scholarly journals Complications of pancreatitis: features of the course and tactics of treatment

2020 ◽  
Vol 48 (3) ◽  
pp. 38-43
Author(s):  
D. A. Hontsariuk ◽  
M. V. Patratii

The aim of this article is to draw attention of gastroenterologists, surgeons and primary care physicians to the features of the course of pancreatitis complications, which tend to have an acute course and are a complex process that causes medical errors and life tragedies. The importance of complications of pancreatitis such as cysts, pseudocysts, fistulas, cholestatic syndrome, portal hypertension syndrome, bleeding from varicose veins of the esophagus, stomach and erosive-ulcerative secondary gastroduodenal processes is emphasized. Attention is focused on the mechanisms of development of these complications, features of the clinical course, management tactics of such patients, depending on the location of the complications, which is important for the treatment strategy (conservative or surgical). The peculiarities of the clinical picture of the syndrome of compression of neighboring organs, thrombosis of the hepatic and splenic veins, biliodigestive bleeding, including hemobilia, bleeding from the large and small duodenal papilla, are directly related to the analytical approach regarding the diagnosis of these complications. Angiographic techniques are considered to be the most effective diagnostic techniques, which include celiacography, upper mesentericography, percutaneous and transhepatic portography. It is indicated that on their basis, techniques for stopping bleeding have been developed, namely endovascular catheter hemostasis.

1993 ◽  
Vol 7 (2) ◽  
pp. 59-65 ◽  
Author(s):  
John R. Wanamaker ◽  
Hayes H. Wanamaker ◽  
Bernard Kotton ◽  
Greg D. Akers ◽  
Pierre Lavertu

Schwannomas are benign neoplasms arising from the peripheral nerve sheath. The sinonasal tract is an unusual location for these neoplasms. Because of their rarity, few series have been reported. Five previously unreported cases of schwannomas of the nose and paranasal sinuses are presented that illustrate the spectrum of disease. The clinical presentation, diagnostic work-up, clinical course, and diverse therapeutic approaches will be discussed. A management philosophy based on the diversity of these tumors and their clinical behavior, and incorporating the new diagnostic and therapeutic tools available to the clinician will be presented. The implications of newer diagnostic techniques including sinonasal endoscopy, magnetic resonance imaging, and immuno-chemistry in the diagnosis and treatment of these tumors will be discussed.


Flebologiia ◽  
2017 ◽  
Vol 11 (1) ◽  
pp. 37 ◽  
Author(s):  
K. V. Mazayshvili ◽  
S. S. Akimov ◽  
T. V. Khlevtova ◽  
A. V. Sukhanov ◽  
V. A. Angelova ◽  
...  

Therapy ◽  
2019 ◽  
Vol 6_2019 ◽  
pp. 87-93
Author(s):  
Bobkova I.N. Bobkova ◽  
Gussaova S.S. Gussaova ◽  
Stavrovskaya E.V. Stavrovskaya ◽  

2003 ◽  
Vol 18 (3) ◽  
pp. 110-122 ◽  
Author(s):  
A Jawien ◽  
T Grzela ◽  
A Ochwat

Objective: To study the prevalence, clinical expression and risk factors of chronic venous insufficiency (CVI) in 40,095 Polish adults. Method: This was a multicentre cross-sectional study with 803 participating primary care physicians. Results: The study population was mainly female (84%). The mean age was 44.8 years. Of the total population, 10% presented with oedema, 34.3% had varicose veins, with approximately the same proportion in males and females and 1.5% presented with past or active ulceration. A similar prevalence of CVI to that observed in the developed countries was reported in Poland. Obesity, the number of pregnancies and a positive family history were found to be risk factors for CVI. Female gender was not shown to be a risk factor for varicose veins. Conclusions: The relationship between the presence of symptoms and signs of CVI was high, whatever the gender. Thus, the previously described dominance of the disease in females is losing its significance.


2019 ◽  
pp. 20-28
Author(s):  
Nery Lamothe ◽  
Mara Lamothe ◽  
Alejandro Alonso-Altamirano ◽  
Pedro A Lamothe

The Bayesian concept is complex and contrary to intuition, but it is fundamental in the practice of medicine as well as in biotechnological development. We expect that a tragedy of ignoring the Bayesian concept will result clear to the reader who should acquire the tools to recognize its meaning, as well as, its use; but especially, to visualize the serious consequences of ignoring it. The physician is not mystically fascinated for knowing what percentage of patients who has prostate cancer have no symptoms (47%), urinary frequency (38%), urinary urgency (10%), decreased urine stream (23%) or hematuria (1.4%). What the physician and every patient want and vitally need to know is the probability of having prostate cancer, giving that he has one or more of those symptoms. Keywords: Medical Errors; Iatrogenic disease; Sensitivity and specificity; Diagnostic Techniques and procedures


