scholarly journals Type ii osteoporosis pathogenesis as a result of secondary edentulous

2017 ◽  
Vol 16 (1) ◽  
pp. 127-137
Author(s):  
Bida Oleksiy ◽  
Bida Vitaliy ◽  
Kuzenko Yevhen ◽  
Diachenko Olena ◽  
Lyndin Mykola ◽  
...  
Keyword(s):  
Tooth Loss ◽  
Alveolar Bone ◽  
Morphological Changes ◽  
Histological Study ◽  
Medical Science ◽  
Oxygen Species ◽  
Type Ii ◽  
Biopsy Material ◽  
Atherosclerotic Lesions ◽  
Medical University

Purpose: The main sign of osteoporosis is a significant decrease of bone mass that is caused by imbalance between resorption and osteogenesis. There are two main factors that contribute to the genesis of this illness. All these factors bring todecrease of thickness of bone and its destruction doesn’t depend on their combination. Therefore, our objective was to study the changes in the alveolar bones of elderly people in secondary edentulous. Material and Methods: For deeper study of morphological changes in segments of teeth we have conducted pathological researches of biopsy material of dead patients at the Center of Pathological Studies of the Sumy Medical University. The first group of patients included n=7 who died of various somatic abnormalities and had no significant atherosclerotic lesions. The second group includes segments of teeth and jaws of patients n=7 who died from complications of atherosclerosis In our studies, we used: Histological study; Fluorescence microscopy; Immunohistochemistry; Microphotography and image analysis; Mathematical calculations. Results: Based on the statistical analysis we can see a downward trend in the number of osteocytes in trabeculae of the periapical third part of the tooth at atherosclerosis 26.85±7.44; P=0.05. We can also see the dependence of trabecular thinning of toothless area of the alveolar bone 226.57±70.53; P=0.02 from losing of teeth against the background of atherosclerosis with hypertension. The osteopontin expression and fluorescencetion of toothless bone area also tend to decrease in atherosclerosis and hypertension 42.81±16.24; P=0.048. Conclusion: The cause of tooth loss is difficult to determine, since it is not clear whether it is due to osteoporosis or some forms of periodontitis in patients. The bone resorption has actived by reactive oxygen species both during atherosclerosis. Through our research found out that in order to reduce changes in the toothless bone we should reduce the pressure on chewing toothless alveolar sprout by dental implants. Bangladesh Journal of Medical Science Vol.16(1) 2017 p.127-137

scholarly journals Dyspnea on swallowing: a case of thyroid lymphoma

2017 ◽  
Vol 16 (1) ◽  
pp. 138-141
Author(s):  
Basheer Lawal ◽  
Irfan Mohamad ◽  
Norzaliana Zawawi ◽  
Nor Hayati Othman ◽  
Azlan Husin
Keyword(s):  
Tooth Loss ◽  
Alveolar Bone ◽  
Morphological Changes ◽  
Histological Study ◽  
Medical Science ◽  
Oxygen Species ◽  
Thyroid Lymphoma ◽  
Biopsy Material ◽  
Atherosclerotic Lesions ◽  
Medical University

Purpose: The main sign of osteoporosis is a significant decrease of bone mass that is caused by imbalance between resorption and osteogenesis. There are two main factors that contribute to the genesis of this illness. All these factors bring todecrease of thickness of bone and its destruction doesn’t depend on their combination. Therefore, our objective was to study the changes in the alveolar bones of elderly people in secondary edentulous.Material and Methods: For deeper study of morphological changes in segments of teeth we have conducted pathological researches of biopsy material of dead patients at the Center of Pathological Studies of the Sumy Medical University. The first group of patients included n=7 who died of various somatic abnormalities and had no significant atherosclerotic lesions. The second group includes segments of teeth and jaws of patients n=7 who died from complications of atherosclerosis In our studies, we used: Histological study; Fluorescence microscopy; Immunohistochemistry; Microphotography and image analysis; Mathematical calculations.Results: Based on the statistical analysis we can see a downward trend in the number of osteocytes in trabeculae of the periapical third part of the tooth at atherosclerosis 26.85±7.44; P=0.05. We can also see the dependence of trabecular thinning of toothless area of the alveolar bone 226.57±70.53; P=0.02 from losing of teeth against the background of atherosclerosis with hypertension. The osteopontin expression and fluorescencetion of toothless bone area also tend to decrease in atherosclerosis and hypertension 42.81±16.24; P=0.048.Conclusion: The cause of tooth loss is difficult to determine, since it is not clear whether it is due to osteoporosis or some forms of periodontitis in patients. The bone resorption has actived by reactive oxygen species both during atherosclerosis. Through our research found out that in order to reduce changes in the toothless bone we should reduce the pressure on chewing toothless alveolar sprout by dental implants.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.138-141

