Recent trends and advances in 3d printing for biomedical applications

3D printing has revolutionized the technological field with its rapid growth and broad popularity throughout the globe. It is one of the most sought out techniques being used because of the speed and development it offers in production, customization features, and numerous diverse opportunities it provides in every field. It has found applications in fields ranging from automobiles to the architecture industry. It has also seen tremendous growth in the medical field in recent years, but the growth hasn’t been significant as in other fields due to the limitations in the use of materials it can be integrated with. This review article provides the current scenario of 3d printing in medical fields, such as the bioprinting of tissues and the integration of nanotechnology in 3d-printing of biomaterials. Though the article focuses on tissue engineering, it also sheds light on the various 3d printing methods outlining how different forms of 3d printing techniques are contributing to the medical field. Various materials which have been used as biomaterials has also been discussed along with their usages and contribution in different 3d printing techniques and their respective advantages and disadvantages. Along with the industry trends and advantages of 3d printing in the medical field, this review article also discusses the limitations and potential threats of this technology.

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A review of 3D printing processes and materials for soft robotics

Rapid Prototyping Journal ◽

10.1108/rpj-11-2019-0302 ◽

2020 ◽

Vol 26 (8) ◽

pp. 1345-1361 ◽

Cited By ~ 1

Author(s):

Yee Ling Yap ◽

Swee Leong Sing ◽

Wai Yee Yeong

Keyword(s):

3D Printing ◽

Soft Robotics ◽

Soft Robots ◽

Content Type ◽

Advantages And Disadvantages ◽

The Future ◽

3D Printed ◽

Multiple Materials ◽

Printing Processes ◽

Printing Techniques

Purpose Soft robotics is currently a rapidly growing new field of robotics whereby the robots are fundamentally soft and elastically deformable. Fabrication of soft robots is currently challenging and highly time- and labor-intensive. Recent advancements in three-dimensional (3D) printing of soft materials and multi-materials have become the key to enable direct manufacturing of soft robots with sophisticated designs and functions. Hence, this paper aims to review the current 3D printing processes and materials for soft robotics applications, as well as the potentials of 3D printing technologies on 3D printed soft robotics. Design/methodology/approach The paper reviews the polymer 3D printing techniques and materials that have been used for the development of soft robotics. Current challenges to adopting 3D printing for soft robotics are also discussed. Next, the potentials of 3D printing technologies and the future outlooks of 3D printed soft robotics are presented. Findings This paper reviews five different 3D printing techniques and commonly used materials. The advantages and disadvantages of each technique for the soft robotic application are evaluated. The typical designs and geometries used by each technique are also summarized. There is an increasing trend of printing shape memory polymers, as well as multiple materials simultaneously using direct ink writing and material jetting techniques to produce robotics with varying stiffness values that range from intrinsically soft and highly compliant to rigid polymers. Although the recent work is done is still limited to experimentation and prototyping of 3D printed soft robotics, additive manufacturing could ultimately be used for the end-use and production of soft robotics. Originality/value The paper provides the current trend of how 3D printing techniques and materials are used particularly in the soft robotics application. The potentials of 3D printing technology on the soft robotic applications and the future outlooks of 3D printed soft robotics are also presented.

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Universal CubeSat Platform Design Technique

MATEC Web of Conferences ◽

10.1051/matecconf/201817901002 ◽

2018 ◽

Vol 179 ◽

pp. 01002

Author(s):

Zhiyong Chen

Keyword(s):

3D Printing ◽

System Development ◽

Low Cost ◽

Fem Simulation ◽

Frame Structure ◽

Scientific Impact ◽

Advantages And Disadvantages ◽

Small Parts ◽

3D Printing Technique ◽

Printing Techniques

This article summarizes cubesat technology, provides examples of their scientific impact, and describes the design and the manufacturing of a Cubesat platform. As for the design of the overall frame structure of the CubeSat, we have searched a lot of literature and consulted many predecessors' designs, and collected many satellite structure images. After analyzing the data, we aimed at all kinds of different structures’ advantages and disadvantages, finally we got a best design. It is a satellite of cubic shape (10 cm per side), weighing approximately 1kg, based on the creation of a central body made of different material using the 3D-Printing techniques. The 3D-Printing technique has several advantages including fast implementation, accuracy in manufacturing small parts and low cost. Moreover, concerning the construction of a small satellite, this technique is very useful thanks to the accuracy achievable in details, which are sometimes difficult and expensive to realize with the use of tools machine. The structure must be able to withstand the launch loads. For this reason, several simulations using an FEM simulation and an intensive vibration test campaign will be performed in the system development and test phase.

