scholarly journals Risk Factors of First Febrile Seizures Admitted in a Tertiary Care Hospital

2018 ◽  
Vol 6 (1-2) ◽  
pp. 56-61
Author(s):  
Fauzia Nahid ◽  
Farhana Rahman ◽  
Md Mahbubul Hoque ◽  
Md Ruhul Amin ◽  
Tahmina Yasmin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Breast Feeding ◽  
Febrile Seizure ◽  
Perinatal Asphyxia ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Control Group ◽  
Care Hospital ◽  
History Of

Background & objective: Febrile seizure (FS) is the most common convulsive event in children. It is the most common type of seizure that every pediatrician has to deal with. However, the etiology of febrile seizure is still unclear. The present study was intended to identify the risk factors of first febrile convulsion among 6 months to 5 years old children. Materials & Methods: A case-control study was carried out on a total of 200 children-100 cases (children with febrile convulsion) & 100 controls (without febrile convulsion) selected from the In-patient Department of Dhaka Shishu Hospital over a period of six months between May 2012 to October 2012. Data were collected on variables of interest using a semi-structured research instrument. The Chi-square test and Odd Ratio were employed to compare the risk factors between case and control groups. Result: There was no association of febrile seizure with age of the children, but males were more often associated with FS than the females with risk of developing febrile seizures in boys was 3.5-fold (95% CI=1.8 -6.8) higher than that in girls (p<0.001). The risk of having FS in children with prematurity and caesarean delivery was 2.8 times (95% CI=1.5-5.0) and 2-times (95% CI=1.4-2.6) greater than those in children without having these conditions (p=0.001 and p<0.001 respectively). The children with family history of febrile seizure tends to be associated with first febrile seizures and the odds of having the condition is 36.4 (95% CI=15.4-85.7). There was no significant relationship between family history of epilepsy and first febrile seizure (p=0.061). The children with shorter duration of breast feeding (6-12 months) carry 2.9(95% CI=2.0-4.0) times higher risk of having first febrile seizure than those with longer duration of breast-feeding (p<0.001). Exclusively breast-fed children were less susceptible to develop febrile seizures (OR=0.149, 95% CI: 0.08-0.23). Twelve cases developed perinatal asphyxia as opposed to only 2 of the control group and the risk of having FS in children with perinatal asphyxia was 1.8(95% CI=1.4-2.3) times higher than those without having the history ofperinatal asphyxia (p<0.001). Three-quarters of the children presented with FS had viral fever whereas only 4% of the controls had viral fever indicating that viral fever triggers the development of FS much more frequently than any other childhood illness (p<0.001). Conclusion: The study concluded that male sex, preterm baby, positive family history of febrile seizures, less than 6 months of exclusive breast feeding, not continuing the breast-feeding beyond 12 months, perinatal asphyxia and viral infections are the predictors of first febrile seizure. Preventive measures in removing these risk factors can go a long way to a decrease the incidence of febrile seizures. Ibrahim Card Med J 2016; 6 (1&2): 56-61

scholarly journals A retrospective study of febrile seizures among children admitted in a tertiary care hospital

2020 ◽  
Vol 7 (11) ◽  
pp. 2112
Author(s):  
Maahir Mayan ◽  
Anitha S. Prabhu ◽  
Prakash Saldanha
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Febrile Seizure ◽  
Positive Family History ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Care Hospital

Background: Febrile convulsion is one of the commonest seizure disorders in children. Prevention of febrile convulsions is therefore desirable, and is of particular relevance in children with factors carrying a high risk of recurrence. Aim and objectives were to study the demographic profile and some risk factors of febrile seizures among children.Methods: Retrospective study was conducted at Pediatric department of Yenepoya Medical College, Mangalore. Considering inclusion & exclusion criteria all children in the 6 months to 5-year age who were diagnosed as having febrile convulsion admitted during January 2018 to October 2019 were included in the study.Results: Total out of the 96 children 53 (55.2%) were boys and 43 (44.7%) were girls. 61% children were in the 1-3-year age group. Mean age of occurrence was 2.2 years (±1.5 years). In this study, 81.25% (78) of the patients had simple and 18.75% (18) had the complex form of febrile seizure. In our study, 61.4% (59) of affected children had positive family history of febrile seizure. Acute gastroenteritis (AGE) (22.9%) followed by upper respiratory tract infection (URTI) and lower respiratory tract infection (LRTI) (20.8%) was the most common co-morbidity. 47.9% children were hospitalized for 1-3 days.Conclusions: Most of the children had a positive family history and the most common causative factor was Age, URTI, LRTI etc. are associated with febrile convulsion and these diseases can be managed effectively thereby reducing the occurrence of febrile convulsion.  

