scholarly journals Dengue: Foreshadowing from Ancient Foe

2021 ◽  
Vol 5 (3) ◽  
Keyword(s):  
Nervous System ◽  
Dengue Hemorrhagic Fever ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
World Health ◽  
Dengue Virus Infection ◽  
Atypical Manifestations ◽  
Reticular System ◽  
Health Organization ◽  
Expanded Dengue Syndrome

Dengue is a painful, debilitating mosquito-borne disease(female mosquitoes of the Aedes genus, principally Aedes aegypti)caused by any one of four closely related dengue viruses. It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifest as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever (with or without shock). Expanded dengue syndrome(EDS) was coined by WHO in the year 2012 to describe cases, which do not fall into either dengue shock syndrome or dengue hemorrhagic fever. The atypical manifestations noted in expanded dengue are multisystem and multifaceted with organ involvement, such as liver, brain, heart, kidney, central/peripheral nervous system, gastrointestinal tract, lympho reticular system.

scholarly journals Expanded Dengue Syndrome Presenting as Acute Pancreatitis

2021 ◽  
Vol 3 (9) ◽  
pp. 01-06
Author(s):  
Richmond R Gomes
Keyword(s):  
Acute Pancreatitis ◽  
Dengue Hemorrhagic Fever ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
World Health ◽  
Serum Lipase ◽  
Atypical Manifestations ◽  
Health Organization ◽  
Upper Abdominal ◽  
Expanded Dengue Syndrome

Dengue is a painful, debilitating mosquito-borne disease(female mosquitoes of the Aedes genus, principally Aedes aegypti)caused by any one of four closely related dengue viruses.It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifests as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever(with or without shock). Expanded dengue syndrome (EDS) was coined by WHO in the year 2012 to describe cases, which do not fall into either dengue shock syndrome or dengue hemorrhagic fever. The atypical manifestations noted in expanded dengue are multisystemic and multifaceted with organ involvement, such as liver, brain, heart, kidney, central/peripheral nervous system, gastrointestinal tract, lympho reticular system. Here we present a case of 35 years old female without any comorbidities who was serologically diagnosed with dengue developed severe upper abdominal pain on 2ndafebrile day and eventually diagnosed as acute pancreatitis both by raised serum lipase and ultrasonographic evidence of swollen pancreas. She was treated conservatively and improved. Thus, all clinicians should keep in mind the possibility of acute pancreatitis as a part of expanded dengue syndrome.

scholarly journals SIADH (Syndrome of Inappropriate ADH Secretion): Perplexing Look of Dengue Fever

2021 ◽  
pp. 1-4
Author(s):  
Richmond Ronald Gomes ◽  
Keyword(s):  
Dengue Virus ◽  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Animal Studies ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
World Health ◽  
Fluid Extravasation ◽  
Health Organization ◽  
Expanded Dengue Syndrome

Dengue is a mosquito-borne disease (female mosquitoes of the Aedes genus, principally Aedes aegypti) caused by any one of four closely related dengue viruses. It is endemic in tropical and subtropical continent. World health organization (WHO) currently estimates there may be 50 -100 million dengue infections worldwide every year with over 2.5 billion people at risk of dengue. Symptomatic dengue virus infection may manifests as undifferentiated fever, classical dengue fever (with or without unusual hemorrhages), and dengue hemorrhagic fever (with or without shock). Isolated organopathy or expanded dengue syndrome (EDS) was coined by WHO in the year 2012 to describe cases, which do not fall into either dengue shock syndrome or dengue hemorrhagic fever. The atypical manifestations noted in expanded dengue are multisystemic and multifaceted with organ involvement, such as liver, brain, heart, kidney, central/peripheral nervous system, gastrointestinal tract, lympho reticular system. Dengue virus has long been considered as a non-neurotropic virus, as animal studies have shown that virus does not cross blood brain barrier. Hyponatremia may be found in association with dengue fever and is thought to be caused by peripheral fluid extravasation and resulting intravascular hypovolaemia. But hyponatremia due to syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) in Dengue fever is rare. We report a 40 years old male who was diagnosed as Dengue fever (Dengue Ns1Ag positive) with thrombocytopenia and hyponatremia. He was admitted and further investigations revealed SIADH. He responded well to cautious sodium replacement and addition of tolvaptan. He recovered completely and was discharged after one week. Thus, all clinicians should keep in mind the possibility of SIADH as a part of expanded dengue syndrome.

