scholarly journals Perinatal factors among children with neurodevelopmental disorders attending tertiary care hospitals in Dhaka city

2020 ◽  
Vol 32 (2) ◽  
pp. 26-31
Author(s):  
Fatima Zohra ◽  
Md Faruq Alam ◽  
Mekhala Sarkar ◽  
Shahriar Faruque ◽  
Mohammad Waliul Hasnat Sajib
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Neurodevelopmental Disorders ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Dhaka City ◽  
Perinatal Factors ◽  
Public Health Burden ◽  
Tertiary Care Hospitals

Neurodevelopmental disorders (NDD) are public health burden worldwide. NDD causes disabilities and reduces the quality of life. Perinatal factors like maternal age, stress, maternal physical illnesses, birth complications, preterm birth, low birth weight and neonatal infections are the important risk factors for NDD. The objectives of the study were to determine the proportion of perinatal factors among children with neurodevelopmental disorders attending tertiary care hospitals in Dhaka city. This was a cross-sectional study conducted in outpatient department of National Institute of Mental Health (NIMH), Dhaka and Institute of Paediatric Neurodisorder and Autism (IPNA), Bangabandhu Sheikh Mujib Medical University (BSMMU) from January 2017 to July 2018. Among 115 children with NDD aged 0-17 years satisfying inclusion and exclusion criteria who were conveniently selected as sample. After diagnosing NDD using DSM- 5 criteria by psychiatrists and paediatric neurologists, a semi structured questionnaire was applied by researcher herself that included socio-demographic and perinatal factors as well. Results showed that majority of the respondents (29.6%) were 5-8 years with male predominance (78.3%). The most common perinatal factors were maternal factors like maternal stress (68.7%), maternal physical illness (66.1 %), inadequate food/rest intake (53.9%) and inadequate weight gain during pregnancy (50.4%). Fetal and neonatal factors like birth complication (82.6%), preterm birth (80%), low birth weight (75.6%), neonatal illness (69.6%) and birth asphyxia (61.7%). Most common neonatal illness were pneumonia (30.0 %) followed by neonatal Jaundice (20%). Early identification of possible perinatal factors and providing safe perinatal period can give a positive impact in prevention of NDD in children. Bang J Psychiatry 2018;32(2): 26-31

scholarly journals A profile on the spectrum of neonatal mortality and morbidity pattern of extramural neonates in the Specialised Neonatal Care Unit (SNCU) in a tertiary care hospital

2018 ◽  
Vol 5 (2) ◽  
pp. 427 ◽  
Author(s):  
Anuradha D. ◽  
Rajesh Kumar S. ◽  
Aravind M. A. ◽  
Jayakumar M. ◽  
J. Ganesh J.
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Respiratory Distress ◽  
Neonatal Mortality ◽  
Low Birthweight ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Newborn Care ◽  
Care Hospital ◽  
Neonatal Deaths

Background: Every year, nearly four million newborn babies die in the first month of life. India carries the single largest share (around 25-30%) of neonatal deaths in the world. Neonatal deaths constitute two thirds of infant deaths in India. 45% of the deaths occur within the first two days of life. It has been estimated that about 70% of neonatal deaths could be prevented if proven interventions are implemented effectively at the appropriate time. It was further estimated that health facility-based interventions can reduce neonatal mortality by 23-50% in different settings. Facility-based newborn care, thus, has a significant potential for improving the survival of newborns in India. This research has been planned with an aim to study the profile of pattern of admissions in a SNCU and their outcomes following admission and management in the unit.Methods: All babies referred for neonatal problems (less than 28 days) and admitted in NICU will be included. Both term and preterm babies will be considered. The criteria for admission includes various causes like low birth weight, preterm, birth asphyxia, respiratory distress, hyperbilirubinemia, congenital anomalies, risk factors (maternal, neonatal, prenatal), infections and outcome will be analysed.Results: Among the 2927 admissions term babies and boys outnumbered. The common causes for admission were birth asphyxia, respiratory distress, low birthweight and preterm. Most babies had an uncomplicated stay. The mortality in the extramural neonates was due to neonatal sepsis, extreme preterm and congenital malformations.Conclusions: Intensive and interventional management, along with good neonatal monitoring and care can reduce the mortality and improve the survival of low birth weight babies and other treatable problems. Thus, a combined effort of management by pediatricians, nursing care, neonatal intensive care unit can improve the survival rates of neonates.

