scholarly journals Vitamin D3 – does it correlate with exercise tolerance in stable COPD?

2019 ◽  
Vol 14 (1) ◽  
pp. 14-20
Author(s):  
Samia Hassan ◽  
Taskina Ali ◽  
Kazi Saifuddin Bennoor ◽  
Md Ali Hossain ◽  
Mustafizur Rahman ◽  
...  

Background: Though the classic function of vitamin D3 in skeletal health is established, but its new role has been discovered in tissues and organs other than bones. Vitamin D3 deficiency has been found in patients with various morbid conditions, such as cardiovascular diseases, autoimmune diseases, infectious diseases, Diabetes mellitus and malignancies including respiratory ailments. Objectives: This cross sectional study was designed to evaluate the status of this fat soluble vitamin D3 and its correlation with exercise tolerance in stable COPD patients. Methods: For this purpose, 47 male, smoker (>4 pack years), stable (who has not experienced any acute exacerbation, hospitalizations, urgent care visits, or changes in routine medications within 4 weeks prior to study), COPD patients (post bronchodilator FEV1/FVC<0.70; duration >4 years) of >40 years of age, were selected from the Out Patient Department of National Institute of Diseases of Chest and Hospital (NIDCH), Dhaka. For the assessment of vitamin D3 status, their serum 25-hydroxycholecalciferol [25(OH)D], for exercise tolerance, 6 min walk distance [6MWD; by 6 min walk test], peripheral capillary oxygen saturation (SpO2) [by pulse oximetry], level of dyspnea and fatigue [by Modified BORG scale], were measured. The data were expressed as percentage and mean ±SEM and were statistically analyzed by Pearson’s correlation coefficient test, where p<0.05 was accepted as significant. Results: Out of 47 stable COPD patients, 46 (97.8%) were with serum 25(OH) D < 30 ng/ml. In addition, 6MWD was positively (p£0.05) and dyspnea (p£0.001) along with fatigue (p£0.05) score were negatively correlated with serum 25(OH)D level in these stable COPD patients. Conclusion: This study result concluded that, majority patients with stable COPD had D3 deficiency and this D3 deficiency showed significant correlation with decrement of exercise tolerance. J Bangladesh Soc Physiol. 2019, June; 14(1): 14-20

2019 ◽  
Vol 26 (01) ◽  
Author(s):  
Suresh Kumar ◽  
Arshad ◽  
Bilawal Hingorjo ◽  
Nathumal Maheshwari ◽  
Rewachand ◽  
...  

Objectives: Determination of vitamin D3 deficiency and insufficiency in clinically asymptomatic and apparently healthy young adult male. Study Design: Cross sectional study. Study setting & Duration: Department of Medicine, Layari General Hospital Shaheed Muhtrama Benazir Bhutto Medical College from March 2015 to May 2016.Subjects and Methods: A sample of 100 volunteer participants, comprising of 57 male and female was selected according to the study criteria. 5 ml venous blood was collected in disposable syringe. Blood urea, serum creatinine, serum calcium and phosphate were estimated by standard laboratory procedures. ARCHITECT I 1000 system detected the vitamin D3. Data analysis was analysed by SPSS 22.0 (USA). Results: Serum Calcium and Phosphate were noted as 8.76±1.11 and 9.20±0.2 mg/dl (P=0.036) & 3.23±0.85 and 3.25±0.80 mg/dl (P=0.71) in male and female subjects respectively. Vitamin D3 (mean± SD) in male and female was noted as 23.0±8.24 and 27.19±14.13 ng/dl (P=0.006). Vitamin D3 (mean± SD) of total study population was noted as 24.80± 11.29 ng/ml. Frequency of vitamin D3 deficiency, insufficiency and sufficiency noted in 45%, 32% and 23% respectively (P=0.0001). Conclusion: We found vitamin D3 deficiency and insufficiency in 77% of young apparently healthy and clinically asymptomatic adults


Author(s):  
Melvin K Mathews ◽  
Abubaker Siddiq ◽  
Bharathi D R

Background: Chronic obstructive pulmonary disease (COPD) is preventable and treatable disease state characterized by air flow limitation that is not fully reversible. Severity of the symptoms is increased during exacerbations. Objectives: The purpose of the study is to assess and improve the knowledge regarding COPD among study subjects. Materials and Methods: A Cross-sectional interventional study was carried out among the peoples in selected areas of the Chitradurga city for a period of six months. Result: A total 207 subjects enrolled in the study in that 155 male and 52 females. In our study mean score of post test was more (5.87±1.68) when compare to pre-test (2.63±1.46) which show significant increase in their knowledge after educating them (p=0.000). A total of 207 subjects were enrolled into the study. SPSS Software was used to calculate the statistical estimation. Paired t-test was used to detect the association status of different variables. Conclusion: The relatively good level of COPD awareness needs to be maintained to facilitate future prevention and control of the disease. This study had identified that negative illness perceptions should be targeted, so that they will not avoid patients from seeking for COPD treatment and adhere to it. Key words: Cross sectional study, Knowledge, practice, COPD.