scholarly journals A retrospective study of febrile seizures among children admitted in a tertiary care hospital

2018 ◽  
Vol 5 (7) ◽  
pp. 3121
Author(s):  
Pralhad Sureshrao Potdar
Keyword(s):  
Family History ◽  
Febrile Seizure ◽  
Tertiary Care ◽  
Positive Family History ◽  
Complex Form ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Care Hospital ◽  
Cross Sectional ◽  
Co Morbidity

Background: Convulsion is the most common neurologic finding in children (10%). Prevention of febrile convulsions is therefore desirable, and is of particular relevance in children with factors carrying a high risk of recurrence. Aim and Objectives were to study the demographic profile and some risk factors of febrile seizures among children.Methods: A record based descriptive cross-sectional study was conducted at paediatric department of Dr. S.C.GMC, Nanded. Considering inclusion & exclusion criteria all children in the 6 month to 6 year age who were diagnosed as having febrile convulsion admitted during January to December 2015 were included in the study.Results: Of the 288 children 173 (60.1%) were boys and 115 (39.9%) were girls. 46.9% children were in the 1-3 year age group. Mean age of occurrence was 2.8 years (±1.5 years). In this study, 80.2% (231) of the patients had simple and 19.8% (57) had the complex form of febrile seizure. In our study, 51.73% (149) of affected children had positive family history of febrile seizure. URTI (9.7%) followed by AGE (7.3%) was the most common co-morbidity. 54.2% children were hospitalized for 1-3 days.Conclusions: Most of the children had a positive family history and the most common causative factor was URTI, LRTI, AGE etc. are associated with febrile convulsion and these diseases can be managed effectively thereby reducing the occurrence of febrile convulsion. 

scholarly journals Risk Factors of the First Febrile Seizures in Iranian Children

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Abolfazl Mahyar ◽  
Parviz Ayazi ◽  
Mazdak Fallahi ◽  
Amir Javadi
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Body Temperature ◽  
Breast Feeding ◽  
Febrile Seizures ◽  
The Body ◽  
Feeding Duration ◽  
Significant Difference ◽  
History Of ◽  
Iranian Children

Objective. Febrile seizures are the most common type of convulsion in children. The identification of influencing factors on incidence of the first febrile seizures is of prime priority. The aim of this study was to identify the risk factors of the first febrile seizures in Iranian children.Methods. In this case-control study 80 children aged 9 month to 5 years with their first febrile seizures were compared with 80 children with fever without seizure based on different risk factors in 2007.Results. There was significant difference between two groups regarding the gender, family history of febrile seizures, breast-feeding duration, and the body temperature (P<.05).Conclusion. Our study showed that factors including the gender, family history of febrile seizures, breast-feeding duration, and the body temperature are among the risk factors in occurrence of the first febrile seizure. Preventive measures to remove such risk factors could lead to lower the incidence of febrile seizures.

scholarly journals Risk factors for childhood obesity in a Greek paediatric population

2010 ◽  
Vol 13 (10) ◽  
pp. 1535-1539 ◽  
Author(s):  
Dimitrios Papandreou ◽  
Pavlos Malindretos ◽  
Israel Rousso
Keyword(s):  
Risk Factors ◽  
Childhood Obesity ◽  
Family History ◽  
Breast Feeding ◽  
Conditional Logistic Regression ◽  
Overweight And Obesity ◽  
Control Group ◽  
Paediatric Obesity ◽  
History Of ◽  
History Of Obesity

AbstractObjectiveObesity in children is a serious public health issue in Greece. The purpose of the current study was to identify risk factors such as birth weight, breast-feeding, dietary patterns, family history of obesity and sedentary behaviours that are possibly associated with paediatric obesity.DesignTwo hundred and five overweight and obese children (OW/OB; group 1) aged 7–15 years from eight primary and secondary schools and a control group (group 2) of normal-weight children were matched for age and sex. Overweight and obesity were calculated based on the International Obesity Taskforce criteria. Lifestyle parameters as well as anthropometric data were collected in all children. Conditional logistic regression analysis was used to identify risk factors for obesity.ResultsBreast-feeding (≥3 months) and leisure-time physical activity proved to be protector factors against obesity (OR = 0·21, 95 % CI 0·11, 0·79, P < 0·001 and OR = 0·87, 95 % CI 0·85, 0·89, P < 0·001 respectively). On the other hand, family history of obesity (OR = 3·79, 95 % CI 2·61, 4·18, P < 0·001), sugar-sweetened beverage consumption (OR = 1·77, 95 % CI 1·03, 2·76, P < 0·001) and watching television (OR = 1·99, 95 % CI 1·54, 2·76, P = 0·04) were found to be positively associated with a higher obesity risk.ConclusionsThe current findings support the literature according to which duration of breast-feeding (<3 months), a family history of obesity, watching television, sedentary lifestyle and consumption of sugar-sweetened beverages are important risk factors for childhood obesity. More studies are needed to elucidate the relationship of paediatric obesity and possible predictor factors in order to avoid health consequences in these children later on in life.