scholarly journals An Analysis of Five years Neonatal Mortality in NICU of a Tertiary Care Hospital of Rawalpindi 2014-2019

2020 ◽  
Vol 24 (4) ◽  
pp. 328-333
Author(s):  
Rai Muhammad Asghar ◽  
Muddasir Sharif ◽  
Khalid Saheel ◽  
Rai Rijjal Ashraf ◽  
Abid Hussain
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Mortality ◽  
Neonatal Jaundice ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Meconium Aspiration Syndrome ◽  
Care Hospital ◽  
Female Ratio ◽  
Meconium Aspiration

Objective: This study was done to find out the main causes and magnitude of neonatal mortality in the neonatal intensive care unit (NICU) of Benazir Bhutto Hospital, Rawalpindi over a period of five years.Material and Methods: A hospital-based cross-sectional study was done from June 2014 to July 2019. The registration book of admitted neonates was reviewed by using a checklist to collect data. Data was analyzed in SPSS 24 for descriptive and bi-variate analysis applying the chi-square test and presented in text, frequencies, tables, and percentages.Results: The study assessed a total of 24,459 neonates admitted to the NICU at Benazir Bhutto Hospital over a span of five years (June 2014 to July 2019). The mean birth weight was 2432 grams ± 740 g (range: Between 800 and 6000 g). Male neonates accounted for 59.8% with male to female ratio of 1.5:1. 67.5% male neonates and 32.5% female neonates expired. Overall 19,832 neonates (81.1%) were discharged, while 4636 (18.9%) died, making a Neonatal Mortality Rate of 18.9% (189 per 1000 admissions). 86.21% of these deaths were early neonatal that occurred in the first week of life. The causes of death were pre-maturity/ low birth weight (LBW), suspected sepsis, birth asphyxia, neonatal jaundice, and meconium aspiration syndrome, accounting for 32%, 31%, 30%, 4%, and 3% respectively.Conclusion: In our NICU the neonatal mortality is high with prematurity/low birth weight (LBW), birth asphyxia (BA), neonatal jaundice (NNJ), and meconium aspiration syndrome (MAS) accounting for most of the deaths. These deaths are largely preventable with better antenatal, perinatal, and neonatal care.

scholarly journals Immediate Outcome of Vlbw And Elbw Babies in a Tertiary Care Center of Nepal

2015 ◽  
Vol 12 (1) ◽  
pp. 32-34
Author(s):  
N Acharya ◽  
P Mishra ◽  
N Shrestha ◽  
V Gupta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Care Center ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Extremely Low Birth Weight ◽  
Mechanical Ventilators ◽  
Medical College ◽  
Trained Staff

Background: Very Low Birth Weight (VLBW) infants weigh <1500 grams and Extremely Low Birth Weight (ELBW) infants weigh <1000 grams. They are predominantly premature but may also be associated with Intrauterine Growth Restriction (IUGR). The VLBW rate is an accurate predictor of infant mortality rate.Objective: The study was aimed to find out the hospital incidence of VLBW and ELBW babies and outcome of these babies, till they were discharged from the hospital/NICU.Methods: A descriptive study was conducted among 109 cases who weighed less than 1500 grams. The babies were evaluated for mortality and various morbidities till they were discharged from the hospital. Descriptive statistics was applied using SPSS 21.0 to show antenatal profile and immediate outcome. Results: Out of 109 cases, ELBW were 30.2% and VLBW were 69.8%. Among the ELBW babies, 30.3% survived and 75% in VLBW. The mortality rate in ELBW and VLBW babies were 69.7% and 25% respectively. Among the ELBW, common morbidities were NNJ (94%), Presumed NNS (87.8%), RDS (82.6%), Hypoglycemia (56.5%), Hypothermia (26%), Birth Asphyxia (15.1%). In the VLBW group, common morbidities were Presumed NNS (86.4%), NNJ (82%), RDS (46.5%), Hypoglycemia (30.2%). The mean duration of hospital stay was 8.6 days (SD ± 3.38).Conclusions: Common immediate morbidities were NNS, RDS, Hypothermia, Anemia, Shock, CHD, Birth Asphyxia and NEC. Well trained staff in the NICU and medical facilities like availability of Surfactant therapy, more number of mechanical ventilators could improve the survival of these babies in our setting.Journal of Nepalgunj Medical College Vol.12(1) 2014: 32-34

