scholarly journals A Study on Efficacy of Oral Itraconazole in the Treatment of Seborrheic Dermatitis

2021 ◽  
Vol 16 (1) ◽  
pp. 21-24
Author(s):  
Sahadev Kumar Adhikary ◽  
Md Eakub Ali ◽  
Md Jamal Uddin ◽  
Shireen Akter ◽  
Masood Mohammad Abdul Aziz ◽  
...  
Keyword(s):  
Chronic Disease ◽  
Initial Treatment ◽  
Blood Test ◽  
Antifungal Agents ◽  
Seborrheic Dermatitis ◽  
Burning Sensation ◽  
Clinical Parameters ◽  
Direct Smear ◽  
Common Chronic Disease ◽  
Oral Itraconazole

Seborrheic dermatitis is a common chronic disease. Malassezia yeasts have been implicated in the pathogenesis of this disease. Antifungal agents are known to be effective in the treatment of Malassezia yeast infections. This study was done to evaluate the efficacy of itraconazole in the treatment of seborrheic dermatitis. Sixty patients with Seborrheic dermatitis were evaluated in an open non-comparative study. Patients were treated with itraconazole capsule 100 mg twice a day for a week; then after a 3-week interval 100 mg capsule was given twice a day for 2 days of following months for two consecutive months. Four clinical parameters (Itching, burning erythema, scaling, and seborrhea) were assessed using a 0 to 3-point (0= absent, 1 = mild, 2 = moderate, 3 = severe) score. Mycological evaluation determined the presence of Malassezia spores in the scales using a direct smear. At the end of the initial treatment significant improvement was reported in four clinical parameters: Itching, burning erythema, scaling, and seborrhea. Maintenance therapy led to further improvement slightly. Burning sensation mildly improved during the treatment. The quantity of Malassezia spores present in the direct smear decreased throughout the treatment period. Blood test abnormalities were not found during the treatment. So initial treatment with itraconazole is beneficial in patients with seborrheic dermatitis. Faridpur Med. Coll. J. 2021;16(1):21-24

Blood Analysis Requests of Patients’ and Clinical Reflections in Primary Care

2020 ◽  
Vol 9 (2) ◽  
pp. 96-102
Author(s):  
Zerrin Gamsizkan ◽  
Mehmet Ali Sungur ◽  
Yasemin Çayır
Keyword(s):  
Chronic Disease ◽  
Blood Test ◽  
Family Health ◽  
Cross Sectional Study ◽  
Blood Analysis ◽  
Primary Role ◽  
Cross Sectional ◽  
High Expectations ◽  
Blood Tests ◽  
Study Results

Aim: The aim of the study is to determine the factors that may affect the demands of patients who come with the request to have a blood test without any chronic disease or a planned examination check. Methods: The data of this descriptive, cross-sectional study, were collected with a questionnaire that was prepared to examine the opinions of the patients who claim to have a blood test by coming to the family health center without any complaints. Patients over 18 years of age, who did not have any chronic disease and had no scheduled examination appointments were included in the study. Results: A total of 278 patients who wanted to have a blood test within the 6-months period were included in the study. Female patients who wanted to have a blood test were significantly more than male patients. When we look at the causes of patients who wanted to have a blood test; 61.2% (n=170) patients stated that they are concerned about their health and 6.1% (n=17) stated that they were affected by media warnings. There was no significant relationship between the frequency of blood test requests of patients and their age, gender, education, and general health status. Conclusion: Patients with high expectations and anxiety may be more willing to perform blood tests at inappropriate intervals. Family physicians, whose primary role is preventive medicine, have consultancy and information duties in order to protect their patients from the risk of over-examination and diagnosis. Keywords: blood tests, patient, screening, routine diagnostic tests

scholarly journals Immunity and its role in periodontal diseases

2017 ◽  
Vol 63 (1) ◽  
pp. 24-27
Author(s):  
Irina Dumitrache ◽  
Keyword(s):  
Immune Response ◽  
Chronic Disease ◽  
Periodontal Disease ◽  
Clinical Efficacy ◽  
Periodontal Diseases ◽  
Adult Population ◽  
Host Immune Response ◽  
Immunomodulatory Therapy ◽  
Common Chronic Disease

