Thyroid Status of Infertile Women Attending at Infertility Outdoor in BSMMU

2015 ◽  
Vol 32 (4) ◽  
pp. 206-210
Author(s):  
Farzana Deeba ◽  
Parveen Sultana ◽  
Shiuly Chowdhury ◽  
Parveen Fatima ◽  
Jesmin Banu ◽  
...  

Aim: To evaluate the thyroid status in infertile women.Materials and methods: A cross sectional study was conducted in the department of Infertility of Bangabandhu Shaekh Mujib Medical University from January 2012 to December 2012. A total 400 patients of infertility were studied. The thyroid function status of the subjects were assessed and analyzed.Results: Of the 400 women enrolled for the study, 221(55%) patients with primary infertility and 179 (45%) patients were with secondary subfertility. The mean age of the responders were 22.3±4.6 years, the mean duration of marriage were 4.5±1.2 years and mean BMI were 23.2±3.1 kg/m2.Among the 400 patients 70.50% that is 293 patients were euthyroid, TSH level was increased in 23% or in 92 subjects. Depending upon the TSH levels, hypothyroid infertile women were further subdivided into subclinical hypothyroidism where TSH 4–6 mIU/L with normal FT4 (9-24 pmol/L) and clinical hypothyroidism where TSH > 6 mIU/L with raised FT4 level. It was found that 66 (71.74%) of hypothyroid infertile women were with subclinical and remaining 26 (28.26%) were with clinical hypothyroidism.Hyperthyroidism that is low TSH level (<.5 mIU/L) found in 15(3.75%) subjects and visible goiter was present in only 2 patients. In 96 hypothyroid infertile females, the mean TSH levels were 7.34 ± 2.13 mIU/L, and mean FT4 level was 17.34±3.23pmol/L. The mean PRL levels were 52.46 ±11.17 ng/ml.Conclusion: Thyroid dysfunction is an important factors for infertility. Early diagnosis and timely intervention can reduce the burden of infertility due to thyroid dysfunction.J Bangladesh Coll Phys Surg 2014; 32: 206-210

KnE Medicine ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 202
Author(s):  
Muhammad D. Priangga ◽  
Gita Pratama ◽  
Mila Maidarti ◽  
Achmad K. Harzif ◽  
Budi Wiweko

<p><strong>Introduction</strong></p><p>Infertility in Indonesia has an estimated prevalence as high as 22.3%, with the nature of the problem and its treatment could be devastating, it could affect quality of life and vice versa influence successful of the treatment. The Fertility Quality of Life (FertiQol) Questionnaire was specifically designed for infertility couples and has been demonstrated to have good properties. Studies in several countries has showed consistency in validity and reliability of the questionnaire. Precedently there has been no published study about Fertiqol in Indonesia, this preliminary study is to measure validity and reliability of FertiQol questionnaire among Indonesian infertility women.</p><p><br /> <strong>Material &amp; Methods</strong></p><p>This is a cross-sectional study, a written Fertiqol Questionnaire Indonesian version (www.Fertiqol.org) were distribute to Infertility clinic in Cipto Mangunkusumo General Hospital, total of 129 women completed the questionnaire. Statistical analysis used SPSS version 23.0. The questionnaire were tested for validity with Pearson’s correlation with two tailed and Cronbach α coefficient for reliability.<br /> <strong></strong></p><p><strong>Results</strong></p><p>FertiQol were completed by 129 women with infertility problem. The mean of total FertiQol score was 70.49±11.44, score for emotional, mind/body, relational, environment and tolerability was respectively 63.79±18.86; 66.05±18.22; 75.19.±15.11; 68.99±18.63; 75.64±16.55; 66.23±19.17. Reliability of Fertiqol was high (Cronbach a &gt; 0.70) with every item of questionnaires was valid ( r&gt; 0.1729).<br /> <strong></strong></p><p><strong>Conclusion</strong></p><p>This study showed that FertiQol Indonesian version are valid and reliable in measured quality of life among infertility women in Indonesia.</p>


