scholarly journals Probiotic Supplementation and Its Effect on Weight and Feed tolerance in Preterm Low Birth Weight Newborns: A Clinical Trial

2017 ◽  
Vol 39 (2) ◽  
pp. 82-87
Author(s):  
Sadeka Choudhury Moni ◽  
MA Mannan ◽  
Sanjoy Kumer Dey ◽  
Arjun Chandra Dey ◽  
Debashish Saha ◽  
...  

Background: Establishment of full enteral feed is a major challenge in the care of preterm low birth weight (LBW) neonates. Probiotics are live microbial supplements that colonize preterm bowel with favourable flora, improve tolerance to feed and promotes growth of these premies.Objective: To determine the effect of probiotic supplementation on feed tolerance, postnatal weight gain, duration of hospital stay in preterm low birth weight babies.Methods : This prospective clinical trial was conducted in the Neonatal Intensive Care Unit (NICU), Bangabandhu Sheikh Mujib Medical University, (BSMMU) from February, 2012 to November, 2012. A total of 65 preterm, low birth weight ( LBW) newborns were included in this study. A multistrain probiotic suspension was given once daily to the infants in probiotic group along with expressed breast milk (EBM) through the nasogastric tube/ dropper from the first day of feed which was continued till attainment of full feed. Those in controls received only expressed breast milk. Weight, feed volume increment, features of intolerance were followed up daily. Relevant investigations were done whenever indicated.Results: The mean time to reach full enteral feed in probiotic and control group was 13.71±3.4 vs 16.53±6.13; p<0.05. But weight gain was not affected by supplementation. Hospital stay was shorter in supplemented group.Conclusion: Probiotic supplementation in preterm low birth weight babies improves feed tolerance and decreases hospital stay but does not affect weight gain.Bangladesh J Child Health 2015; VOL 39 (2) :82-87

2021 ◽  
Vol 71 (3) ◽  
pp. 1080-84
Author(s):  
Arouj Waqqas ◽  
Zeeshan Ahmed ◽  
Huma Farrukh ◽  
Hina Khalid ◽  
Talal Waqar

Objective: To observe the effect of fortification of expressed human breast milk with olive oil and skimmed milk in improving weight gain in very low birth weight neonates and shortening their length of hospital stay. Study Design: A comparative prospective study. Place and Duration of Study: Combined Military Hospital Lahore, from Mar 2018 to Mar 2019. Methodology: Neonates admitted with very low birth weight and gestational age of <34 weeks were included in study. Sixty babies were enrolled using non-probability consecutive sampling; random number table used to allocate them into a fortifycation group and a control group. The control group received expressed milk alone, while olive oil oneml twice daily and skimmed milk one gram in every third feed were added to expressed milk in the fortification group. Results: The study comprised of 60 neonates, with 30 in each of the groups. Weight gain was 24.83 ± 5.63 in the fortification group and 11.72 ± 3.95 in the control group (p≤0.001). Mean hospital stay was 20.57  16.511 in the fortification group and 27.67 ±  8.89 in the control group (p≤0.043). Conclusion: Olive oil and skimmed milk fortification of breast milk was effective for weight gain and reducing length of hospital stay in very low birth weight neonates.


2021 ◽  
Vol 55 (9) ◽  
Author(s):  
Fay S. De Ocampo ◽  
Ma. Esterlita Villanueva-Uy

Objective. To determine the effectiveness of Kangaroo Mother Care (KMC) in increasing the rate of weight gain and decreasing hypothermia, apnea, and sepsis rate, and shorten hospital stay among low-birth-weight infants. Methods. Very low birth weight (VLBW) infants (≤1500 grams) were randomized to either the KMC or conventional care group. KMC provided skin-to-skin contact at least 6 hours per day while the conventional group received the usual care in the newborn intensive care unit (NICU). Daily weight measurements and weekly measurements of length, head, and chest circumference were recorded until discharge. Occurrence of hypothermia, apnea, sepsis, and length of stay was noted. Results. KMC group had a higher mean weight gain per day (p=0.0102). There was no difference in the length, head, and chest circumference between the two groups. Sepsis and apnea rates were not significant between the two groups. Significantly more neonates experience hypothermia in the control group (p<0.0069). Conclusion. KMC is effective in increasing the weight per day compared with the control group. KMC protects the neonates against hypothermia. There is not enough evidence to show a difference in the incidence of sepsis, apnea, and the length of hospital stay between the two groups.