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Materials and technical innovations in 3D printing in biomedical applications

Journal of Materials Chemistry B ◽

10.1039/d0tb00034e ◽

2020 ◽

Vol 8 (15) ◽

pp. 2930-2950 ◽

Cited By ~ 9

Author(s):

Hiroyuki Tetsuka ◽

Su Ryon Shin

Keyword(s):

3D Printing ◽

Biomedical Applications ◽

New Materials ◽

Technical Innovations ◽

Printing Techniques

This review highlights the recent advancements of new materials and 3D printing techniques developed to address the unfulfilled needs of the conventional 3D printing methodologies in biomedical applications.

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Three-Dimensional Printing Constructs Based on the Chitosan for Tissue Regeneration: State of the Art, Developing Directions and Prospect Trends

Materials ◽

10.3390/ma13112663 ◽

2020 ◽

Vol 13 (11) ◽

pp. 2663 ◽

Cited By ~ 4

Author(s):

Farnoosh Pahlevanzadeh ◽

Rahmatollah Emadi ◽

Ali Valiani ◽

Mahshid Kharaziha ◽

S. Ali Poursamar ◽

...

Keyword(s):

3D Printing ◽

Biomedical Applications ◽

Three Dimensional ◽

Historical Background ◽

Patient Specific ◽

Technical Problems ◽

Precise Adjustment ◽

Developing Directions ◽

Traditional Manufacturing ◽

Printing Techniques

Chitosan (CS) has gained particular attention in biomedical applications due to its biocompatibility, antibacterial feature, and biodegradability. Hence, many studies have focused on the manufacturing of CS films, scaffolds, particulate, and inks via different production methods. Nowadays, with the possibility of the precise adjustment of porosity size and shape, fiber size, suitable interconnectivity of pores, and creation of patient-specific constructs, 3D printing has overcome the limitations of many traditional manufacturing methods. Therefore, the fabrication of 3D printed CS scaffolds can lead to promising advances in tissue engineering and regenerative medicine. A review of additive manufacturing types, CS-based printed constructs, their usages as biomaterials, advantages, and drawbacks can open doors to optimize CS-based constructions for biomedical applications. The latest technological issues and upcoming capabilities of 3D printing with CS-based biopolymers for different applications are also discussed. This review article will act as a roadmap aiming to investigate chitosan as a new feedstock concerning various 3D printing approaches which may be employed in biomedical fields. In fact, the combination of 3D printing and CS-based biopolymers is extremely appealing particularly with regard to certain clinical purposes. Complications of 3D printing coupled with the challenges associated with materials should be recognized to help make this method feasible for wider clinical requirements. This strategy is currently gaining substantial attention in terms of several industrial biomedical products. In this review, the key 3D printing approaches along with revealing historical background are initially presented, and ultimately, the applications of different 3D printing techniques for fabricating chitosan constructs will be discussed. The recognition of essential complications and technical problems related to numerous 3D printing techniques and CS-based biopolymer choices according to clinical requirements is crucial. A comprehensive investigation will be required to encounter those challenges and to completely understand the possibilities of 3D printing in the foreseeable future.

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3D Printed Sensors for Biomedical Applications: A Review

Sensors ◽

10.3390/s19071706 ◽

2019 ◽

Vol 19 (7) ◽

pp. 1706 ◽

Cited By ~ 28

Author(s):

Tao Han ◽

Sudip Kundu ◽

Anindya Nag ◽

Yongzhao Xu

Keyword(s):

3D Printing ◽

Biomedical Applications ◽

Market Survey ◽

Healthcare Applications ◽

Biomedical Sensing ◽

Printed Sensors ◽

3D Printed ◽

The Individual ◽

Work Done ◽

Printing Techniques

This paper showcases a substantial review on some of the significant work done on 3D printing of sensors for biomedical applications. The importance of 3D printing techniques has bloomed in the sensing world due to their essential advantages of quick fabrication, easy accessibility, processing of varied materials and sustainability. Along with the introduction of the necessity and influence of 3D printing techniques for the fabrication of sensors for different healthcare applications, the paper explains the individual methodologies used to develop sensing prototypes. Six different 3D printing techniques have been explained in the manuscript, followed by drawing a comparison between them in terms of their advantages, disadvantages, materials being processed, resolution, repeatability, accuracy and applications. Finally, a conclusion of the paper is provided with some of the challenges of the current 3D printing techniques about the developed sensing prototypes, their corresponding remedial solutions and a market survey determining the expenditure on 3D printing for biomedical sensing prototypes.