scholarly journals Study of risk factors and its correlation with constraint induced movement therapy for atherosclerosis in patients of coronary artery disease and their offspring

2020 ◽  
Vol 7 (3) ◽  
pp. 446
Author(s):  
Venugopal Margekar ◽  
Shweta Thakur ◽  
O. P. Jatav ◽  
Pankaj Yadav
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Positive Family History ◽  
Surrogate Marker ◽  
Control Group ◽  
Medical College ◽  
Constraint Induced Movement Therapy ◽  
Group Data ◽  
History Of ◽  
Artery Disease

Background: A significant percent of cardiovascular event occurs without well-known modifiable risk. A new tool for early identification for atherosclerosis is required for early intervention. Aims and objectives of the study was to study the risk factors for CAD and its correlation with CIMT.Methods: One hundred and forty subjects were studied for the risk factors of CAD in Department of Medicine of G.R. Medical College, Gwalior from 2012 to 2013. Out of 140 subjects, 100 were patients having CAD and 40 age matched subjects were included as control group. Data was also recorded from their offspring. High resolution B mode ultrasonography was performed to assess CIMT of carotid arteries. The maximum CIMT of any one side of carotid artery was taken for study.Results: CAD was more prevalent among males (78%). Majority of the offspring of cases had age between 28-42 years and majority were male (73%). Most common risk factors for CAD was dyslipidemia (48%), hypertension (24%), diabetes (12%) and smoking (21%), whereas in offspring’s of CAD patients, dyslipidemia was seen in 28%, hypertension in 3%, diabetes and tobacco smoking in 12% and 24% respectively. The CIMT of CAD patients was significantly increased with increasing the number of risk factors and the same pattern was also seen in controls.  The CIMT of asymptomatic offspring’s having positive family history was significantly more than the asymptomatic offspring without positive family history of CAD.Conclusions: CIMT measurements can be used as a surrogate marker of atherosclerosis as it has showed a direct link with number of risk factors of CAD. 

scholarly journals The Characteristics of Risk Factors in Chinese Young Women with Acute Coronary Syndrome

2020 ◽  
Author(s):  
Ruifang Liu ◽  
Fangxing Xu ◽  
Yujie Zhou ◽  
Tongku Liu
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Young Women ◽  
Early Onset ◽  
Young Female ◽  
Cardiac Insufficiency ◽  
Control Group ◽  
Significant Difference ◽  
Gynecological Diseases ◽  
History Of

Abstract Background In recent years, the prevalence rate of ACS in Chinese young women has been increasing significantly, becoming the main cause of death in young female. This study aimed to investigate the characteristics and difference of risk factors in Chinese young women with ACS and to provide references for ACS prevention and treatment. Methods A 1:1 case-control study was conducted to evaluate risk factors of 415 young female patients with ACS (ACS group) who underwent PCI treatment and 415 young female cases without ACS (control group) who were hospitalized and confirmed by coronary angiography to exclude coronary heart disease from January 2010 to August 2016. The average age of the cases in the two groups was respectively (40.77±4.02) years-old and (40.57±4.01) years-old (P> 0.05). Results The risk factors in ACS group were overweight (64.10%), hypertension (49.88%), hyperlipidemia (35.66%), diabetes (23.37%), depression or anxiety disorder (16.62%), gynecological diseases (16.39%), Hyperuricemia (15.18%), family history of early onset coronary heart disease (14.94%), hyperhomocysteinemia (11.33%), hypothyroidism(14.96%), hypercholesterolemia (8.43%) and high c-reactive protein (7.47%), and were statistically significant difference (P<0.01) compared with that of control group. The average number of risk factors per case in ACS group was significantly more than that of control groups (P<0.01). There was a statistically significant difference in the number of combined risk factors of the overweight cases compared between two groups (P<0.01). Regression analysis showed that hyperlipidemia, hyperhomocysteinemia, overweight（obesity）, high CRP, hypertension, hypothyroidism, gynecological diseases, depression or anxiety, cardiac insufficiency, hypercholesterolemia, diabetes, oral contraceptives, family history of early onset CHD, and autoimmune diseases were independent risk factors (P<0.01). The bivariate correlation analysis between CRP level and age was r= -0.158 (P<0.01). This result showed the younger ACS patient is the higher serum CRP. Conclusion The independent risk factors of ACS in young women are hyperlipidemia, hyperhomocysteinemia, overweight, high CRP, hypertension, hypothyroidism, gynecological diseases, depression or anxiety, cardiac insufficiency, hypercholesterolemia, diabetes, oral contraceptives, family history of early onset CHD, and autoimmune diseases. The co-existence of multiple risk factors is the main cause suffering from ACS in young women.