2021 ◽  
Vol 55 (9) ◽  
Author(s):  
Janelle Margaux M. Logronio ◽  
Maria Esterlita T. Villanueva-Uy ◽  
Socorro De Leon-Mendoza

Background. The Neonatal Intensive Care Unit (NICU) admission at the Philippine General Hospital (PGH) exceeds total bed capacity. Decreasing admissions to the NICU would prevent overcrowding of patients, improve patient care, reduce hospital stay, and reduce predisposition to hospital-acquired infections. Objective. To determine the effect of continuous versus intermittent Kangaroo Mother Care (KMC) on weight gain and duration of hospital stay among low birth weight (LBW) neonates weighing 1,800 - 2,220 grams. Methods. Forty-six (46) stable LBW were randomized to either continuous (≥12 hours in the maternity ward) or intermittent (≤6 hours in the NICU step-down unit) KMC groups. Daily weight and weekly length, head and chest circumference until discharge, and duration of hospital stay were measured. Data were analyzed using the Mann-Whitney U-test and Fisher's exact test. Results. Infants in continuous KMC had an average weight gain of 50 grams/day (p=0.509) and had an average duration of hospital stay of 3 days (p=0.218). Results were not statistically different from intermittent KMC. Conclusion. There was no evidence to show that weight gain and duration of hospital stay among infants in continuous KMC were significantly different from those in the intermittent KMC group.


2021 ◽  
Vol 8 (9) ◽  
pp. 1575
Author(s):  
Kumari Mohini ◽  
Munna Lal Jaipal ◽  
Surender Singh Bisht ◽  
Amita Tyagi

Background: Low birth weight (LBW) babies have more the risk of the neurological complications, physiological problems and mental retardation. Topical massage with natural oil is routinely practiced in India. The positive effects of massage are weight gain, improved sleep/wake pattern, decreased the stress, early discharge from the neonatal intensive care unit (NICU), improve the skin integrity and enhanced parent’s infant bonding.Methods:This prospective interventional randomised comparative study was conducted among 64 LBW babies at Paediatric department of Swami Dayanand hospital (SDH), Delhi. Out of which 31 were in intervention group and 33 were in control group.  In the intervention group, mothers were encouraged to massage their babies with 10 ml of coconut oil for 15 min, twice a day until 10 days of life. Those allocated to the control group were received care as usual. Weight and head circumference was measured at enrolment and on day 11 in both the groups.Results: Basic characteristics of neonates of intervention and control group were almost similar. Mean weight gain in intervention group was 352.26±101.05 g while it was 209.70±124.66 g in control group (p=0.0001). Similarly mean weight gain velocity was significantly higher in intervention group (32.02±19.19 g/day) as compared to control group (19.09±11.33 g/day, p=0.0001).Conclusions:The present study supports significant increase in weight gain in LBW preterm and term neonates with coconut oil massage. Coconut oil is easily available in the market and it should be recommended to LBW babies for their better weight gain.


2018 ◽  
Vol 3 (2) ◽  

Low birth weight infants are highly vulnerable as they have to make several adjustments to achieve equilibrium in metabolic processes, circulation and breathing. Therefore, the aim of this study was to examine the effect of Kangaroo Care on physiological measurements and weight in Low birth weight infants. The study was conducted at the neonatal Intensive Care Units in Menoufia University hospital (Shebin El-Kom) and Mansheat Sultan village (Menoufia). The study sample was composed of sixty Low birth weight infants. A simple random sample was done to assign them into study and control groups (n=30). A quasi experimental design was used. The results of this study showed that low birth weight infants who attended kangaroo care sessions had better weight gain (2.06±0.21 Vs1.90±0.26), fewer duration of hospitalization (11.33+1.81Vs 15.57+2.81) and better physiological adjustments than low birth weight infants in the control group. Therefore, it was concluded that low birth weight infants who attended kangaroo care sessions had better physiological measurements, weight gain and shorter duration of hospitalization than low birth weight infants in the control group. It was recommended that kangaroo care sessions should be conducted at neonatal intensive care units.