scholarly journals Prevalence and Risk Factors of Perinatal Asphyxia in a Tertiary Care Level Hospital, Harari Regional State, Ethiopia

2019 ◽  
Vol 39 (2) ◽  
pp. 103-108
Author(s):  
Arif Hussen Jamie ◽  
Mohammed Z Abdosh
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Perinatal Asphyxia ◽  
Tertiary Care ◽  
Multivariate Logistic Regression Analysis ◽  
Birth Asphyxia ◽  
Chronic Hypertension ◽  
Early Screening ◽  
Cross Sectional ◽  
Level Hospital

Introduction: Globally birth asphyxia continues to present a major clinical problem. It is one of the common and leading causes of perinatal and neonatal mortality and morbidity especially in developing countries. Methods: A cross-sectional study was conducted among newborns in a tertiary level hospital, Ethiopia from February to July 2019. Systematic random sampling technique was used to select the study subjects. Multivariate logistic regression analysis was used to identify factors associated with the perinatal asphyxia among newborns. Results: Of the newborns, 32% had perinatal asphyxia and factors significantly associated were anaemia during pregnancy (adjusted OR = 2.99, 95% CI: 1.07 – 8.35), chronic hypertension (adjusted OR = 4.89, 95% CI: 1.16 – 20.72) and low birth weight newborns (adjusted OR = 3.31, 95% CI: 1.308 – 8.37). Conclusions: Maternal anaemia during pregnancy, chronic hypertension and low birth weight were significantly associated with perinatal asphyxia. Therefore, early screening and appropriate intervention during pregnancy and intra-partum might reduce perinatal asphyxia among newborns.

scholarly journals Evaluation of Maternal and Perinatal Outcome in Pregnancy with Jaundice in a Tertiary Care Hospital

2021 ◽  
Vol 10 (36) ◽  
pp. 3099-3102
Author(s):  
Mihir Kumar Sarkar ◽  
Arindam Halder
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Viral Hepatitis ◽  
Postpartum Haemorrhage ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Birth Asphyxia ◽  
Intrauterine Fetal Death ◽  
Care Hospital ◽  
In Pregnancy

BACKGROUND Jaundice in pregnancy contributes to a significant proportion of maternal and perinatal morbidity and mortality in our country. Overall incidence in India is 1 - 4 per 1000 deliveries. There are increased risks of preterm labour, low birth weight babies, meconium-stained liquor, intrauterine fetal death and postpartum haemorrhage. The purpose of this study was to assess the fetomaternal outcome in pregnancy with jaundice in a tertiary level hospital. METHODS This was a two-year retrospective observational study conducted by reviewing the records of jaundice in pregnancy from April 2018 to March 2020. RESULTS Viral hepatitis comes out as the most common cause accounting for 70.37 % of the cases, whereas intrahepatic cholestasis with an incidence of 20. 37 % comes out as the second aetiology. Post-partum haemorrhage is depicted as the major maternal complication whereas prematurity and birth asphyxia come out as the major perinatal complications. CONCLUSIONS The present study projects viral hepatitis (Hepatitis A and E) as the major cause of jaundice in pregnancy. Although low maternal mortality has been recorded in the present study, a high perinatal mortality due to low birth weight and birth asphyxia remains to be a matter of major concern. KEY WORDS Jaundice in Pregnancy, Viral Hepatitis, Postpartum Haemorrhage, Prematurity, Birth Asphyxia

scholarly journals A Longitudinal Analysis of the Mortality Spectrum of Children under 5 Years from 1990 to 2015 in Hubei Province of China

