scholarly journals A retrospective study of febrile seizures among children admitted in a tertiary care hospital

2020 ◽  
Vol 7 (11) ◽  
pp. 2112
Author(s):  
Maahir Mayan ◽  
Anitha S. Prabhu ◽  
Prakash Saldanha

Background: Febrile convulsion is one of the commonest seizure disorders in children. Prevention of febrile convulsions is therefore desirable, and is of particular relevance in children with factors carrying a high risk of recurrence. Aim and objectives were to study the demographic profile and some risk factors of febrile seizures among children.Methods: Retrospective study was conducted at Pediatric department of Yenepoya Medical College, Mangalore. Considering inclusion & exclusion criteria all children in the 6 months to 5-year age who were diagnosed as having febrile convulsion admitted during January 2018 to October 2019 were included in the study.Results: Total out of the 96 children 53 (55.2%) were boys and 43 (44.7%) were girls. 61% children were in the 1-3-year age group. Mean age of occurrence was 2.2 years (±1.5 years). In this study, 81.25% (78) of the patients had simple and 18.75% (18) had the complex form of febrile seizure. In our study, 61.4% (59) of affected children had positive family history of febrile seizure. Acute gastroenteritis (AGE) (22.9%) followed by upper respiratory tract infection (URTI) and lower respiratory tract infection (LRTI) (20.8%) was the most common co-morbidity. 47.9% children were hospitalized for 1-3 days.Conclusions: Most of the children had a positive family history and the most common causative factor was Age, URTI, LRTI etc. are associated with febrile convulsion and these diseases can be managed effectively thereby reducing the occurrence of febrile convulsion.  

Author(s):  
Pralhad Sureshrao Potdar

Background: Convulsion is the most common neurologic finding in children (10%). Prevention of febrile convulsions is therefore desirable, and is of particular relevance in children with factors carrying a high risk of recurrence. Aim and Objectives were to study the demographic profile and some risk factors of febrile seizures among children.Methods: A record based descriptive cross-sectional study was conducted at paediatric department of Dr. S.C.GMC, Nanded. Considering inclusion & exclusion criteria all children in the 6 month to 6 year age who were diagnosed as having febrile convulsion admitted during January to December 2015 were included in the study.Results: Of the 288 children 173 (60.1%) were boys and 115 (39.9%) were girls. 46.9% children were in the 1-3 year age group. Mean age of occurrence was 2.8 years (±1.5 years). In this study, 80.2% (231) of the patients had simple and 19.8% (57) had the complex form of febrile seizure. In our study, 51.73% (149) of affected children had positive family history of febrile seizure. URTI (9.7%) followed by AGE (7.3%) was the most common co-morbidity. 54.2% children were hospitalized for 1-3 days.Conclusions: Most of the children had a positive family history and the most common causative factor was URTI, LRTI, AGE etc. are associated with febrile convulsion and these diseases can be managed effectively thereby reducing the occurrence of febrile convulsion. 


2021 ◽  
Vol 8 (10) ◽  
pp. 1700
Author(s):  
Shrikant Joshi ◽  
Kamil Shaikh ◽  
Vrushali V. Kulkarni

Background: World health organization (WHO) predicted lower respiratory tract infections (LRTI) as primary cause of mortality world-wide. The present study was undertaken to know the various types of LRTI in children <5 years of age and analyze factors influencing the morbidity and mortality of those cases.Methods: Prospective cross-sectional study for 100 infected children with LRTI was conducted in a tertiary care hospital of metropolitan city. Demographic, clinical history and examination, necessary investigations were performed and followed regularly for desired outcome.Results: 51% children were in the age-group of 1 to 5 years who reported acute lower respiratory tract infection (ALRTI) and 49% were below 1 year age. The study reported LTRI incidence in 63% male and 37% female children whereas the family history of incidence of LRTI was present in 18% cases. Fever, cough and retraction complaints were the prominent symptoms. Hyperinflation was the major finding in chest X-ray. Streptococcus pneumoniae was the common bacterial pathogens isolated. Bronchiolitis was the commonest cause (39%) followed by lobar pneumonia (37%).Conclusions: Various types of clinical presentations, risk factors and types of LRTI in children less than 5 years of age were studied. A result of this study will be useful to understand the etiology and bacterial pathogens in management of clinical outcome. Modifiable risk factors for LRTI like family history, past history, immunization status, and malnutrition can be tackled through effective health education of the community, leading to a healthy society.


