitrogen absorption. Weight gains were not consistently better during either type of supplemental feeding. The evidence of equally satisfactory nitrogen absorption and weight gain would substantiate the prevailing belief that protein digestion is not impaired after premature birth.


2010 ◽  
Vol 13 (3) ◽  
pp. 160-166
Author(s):  
Suni Hariati ◽  
Yeni Rustina ◽  
Hanny Handiyani

AbstrakBayi prematur sering mengalami masalah akibat hipotermi dan berat badan rendah. Disinilah perawat anak berperan dalam memberikan stimulasi untuk mencegah terjadinya komplikasi, kecacatan, dan kematian bayi. Penelitian ini bertujuan mengetahui peningkatan berat badan dan suhu tubuh melalui terapi musik sebagai salah satu stimulasi dalam keperawatan anak. Desain penelitian menggunakan quasi-experimental pada 30 bayi prematur stabil. Musik diputar selama 30 menit/hari dalam 3 hari. Hasil penelitian menunjukkan terdapat perbedaan peningkatan berat badan yang signifikan pada hari ke-2, ke-4, dan total (p= 0,031; 0,030; dan 0,002, α= 0,05). Terdapat perbedaan peningkatan suhu tubuh yang signifikan pada hari I, II, dan III (p= 0,006; 0,002; dan 0,002, α= 0,05). APGAR menit 1 juga mempengaruhi peningkatan berat badan. Penelitian ini merekomendasikan penggunaan terapi music dalam penanganan bayi prematur di ruang perinatologi. AbstractPremature Baby often experience of low body weight and hypothermic problem. This research purposed to know weight body and temperature by music therapy. Research Design use quasi-experimental on 30 stabilize premature babies. Music turned around during 30 minute / day in 3 day. Result of research show there is difference of body weight increase which is significant on second, fourth, and total day (p= 0,031; 0,030; and 0,002, α= 0,05). There are difference of body temperature increase which is significant on I, II, and III (p= 0,006; 0,002; and 0,002, α= 0,05). There are also first minute APGAR influence at body weight increase. This research recommend to use music therapy in premature baby in perinatology room.


Author(s):  
T. V. Gnedko

The study and monitoring of international indicators of the health status of premature infants is the current vector of scientific research in neonatology.Objective. To assess the effectiveness of the nursing technologies of premature babies in the Republic of Belarus based on the analysis of long-term indicators of morbidity, mortality and survival of the infants with extremely low body weight.Material and methods. Statistical reports data were used for a retrospective analysis of epidemiological indicators for the period of 2002–2018.Results. The proportion of premature infants in the Republic of Belarus was stabilized at 4,2–4,5% increase in the absolute numbers, including those born weighing less than 1500 g. The ratio of the absolute number of alive and stillborn infants with extremely low body weight is many times higher than the initial values (p<0,05). The survival rate of infants with a body weight of 500–999g up to 1 year increased 2 times to the maximum level in 2018 (81,5%). There was an increase in the overall incidence of premature children in 2002–2010 (p<0,05) and a decrease by 2016 (p=0,001), including those born with a body weight of 500–999 g. Respiratory distress syndrome, intrauterine hypoxia and asphyxia during childbirth, an increase in the frequency of infections specific to the perinatal period (p <0,05) were registered more often. Among the children born with a body weight of 500–999 g, the incidence of congenital pneumonia for the period 2002–2009 increased to a maximum level of 263,4 ‰ (p <0,05) with a twofold decrease by 2018. The republican mortality rate of premature babies was stabilized at the level of 0,95 ‰ in the last 9 years, while the indicator was decreased 5 times among children weighing 500–999 g.Conclusion. The assessment of the long-term dynamics of the main indicators of the health status of premature infants in the Republic of Belarus testified to the effectiveness of a complex of organizational and medical measures for their nursing.


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