EVALUATION OF LOWER WISDOM TEETH SURGERY RESULTS AT THAI BINH MEDICAL UNIVERSITY HOSPITAL

2021 ◽  
Vol 62 (5) ◽  
Author(s):  
Nguyen Thi Sen ◽  
Le Xuan Hung
Keyword(s):  
Tooth Extraction ◽  
Alveolar Bone ◽  
Objective Evaluation ◽  
University Hospital ◽  
Type Ii ◽  
Root Fracture ◽  
Wisdom Teeth ◽  
Medical University

Objective: Evaluation of lower wisdom teeth surgery results at Thai Binh Medical University Hospital.Subjects and methods: Progressive study on 143 subjects with lower wisdom teeth surgery at Thai Binh Medical University Hospital from November 2019 to June 2020.Results: Parant type II surgery accounted for the highest rate 44.76%. Surgery time from 30-60 minutes accounts for the majority of 48.25%. In the process of surgery, the most common accident isfracture/rupture of the bone in the lower wisdom teeth accounting for 57.34%, root fracture accounts for 11.89%, a case of mild late anesthetic allergy is recorded. Long-term bleeding complicationsaccounted for 11.19%; dry alveolar acupressure and wet alveolar acupressure accounted for 8.39% and 7.69% respectively.Conclusions: According to Parant dividing lower wisdom teeth surgery into 4 types, the rate of type II surgery, ie tooth extraction needs to open a part of the alveolar bone and cut the neck of the teethfor the majority.

scholarly journals Morphological changes of the anterior alveolar bone due to retraction of anterior teeth: a retrospective study

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Qiannan Sun ◽  
Wenhsuan Lu ◽  
Yunfan Zhang ◽  
Liying Peng ◽  
Si Chen ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
Alveolar Bone ◽  
Morphological Changes ◽  
Strong Positive Correlation ◽  
Anterior Teeth ◽  
Bone Width ◽  
Lateral Cephalograms ◽  
Labial Side ◽  
Incisor Retraction ◽  
Maxilla And Mandible

Abstract Backgroud To analyze the morphological changes of the anterior alveolar bone after the retraction of incisors in premolar extraction cases and the relationship between incisor retraction and remodeling of the alveolar base represented by points A and B displacements. Methods Pre- (T0) and post-treatment (T1) lateral cephalograms of 308 subjects in the maxilla and 154 subjects in the mandible who underwent the orthodontic treatment with extraction of 2 premolars in upper or lower arches were included. Alveolar bone width and height in both the maxillary and mandible incisor area were measured at T0 and T1 respectively. By superimposing the T0 and T1 cephalometric tracings, changes of points A and B, and the movement of the incisors were also measured. Then the correlation between incisor movement and the displacements of points A and B was analyzed. Results The alveolar bone width (ABW) showed a significant decrease in both maxilla and mandible (P < 0.001) except the labial side of the mandible (P > 0.05). The alveolar bone height (ABH) showed a significant increase in the labial side of maxilla and a significant decrease in the lingual side of maxilla and mandible. A strong positive correlation was verified between incisor movement and position changes of points A and B in both horizontal and vertical directions. Conclusions Anterior alveolar bone width and height generally decreased after orthodontic treatment. Incisor retraction led to significant position changes of points A and B. The decrease of anterior alveolar bone due to significant incisor retraction should be taken into account in treatment planning.