2018 ◽  
Vol 6 (1-2) ◽  
pp. 56-61
Author(s):  
Fauzia Nahid ◽  
Farhana Rahman ◽  
Md Mahbubul Hoque ◽  
Md Ruhul Amin ◽  
Tahmina Yasmin ◽  
...  

Background & objective: Febrile seizure (FS) is the most common convulsive event in children. It is the most common type of seizure that every pediatrician has to deal with. However, the etiology of febrile seizure is still unclear. The present study was intended to identify the risk factors of first febrile convulsion among 6 months to 5 years old children. Materials & Methods: A case-control study was carried out on a total of 200 children-100 cases (children with febrile convulsion) & 100 controls (without febrile convulsion) selected from the In-patient Department of Dhaka Shishu Hospital over a period of six months between May 2012 to October 2012. Data were collected on variables of interest using a semi-structured research instrument. The Chi-square test and Odd Ratio were employed to compare the risk factors between case and control groups. Result: There was no association of febrile seizure with age of the children, but males were more often associated with FS than the females with risk of developing febrile seizures in boys was 3.5-fold (95% CI=1.8 -6.8) higher than that in girls (p<0.001). The risk of having FS in children with prematurity and caesarean delivery was 2.8 times (95% CI=1.5-5.0) and 2-times (95% CI=1.4-2.6) greater than those in children without having these conditions (p=0.001 and p<0.001 respectively). The children with family history of febrile seizure tends to be associated with first febrile seizures and the odds of having the condition is 36.4 (95% CI=15.4-85.7). There was no significant relationship between family history of epilepsy and first febrile seizure (p=0.061). The children with shorter duration of breast feeding (6-12 months) carry 2.9(95% CI=2.0-4.0) times higher risk of having first febrile seizure than those with longer duration of breast-feeding (p<0.001). Exclusively breast-fed children were less susceptible to develop febrile seizures (OR=0.149, 95% CI: 0.08-0.23). Twelve cases developed perinatal asphyxia as opposed to only 2 of the control group and the risk of having FS in children with perinatal asphyxia was 1.8(95% CI=1.4-2.3) times higher than those without having the history ofperinatal asphyxia (p<0.001). Three-quarters of the children presented with FS had viral fever whereas only 4% of the controls had viral fever indicating that viral fever triggers the development of FS much more frequently than any other childhood illness (p<0.001). Conclusion: The study concluded that male sex, preterm baby, positive family history of febrile seizures, less than 6 months of exclusive breast feeding, not continuing the breast-feeding beyond 12 months, perinatal asphyxia and viral infections are the predictors of first febrile seizure. Preventive measures in removing these risk factors can go a long way to a decrease the incidence of febrile seizures. Ibrahim Card Med J 2016; 6 (1&2): 56-61


2021 ◽  
Vol 8 (10) ◽  
pp. 1658
Author(s):  
Chandrakala P. ◽  
Vinutha Patil ◽  
Kavya V. N. ◽  
Sushmitha .

Background: Community acquired pneumonia remains a significant cause of morbidity and mortality due to infection all over the world. Thrombocytes are known to be an essential part of immune response to various infectious agents. Platelet count elevated more than normal is often sign of severe pneumonia according to various studies.Methods: This is a retrospective study conducted in Kempegowda Institute of Medical Science, a tertiary care hospital in Bangalore with a study duration of 1 year. All children were classified into two groups based on platelet count that is with thrombocytosis and without thrombocytosis. Respiratory distress was defined as presence of tachypnoea, chest retractions, oxygen saturation <94% in room air. Children with respiratory distress were classified as severe pneumonia and those with no respiratory distress as non-severe pneumonia.Results: A total of 213 children were admitted with lower respiratory tract infection of which 35 children were excluded based on exclusion criteria. Of these 178 children 142 (80%) belonged to non-severe pneumonia group and 36 (20%) belonged to severe pneumonia group. Thrombocytosis is found in 31 (17%) children, 147 (82%) children had platelet count less than 4.5 lakhs/cu mm. Of these children with thrombocytosis 13 (42%) had non severe pneumonia and 18 (58%) had severe pneumonia. The p<0.0000001 which showed statistical significance, that is thrombocytosis was significantly associated with severity of pneumonia.Conclusions: Thrombocytosis can be considered as a marker of severity of pneumonia in day-to-day practice.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yuanyuan Qi ◽  
Peng Shi ◽  
Renjie Chen ◽  
Yufeng Zhou ◽  
Lijuan Liu ◽  
...  