Author(s):  
Naivah Harharah

Objective: To compare serum Anti Müllerian Hormone (AMH) levels in infertile women with and without endometriosis, and to determine the mean levels of serum AMH in every stage of endometriosis. Method: We performed a cross-sectional study. Sixty-eight subjects who have undergone laparoscopy and fulfilled both inclusion and exclusion criteria are recruited consecutively. They are divided into two groups, namely group with endometriosis and without endometriosis. Blood samples are taken from each subject before laparoscopy, where serum AMH levels are then measured. The difference in mean levels of each group are tested with Mann-Whitney test. Result: The mean levels of serum AMH were significantly lower in the endometriosis group than those in the group without endometriosis (2.30 1.8 ng/ml vs 3.75 2.13 ng/ml; p=0.005). Using Kruskal-Wallis test, it was found that there was a statistically significant difference among endometriosis groups based on the severity of endometriosis. There was no significant difference in the mean serum AMH levels between the minimal-mild endometriosis group and without endometriosis group (p=0.34), but the mean levels of serum AMH were significantly lower in the moderate-severe endometriosis compare to the group without endometriosis (p


2016 ◽  
Vol 7 (3) ◽  
pp. 82-88
Author(s):  
Ruaa E Alabd ◽  
Kefah H Abdulmajeed ◽  
Hayder G Oufi

ABSTRACT Aims This work was designed to assess the role of diet and dietary habits on women fertility. Materials and methods This study was carried out in seven different centers and hospitals in Baghdad in the period between January and September 2014. Participants were 400 adult women selected conveniently; their age ranged from 17 to 47 years and they were divided into two groups. Group I included 300 fertile women and group II included 100 infertile women. A specific questionnaire had been designed and used for data collection Results It was found that there was a significant difference in weight and body mass index (BMI) between the infertile group and control group. The mean of weights was 73.07 vs 69.06 kg for infertile and the control group respectively, while the mean BMI was 28.83 vs 26.70 for the infertile group and the control group respectively. Moreover, the infertile women consumed more of carbonated beverages, tea, chicken, and fish than the control group, while they consumed less milk and red meat than the control group. Also, the infertile group consumed less corn oil and olive oil than the control group (5 and 0% vs 21 and 2%) respectively, while they used to consume more solid fat and combined fat than the control group (2 and 6% vs 0 and 2.7%) respectively. Conclusion Although treatment options for infertility are available, their high cost and frequency of adverse events have motivated the identification of dietary factors related to infertility. The current study identified diet as one of the modifiable risk factors that potentially impacts fertility in the selected groups; hence, it is important to focus more on the role of diet in women fertility and increase the awareness of women to it, along with suggesting more educational programs at the primary health care level. How to cite this article Alabd RE, Abdulmajeed KH, Oufi HG. Diet and Women Fertility: A Descriptive Cross-sectional Study. Int J Infertil Fetal Med 2016;7(3):82-88.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Farnaz Sohbati ◽  
Seyedeh Batool Hasanpoor-Azghady ◽  
Mina Jafarabadi ◽  
Leila Amiri-Farahani ◽  
Marzieh Mohebbi

Abstract Background Infertility leads to a wide range of psychological injuries that may reduce psychological well-being. This study aimed to determine the psychological well-being of infertile women and its relation with demographic factors and fertility history. Methods This cross-sectional study was conducted on 300 infertile women referred to three infertility centres, Tehran, Iran. The sampling was continuous. We collected data from a self-generated demographic and fertility questionnaire and Ryff's Psychological Well-being Scale (PWB). Data analysis was done by independent t-test, one way ANOVA. The significance level was set at P < 0.05. Results The results showed that there was no significant relationship between demographic variables including age, occupation of each couple, spousal’s education, economic status and place of residence with PWB, but the mean score of PWB was significantly different in women's educational levels (P = 0.03). There was also a significant difference between the mean score of PWB among different groups in the duration of marriage (P = 0.01). Fertility characteristics variables include the duration of infertility, duration of treatment of infertility, and current treatment were not the relation with PWB. However, the mean score of PWB in the number of IVF (P = 0.003) and the failed IVF pregnancies (P = 0.01) had a significant statistical difference. Conclusion The results showed that PWB related to several variables. Paying attention to these variables can help in the preparation and development of counseling or educational programs.


2020 ◽  
Author(s):  
Mohammad Naeem Lakanwall ◽  
Sibtain Ahmed Ahmed ◽  
Shabnam Azizi ◽  
Jamshid Jalal ◽  
Ahmed Maseh Haidary ◽  
...  