Effects of Aging on Type II Muscle Fibers: A Systematic Review of the Literature

2007 ◽  
Vol 15 (3) ◽  
pp. 336-348 ◽  
Author(s):  
Florian Brunner ◽  
Annina Schmid ◽  
Ali Sheikhzadeh ◽  
Margareta Nordin ◽  
Jangwhon Yoon ◽  
...  
Keyword(s):  
Systematic Review ◽  
Skeletal Muscles ◽  
Morphological Changes ◽  
Fiber Type ◽  
Muscle Fibers ◽  
Type Ii ◽  
Review Of The Literature ◽  
Effects Of Aging ◽  
Complex Phenomena ◽  
Human Skeletal Muscles

The authors conducted a systematic review of the literature for scientific articles in selected databases to determine the effects of aging on Type II muscle fibers in human skeletal muscles. They found that aging of Type II muscle fibers is primarily associated with a loss of fibers and a decrease in fiber size. Morphological changes with increasing age particularly included Type II fiber grouping. There is conflicting evidence regarding the change of proportion of Type II fibers. Type II muscle fibers seem to play an important role in the aging process of human skeletal muscles. According to this literature review, loss of fibers, decrease in size, and fiber-type grouping represent major quantitative changes. Because the process of aging involves various complex phenomena such as fiber-type coexpression, however, it seems difficult to assign those changes solely to a specific fiber type.

Cerium oxide nanozyme attenuates periodontal bone destruction by inhibiting ROS-NFκB pathway

Nanoscale ◽  
2022 ◽  
Author(s):  
Yijun Yu ◽  
Sheng Zhao ◽  
Deao Gu ◽  
Bijun Zhu ◽  
Hanxiao Liu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Bone Resorption ◽  
Inflammatory Disease ◽  
Tissue Damage ◽  
Alveolar Bone ◽  
Bone Destruction ◽  
Oxygen Species ◽  
Nfκb Pathway ◽  
Excess Reactive Oxygen Species

Periodontitis, an inflammatory disease of oxidative stress, occurs due to the excess reactive oxygen species (ROS) contributing to cell and tissue damage that in turn leads to alveolar bone resorption...

scholarly journals EFFECT OF ORAL AZITHROMYCIN AND METRONIDAZOLE AS AN ADJUNCT TO SCALING AND ROOT PLANING ON GLYCEMIC CONTROL IN TYPE II DIABETIC PATIENTS WITH CHRONIC PERIODONTITIS

2017 ◽  
Vol 10 (3) ◽  
pp. 449
Author(s):  
Dhivya K ◽  
Yogarajan K ◽  
Shanmugarajan T S
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Chronic Periodontitis ◽  
Alveolar Bone ◽  
Tertiary Care ◽  
Periodontal Therapy ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Type Ii ◽  
Oral Azithromycin

ABSTRACTObjective: Periodontitis, a chronic inflammatory disease characterized by destruction of the periodontal ligament and alveolar bone is the sixthcomplication of diabetes mellitus. Periodontal treatment that reduces gingival inflammation aids in the control of hyperglycemia. Therefore, thepresent study was designed to determine the effect of treating chronic periodontitis with oral antibiotics azithromycin and metronidazole on the levelof serum glycated hemoglobin in type-II diabetic patients.Methods: This prospective observational study was carried out in the dental department of a tertiary care hospital for 9 months. Clinical andbiochemistry reports of 90 patients were collected in designed case report forms. All statistical analyses were performed using IBM Statistical Packagefor Social Sciences 17 and Graph Pad Prism 7.0.Results: Significant reduction in all the clinical and dental parameters was comparatively higher in patients who received azithromycin than inpatients who received metronidazole and scaling and root planning alone.Conclusion: Periodontal therapy with oral azithromycin can be employed as a supportive strategy for the management of diabetes mellitus.Henceforth, prevention and control of periodontal disease along with antibiotics must be considered an integral part of glycemic control. However,due to the lesser sample size in this study, further investigations are required to confirm the effect of periodontal therapy on systemic diseases.Keywords: Periodontitis, Azithromycin, Metronidazole, Glycemic control, Diabetes mellitus.

scholarly journals Photodynamic Effect of 5,10,15,20-Tetrakis[4-(3-N,N-dimethylaminopropoxy)phenyl]chlorin towards the Human Pathogen Candida albicans under Different Culture Conditions

Photochem ◽  
2021 ◽  
Vol 1 (3) ◽  
pp. 505-522
Author(s):  
Paula V. Cordero ◽  
Darío D. Ferreyra ◽  
María E. Pérez ◽  
María G. Alvarez ◽  
Edgardo N. Durantini
Keyword(s):  
Candida Albicans ◽  
Culture Conditions ◽  
Oxygen Species ◽  
Type Ii ◽  
Planktonic Cells ◽  
Quenching Rate ◽  
Log Reduction ◽  
Quenching Rate Constant ◽  
Bimolecular Quenching ◽  
Human Pathogen Candida Albicans