Abstract Background The prevalence of allergic diseases (ADs), such as asthma and allergic rhinitis (AR), is increasing worldwide in both adults and children. Although ADs are common and frequently coexist in outpatient care, city-level data regarding the characteristics of childhood AD remain limited in China. This study aimed to assess the profile and characteristics of ADs in the city of Shanghai. Methods A multicenter retrospective study was designed to collect routine administrative data from outpatient and emergency departments from 66 hospitals in Shanghai, China, from 2016 to 2018. Children with asthma, AR, allergic conjunctivitis (AC), and allergic skin diseases were investigated. Demographic characteristics, patients visit pattern, spectrum of diagnosis, and comorbidities were analyzed. Results A total of 2,376,150 outpatient and emergency visits for ADs were included in the period from 2016 to 2018. Allergic skin diseases accounted for 38.9%, followed by asthma (34.8%), AR (22.9%), and AC (3.3%), with a male predominance in all four diseases. Asthma and allergic skin diseases were most frequent in the 1 to < 4 years of age group, while AR and AC were more common in the 4 to < 7 years of age group. Asthma accounted for the greatest number of annual and emergency visits. The most frequent comorbidity of asthma was lower respiratory tract infection (LRTI) (49.3%), followed by AR (20.5%) and upper respiratory tract infection (14.1%). The most common comorbidities of AR were otitis media (23.4%), adenoid hypertrophy/obstructive sleep apnea (22.1%), followed by LRTI (12.1%), asthma (9.4%) and chronic pharyngitis (8.9%). Conclusions Asthma and allergic skin diseases were the most common ADs in outpatient and emergency departments in the study period. Respiratory tract infection was the most common comorbidity of asthma in children. More attention should be devoted to the treatment of comorbidities to improve childhood AD outcomes with a better understanding of the characteristics of ADs in outpatient care.


2020 ◽  
Vol 7 (7) ◽  
pp. 1589
Author(s):  
Kumari Pratima ◽  
Shivlok Narayan Ambedkar ◽  
Jagannath Mohapatra

Background: Vitamin D plays important role in immunity and its deficiency might be associated with increased risk of lower respiratory tract infection. This study aimed to determine whether vitamin D deficiency is commoner in infants with acute lower respiratory tract infection as compared to normal infants and to correlate the severity of vitamin D deficiency with severity of ALRTI.Methods: A hospital based prospective case-control study was conducted in a tertiary care hospital. A total of 208 infants (109 cases and 99 controls) older than 7 days to 12 months of age, were enrolled. Cases were selected according to the definition of ALRTI given by WHO (2). Controls were chosen from children attending paediatric outpatients department for immunization or minor short duration aliments. Primary outcome measured as serum 25-hydroxy vitamin D3 (25OHD3) levels and severity of ALRTI was independent variable.Results: Among 109 cases suffering from ALRTI, vitamin D deficiency was present in 65.11%, 92.3%, 88.9% children of ‘pneumonia, severe pneumonia and very severe pneumonia group respectively. It was found that vitamin D deficiency was commoner in cases as compared to controls (80.70 % vs 25.50% ) with OR of 12.40 (95 % CI was 6.13 - 25.38). There was inverse relationship between the severity of ALRTI and Vitamin D levels (p value <0.001 and Pearson correlation coefficient -0.32).Conclusions: Vitamin D levels were significantly lower in ALRI cases as compared to controls and had negative correlation between vitamin D levels and severity of pneumonia.