2017 ◽  
Vol 9 (9) ◽  
pp. 138
Author(s):  
Zhonggui Xiong ◽  
Yusong Xu ◽  
Xiangdong Li ◽  
Junxin Shi
Keyword(s):  
Health Care ◽  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Care Service ◽  
Health Care Service ◽  
Birth Asphyxia ◽  
Hubei Province ◽  
District Hospitals ◽  
Children Under 5

OBJECTIVES: This research analyzed trends of the mortality spectrum resulted from dynamics of the health care service for children under 5 years.METHODS: It was sampled 23 surveillance sites to establish a population-based surveillance network for children under 5 years by implementing a multistage randomized, stratified and cluster sampling since 1990 in Hubei province of China.RESULTS: Among children under 5 years, the mortality rates of pneumonia, birth asphyxia, preterm birth/low birth weight and accidental asphyxia declined from 12.9, 6.6, 4.3 and 3.5 in 1990 to 0.9, 0.7, 1.1 and 0.7 per 1,000 live births in 2015 respectively, and manifested a distinguished milestone at which pneumonia and birth asphyxia had been replaced by preterm birth/low birth weight after 2005 (P&lt;0.05). The death proportions of pneumonia and birth asphyxia decreased from 22.2% and 11.4% in 1990 to 10.3% and 7.7% in 2015, while the death proportions of preterm birth/low birth weight and accidental asphyxia increased from 7.4% and 6.0 % in 1990 to 12.9% and 8.6% in 2015 accordingly. The proportions of clinical diagnosis, emergence treatment and death place at the county/district hospitals increased from 9.0%, 27.4% and 28.7% in 1990 to 75.5%, 67.7% and 60.4% in 2015, and had the significant differences between 1990 and 2015 in Hubei province (P&lt;0.01).CONCLUSIONS: It was suggested that the trends of the mortality spectrum were mainly due to the improvement of the health care service for children under 5 years in Hubei province.

scholarly journals Morbidity and mortality profile of neonates in a tertiary care centre in Tamil Nadu: a study from South India

2018 ◽  
Vol 5 (2) ◽  
pp. 377 ◽  
Author(s):  
Ravikumar S. A. ◽  
Harikrishnan Elangovan ◽  
Elayaraja K. ◽  
Aravind Sunderavel K. K.
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Tamil Nadu ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Morbidity And Mortality ◽  
Normal Birth Weight ◽  
Mortality Pattern ◽  
Normal Birth ◽  
Significant Difference

Background: Accurate data on morbidity and mortality pattern are useful for many reasons. The Perinatal and the neonatal period are so short but they are the most critical faces of human life1. It reflects the general health and the socio-biological features of the most vulnerable groups of the society, the mothers and the infants. The objectives of this study was to investigate the morbidity and mortality pattern of neonates admitted in Neonatal Intensive Care Unit (NICU) of tertiary care hospital.Methods: All the neonates admitted to NICU from July 2013 to June 2015, excluding the neonates referred and discharged against medical advice were retrospectively analysed for demographic profile, short term morbidity and outcome.Results: 3118 neonates were admitted in the study period. 57.5% were Males, 72.5% were inborn, 69% were term babies and 53.3% had normal birth weight. Important causes for morbidity were Perinatal asphyxia 490 (15.7%), Preterm/LBW 456 (14.6%), Neonatal jaundice 438 (14%) and then sepsis 402 (12.9%). The mortality rate was 10.4% with statistical significant difference between inborn and outborn babies (P<0.0001). The major causes of mortality are Respiratory syndrome 109 (33.6%), followed by birth asphyxia 82 (25.3%) and sepsis 82 (25.3%). The survival of term as well as normal birth weight babies was statistically significant over preterm (P<0.0001) and Low Birth Weight (LBW), Very Low Birth Weight (VLBW), Extreme Low Birth Weight (ELBW) neonates (P<0.0001> respectively.Conclusions: Birth asphyxia, prematurity, Jaundice and neonatal sepsis respiratory problems were major causes of both mortality and morbidity. There is need to strengthen services to address these problems more effectively. 

scholarly journals Maternal and Neonatal Outcomes of Syrian Adolescent Refugees and Local Adolescent Turkish Citizens: A Comparative Study at a Tertiary Care Maternity Hospital in Turkey

