scholarly journals Frequency and Factors associated with Thyroid Dysfunction- A Descriptive Cross-Sectional Study from a Tertiary Care Center in Afghanistan

Author(s):  
Mohammad Naeem Lakanwall ◽  
Sibtain Ahmed Ahmed ◽  
Shabnam Azizi ◽  
Jamshid Jalal ◽  
Ahmed Maseh Haidary ◽  
...  

Abstract Objective: Endocrinopathies are a commonly occurring entity, particularly those of the thyroid gland, however there is death of scientific literature from Afghanistan, a country with very limited health care facilities and resources. This is the first study aimed to describe the frequency of occurrence and factor associated with thyroid dysfunction in Afghan population. The aim of this study is to estimate the frequency and to identify factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan.Methods: A cross-sectional study was conducted from July to Sep 2018 at the Department of Clinical Pathology, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan. Blood samples were obtained, serum TSH levels were analyzed, and the patients were divided into three diagnostic categories according to their serum TSH concentrations: 1) Hypothyroidism 2) Hyperthyroidism 3) normal.Results: A total of 127 individuals were included in the final analysis. Majority study participants (77%) were females. A large number of the participants (92%) did not have family history of thyroid dysfunction. (74%) participants in the study had normal TSH levels classified as normal thyroid function, (14%) had lower TSH levels and (12%) higher TSH levels (Table 1) classified as hyper and hypothyroid respectively.Conclusion: The findings of the current study showed a high frequency of thyroid dysfunctions from a single center. Further large scale studies are needed to find out the prevalence and document this entity for better health outcomes in the country.

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S54-S54
Author(s):  
M Naeem

Abstract Introduction/Objective Endocrinopathies are a commonly occurring entity, particularly those of the thyroid gland, however there is lack of scientific literature from Afghanistan, a country with very limited health care facilities and resources. This is the first study aimed to describe the frequency of occurrence and factor associated with thyroid dysfunction in Afghan population. The aim of this study is to estimate the frequency and to identify factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan. Methods/Case Report A cross-sectional study was conducted from July to Sep 2018 at the Department of Clinical Pathology, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan. Blood samples were obtained, serum TSH levels were analyzed, and the patients were divided into three diagnostic categories according to their serum TSH concentrations: 1) Hypothyroidism 2) Hyperthyroidism 3) normal. Results (if a Case Study enter NA) A total of 127 individuals were included in the final analysis. Majority study participants (77%) were females. A large number of the participants (92%) did not have family history of thyroid dysfunction. (74%) participants in the study had normal TSH levels classified as normal thyroid function, (14%) had lower TSH levels and (12%) higher TSH levels (Table 1) classified as hyper and hypothyroid respectively. Conclusion The findings of the current study showed a high frequency of thyroid dysfunctions from a single center. Further large scale studies are needed to find out the prevalence and document this entity for better health outcomes in the country.


2021 ◽  
Author(s):  
Mohammad Naeem ◽  
Sibtain Ahmed ◽  
Ahmed Maseh Haidary ◽  
Ramin Saadaat ◽  
Ambreen Gowani ◽  
...  

Abstract Background: Endocrinopathies are a commonly occurring entity, particularly those of the thyroid gland, however there is lack of scientific literature from Afghanistan, a country with very limited health care facilities and resources. This is the first study aimed to describe the frequency of occurrence and factor associated with thyroid dysfunction in Afghan population. The aim of this study is to estimate the frequency and to identify factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan.Methods: A cross-sectional study was conducted from July to Sep 2018 at the Department of Clinical Pathology, French Medical Institute for Mothers and Children (FMIC), Kabul, Afghanistan. Blood samples were obtained, serum TSH levels were analyzed, and the patients were divided into three diagnostic categories according to their serum TSH concentrations: 1) Hypothyroidism 2) Hyperthyroidism 3) normal.Results: A total of 127 individuals were included in the final analysis. Majority study participants (77%) were females. A large number of the participants (92%) did not have family history of thyroid dysfunction. (74%) participants in the study had normal TSH levels classified as normal thyroid function, (14%) had lower TSH levels and (12%) higher TSH levels (Table 1) classified as hyper and hypothyroid respectively.Conclusions: The findings of the current study showed a high frequency of thyroid dysfunctions from a single center. Further large scale studies are needed to find out the prevalence and document this entity for better health outcomes in the country.


