scholarly journals Prevalence of Periodontitis among Rheumatoid Arthritis Patients Attending Tertiary Hospital in Nepal

2020 ◽  
Vol 17 (4) ◽  
pp. 543-547
Author(s):  
Sweta Shrestha ◽  
Shaili Pradhan ◽  
Binod Adhikari
Keyword(s):  
Rheumatoid Arthritis ◽  
Tertiary Hospital ◽  
Periodontal Pocket ◽  
Pocket Depth ◽  
Female Ratio ◽  
Severe Periodontitis ◽  
Set Up ◽  
Male To Female ◽  
Host Inflammatory Response ◽  
Pro Inflammatory Cytokines

Background: Rheumatoid arthritis and Periodontitis both are chronic destructive inflammatory disorders characterized by dysregulation of the host inflammatory response and increase in localized and systemically circulating pro-inflammatory cytokines. The objective of this study was to determine prevalence of periodontitis among Rheumatoid Arthritis patients in our setup.Methods: A crossectional study was done in 43 cases of diagnosed Rheumatoid Arthritis patients visiting to department of Orthopedics of Bir Hospital during the period of July 2016 to January 2017 were examined for presence of periodontitis and its severity. A descriptive questionnaire was also prepared concerning age, sex, personal history. Parameters to be measured were Plaque Index, Gingival Index, Pocket Depth and Clinical Attachment Level.Results: Prevalence of periodontitis among Rheumatoid Arthritis patients was found to be 86.04% (37) with Mild periodontitis in 9%(4), Moderate periodontitis 56% (24)and severe periodontitis in 21% (9). The commonest age group was 50.41±9. with male to female ratio of 1:3Conclusions: Periodontitis was common in Rheumatoid Arthritis in our set up. Moderate periodontitis was more frequent. Periodic oral examination of patients with Rheumatoid Arthritis is required to improve periodontal health.Keywords: Host response; inflammation; periodontal pocket depth; periodontitis; pgingivalis rheumatoid arthritis.

scholarly journals Ascitic Fluid Cytology Seen in a Tertiary Hospital in Nigeria

2020 ◽  
pp. 345-350
Author(s):  
CC Nwafor ◽  
K Obioha ◽  
TO Akhiwu
Keyword(s):  
Sex Ratio ◽  
Patient Care ◽  
Ascitic Fluid ◽  
Age Groups ◽  
Tertiary Hospital ◽  
Age Group ◽  
Malignant Cells ◽  
Female Ratio ◽  
Male To Female ◽  
Fluid Cytology

Ascites is a symptom that can originate due to diverse pathologies. A lot of investigations including ascitic fluid cytology (AFC) can be done on it to help determine its origin. The aim of this study, is to document the findings and highlight the importance of AFC in patient care in Uyo. All AFC reports and slides in the Department of Histopathology, University of Uyo were retrieved, reviewed and used for this study. The age ranged from 1.5 – 80 years with mean age, 41.79 (±17.23) years. About 71.8% of the ascitic fluid (AF) specimens were from patients between the 3rd and 6th decade. Females predominated in all age groups expect 10-19 year's group, with a male to female sex ratio of 1:2.4. Malignant cells were seen in 28.7% of all the samples, while 51.2% were negative for malignant cells. Malignant cells were seen in 4 (6.7%), 11 (18.3%) and 6 (10%) of the AFC performed due to various liver pathologies, ovarian malignancies and intra-abdominal malignancies respectively. Malignant cells were found more in females with a male to female ratio of 1: 3.6. Age group 40-49 years accounted for most of the malignant cases (26.6%). The pattern of AFC in Uyo is similar to the pattern in other parts of Nigeria

scholarly journals Investigation of Salivary RANKL and OPG Levels in Periodontitis Patients at Hospital Universiti Sains Malaysia