2021 ◽  
pp. 54-58
Author(s):  
Yu.Yu. Yarov

The issues of clarifying the key mechanisms of development and course of generalized periodontitis in different conditions of reactivity of the organism remain relevant. The aim of the research is study of the peculiarities of course of the inflammatory-destructive process in the periodontium according to the dynamics of clinical and paraclinical indicators depending on the state of reactivity of the body in the conditions of modeling hyper- and hyporeaction. Materials and methods. The experiments were performed on 24 adult not purebred dogs weighing 8-12 kg. The animals were divided into three equal groups. In the first group, drugs that disrupt the reactivity of the organism were not used (normoreactivity of the organism). In the second group drugs simulated the state of hyperreactivity, and in the third they provoked the condition of the hyporeactivity of the organism. The condition of periodontal tissues was assessed initially, on the 14th and 28th day of observation of clinical and paraclinical parameters (creviculars liquor, PMA indices, PI Russell, GI Fedorov-Volodkina, Kulazhenko's test). Results. On the 14th day of modelling the states of hyper- and hyporeactivity of the organism a number of differences in the nature of inflammation in periodontal tissues were revealed in animals of different groups. Control of the amount of creviculars liquor increased in 1,1 times, PMA indices, PI Russell, GI Fedorov-Volodkina, Kulazhenko's test, respectively, in 1,12; 1,19; 1,33 and 1,29 times (p <0,05). On the 28th day of the experiment, significant differences in the intensity of the destructive process in animals with unchanged and changed reactivity of the organism attracted attention. Thus, in cases of normoreactivity the depth of periodontal pockets reached 3 mm, the mobility of the teeth was I degree, with the changed - the depth of periodontal pockets was 5-6 mm, the mobility of the teeth was II-III degree. The amount of creviculars liquor, reflecting the intensity of the inflammatory reaction, increased compared with the 14th day, 1,3 times (p <0,05); PMA index, which characterizes the prevalence of gingivitis, and the Kulazhenko test probably did not change (p> 0,05); Russell's PI index, which indicates a pronounced intensity of inflammatory-destructive periodontal lesions, increased 2,05 times (р <0,05). Conclusions. Thus, in cases of normoreactivity of organism the inflammatory-destructive process in periodontium has moderate nature; when modelling the hyper- and hyporeactivity of the organism it acquires the character of “rapidly progressing periodontitis”. Therefore, it is necessary to continue studying the question of explaining the mechanism of different clinical course of the inflammatory-destructive process with changed and unchanged reactivity of the organism.


2014 ◽  

This issue of AM:STARs, Hot Topics in Adolescent Health, presents a wide array of articles exploring some of the most exciting advances and controversies in adolescent health. These topics and other evolving areas are presented to guide the reader toward providing state of the art clinical care to adolescents, as well as reviewing new research that will shape the future of adolescent health. Topics include: Nutritional and metabolic controversies including the diagnosis of gluten intolerance, vitamin D deficiency and metabolic syndrome in adolescents, and the use of bariatric surgery to treat the comorbidities of adolescent obesity. New diagnostic considerations, including updated DSM-5 diagnostic criteria for mental health disorders such as mood dysregulation, eating disorders, and ADHD. Reproductive health advances including new diagnostic techniques and treatment regimens for HIV and other sexually transmitted infections, as well as the expanding use of long-acting reversible contraceptives. New frontiers in adolescent medicine including office-based management of opiate addiction, support of gender nonconforming youth, and the use of mindfulness practices in the care of a variety of conditions. AM:STARs: Adolescent Medicine: State of the Art Reviews is the official publication of the American Academy of Pediatrics Section on Adolescent Health. Published 3 times per year, the journal offers adolescent medicine specialists and other primary care physicians who treat adolescent patients with state of the art information on all matters relating to adolescent health and wellness.


1989 ◽  
Vol 5 (4) ◽  
pp. 579-600 ◽  
Author(s):  
David Blumenthal ◽  
Richard Zeckhauser

Genetic diagnostic techniques increasingly permit the detection of predisposition to illness long before the onset of the disease process itself. Medicine is on the verge of becoming a predictive science as well as a diagnostic and therapeutic one. Genetic diagnosis could have profound effects on many aspects of our health care system, including the prestige and effectiveness of preventive medicine, the competitive behavior of health care organizations and insurance companies, access to private health insurance, the ability of primary care physicians to serve as gatekeepers, and other matters. This article examines the range of potential effects of the new genetic diagnostics on the organization and financing of health care. For purposes of illustration the authors examine in detail the possible consequences of genetic tests for predisposition to two diseases: Reye's Syndrome and lung cancer in smokers.


2021 ◽  
Vol 25 (1) ◽  
pp. 27-33
Author(s):  
Olga Yu. Kuznetsova ◽  
Anna V. Lubimova ◽  
Karina V. Ovakimyan ◽  
Olga I. Frolova ◽  
Olga S. Zamyatina ◽  
...  

INTRODUCTION: The sudden appearance of a new coronavirus infection in the world has posed difficult challenges for science to determine the main clinical manifestations of this disease, as well as to approve standards for diagnosis, treatment and prevention. Research of the symptoms of mild COVID-19 is continuing. The data obtained in such studies are particularly relevant for primary care physicians. THE AIM: To evaluate the features of the clinical course of COVID-19 among students of the North-Western State Medical University named after I.I. Mechnikov, placed in the observatory, during the first and second waves of rising morbidity. MATERIALS AND METHODS: The study was conducted on the basis of the observatory of the NWSMU named after I.I. Mechnikov in two stages: in the period from 21.04.2020 to 31.08.2020 (the first wave) and from 16.09.2020 to 31.12.2020 (the second wave). Demographic, epidemiological, and clinical-anamnestic data were recorded in all participants of the study. RESULTS: The study involved 309 people: 39.8% men (n = 123) and 58.9% women (n = 182). The average age of the respondents was 21.5 2.6 years. The number of participants in the first and second waves was 113 and 196 people, respectively. The average age of participants with COVID-19 in the first wave was 1.5 years less and was 21.2 2.5 years (р 0.001). There was a significant increase in the frequency of the following symptoms: dry cough, loss of smell, headache, general weakness, increased body temperature to 38.0 С, nasal congestion (р 0.05) in students who were monitored in the second wave of increased incidence of COVID-19 compared to the first. The frequency of symptoms such as chest congestion, lower back pain, and fever above 38.0 С significantly decreased (р 0.05). There was a significant decrease in the incidence of viral pneumonia in patients who were observed during the second wave, compared with the data obtained during the first wave (р 0.001).


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