2019 ◽  
Vol 35 (1) ◽  
Author(s):  
Muhammad Rafiq Afridi Khalid Saifullah Baig Omer Nasim, Salman Khan

Correspondence to: Omer Nasim Ophthalmology Unit Rehman Medical Institute (RMI), Peshawar Email: [email protected] Purpose: To assess the frequency of different eye morbidities in the patients presenting at a tertiary care Hospital in Peshawar. Study Design: Cross sectional study. Place and Duration of Study: Ophthalmology unit of Rehman Medical Institute (RMI), Peshawar from February 2004 to month of March 2014. Material & Methods: This research involved accessing the data bank kept by the Hospital. All ocular morbidities seen during the study period was included in the study while those who presented with the diseases of the eye due to some other systemic condition were excluded. Patients were categorized according to their gender and year of admission. The age categories were divided into 5 groups, 0-20, 21-40, 41-60, 61-80, 81-100 years’ category. The data collected was analyzed using MS Excel 2013. Results: A total of 1869 patients were examined out of which 49.92% were male and 50.07% were female. The ocular examination revealed that out of the 1869 patients, 57.30% of the patients suffered from Cataract, 4.86% patients suffered from Pterygium, 4.76% suffered from Strabismus, 1.65% patients suffered from Glaucoma and the remaining 31.43% suffered from various spectrum of diseases. Female preponderance was more than males in the sense of general morbidity of ocular disorders.


Pharmacy ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 219
Author(s):  
Rishabh Sharma ◽  
Manik Chhabra ◽  
Kota Vidyasagar ◽  
Muhammed Rashid ◽  
Daniela Fialova ◽  
...  

Background: Older patients with type 2 diabetes mellitus (T2DM) are at greater risk of receiving potentially inappropriate medications (PIM) during hospitalization which may result in adverse outcomes. Aim: To evaluate the extent of PIM use in the older population with T2DM during hospitalization in a tertiary care hospital in India. Methods: A cross-sectional study was carried out from August 2019 to January 2020 in a tertiary care teaching hospital among the older population (aged ≥ 65 years) hospitalized with T2DM. Medications prescribed during hospitalization were reviewed following Beers Criteria 2019 to identify the extent of polypharmacy and PIM use. Binary logistic regression was applied to determine the factors associated with PIM use. Results: The mean age of the 150 patients hospitalized with T2DM was 68.85 ± 5.51 years, most of whom were men (54.7%). The participants had at least four comorbidities and were receiving an average of nine medications per day; the median length of hospital stay was 8 days (interquartile range (IQR): 4–19 days). Overall, three quarters (74%) of the participants had at least one PIM prescribed during their hospitalization as per Beers Criteria. Significant factors associated with the use of PIM during hospitalization are patients taking a higher number of medications (odds ratio (OR): 7.85, 95% CI 1.49–41.10), lower creatinine clearance values (OR: 12.90, 95% CI 2.81–59.28) and female patients (OR: 2.29; 95% CI: 1.05–4.97). Conclusions: PIM use is frequently observed in older T2DM patients during hospitalization. Polypharmacy, reduced renal function and female gender are associated with higher PIM use. Engaging clinical pharmacists in evaluating medication appropriateness can improve the outcomes of older patients.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ishara P. Premathilake ◽  
Praveena Aluthbaduge ◽  
Channa P. Senanayake ◽  
Renuka Jayalatharachchi ◽  
Sirithilak Gamage ◽  
...  

2015 ◽  
Vol 32 (4) ◽  
pp. 206-210
Author(s):  
Farzana Deeba ◽  
Parveen Sultana ◽  
Shiuly Chowdhury ◽  
Parveen Fatima ◽  
Jesmin Banu ◽  
...  