2021 ◽  
Author(s):  
Saba Asif ◽  
Basaruddin Ahmad ◽  
Syed Ameer Hamza ◽  
Haslina Taib ◽  
Nur Karyatee Kassim ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Periodontal Pocket ◽  
Pocket Depth ◽  
Cross Sectional ◽  
Plaque Score ◽  
Mean Values ◽  
Severe Periodontitis ◽  
Whole Saliva ◽  
Elisa Technique ◽  
Unstimulated Whole Saliva

Abstract Background This study was aimed to determine the levels of salivary receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG) and its association with periodontal status among periodontitis patients. Patients and Methods A cross-sectional study was designed and performed at the Dental Clinic, Hospital Universiti Sains Malaysia (HUSM). Random sampling was employed to identify 88 participants into three groups: 30 mild periodontitis, 30 moderate to severe periodontitis, and 28 healthy (nonperiodontitis) patients. Periodontal parameters: periodontal pocket depth (PPD), clinical attachment level (CAL), plaque score (PS), and gingival bleeding index (GBI) were recorded. In total, 4 mL of unstimulated whole saliva was collected to determine the levels of salivary RANKL and OPG proteins by using ELISA technique. Data were analyzed by using SPSS software version 24.0. Results Mean values for PPD (5.3 ± 0.5) and CAL (5.6 ± 0.5) were observed higher for moderate to severe periodontitis as compared with values (4.4 ± 0.2) (4.5 ± 0.2) in mild periodontitis patients. The mean salivary RANKL and OPG was 0.23 ± 0.07 ng/mL and 1.78 ± 0.70 ng/mL respectively in moderate to severe periodontitis. Only salivary RANKL levels were significantly and positively correlated with all the clinical periodontal parameters. Conclusion The levels of salivary RANKL were higher as opposed to lower OPG levels in periodontitis patients in contrast to healthy (nonperiodontitis) patients. RANKL levels were significantly associated with the periodontal parameters. Therefore, we can conclude that RANKL can potentially aid as an adjunctive diagnostic protein in evaluating periodontal disease.

Non-Surgical Periodontal Therapy Decreases Periodontal Pocket Depth and Clinical Attachment Loss of Rheumatoid Arthritis Patients

2021 ◽  
Vol 15 (11) ◽  
pp. 3376-3377
Author(s):  
Marryam Riaz ◽  
Sohaib Shujaat ◽  
Ayesha Fahim ◽  
Shamail Zafar ◽  
Mariyah Javed ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Gingival Recession ◽  
Periodontal Therapy ◽  
Periodontal Pocket ◽  
P Value ◽  
Pocket Depth ◽  
Clinical Attachment Loss ◽  
Public And Private ◽  
Attachment Loss ◽  
Before And After

Objective: The objective of the present study was to determine the effect of non-surgical periodontal therapy on the disease severity in rheumatoid arthritis patients. Methods: Five hundred and twenty arthritis patients were included in the study, using consecutive non-probability sampling from the outpatient department of various public and private hospitals of Pakistan. Patients with periodontitis along with systemic Rheumatoid Arthritis (RA) were included in the study. Clinical parameters taken for the severity of periodontitis were the Gingival recession (GV), Periodontal Pocket Depth (PPD) and Clinical Attachment Loss (CAL). Independent sample t-test was used for significance before and after non-surgical periodontal therapy. Data was presented with mean (standard deviation). Results: The PPD and CAL of Rheumatoid Arthritis patients were found to be decreased significantly following non-surgical periodontal treatment (p value < 0.05), unlike the gingival recession, which did not decrease significantly (p value > 0.05). Conclusion: The PPD and CAL values of periodontal patients with rheumatoid arthritis were significantly reduced after giving non-surgical Periotherapy along with oral hygiene instruction. Keywords: arthritis; gingiva; periodontitis; periodontal pocket

scholarly journals Spectrum of Central Nervous System Tumours in a Tertiary Hospital of Bangladesh