MedPharmRes ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 34-39
Author(s):  
Thi-Hai-Yen Nguyen ◽  
Truong Van Dat ◽  
Phuong-Thao Huynh ◽  
Chi-Thuong Tang ◽  
Vinh-Chau Van Nguyen ◽  
...  

Vietnam has one of the highest multi drug resistance in Asia. Although, despite many efforts to implement the Antimicrobial Stewardship Programs (the ASP) since 2016, studies that on the implementation policy are very lacking of this program are limited. For that reason, we conducted this cross-sectional study to analyze the viewpoint of health workers (HWs) on the implementation of the ASP at some hospitals in Ho Chi Minh City (HCMC). An assessment of 234 HWs showed that the implementation of the ASP in HCMC hospitals was above average (62.7/100.0). A barrier to the implementation consisted of the deficiency in finances, guidelines for diagnosis, and specific interventions for some common infections, such as distributing current antibiogram and monitoring rate of Clostridioides difficile infections. These were the widely recognized problems in initially implementing the ASP. Although most HWs are aware of the importance of implementing the ASP (79.1%), the specific assessment has not been recorded clearly due to the numerous neutral responses. Despite the support of the leadership, the implementation still faces many difficulties and limitations, especially in 3rd and 4th class hospitals. Besides, there was a lack of wide dissemination of information on the ASP at each unit. To generalize the status of the ASP implementation, researchers should conduct qualitative and quantitative studies with a larger scale.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Mizuki Sata ◽  
Renzhe Cui ◽  
Chifa Chiang ◽  
Singeru Travis Singeo ◽  
Berry Moon Watson ◽  
...  

Abstract Background This study aimed to describe the status of alcohol consumption and drug use among young adults as well as their determinants. Methods We conducted a cross-sectional study of 356 young adults (aged 18 to 24 years) living in Palau in 2013. The prevalence of self-reported alcohol and marijuana usage were compared within and between sexes, age groups, ethnicities, and education levels. Results The proportion of current drinking was higher in people aged 21–24 than in those aged 18–20 (73.2% vs. 60.9%, p = 0.09 in men and 48.3% vs. 30.0%, p = 0.02 in women), while that of marijuana use did not differ between the age groups. The proportions of current drinking and marijuana use were higher in Palauan than in other ethnicities (current drinking: 70.6% vs. 40.6%, p = 0.005 in men and 38.8% vs. 16.6%, p = 0.04 in women; lifetime marijuana use: 80.0% vs. 52.9%, p = 0.02 in men and 56.1% vs. 30.6%, p = 0.09 in women). The proportion of frequent (3 times or more) marijuana users was higher for the lower educated than for the higher educated (62.5% vs. 32.1%, p < 0.001 in men and 33.9% vs. 24.4%, p = 0.12 in women). Conclusions Sex, age, ethnicity, and education were significant determinants of alcohol and marijuana use.


2021 ◽  
Vol 8 ◽  
pp. 237437352098148
Author(s):  
Saif Khairat ◽  
Xi Lin ◽  
Songzi Liu ◽  
Zhaohui Man ◽  
Tanzila Zaman ◽  
...  

Urgent care (UC) is one of the fastest growing venues of health care delivery for nonemergent conditions. This study compared the patient experience during virtual and in-person urgent care visits. We conducted a cross-sectional study of patients with the same diagnosis during Virtual Urgent Care (VUC) and in-person UC visits with the same diagnosis with regard to time and cost over a period of one year. We recorded and analyzed 16 685 urgent care visits: In-person UC (n = 14 734), VUC (n = 1262). Significant differences were found in the average total time for a visit in an in-person UC (70.89 minutes), and VUC (9.38 minutes). The average total cost of VUC ($49) and in-person UC ($142.657) differed significantly. Significant difference was found between UC turnaround time and VC turnaround time (Dependent variable (DV): 53.77, P < .01). We found significant differences in cost and time between in favor of virtual visits. Our findings suggest additional policy reform to expand the use of virtual care among target populations to improve access, reduce costs, meet the needs of patients, and reduce emergency department visits.