2017 ◽  
Vol 4 (2) ◽  
pp. 442
Author(s):  
Alex Aiswariya ◽  
Kundoly Velayudhan Suseela ◽  
Das Subi

Background: Moraxella catarrhalis is a Gram-negative diplococcus, commonly found as a normal flora in the human upper respiratory tract. Recently, M. catarrhalis has emerged as an important and common human respiratory tract pathogen. This study was aimed to determine the rate of isolation of M. Catarrhalis in patients attending a tertiary care hospital with lower respiratory tract infection (LRTI), antibiotic susceptibility pattern and predisposing factors responsible for their infection.Methods: A prospective study was carried out in 1001 lower respiratory specimens from patients (above 20 years’ age) with suspected LRTI.  The study investigated by microscopic examination, culture and antibiotic sensitivity test according to the standard guidelines. Assessment of clinical significance of M. Catarrhalis was ascertained on the basis of preformed criteria.Results: A total of 60 clinically significant M. Catarrhalis were isolated from the 930 culture positive samples. The isolates showed maximum sensitivity to second and third generation cephalosporins (95%), azithromycin (90%) followed by amoxicillin clavulanic acid (85%). Rate of isolation was more in males (70%) and elderly people above 60 years (63.33%) were found to be more affected. Patients (58.33%) with Chronic Obstructive Pulmonary Diseases (COPD) were found to be more prone to get infection by M. Catarrhalis.Conclusions: Moraxella catarrhalis should be considered as significant lower respiratory tract pathogen especially in elderly patients with underlying risk factors like COPD.


Author(s):  
Hubballi Ravi Kishore ◽  
Reshma P. R.

<p><strong>Background:</strong> Chronic otitis media equates with the term chronic suppurative otitis media that is no longer advocated as it is not necessarily a result of the gathering of pus. Incidence of this disease is higher in developing countries especially among lower socioeconomic society because of malnutrition, overcrowding, poor hygiene, inadequate health care facility and recurrent upper respiratory tract infection.</p><p><strong>Methods: </strong>Eighty patients with chronic otitis media were included. After obtaining written and informed consent, they were subjected to detailed history taking and examination. Various risk factors of chronic otitis media and the morbidity caused by the disease were studied. Data was analyzed using IBM SPSS version 22.<strong></strong></p><p><strong>Results: </strong>The most common age group was 21-30 years with male predominance. Central perforation was the most common type of perforation. Various factors like low socioeconomic status, rural setup, overcrowding, malnutrition, indoor cooking, recurrent acute otitis media, recurrent upper respiratory tract infection, naso-respiratory allergies, habit of swimming, taking bath in pond, ear probing were found to cause the onset of the disease and worsen of the disease process.<strong></strong></p><p><strong>Conclusions: </strong>Chronic otitis media results in various morbidity including increased financial burden, restricts daily activities, hence affects the psychological mindset and lowers the confidence of the patient giving them a feeling of social outcast. A proper awareness must be spread regarding these factors, maintaining personal hygiene, improving nutrition and immunity. An immediate consultation with the otorhinolaryngologist will reduce the disease progression and hence the complications. <strong></strong></p>


2002 ◽  
Vol 30 (6) ◽  
pp. 560-565 ◽  
Author(s):  
HN Piperidou ◽  
IN Heliopoulos ◽  
ES Maltezos ◽  
GA Stathopoulos ◽  
IA Milonas

A retrospective questionnaire to determine the prevalence of febrile seizures was given to adolescents (16- and 17-year-olds) in the final 2 years of secondary school at the five schools in Alexandroupolis, Greece. Parents were interviewed, and clinical and electroencephalographic examinations were performed in all adolescents with a history of febrile seizures. Of 1708 adolescents, 56 (3.3%) had experienced at least one febrile seizure. Of these, 44 (78.6%) were simple and 12 (21.4%) were complex febrile seizures. Recurrent seizures occurred in 22 cases (39.3%), and the mean age at onset was 25.1 months. There was a positive first-degree family history in eight cases (14.3%) and this increased to 27.3% in cases with recurrent seizures. Two of the adolescents (3.6%) had had one unprovoked seizure before the age of 3 years, and another two children developed epilepsy. Epileptiform electroencephalogram discharges were observed in only one case (1.8%) with generalized tonic-clonic epilepsy.


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