Photocytotoxic activity sensitized by 5,10,15,20-tetrakis[4-(3-N,N-dimethylaminopropoxy)phenyl]chlorin (TAPC) was investigated in Candida albicans under different culture conditions. Planktonic cells incubated with 2.5 μM TAPC were eradicated after 5 min irradiation with white light. Studies in the presence of reactive oxygen species scavengers indicated the involvement of mainly a type II mechanism. Furthermore, cell growth of C. albicans was suppressed in the presence of 5 μM TAPC. A decrease in pseudohyphae survival of 5 log was found after 30 min irradiation. However, the photokilling of this virulence factor reached a 1.5 log reduction in human serum. The uptake of TAPC by pseudohyphae decreased in serum due to the interaction of TAPC with albumin. The binding constant of the TAPC-albumin complex was ~104 M−1, while the bimolecular quenching rate constant was ~1012 s−1 M−1, indicating that this process occurred through a static process. Thus, the photoinactivation of C. albicans was considerably decreased in the presence of albumin. A reduction of 2 log in cell survival was observed using 4.5% albumin and 30 min irradiation. The results allow optimizing the best conditions to inactivate C. albicans under different culture conditions.

scholarly journals DIAGNOSTIC VALUE OF MORPHOLOGICAL CHANGES IN GASTROESOPHAGEAL REFLUX DISEASE IN BIOPSY MATERIAL OF THE DISTAL ESOPHAGUS IN ADOLESCENTS SICKLY WITH ACUTE RESPIRATORY DISEASES

2019 ◽  
Vol 1 ◽  
pp. 15-23
Author(s):  
Olena Zhuravel ◽  
Tetyana Pochinok ◽  
Tamara Zadorozhna ◽  
Tetyana Archakova ◽  
Valentyna Zamula
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Mucous Membrane ◽  
Reflux Disease ◽  
Respiratory Diseases ◽  
Morphological Changes ◽  
Diagnostic Value ◽  
Distal Esophagus ◽  
Biopsy Material ◽  
Acute Respiratory Diseases

The article dedicated to the problem of the diagnostic value of morphological changes in gastroesophageal reflux disease in the biopsy of the distal esophagus in pubertal children of childbearing age. Aim of the research is to investigate the diagnostic value of morphological changes in gastroesophageal reflux disease in esophageal biopsy material in adolescents sickly with acute respiratory diseases. Methodology. The objective of the study was achieved through examination of 90 adolescents (10 to 16 years old, average age 13.1±3.54 years) kept under observation at the Children’s Clinical Hospital No. 9 of Kyiv and on the basis of the Department of Pediatrics No. 1 Center of Primary Health Care No. 4 of the Desnianskyi district of Kyiv. All adolescents belonged to the group of sickly with a number of respiratory diseases averaging 6-8 times a year, lasting from 8 to 18 days (on average 12.8±5.41 days). All children have undergone endoscopic examination of the esophagus, stomach and duodenum with the esophagus mucosa biopsy using the OLYMPUS GIF-P3 flexible fiberscope. Results. It was found that the least valuable diagnostic feature in the morphological examination of the mucous membrane of the distal esophagus in the pain-causing children with GERD was thickening of the epithelium with a sensitivity of 13,0 %, a specificity of 96.0 %, and total value of 65.0 %. It has been proved that hyperplasia of cells of the basal layer of the mucous membrane of the distal esophagus at the GERD in the infected children is 46.7 % (specificity – 93.3 %, the total value is 75.6 %). Increase in the number of papillae and their prolongation in 33.3 % cases (sensitivity – 33.3 %, specificity – 93.3 %, overall diagnostic value – 70.8 %). Conclusion. The peculiarity of the morphological manifestations of GERD in childbearing children is dystrophic changes in keratocytes in the superficial parts of the multilayer squamous epithelium, which are detected at 100.0 % of patients (specificity is 93.3 %, total value is 96.8 %), with parakeratosis centers at 13.3 % of cases. It has been shown that a frequent and diagnostically valuable indication is inflammatory infiltration of the esophageal mucosa, which are verified in all cases (100.0 %, with dilatation and hyperemia in 46.7 % of patients (specificity – 40.0 %, total value – 81.3 %).

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