Periodontal disease is one of the most common chronic disease, with a prevalence between 5% and 30% in adult population aged 25-75. In the pathogenesis of periodontal disease, the host immune response has a great importance and in the last years it has been underlined the role of immunomodulatory therapy in the management of periodontal disease. Septilin is a herbal immunomodulatory with clinical efficacy proven in the periodontal disease.

scholarly journals Evaluation of Systemic Markers Related To Anemia of Chronic Disease in the Peripheral Blood of Smokers and Non-Smokers with Chronic Periodontitis

2008 ◽  
Vol 02 (02) ◽  
pp. 102-109 ◽  
Author(s):  
Ebru Olgun Erdemir ◽  
Rana Nalcaci ◽  
Osman Caglayan
Keyword(s):  
Chronic Disease ◽  
Cigarette Smoking ◽  
Chronic Periodontitis ◽  
Peripheral Blood ◽  
Clinical Parameters ◽  
Clinical Attachment Loss ◽  
Anemia Of Chronic Disease ◽  
Cell Parameters ◽  
Probing Depth ◽  
Age Range

ABSTRACTObjectives: The aim of this study was to investigate the effect of cigarette smoking on clinical parameters and signs anemia of chronic disease in chronic periodontitis patients.Methods: The study base consisted of 88 patients with chronic periodontitis including 45 volunteer current smokers with age range of 30-69 (45.5±8.5) and 43 volunteer non-smokers with age range of 32-61 years (45.8±7.9). The clinical parameters including plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL) were recorded and several red blood cell parameters were determined from peripheral blood samples.Results: In smokers, PI, PD and CAL were significantly higher than non-smokers (P<.05). The number of erythrocytes and the levels of hemoglobin, hematocrit and iron were lower in smokers compared to non-smokers (P<.05).Conclusions: In the present study, it is concluded that cigarette smoking may be effective on the signs of anemia of chronic disease in patients with chronic periodontitis. (Eur J Dent 2008;2:102-109)

scholarly journals Development and evaluation of a brief self-completed family history screening tool for common chronic disease prevention in primary care

2013 ◽  
Vol 63 (611) ◽  
pp. e393-e400 ◽  
Author(s):  
Fiona M Walter ◽  
A Toby Prevost ◽  
Linda Birt ◽  
Nicola Grehan ◽  
Kathy Restarick ◽  
...  
Keyword(s):  
Primary Care ◽  
Chronic Disease ◽  
Family History ◽  
Disease Prevention ◽  
Screening Tool ◽  
Chronic Disease Prevention ◽  
Common Chronic Disease

scholarly journals Genetic diversity and disease susceptibility

1997 ◽  
Vol 352 (1357) ◽  
pp. 1045-1050 ◽  
Author(s):  
Walter F. Bodmer
Keyword(s):  
Genetic Diversity ◽  
Chronic Disease ◽  
Disease Prevention ◽  
Life Insurance ◽  
Disease Susceptibility ◽  
Genomic Analysis ◽  
Human Populations ◽  
Common Chronic Disease ◽  
Clear Cut ◽  
Targeted Approach

The range of genetic diversity within human populations is enormous. Genetic susceptibility to common chronic disease is a significant part of this genetic diversity, which also includes a variety of rare, clear–cut, inherited diseases. Modern DNA–based genomic analysis can now routinely lead to the identification of genes involved in disease susceptibility, provides the basis for genetic counselling in affected families, and can be used more widely for a genetically targeted approach to disease prevention. This naturally raises problems concerning the use of information not just in an individulal's decisions, but also for employment, and health and life insurance.

scholarly journals Burning Mouth Syndrome: Case Reports

2020 ◽  
Vol 5 (4) ◽  
pp. 76-78
Author(s):  
Catarina da Costa Campos ◽  
Maria do Céu Ferreira ◽  
Joana Mesquita
Keyword(s):  
Psychological Factors ◽  
Case Reports ◽  
Burning Mouth Syndrome ◽  
Burning Sensation ◽  
Therapeutic Approaches ◽  
Physiological Factors ◽  
Common Chronic Disease ◽  
Clinically Normal ◽  
Nosological Entity ◽  
Burning Mouth