2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S120-S120
Author(s):  
G O Yeabyo

Abstract Introduction/Objective Cancer is one of a great public health problem in developing countries like Ethiopia and scarcity of histopathology laboratory is another burden for diagnosis and follow up of cancer diseases. The main purpose of this study is to evaluate the accessibility of histopathology services in Ethiopia. Methods Cross sectional study design were used to analyze the status of histopathology services in Ethiopia. Results There are 13 histopathology laboratories in the nation and a survey was conducted at these institutions. Out of these 13 Histopathology services seven are located in the capital, Addis Ababa and six found out of the capital located in four different regions. About 40,239,100 habitants have no histopathology service around their catchment area. Conclusion There are very limited histopathology laboratories, as a result diagnosis and prevention of cancer diseases are inadequate throughout the country.


2019 ◽  
Vol 37 (4) ◽  
pp. 459-467 ◽  
Author(s):  
Hanna Sandelowsky ◽  
Ingvar Krakau ◽  
Sonja Modin ◽  
Björn Ställberg ◽  
Anna Nager

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Anshul Saxena ◽  
Muni Rubens ◽  
Sankalp Das ◽  
Tanuja Rajan ◽  
Gowtham Grandhi ◽  
...  

Objectives: Extensive data suggests that lesbian, gay and bisexual (LGB) adults are more likely to experience adverse cardiovascular outcomes relative to heterosexuals. However, evidence regarding cardiovascular health (CVH) disparities and sexual orientation is scarce. The aim of this study was to examine the distribution of CVH metrics in a US nationally representative population of heterosexual (HT), and LGB adults. Methods: This cross-sectional study analyzed 2445 participants (representing 115 million) adults aged 18 or over years in the 2011-2012 NHANES survey. The CVH factors of smoking, body mass index (BMI), physical activity (PA), diet, blood pressure (BP), total cholesterol (TC) and glucose (GLU) were measured. Each CVH factor was then classified as ideal; intermediate; or poor. Ideal CVH was defined as presence of >=5 ideal CVH metrics. Results: 95.1% of the weighted sample self-identified as HT (95% CI: 93.5%, 96.6%) compared to 4.9% (95%: 3.3%, 6.5%) LGB. The figure illustrates the distribution of each of the 7 CVH categories according to sexual orientation. In age, gender, and race adjusted analysis, LGB individuals were 36% (AOR: 0.64; 95%: 0.29, 1.4; p > 0.05) less likely to have ideal CVH compared to HT. These proportions go higher after adjusting for age. Conclusions: The results suggest that LGB individuals face a higher risk of being in the category for poor cardiovascular health compared to heterosexuals. Evidence suggests that there are sexual orientation disparities among adults. If confirmed in other studies, results point towards disproportionately higher risk for cardiovascular disease among sexual-minority populations. Figure


2018 ◽  
Vol 4 (1) ◽  
pp. 20-32 ◽  
Author(s):  
D. Mishra ◽  
J. Lamichhane

Background: Sexual harassment on public transport is an everyday occurrence for millions of girls and women around the globe. With the skyrocketing population of Kathmandu valley public transport has been facing enormous pressure. The major victims of these harassments happens to be college going girls and working women as they tend to travel more in public transports. This study sought to determine the prevalence and factors responsible for sexual harassment in public transport among female health science students.Methods: A descriptive cross-sectional study was carried out among 396 female health science students studying in Manmohan Memorial Institute of Health Sciences using self-administered structured questionnaire. Participants were selected through stratified random sampling method.Results: The prevalence of sexual harassment among female health science students was found to be 79.6%. Physical harassment was the most prominent type of harassment (67.1%) followed by verbal (61.2%) and non verbal 34.6%. After the experience of sexual harassment, 44.6% scolded the harasser, 29.1% kept silent, 17.3% dropped at nearest bus station whereas remaining 9% reacted in other different ways. Overcrowding was considered as main reason for sexual harassment by 69.2% of the participants. 36.8% of female students didn’t use any precautionary methods whereas 32.6% avoided going out alone at night.Conclusion: The study reveals that the prevalence of sexual harassment is significantly high. With increasing population and limited vehicles people are left with no option rather than travelling in the overcrowded vehicles where the chances of experiencing various sorts of sexual harassments are very high. In order to address this emerging issue, prompt and appropriate intervention should be taken by government, public and especially the status of women must be raised in society.JMMIHS.2018;4(1):20-32


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