Abstract Objective: Endocrinopathies are a commonly occurring entity, particularly those of the thyroid gland, however there is death of scientific literature from Afghanistan, a country with very limited health care facilities and resources. This is the first study aimed to describe the frequency of occurrence and factor associated with thyroid dysfunction in Afghan population. The aim of this study is to estimate the frequency and to identify factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan.Methods: A cross-sectional study was conducted from July to Sep 2018 at the Department of Clinical Pathology, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan. Blood samples were obtained, serum TSH levels were analyzed, and the patients were divided into three diagnostic categories according to their serum TSH concentrations: 1) Hypothyroidism 2) Hyperthyroidism 3) normal.Results: A total of 127 individuals were included in the final analysis. Majority study participants (77%) were females. A large number of the participants (92%) did not have family history of thyroid dysfunction. (74%) participants in the study had normal TSH levels classified as normal thyroid function, (14%) had lower TSH levels and (12%) higher TSH levels (Table 1) classified as hyper and hypothyroid respectively.Conclusion: The findings of the current study showed a high frequency of thyroid dysfunctions from a single center. Further large scale studies are needed to find out the prevalence and document this entity for better health outcomes in the country.


Author(s):  
Elahe Dehghan ◽  
Nasim Namiranian ◽  
Akram Ghadiri-Anari ◽  
Seid Kazem Razavi Ratki ◽  
Reyhaneh Azizi

Background: Hyperprolactinemia is one of the most common causes of infertility in women. The prevalence of pituitary tumors is 25-30% among infertile participants with hyperprolactinemia. Objective: The aim of this study was to describe the causes of hyperprolactinemia in infertile women referred to Yazd Infertility Center. Materials and Methods: This cross-sectional study was conducted with 182 infertile women with hyperprolactinemia who were referred to Yazd Infertility Center from February 2018 to October 2019. Serum prolactin was assessed by the human prolactin ELISA kit according to the Padtan Gostar Isar protocol. The age, duration of infertility, causes of hyperprolactinemia, and type of infertility treatment were noted. The MRI findings were added. Results: The mean age of participants was 28.9 ± 0.36 yr and the prolactin level was 76 ± 8.97 ng/ml. The etiology of hyperprolactinemia among the study participants was 35 participants (19.2%) with pituitary adenoma, 47 participants (25.8%) with polycystic ovary syndrome, 14 participants (7.7%) with pituitary adenoma and polycystic ovary syndrome, and 86 participants (47.3%) with idiopathic hyperprolactinemia. The results of this study showed that there was no statistically significant difference between the mean prolactin levels in participants with different causes of hyperprolactinemia (p = 0.31). Conclusion: Idiopathic hyperprolactinemia and polycystic ovary syndrome are the most common reasons for hyperprolactinemia. Key words: Hyperprolactinemia, Infertility, PCOS.


Author(s):  
Sedigheh Amooee ◽  
Mojgan Akbarzadeh-Jahromi ◽  
Maedeh Motavas ◽  
Fatemeh Zarei

Background: Infertility is a critical condition in women with polycystic ovary syndrome (PCOS), caused not only by anovulation but also by endometrial abnormality. Objective: This study aimed to evaluate and compare the hysteroscopic and histological findings of endometrial biopsies in infertile women with PCOS and normal endometrial thickness and women with unexplained infertility (UI). Materials and Methods: This cross-sectional study compared the initial hysteroscopy and endometrial histological findings of 70 infertile women with PCOS and normal endometrial thickness with those of 35 women with UI. The relationship between endometrial histology and clinical parameters such as including luteinizing hormone, follicle-stimulating hormone, thyroid-stimulating hormone, testosterone, prolactin, fasting blood sugar, body mass index (BMI), and infertility duration was analyzed. Results: The mean age of women with PCOS was significantly lower than that of women with UI (27.5 ± 4.1 vs. 30 ± 4.5 years, respectively) (p < 0.001). The mean BMI was higher in women with PCOS than in women with UI (28.7 ± 4.4 vs. 25.1 ± 3 kg/m2) (p < 0.001). The hysteroscopic findings of all women with PCOS were normal, whereas 91.4% of women with UI had normal hysteroscopic findings, 2.9% had a polyp, and 5.7% had endometrial thickening. The histological findings of women with PCOS revealed proliferative endometrium in 54.3%, disordered proliferative endometrium in 17.1%, secretory endometrium in 8.6%, and endometrial polyp in 17.1%, whereas these percentages in women with UI were 28.6%, 0%, 54.3%, and 20%, respectively. Conclusion: The hysteroscopic evaluation alone of infertile women might not detect all probable endometrial pathologies in women with PCOS. Key words: Polycystic ovary, Hysteroscopy, Histology, Endometrium, Infertility.