2018 ◽  
Vol 41 (2) ◽  
pp. 101-109
Author(s):  
Md Jamshed Alam ◽  
Md Kamrul Ahsan Khan ◽  
Nazmun Nahar ◽  
Sanjoy Kumer Dey ◽  
Md A Mannan ◽  
...  

Introduction: Anemia of prematurity (AOP) is a common problem of very low birth weight babies. Blood transfusion is a necessity when it occurs in moderate to severe form putting the child in to the risk of transfusion related complications. Erythropoietin, a potent stimulator of hemopoesis is available in breast milk in good amount and absorbed intact under physiologic condition. In this background oral recombinant human erythropoietin (rhEPO) can be a useful alternative to its subcutaneous administration in prevention of AOP.Objective: To evaluate the efficacy of oral rhEPO in the prevention of AOP in very low birth weight (VLBW) neonates.Methods: This randomized controlled study conducted in the NICU of BSMMU over one year. Total 60 preterm (<34 weeks)VLBW (<1500g) infants were enrolled and randomly divided into Control (group-I), Oral (group-II) and Subcutaneous (group III). Experimental groups (group-II & group-III) received rhEPO 400 IU/Kg, 3 times weekly in oral and subcutaneous (S/C) route respectively and continued for 2 weeks (Total 6 doses). Therapy was initiated 14 days after birth when the baby achieved oral feeding of at least 50 ml/kg/day of breast milk. All infants received oral iron and folic acid supplementation up to 12 weeks of postnatal age. Transfusion data were recorded. Anthropometric and hematological assessments were done at 2, 4, 6 and 12 weeks of age.Results: Baseline clinical characteristics and hematological values were almost similar in all groups. Mean hemoglobin were 11.34±0.68gm/dl, 11.88±0.54gm/dl& 12.12±1.32 gm/dl, the mean hematocrit were 34.11±2.03%, 35.66±1.65% & 36.38±3.97% and the mean reticulocyte were 7.56±2.48%, 9.85±1.50% & 9.22±3.11% in the control, oral and subcutaneous group respectively and the differences are statistically significant (p<0.05).Weight gain was higher in the intervention group at 6 and 12 weeks follow up than the control group(p<0.05).Only 2 (5.25%) infants, one in each of the intervention groups required blood transfusion, compared to 6 (31.5%) infants in control group (p<0.01).Conclusion: Oral EPO is as good as subcutaneous use of EPO in stimulating erythropoesis, maintaining HCT and Hb at high level and is safe in preterm baby.Bangladesh J Child Health 2017; VOL 41 (2) :101-109


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Priya Singh Rangey ◽  
Megha Sheth

Background. Massage therapy (MT) and kangaroo mother care (KMC) are both effective in increasing the weight and reducing length of hospital stay in low birth weight preterm infants but they have not been compared.Aim. Comparison of effectiveness of MT and KMC on body weight and length of hospital stay in low birth weight preterm (LBWPT) infants.Method. 30 LBWPT infants using convenience sampling from Neonatal Intensive Care Unit, V.S. hospital, were randomly divided into 2 equal groups. Group 1 received MT and Group 2 received KMC for 15 minutes, thrice daily for 5 days. Medically stable babies with gestational age < 37 weeks and birth weight < 2500 g were included. Those on ventilators and with congenital, orthopedic, or genetic abnormality were excluded. Outcome measures, body weight and length of hospital stay, were taken before intervention day 1 and after intervention day 5. Level of significance was 5%.Result. Data was analyzed using SPSS16. Both MT and KMC were found to be effective in improving body weight (P= 0.001,P= 0.001). Both were found to be equally effective for improving body weight (P= 0.328) and reducing length of hospital stay (P= 0.868).Conclusion. MT and KMC were found to be equally effective in improving body weight and reducing length of hospital stay.Limitation. Long term follow-up was not taken.