scholarly journals Clinical profile of dengue infection at a teaching hospital in North India

2011 ◽  
Vol 6 (07) ◽  
pp. 551-554 ◽  
Author(s):  
Ritu Karoli ◽  
Jalees Fatima ◽  
Zeba Siddiqi ◽  
Khursheed I Kazmi ◽  
Amit R Sultania
Keyword(s):  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Indian Subcontinent ◽  
Dengue Infection ◽  
Hemorrhagic Fever ◽  
North India ◽  
World Health ◽  
Health Concern ◽  
Neurological Involvement ◽  
Atypical Manifestations

Introduction: Dengue viral infections are among the most important mosquito-borne diseases of the Indian subcontinent and have become a major global public health concern. Spread of disease has led to increased recognition of atypical manifestations apart from the classical clinical features of dengue infection. Methodology: A cross-sectional study of admitted patients suspected to have dengue infection was conducted during the monsoon and post-monsoon seasons in the year 2010. Patients who had serological confirmation of dengue infection were classified according to World Health Organization definitions of dengue fever and dengue hemorrhagic fever. Clinical and biochemical parameters were compared between the two groups. Results: Out of 356 patients with suspected dengue fever enrolled in the study, 138 (39%) had serologically confirmed dengue infection. Eighty (58%) patients were males and 58 (42%) were females. Ninety-six (70%) patients had classical dengue fever while 42 (30%) had dengue hemorrhagic fever. The most common symptoms were headache (105, 76%), abdominal pain (87, 63%), vomiting (80, 58%), rash (36, 26%), and cutaneous hypersensitivity (22, 16%). Hemorrhagic manifestations were present in 55 (40%) patients. Atypical manifestations were recorded. Notably, 14% of patients had neurological involvement and 4% had acute hepatic failure. Overall mortality was 6% and all fatal cases were due to multi-organ failure. Conclusion: Dengue infection poses a huge burden to the health-care system; its spectrum ranges from mild self-limiting illness to severe fatal disease. It can have varied and multi-systemic manifestations which can go unrecognized. Clinicians should have a high index of suspicion for atypical manifestations.

scholarly journals Dengue Hemorrhagic Fever: The Sensitivity and Specificity of the World Health Organization Definition for Identification of Severe Cases of Dengue in Thailand, 1994–2005

2010 ◽  
Vol 50 (8) ◽  
pp. 1135-1143 ◽  
Author(s):  
Anon Srikiatkhachorn ◽  
Robert V. Gibbons ◽  
Sharone Green ◽  
Daniel H. Libraty ◽  
Stephen J. Thomas ◽  
...  
Keyword(s):  
World Health Organization ◽  
Sensitivity And Specificity ◽  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
World Health ◽  
The World ◽  
Health Organization

scholarly journals Assessment of World Health Organization definition of dengue hemorrhagic fever in North India

2010 ◽  
Vol 4 (03) ◽  
pp. 150-155 ◽  
Author(s):  
Prashant Gupta ◽  
Vineeta Khare ◽  
Sanjeev Tripathi ◽  
Vijaya Lakshmi Nag ◽  
Rashmi Kumar ◽  
...  
Keyword(s):  
World Health Organization ◽  
Dengue Hemorrhagic Fever ◽  
Dengue Infection ◽  
Hemorrhagic Fever ◽  
World Health ◽  
Who Criteria ◽  
Age Related ◽  
Definition Of ◽  
Health Organization

Background: Classification of symptomatic dengue according to current World Health Organization (WHO) criteria is not straightforward. In this prospective study of dengue infection during an epidemic in India in 2004, we applied the WHO classification of dengue to assess its usefulness for our patients. Methodology: The study included 145 clinically suspected cases of dengue infection of all ages. Dengue was confirmed by serological methods (IgM ELISA and HI test). WHO criteria were applied to classify dengue positive patients into Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Clinical and laboratory parameters were compared between dengue patients with bleeding and those without bleeding. Results: Out of the 50 serologically positive cases of dengue enrolled in the study, only 3 met the WHO criteria for DHF and 1 met the criteria for DSS; however, 21 (42%) cases had one or more bleeding manifestations. Conclusion: By using WHO criteria of DHF on Indian patients, all severe cases of dengue cannot be correctly classified. A new definition of DHF that considers geographic and age-related variations in laboratory and clinical parameters is urgently required.