2019 ◽  
Vol 20 (1) ◽  
pp. 34-37
Author(s):  
SM Khodeza Nahar Begum ◽  
Masud Parvez ◽  
Mohammad Raziul Hoque ◽  
Omid Khan ◽  
Rita Rani Barua ◽  
...  
Keyword(s):  
Adult Population ◽  
B Cell Lymphoma ◽  
Tertiary Hospital ◽  
Female Ratio ◽  
Intracranial Germinoma ◽  
Central Nervous System Tumours ◽  
Astrocytic Tumours ◽  
Spinal Cord Tumours ◽  
Set Up ◽  
Intracranial Epidermoid

Background: Tumour registry data on intracranial and intraspinal tumours from a newly set up tertiary hospital of Bangladesh is presented here to provide substantial information about the current trends. Materials & methods: Hospital records of patients admitted under the neurosurgery service between January 2016 upto December 2017 were evaluated. Causes with a principal diagnosis of brain and spinal cord tumours were identified. Diagnosis with WHO grading and the histological subtypes are recorded. Results: 86 cases of various tumours were retrieved out of total 98 neurosurgical cases. 70 of these tumours were of intracranial origin and 16 of intraspinal origin. Male to female ratio was approximately 1.28:1. The mean age of the patients was 45.9 years (range 3-75 years). Paediatric and adult patients accounted for 12.6% and 87.4% respectively. Most of the tumours were found in the 6th decade. Paediatric intracranial tumours were predominately by medulloblastoma while adult population showed highest incidence of astrocytic tumours. Some rare entities were also encountered such as intracranial germinoma, Diffuse large B cell lymphoma (DLBCL) and squamous cell carcinoma in a pre-existing intracranial epidermoid cyst. Conclusions: Distribution of CNS tumour among this population gives a glimpse of the prevalence rate of such tumours in our community. This data can be linked to other national and international tumour registry for improved therapeutics and research. J MEDICINE JUL 2019; 20 (1) : 34-37

scholarly journals Periodontal disease in ideal weight, overweight and obese patients in different gender of a Tertiary Care Hospital in Pakistan.

2019 ◽  
Vol 26 (09) ◽  
pp. 1461-1465
Author(s):  
Zaheer Hussain Chachar ◽  
Gotam Das ◽  
Shabir Ahmed ◽  
Maimuna Khokhar ◽  
Muhammad Ilyas Shaikh ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Normal Weight ◽  
Periodontal Pocket ◽  
Care Hospital ◽  
Obese Patients ◽  
Ideal Weight ◽  
Pocket Depth ◽  
Female Ratio

Introduction: Chronic periodontitis is the inflammation of the gingiva extending into the supporting structure of teeth. Periodontal disease is characterized by loss of clinical attachment due to destruction of the periodontal ligament and loss of the adjacent supporting bone eventually leading to tooth loss. Obesity is unusual or unnecessary fat deposition that may harm health. A number of hypotheses for biological reactions among obesity and periodontal disease have been anticipated. Objectives: To determine the frequency of ideal weight, overweight and obese patients in dental outdoor of FMH Pakistan. Study Design: Cross-Sectional Study. Setting:  Medical Outdoor at Tertiary Care Hospital in Pakistan. Period: 15th January to 14th July 2017. Material & Methods: A total 100 patients came to the medical outpatients department between 25 to 45 years of age were included. Patients satisfying the inclusion criteria, subjects BMI score were checked by classifying him/her obese, overweight or normal weight. Periodontal pocket depth was observed by WHO probe of one tooth from each male and female patient. Frequency of periodontal disease was seen in subjects. Results: Age range in his study was from 25 to 45 years with mean age of 36.9 ±7.51 years. In 100 patients 66 (66%) were females & 34 (34%) were males and with male to female ratio 1.9:1. Periodontal disease was seen in 47 female patients (71%) and in 24 male patients (70%). Pocket depth was present in over weight and obese patients more than normal weight. Conclusion: current study accomplished that there is positive association of periodontal disease in overweight and obese patients. The incidence of periodontal disease was highest in female obese patients.