scholarly journals Major clinical risk factors for seizures in febrile children aged 6 to 60 months.

2020 ◽  
Vol 27 (05) ◽  
pp. 891-894
Author(s):  
Shahid Ishaq ◽  
Ejaz Mazari ◽  
Fazal ur Rehman
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Febrile Seizures ◽  
Study Groups ◽  
Clinical Risk Factors ◽  
P Value ◽  
Chi Square ◽  
Clinical Risk ◽  
Significant Difference ◽  
History Of

Objectives: Febrile seizures (FS) are the most common type of seizures and typically transpire in children with ages from 6 to 60 months. This study was planned to find out major clinical risk factors for seizures in febrile children who were aged 6 to 60 months. A total of 100 febrile children aged 6 to 60. Study Design: Analytical Study. Setting: Department of Neurology, Children’s Hospital and the Institute of Child Health, Multan. Period: From 1st April 2018 to 31st December 2018. Material & Methods: Group A had 40 children with febrile seizures while group B had 60 febrile children but without seizures. Demographic features along with family history of (H/O) epilepsy as well as family history of febrile seizure, types of seizure and infection diseases were noted and analyzed using SPSS version 20. Odds ratio was calculated for various risk factors. Chi square test was applied and P value < 0.05 was considered as significant. Results: Out of a total of 100 children, there were 54 (54.0%) male and 46 (46.0%) female. There was no statistical difference in terms of gender between the two groups (p value = 0.566). Overall, mean age of the children was 26.02 months with standard deviation of 13.4 months. There were 28 (70.0%) children who reported with simple seizures while complex seizures were found in 12 (30.0%) cases. Statistically significant difference (p value = 0.001) was seen in terms of types of infections between the two study groups. When risk of seizures for various risk factors was calculated, family H/O FS, family H/O epilepsy, and upper RTI were as 14, 7 and 3 times respectively and turned out to be the major risk factors for seizures in febrile children. Conclusions: Family H/O FS, family H/O epilepsy and upper RTIs are the major risk factors related with seizures in febrile children. Measures to prevent these risk factors can decrease the burden of FS in our population.

scholarly journals Study of correlation between breast feeding and wheezing in children

2018 ◽  
Vol 6 (1) ◽  
pp. 191
Author(s):  
Sagar Potharajula ◽  
Shreedhara Avabratha Kadke
Keyword(s):  
Family History ◽  
Breast Feeding ◽  
Cow’S Milk ◽  
Control Group ◽  
P Value ◽  
Chi Square ◽  
College Hospital ◽  
Cow's Milk ◽  
Breast Feed ◽  
History Of

Background: Wheezing is the most common chronic health problem in childhood. Many studies have found protective effect of breastfeeding on wheezing, while few others have not. Hence this study was taken up to find out the correlation between breastfeeding and wheezing in children.Methods: Case control study done in a Medical College Hospital. Cases were children of 2-5yrs age with history of wheezing or who had received nebulisation. Controls were children without history of wheezing or nebulisation. Mothers were interviewed with a predesigned proforma. Results were analysed by Chi square test and Odd’s ratio and p value <0.05 was considered significant.Results: There were 92 cases and 184 controls. Sixteen (53.4%), 48 and 27 cases were breastfed less than 1year, till 2yrs and beyond 2yrs respectively. 14 (46.6%), 128, and 40 were the numbers in control group. Breast feeding duration till 1 year of age is statistically correlated with wheezing with p value of 0.02, higher proportion of children who were breastfed for less than 1 year had wheezing when compared to controls. 26 cases out of 69 were not exclusively breast fed till 6 months and 66 cases out of 207 were exclusively breastfed. Higher proportion of cases who were not exclusively breastfed had developed wheeze although it was not significant statistically. 45 cases (36.8%) were initiated on cow’s milk before 1yr of age, 47 cases (30.5%) were initiated after 1year. Higher proportion of children who were initiated on cow’s milk early had developed wheeze but was not significant statistically. 34 cases and 24 controls had family history of asthma. With family history wheezing episodes were 3.72 times more likely irrespective of breast-feeding duration.Conclusions: Breast feeding gives protection against wheezing in children. Mothers should be encouraged to breast feed their children.