scholarly journals PEMBERDAYAAN MASYARAKAT MELALUI PROGRAM PEMBERANTASAN SARANG NYAMUK (PSN) DALAM MENURUNKAN ANGKA KEJADIAN DEMAM BERDARAH DENGUE DI KELURAHAN PERUMNAS I PONTIANAK

2017 ◽  
Vol 13 (1) ◽  
pp. 32
Author(s):  
Tedy Dian Pradana ◽  
Ade Mayang Saraswati
Keyword(s):  
Dengue Hemorrhagic Fever ◽  
Development Program ◽  
Hemorrhagic Fever ◽  
Community Empowerment ◽  
World Health ◽  
Health Programs ◽  
School Age ◽  
Mutual Cooperation ◽  
Health Organization ◽  
The Village

World health organization (WHO) noted country Indonesia as a country with cases of dengue hemorrhagic fever (DHF) is the highest in Southeast Asia. Since 2011 in Indonesia dengue hemorrhagic fever (DHF) has claimed 595 lives out of a total of 65 432 patients person (CFR: 0.91). Dengue cases in Perumnas 1 spread to almost every pillar residents and the average affects children of school age and pre-school age and a rise in cases is high enough that in 2012 and 2013 respectively 5 and 10 cases increased to 27 cases in 2014. Community development program in the village Perumnas 1 is one effort that can be done to decrease the incidence of dengue. Based on the results of community service that has been done in the village river ox outside districts pontianak west can be concluded as follows: top priority health problems that exist in Sungai Jawi Luar Village outside is DHF, the determinant factors associated with the incidence of dengue is the knowledge, the priority problem-solving DBD in villages outside the ox river is education about dengue, establishment coordinator jumantik, film screenings dengue, DHF distribution of leaflets, posters DBD, results of evaluation of health education activities about dengue managed to increase public knowledge about dengue. Advice to Sungai Jawi Luar Village goverment should cooperate with the clinic in implementing health programs and call or invite the citizens to keep the environment with activities of mutual cooperation. Keywords: Community Empowerment, Mosquito Nest Eradication

scholarly journals Dengue worldwide: an overview of the current situation and the implications for Europe

2007 ◽  
Vol 12 (25) ◽  
Author(s):  
Collective Diseases of Environmental and Zoonotic Origin Team, ECDC
Keyword(s):  
At Risk ◽  
World Health Organization ◽  
Dengue Fever ◽  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Current Situation ◽  
Annual Incidence ◽  
World Health ◽  
The World ◽  
Health Organization

The annual incidence of dengue fever and dengue hemorrhagic fever has increased dramatically around the world in recent decades; the World Health Organization estimates that over 2.5 billion people are currently at risk from dengue viruses worldwide.

scholarly journals Utility of C-Reactive Protein Levels for Early Prediction of Dengue Severity in Adults

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Chien-Chih Chen ◽  
Ing-Kit Lee ◽  
Jien-Wei Liu ◽  
Shi-Yu Huang ◽  
Lin Wang
Keyword(s):  
Characteristic Curve ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
World Health ◽  
Severe Dengue ◽  
Early Prediction ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Health Organization

Dengue has broad clinical presentation with unpredictable clinical evolution and outcome. We aimed to evaluate the utility of C-reactive protein (CRP) levels for distinguishing between mild and severe cases in the early phase of the dengue illness. We retrospectively evaluated adults with dengue from 2006 to 2014, according to 1997 and 2009 World Health Organization (WHO) criteria for severity. Of 191 included patients, 32.9% had nonshock dengue hemorrhagic fever (DHF), 3.1% dengue shock syndrome (DSS), and 7.9% severe dengue. The risk of DHF/DSS and severe dengue is significantly related to the increasing levels of CRP. Of 191 patients, 97 had CRP levels measured during the febrile (days 1–3); 85 during the critical (days 4–6); and 9 during the convalescent (days 7–10) illness phases. During the febrile phase, there was significant higher CRP level for DSS versus DF/nonshock DHF and severe dengue versus nonsevere dengue, with CRP cutoff level 30.1 mg/L (area under the receiver operating characteristic curve (AUC), 0.938; 100% sensitivity, 76.3% specificity) and 24.2 mg/L (AUC, 0.717; 70% sensitivity, 71.3% specificity), respectively. Our study highlights the utility of the CRP levels in early prediction of DSS and severe dengue in adult patients.

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