Aim: To evaluate the thyroid status in infertile women.Materials and methods: A cross sectional study was conducted in the department of Infertility of Bangabandhu Shaekh Mujib Medical University from January 2012 to December 2012. A total 400 patients of infertility were studied. The thyroid function status of the subjects were assessed and analyzed.Results: Of the 400 women enrolled for the study, 221(55%) patients with primary infertility and 179 (45%) patients were with secondary subfertility. The mean age of the responders were 22.3±4.6 years, the mean duration of marriage were 4.5±1.2 years and mean BMI were 23.2±3.1 kg/m2.Among the 400 patients 70.50% that is 293 patients were euthyroid, TSH level was increased in 23% or in 92 subjects. Depending upon the TSH levels, hypothyroid infertile women were further subdivided into subclinical hypothyroidism where TSH 4–6 mIU/L with normal FT4 (9-24 pmol/L) and clinical hypothyroidism where TSH > 6 mIU/L with raised FT4 level. It was found that 66 (71.74%) of hypothyroid infertile women were with subclinical and remaining 26 (28.26%) were with clinical hypothyroidism.Hyperthyroidism that is low TSH level (<.5 mIU/L) found in 15(3.75%) subjects and visible goiter was present in only 2 patients. In 96 hypothyroid infertile females, the mean TSH levels were 7.34 ± 2.13 mIU/L, and mean FT4 level was 17.34±3.23pmol/L. The mean PRL levels were 52.46 ±11.17 ng/ml.Conclusion: Thyroid dysfunction is an important factors for infertility. Early diagnosis and timely intervention can reduce the burden of infertility due to thyroid dysfunction.J Bangladesh Coll Phys Surg 2014; 32: 206-210


BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e035951
Author(s):  
Saja S Al-Otmy ◽  
Abeer Z Abduljabbar ◽  
Rajaa M Al-Raddadi ◽  
Fayssal Farahat

ObjectivesTo explore magnitude and factors associated with non-urgent visits to the emergency department (ED) in a tertiary care centre, western Saudi Arabia.DesignA cross-sectional study.SettingED of a tertiary care hospital in western Saudi Arabia.Participants400 patients, both men and women.InterventionsAn interview-based questionnaire was administered to a consecutive sample of patients who visited the ED during morning shifts, where primary healthcare centres (PHCs) and outpatient clinics were available.Primary outcome measureED visits classified as non-urgent versus urgent (excluding life-threatening conditions) based on the Canadian Triage and Acuity Scale (CTAS). Levels IV and V were classified as non-urgent.ResultsMajority of the cases were adult (97.3%) and half of them were women (54.8%). Non-urgent visits represented 78.5% among non-life-threatening cases. One-third of the patients (33.8%) had three visits or more to the ED during the past year. Main reasons for visiting the ED were perception that the condition was urgent (42.0%), easy access (25.5%) and limited resources and services at the PHCs (17.8%). Patients 40–50 years old were more likely to have non-urgent visits (OR=3.21, 95% CI 1.15 to 8.98). However, likelihood of non-urgent visits was significantly lower among patients with cancer (OR=0.37, 95% CI 0.19 to 0.72) and cardiovascular disease (OR=0.43, 95% CI 0.23 to 0.83), and those who live near the hospital (OR=0.49, 95% CI 0.28 to 0.88).ConclusionsThe current study reported overuse of the ED. Enhancement of the primary care services, in concordance with community awareness, is an important component to reduce burden due to non-urgent use of the ED.


Author(s):  
Swati Singh ◽  
Anil Kumar Malhotra

Background: Worldwide rise in caesarean delivery (CD) rates during the last three decades has been a cause of alarm. The rates of such delivery have increased dramatically in recent years from 12% in 1990 to 24% in 2008. Tertiary care centers have high caesarean section rates but areas where health care facilities are not available may have maternal deaths due to lack of C-section facilities. The present study was conducted to determine the prevalence of caesarean section, to assess the association between caesarean section with socio-demographic determinants and maternal risk factors.Methods: Cross-sectional study was conducted during January 2016 to April 2016. A total of 288 pregnant females admitted in obstetric ward of medical college Jhansi formed the study population, a simple random sampling technique was adopted for the study. A study tool was pre-designed and pre-tested interview schedule. The data collected was entered in MS excel and analyzed using SPSS 24 version.Results: The study showed that 73 (25.34%) of our study participants have delivered by caesarean section. Caesarean section was significantly associated with literacy, place of residence, education status, socio-economic status and occupation of the husband. Caesarean section was significantly associated with maternal risk factors like obesity, pregnancy induced hypertension, gestational diabetes mellitus and polyhydromnios.Conclusions: Present study found a high caesarean section rate as compared to the WHO standard. Utilization of antenatal care, better doctor patient communication, doctor’s commitment to reduce the rate of LSCS, may help to reduce the increasing rate of caesarean delivery.


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