scholarly journals Risk Factors for Gall Stone Diseases in Patients Presenting to General Practice Out Patient Department in a Tertiary Care Center in Nepal

2019 ◽  
Vol 41 (2) ◽  
pp. 26-29
Author(s):  
Ram P. Neupane ◽  
Tirtha M Shrestha ◽  
Shankar Raut ◽  
Ramesh P Aacharya
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
General Practice ◽  
Family History ◽  
Gall Stone ◽  
Vegetarian Diet ◽  
Stone Disease ◽  
Control Group ◽  
Gall Stone Disease ◽  
History Of

Introduction: Gallstone disease (GSD) is a major public health problem that is associated with a number of risk factors. This study aims to analyze the risk factors of GSD in patients visiting General Practice Outpatient Department of Tribhuvan Universtiy Teaching Hospital. Methods: A case-control study of 174 participants comprising 85 cases with GSD and 89 controls without GSD, as confirmed by ultrasonography of abdomen was conducted as hospital based in outpatient department of General practice, Tribhuvan University Teaching Hospital, Kathmandu from 1st February 2018 to 31st January, 2019. The participants were asked questions regarding putative risk factors for development of GSD and underwent physical and ultra sonographic examination. Risk factors included were age, sex, BMI, occupation, co-morbidities e.g. diabetes mellitus, hemolytic diseases, family history of GSD, smoking status, alcohol consumption, parity if applicable and dietary history. Data analysis was done by univariate method. Results: The mean age of the case group was 47.82 years whereas mean age for the control was 46.51 years (p=0.355). 22% of cases were male and 78% were female where as in control group 29% were male (p=0.3030). Majority of the participants in both group were housewife by occupation and Hindu by religion. Mean BMI of the cases and control were 24.05 kg/m2 and 21.13kg/m2 respectively. BMI was found significant for the gall stone diseases (p=<0.001). Similarly, Diabetes mellitus was found significant for GSD (p=0.001). 98% cases and 61% in control group were Non-vegetarians with significant p value of 0.021. Smoking (p=0.005), Non-vegetarian diet (p=0.021), family history of gall stone disease (p<0.001) and parity (p<0.001) were also found significant for the gall stone disease. Conclusion: High BMI, non-vegetarian diet, family history of gall stone disease, diabetes mellitus, smoking and increased parity were associated with gall stone diseases.

Retrospective Study of Febrile Seizures: Subsequent Electroencephalogram Findings, Unprovoked Seizures and Epilepsy in Adolescents

2002 ◽  
Vol 30 (6) ◽  
pp. 560-565 ◽  
Author(s):  
HN Piperidou ◽  
IN Heliopoulos ◽  
ES Maltezos ◽  
GA Stathopoulos ◽  
IA Milonas
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Secondary School ◽  
Febrile Seizure ◽  
Age At Onset ◽  
Febrile Seizures ◽  
Unprovoked Seizure ◽  
History Of ◽  
The Mean ◽  
Retrospective Questionnaire

A retrospective questionnaire to determine the prevalence of febrile seizures was given to adolescents (16- and 17-year-olds) in the final 2 years of secondary school at the five schools in Alexandroupolis, Greece. Parents were interviewed, and clinical and electroencephalographic examinations were performed in all adolescents with a history of febrile seizures. Of 1708 adolescents, 56 (3.3%) had experienced at least one febrile seizure. Of these, 44 (78.6%) were simple and 12 (21.4%) were complex febrile seizures. Recurrent seizures occurred in 22 cases (39.3%), and the mean age at onset was 25.1 months. There was a positive first-degree family history in eight cases (14.3%) and this increased to 27.3% in cases with recurrent seizures. Two of the adolescents (3.6%) had had one unprovoked seizure before the age of 3 years, and another two children developed epilepsy. Epileptiform electroencephalogram discharges were observed in only one case (1.8%) with generalized tonic-clonic epilepsy.

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