Burning mouth syndrome (BMS) is a relatively common chronic disease of unclear etiopathogenesis. It is defined as a distinctive nosological entity that includes all forms of burning sensation in the mouth, including stinging sensation or pain, in association with an oral mucosa that appears clinically normal, in the absence of local or systemic diseases. It was hypothesized that psychological factors could influence its appearance, but also physiological factors, with some authors suggesting a neuropathic etiology. Regarding the treatment of BMS, benefits were found in individual or group psychotherapy, as well as in psychopharmacological interventions, however its current therapeutic approach is not completely satisfactory. In this paper we describe two cases of BMS and discuss the possible etiopathogenesis and current therapeutic approaches.

scholarly journals The composition of microorganisms in the skin lesions focus in patients with seborrheic dermatitis

2019 ◽  
pp. 38-41
Author(s):  
Инна Одинцова ◽  
Анатолий Дюдюн
Keyword(s):  
Microscopic Examination ◽  
Blood Test ◽  
Inflammatory Process ◽  
Pathological Condition ◽  
Seborrheic Dermatitis ◽  
Skin Lesions ◽  
Pathogenic Microorganisms ◽  
Degree Of Contamination ◽  
Acinetobacter Spp ◽  
Malassezia Spp

The purpose of the work is monitoring the microbial landscape of the skin of patients with seborrheic dermatitis. Materials and research methods. We observed 67 patients with seborrheic dermatitis aged 18 to 57 years. The average age of the patients was 27.5 years. All patients with seborrheic dermatitis were examined using the following methods: skin examination; microscopic, bacteriological methods; a general and biochemical blood test; a general urinalysis; consideration of the patient's subjective sensations. Results and its discussion. Among patients with seborrheic dermatitis, fatty seborrhea was found in 39 (58 %), a mixed form of seborrheic dermatitis was found in 20 (30 %) patients. While bacteriological and microscopic examination of the sampling material from the affected areas of the skin of patients with seborrheic dermatitis is carried out, it is noteworthy to consider that in 59 (88.1%) patients Malassezia spp. is detected, which indicates a certain its value in the occurrence and course of the pathological condition. Among other microorganisms the examinations revealed: St. capitis - at 54 (80.1 %), St. epidermidis - at 36 (53.7 %), Micrococcus spp. - at 20 (29.9 %), Acinetobacter spp. - at 10 (14.9 %). With a lesser degree of contamination, St. aureus, St. capitis, St. hominis, St. cohnii, St. xylosus have been found. Conclusions. It is necessary to consider the presence of fungi Malassezia spp. in association with pathogenic and conditionally pathogenic microorganisms that support the inflammatory process and affect the development and course of the disease while planning the treatment of patients with seborrheic dermatitis.

scholarly journals Proposta de Protocolo para Redução dos Riscos e Otimização da Sensibilidade nos Exames de Imagem em Pessoas com Diabetes

2021 ◽  
Vol 34 (13) ◽  
Author(s):  
Sara Donato ◽  
Helder Simões ◽  
Paulo Donato
Keyword(s):  
Chronic Disease ◽  
Lactic Acidosis ◽  
Portuguese Population ◽  
Common Chronic Disease ◽  
Iodinated Contrast

Diabetes is a very common chronic disease in the Portuguese population, with an estimated prevalence of 13.6% in the adults. Doubts often arise regarding the best preparation and the risks associated with doing imaging tests in these patients. In this article we intend to review the main precautions in imaging tests in people with diabetes and to suggest a guideline to reduce the risks and optimize the sensitivity of these tests in this population. The main topics addressed in this article are the need to suspend metformin after the administration of endovascular iodinated contrast due to the risk of lactic acidosis, the precautions in insulin-treated patients or those taking medicines with a higher risk of hypoglycemia when performing imaging tests that require fasting, and the influence of hyperglycemia and of anti-diabetic therapy on the sensitivity of PET-FDG. With this review and the presentation of a guideline, we intend to demystify and simplify the management of individuals with diabetes who are undergoing imaging tests.

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