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A Critical Review on 3D-printed Dosage Forms

Current Pharmaceutical Design ◽

10.2174/1381612825666181206124206 ◽

2019 ◽

Vol 24 (42) ◽

pp. 4957-4978 ◽

Cited By ~ 7

Author(s):

Ilias El Aita ◽

Hanna Ponsar ◽

Julian Quodbach

Keyword(s):

3D Printing ◽

Drug Release ◽

Critical Evaluation ◽

Dosage Forms ◽

Review Article ◽

Current Status ◽

Comprehensive Overview ◽

Pharmaceutical Dosage Forms ◽

Advantages And Disadvantages ◽

Pharmaceutical Application

Background: In the last decades, 3D-printing has been investigated and used intensively in the field of tissue engineering, automotive and aerospace. With the first FDA approved printed medicinal product in 2015, the research on 3D-printing for pharmaceutical application has attracted the attention of pharmaceutical scientists. Due to its potential of fabricating complex structures and geometrics, it is a highly promising technology for manufacturing individualized dosage forms. In addition, it enables the fabrication of dosage forms with tailored drug release profiles. Objective: The aim of this review article is to give a comprehensive overview of the used 3D-printing techniques for pharmaceutical applications, including information about the required material, advantages and disadvantages of the respective technique. Methods: For the literature research, relevant keywords were identified and the literature was then thoroughly researched. Conclusion: The current status of 3D-printing as a manufacturing process for pharmaceutical dosage forms was highlighted in this review article. Moreover, this article presents a critical evaluation of 3D-printing to control the dose and drug release of printed dosage forms.

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Biomaterials and 3D printing techniques used in the medical field

Journal of Medical Engineering & Technology ◽

10.1080/03091902.2021.1893845 ◽

2021 ◽

pp. 1-13

Author(s):

Abhay Mishra ◽

Vivek Srivastava

Keyword(s):

3D Printing ◽

Medical Field ◽

Printing Techniques

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3D-Printed Microfluidics and Potential Biomedical Applications

Frontiers in Nanotechnology ◽

10.3389/fnano.2021.609355 ◽

2021 ◽

Vol 3 ◽

Author(s):

Priyanka Prabhakar ◽

Raj Kumar Sen ◽

Neeraj Dwivedi ◽

Raju Khan ◽

Pratima R. Solanki ◽

...

Keyword(s):

3D Printing ◽

Biomedical Applications ◽

Chemical Properties ◽

Microfluidic Devices ◽

Microfluidic Chips ◽

3D Printers ◽

Broad Variety ◽

3D Printed ◽

Diagnostic Technologies ◽

Printing Techniques

3D printing is a smart additive manufacturing technique that allows the engineering of biomedical devices that are usually difficult to design using conventional methodologies such as machining or molding. Nowadays, 3D-printed microfluidics has gained enormous attention due to their various advantages including fast production, cost-effectiveness, and accurate designing of a range of products even geometrically complex devices. In this review, we focused on the recent significant findings in the field of 3D-printed microfluidic devices for biomedical applications. 3D printers are used as fabrication tools for a broad variety of systems for a range of applications like diagnostic microfluidic chips to detect different analytes, for example, glucose, lactate, and glutamate and the biomarkers related to different clinically relevant diseases, for example, malaria, prostate cancer, and breast cancer. 3D printers can print various materials (inorganic and polymers) with varying density, strength, and chemical properties that provide users with a broad variety of strategic options. In this article, we have discussed potential 3D printing techniques for the fabrication of microfluidic devices that are suitable for biomedical applications. Emerging diagnostic technologies using 3D printing as a method for integrating living cells or biomaterials into 3D printing are also reviewed.

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Recent Trends in 3D Printing of Dental Models

Additive Manufacturing ◽

10.4018/978-1-5225-9624-0.ch018 ◽

2020 ◽

pp. 424-444

Author(s):

Kayalvizhi Mohan

Keyword(s):

3D Printing ◽

Rapid Prototyping ◽

Dental Implants ◽

Recent Trend ◽

Image Acquisition ◽

Different Types ◽

Dental Models ◽

Recent Trends ◽

Printing Techniques

This chapter introduces the recent trend in 3D printing (3DP) in dentistry. The advantage and disadvantages of 3DP are discussed. It elaborates on different types of 3DP techniques involved and their significance. The chapter further discuss about the biomaterial used. It also describes the complete steps involved in 3DP such as image acquisition, modeling, segmentation, and printing techniques. The merits and demerits of the different methodologies pertaining to steps involved in 3DP are illustrated. Rapid prototyping in dental implants is discussed in detail. It ends with review of a case study in implementing the technique.

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