2017 ◽  
Vol 32 (3) ◽  
pp. 729-735 ◽  
Author(s):  
Mariano Bacchi ◽  
Michelle F. Mottola ◽  
Maria Perales ◽  
Ignacio Refoyo ◽  
Ruben Barakat

Purpose: The aim of the present study was to examine the influence of a supervised and regular program of aquatic activities throughout gestation on maternal weight gain and birth weight. Design: A randomized clinical trial. Setting: Instituto de Obstetricia, Ginecología y Fertilidad Ghisoni (Buenos Aires, Argentina). Participants: One hundred eleven pregnant women were analyzed (31.6 ± 3.8 years). All women had uncomplicated and singleton pregnancies; 49 were allocated to the exercise group (EG) and 62 to the control group (CG). Intervention: The intervention program consisted of 3 weekly sessions of aerobic and resistance aquatic activities from weeks 10 to 12 until weeks 38 to 39 of gestation. Measures: Maternal weight gain, birth weight, and other maternal and fetal outcomes were obtained by hospital records. Analysis: Student unpaired t test and χ2 test were used; P values ≤.05 indicated statistical significance. Cohen’s d was used to determinate the effect size. Results: There was a higher percentage of women with excessive maternal weight gain in the CG (45.2%; n = 28) than in the EG (24.5%; n = 12; odds ratio = 0.39; 95% confidence interval: 0.17-0.89; P = .02). Birth weight and other pregnancy outcomes showed no differences between groups. Conclusion: Three weekly sessions of water activities throughout pregnancy prevents excessive maternal weight gain and preserves birth weight. Trial Registration: The clinicaltrial.gov identifier: NCT 02602106.


2020 ◽  
Vol 4 (3) ◽  
pp. 10-19
Author(s):  
I Made Samitha Wijaya ◽  
Made Sukmawati ◽  
Putu Junara Putra ◽  
I Made Kardana ◽  
I Wayan Dharma Artana

The purpose of this study was to determine the nutritional status of preterm neonates when discharged from the hospital. A descriptive study was reviewed from the register of preterm neonate after hospitalization in neonatal ward Sanglah Hospital Denpasar. The number of total samples in this study was 190 patients. Most of the preterm neonates in this study were low birth weight (59.47%). At the beginning of the hospitalization, there were 83.86% preterm neonates with good nutritional status, decreased to 54.73% at discharge from the hospital. The group of neonates that had the highest number of decreases in the good nutritional status at discharge was found in 28-32 weeks gestational age. Most of the samples used breast milk for enteral feeding (68,42%). In preterm neonates with sepsis, only 42.52% neonates discharge with good nutritional status. Low birth weight preterm neonates with kangaroo method care were found increased weight gain in 78.57% neonates. The nutritional status of preterm neonates following hospitalization at Sanglah hospital is still not good. The preterm neonates with good nutritional status were decreased at discharge from the hospital.


2018 ◽  
Author(s):  
Dwi Nur Octaviani Katili

THE EFFECT OF INFANT MASSAGE STIMULATION TOWARDS THE WEIGHT GAIN ON INFANTS WITH LOW BIRTH WEIGHT IN YOGYAKARTADwi Nur Octaviani Katili1, Djaswadi Dasuki2, Retno Mawarti3Universitas Muhammadiyah GorontaloEmail: [email protected]: Infants with low birth weight (LBW) require more nutrients inputs in order to optimize their growth and development. The increase of infants weight is used as the best indicator to determine the growth of infants with LBW. The massage on infant with LBW is a form of stimulus/kinesthetic tactile stimulation as a verbal communication to the infants. It can increase endurance, the activity of the digestive function, and the activity of the vagus nerve.Objective: To determine the benefits of infant massage stimulation as an effective non-medical way in gaining body weight on infants with low birth weight (LBW).Methods: The design of the study is Randomized Controlled Trial. The sampling technique is concecutive sample with the total samples are 15 respondents for each group (treatment and control). The data were analyzed with bivariate analysis stage by using independent t-test with a significance level of p value &lt;0.05 as well as multivariate analysisby using linear regression.Results: The t-test results showed that there is average difference in the gaining of body weight on infants with the low birth weight in the treatment and the control group as big as 53.67 grams with a p value &lt;0.001, 95% CI = -79.02 - (- 28.38).Conclusions: The weight gain on infants with low birth weight who do massage stimulation for 14 days is greater than infants who are not massaged.


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