2021 ◽  
pp. 1-9
Author(s):  
Ceren Golbasi ◽  
Tayfun Vural ◽  
Burak Bayraktar ◽  
Hakan Golbasi ◽  
Alkim Gulsah Sahingoz Yildirim
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Screening Test ◽  
Tertiary Care ◽  
Obstetric Outcomes ◽  
Syrian Refugees ◽  
Average Birth Weight ◽  
Adolescent Refugees

OBJECTIVE: In this study, we aim to compare the maternal and obstetric outcomes between local adolescent Turkish citizens and adolescent Syrian refugees admitted to a tertiary care center in Turkey. STUDY DESIGN: Between January 2014 and December 2019, a total of 57,049 births were performed in our hospital. The study included a total of 6,021 patients aged 19 years or younger pregnancy who gave birth at our hospital. Of this number, 5,164 (1,792 Syrian adolescent refugee cases and 3,372 local adolescent Turkish cases) were live singleton pregnancies. Our primary aim was to compare the maternal and obstetric outcomes between the two groups. RESULTS: In the pregnant refugee women, the maternal age was younger (p<0.001). Hemoglobin and hematocrit levels are significantly lower in Syrian pregnant women (p<0.001 and p<0.001, respectively). Anemia was significantly higher in Syrian refugee pregnant women (p<0.001). The double screening test and triple screening test were significantly lower in Syrian pregnant women (p<0.001 and p<0.001, respectively). Preterm birth rates and late preterm delivery prevalence (34-37 gestational weeks) were significantly higher in the adolescent Syrian immigrants' compared to the adolescent Turkish locals (p<0.001 and p<0.001, respectively). The average birth weight of the Syrian refugees was lower but the number of low birth weight babies was higher Turkish locals (p=0.010 and p=0.014, respectively). The preterm birth ratio and low birth weight ratio in Syrian adolescents has decreased over the years. CONCLUSION: Syrian adolescent refugees are particularly at risk of early pregnancy, high fertility rate, preterm birth, low birth weight, and anemia. Immigrant women should be provided with fertility, family planning, and training on behavior that protects reproductive health. Syrian pregnant women should be supported to receive services.

Advanced Maternal Age and Adverse Maternal and Neonatal Outcomes in Pregnant Women

2020 ◽  
Vol 16 ◽  
Author(s):  
Reza Omani-Samani ◽  
Saman Maroufizadeh ◽  
Nafise Saedi ◽  
Nasim Shokouhi ◽  
Arezoo Esmailzadeh ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Pregnant Women ◽  
Maternal Age ◽  
Unwanted Pregnancy ◽  
Advanced Maternal Age ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes

Background: Advanced maternal age is an important predictor for maternal and neonatal outcomes such as maternal mortality, low birth weight, stillbirth, preterm birth, cesarean section and preeclampsia. Objective: To determine the association of advanced maternal age and adverse maternal and neonatal outcomes in Iranian pregnant women. Methods: In this hospital-based cross-sectional study, 5117 pregnant women from 103 hospitals in Tehran, Iran, were participated in the study in 2015. The required data were gathered from hospitals which equipped to the department of obstetrics and gynecology. Advanced maternal age was considered as an independent variable and unwanted pregnancy, preeclampsia, preterm birth, cesarean section and low birth weight were considered as interested outcomes. Results: In our study, the prevalence of advanced maternal age was 12.08%. Advanced maternal age was significantly associated with higher risk of unwanted pregnancy (OR: 1.39, 95% CI: 1.12-1.73), preterm birth (OR: 1.75, 95% CI: 1.28- 2.39) and cesarean section (OR: 1.34, 95% CI: 1.03-1.74). In our study, there was no significant relationship between advanced maternal age and preeclampsia but this relationship could be clinically important (OR: 1.48, 95% CI: 0.99-2.20, P=0.052), and there is no significant relationship between advanced maternal age and low birth weight (OR: 1.08, 95% CI: 0.67-1.74, P=0.736). Conclusion: Advanced maternal age is associated with higher risk of unintended pregnancy, preterm birth and cesarean section but our findings did not support advanced maternal age as a risk factor associated with low birth weight.

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