2021 ◽  
Author(s):  
Khadijeh Azarbayjani ◽  
Shahideh Jahanian Sadatmahalleh ◽  
Negin mirzaie ◽  
Nadia Jahangiri ◽  
malihe Nasiri ◽  
...  

Abstract Background: Polycystic Ovarian Syndrome (PCOS) is a common hormonal disorder that affects approximately 5-20% of women of childbearing age. Physical and psychological changes caused by PCOS might impair women’s sexual function. Infertility is one of the most important complications that may be seen in women with PCOS. This study aimed to compare sexual function in fertile and infertile women with PCOS diagnosis.Method: This cross-sectional study was conducted on 364 fertile and 239 infertile women that diagnosed with PCOS according to the Rotterdam criteria from May 2018 to February 2019. All participants were asked to fill out included demographic survey and Female Sexual Function Index (FSFI) questionnaires.Result: The mean total FSFI score in fertile and infertile women was 23.70±6.26 and 24.65±4.04, respectively. With regard to FSFI, the differences between the two groups were not statistically significant in terms of total FSFI score, desire, lubrication, satisfaction, and arousal score (P>0.05). However, the pain score, was significantly higher in the fertile group. (3.51±1.27, 3.10±1.11, P<0.001). Conclusion: Impaired sexual function in infertile women diagnosed with PCOS can be more associated with PCOS-related complications and other concurrent factors that affects sexual function rather than infertility. It seems that the effects of infertility on sexual function can be different in infertile women according to each person's condition. Hence, screening for sexual dysfunction in women with PCOS and infertility should be deemed as a part of clinical assessment, leading to early diagnosing and improving their quality of life.


2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S54-S54
Author(s):  
M Naeem

Abstract Introduction/Objective Endocrinopathies are a commonly occurring entity, particularly those of the thyroid gland, however there is lack of scientific literature from Afghanistan, a country with very limited health care facilities and resources. This is the first study aimed to describe the frequency of occurrence and factor associated with thyroid dysfunction in Afghan population. The aim of this study is to estimate the frequency and to identify factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan. Methods/Case Report A cross-sectional study was conducted from July to Sep 2018 at the Department of Clinical Pathology, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan. Blood samples were obtained, serum TSH levels were analyzed, and the patients were divided into three diagnostic categories according to their serum TSH concentrations: 1) Hypothyroidism 2) Hyperthyroidism 3) normal. Results (if a Case Study enter NA) A total of 127 individuals were included in the final analysis. Majority study participants (77%) were females. A large number of the participants (92%) did not have family history of thyroid dysfunction. (74%) participants in the study had normal TSH levels classified as normal thyroid function, (14%) had lower TSH levels and (12%) higher TSH levels (Table 1) classified as hyper and hypothyroid respectively. Conclusion The findings of the current study showed a high frequency of thyroid dysfunctions from a single center. Further large scale studies are needed to find out the prevalence and document this entity for better health outcomes in the country.


2020 ◽  
pp. 111-116
Author(s):  
Doaa Noor ◽  
Rasmiyah Al-Midhachi ◽  
Ghufran jaafar ◽  
Maysoon Sharief

Background: There is a correlation between anti-mullerian hormone (AMH) and the age when it becomes undetectable during menopause. The AMH immunoassay has been widely estimated in clinical practice to assist in reproduction and infertility treatment. Objective: To investigate the normal level of serum anti-mullerian hormone (AMH) in relation to women’s age in Basra. Patients and Methods: Cross-sectional study was carried out in Basra Maternity and Child Hospital from January 2018 to September 2019. Serum AMH levels were estimated for 975 women aged 15–50 years. They were classified into 7 age groups:15–20, 20–25, 25–30, 30–35, 35–40, 40–45 and 45–50 years. Serum AMH and FSH levels were determined by commercial enzyme-linked immunoassay. Results: Negative relationship was noticed between AMH concentration and age. The mean AMH levels for the age groups 1, 2, 3, 4, 5, 6 and 7 were 4.9 ng/ml, 4.25ng/ml, 3.27 ng/ml, 2.43ng/ml, 2.17ng/ml, 1.95ng/ml and 0.9ng/ml respectively. Conclusions: This study recorded normal levels of AMH in women in Basra. These levels can be considered for the medical treatment of infertile women. Keywords: age, anti-mullerian hormone, FSH.


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