scholarly journals Effects of statins as local drug delivery agents in treating chronic periodontitis and their antimicrobial effects using polymerase chain reaction

2020 ◽  
Vol 3 ◽  
pp. 82-88
Author(s):  
Ritunja Singh ◽  
Gangesh B. Singh ◽  
Soumya Gupta ◽  
Anil Agrawal
Keyword(s):  
Chronic Periodontitis ◽  
Periodontal Pocket ◽  
Pocket Depth ◽  
Female Ratio ◽  
Clinical Attachment Level ◽  
Antimicrobial Effects ◽  
Intergroup Comparison ◽  
Anti Inflammatory ◽  
Root Planning ◽  
Attachment Level

Objectives: The aim of the study was to evaluate the anti-inflammatory effect of statin medication in chronic periodontitis patients and to compare the change in periodontal probing depth and clinical attachment level using 1.2% atorvastatin (ATV) gel and scaling and root planning (SRP) compared to SRP alone. Materials and Methods: This study was carried out on a sample size of 40 patients with equal male and female ratio between the age group of 40–60 years having chronic periodontitis with a minimum of 20 teeth that were selected for the study. Bilateral quadrants were selected and a split mouth study was conducted. Supragingival scaling was carried out in each patient in one long appointment. The patient was then recalled after 1 week for subgingival SRP. Root planing was carried out in two consecutive visits. Left side of the mouth on the 1st day followed by right side of the mouth on the next day. On the 2nd day, after completion of the root planning, followed by placement of 1.2% ATV gel and finally the Coe Pak was placed in one quadrant which was called the test site. In the other quadrant which was called control site placebo gel was placed and the treated site was covered by the Coe Pak. The recording of clinical parameters (plaque index [PI], gingival index [GI], probing pocket depth, and clinical attachment loss) was done at baseline, 1 month and 3 months. The selected site was sampled for subgingival microflora. The data obtained were subjected to statistical analysis. One-way ANOVA, Tukey’s HSD test, and student t-test were used for intergroup and intragroup comparison. Results: In our study, when intergroup comparison of mean value for PI at baseline, 1 month and 3 months was found to clinically insignificant for control and test groups, while for GI, periodontal pocket depth, and clinical attachment level it was found insignificant at baseline while significant at 1 and 3 months. Similarly, when comparison was made for microbial count it was found clinically insignificant between control and test group at baseline, while significant was noted at 3-month interval. Conclusion: Our study evaluated the anti-inflammatory, osteoconductive and antimicrobial effects of atorvastatin giving significant reduction in PI, GI, PPD and gain in CAL along with significant decrease in the microbial load.

scholarly journals Inter personal violence-related facial injuries: a 10-year survey

2018 ◽  
Vol 24 (1) ◽  
pp. 2-5 ◽  
Author(s):  
Toua Antoine Coulibaly ◽  
Rasmané Béogo ◽  
Ibraïma Traoré ◽  
Héra Michel Kohoun ◽  
Biévianda Vincent Ili
Keyword(s):  
Interpersonal Violence ◽  
Soft Tissues ◽  
Dental Trauma ◽  
Tertiary Hospital ◽  
Female Ratio ◽  
Facial Injuries ◽  
The Face ◽  
Limb Fractures ◽  
Male To Female ◽  
Zygomatic Fractures

Introduction: Interpersonal violence (IPV) has emerged as a worldwide health problem affecting predominantly the face. Patients and methods: This study reports the characteristics of violence, victims and injuries in IPV-related facial injuries patients, in a 10-year survey, in a tertiary hospital of Burkina Faso. Results: Patients’ age ranged from 11 to 75 years (mean 31 years) and 58.2% of the patients were aged between 20 and 39 years. There were 74 males and females 24 giving a male-to-female ratio of 3.1:1. The circumstances of injuries were brawls (80.6%) consisting mostly in facial blows, and hold-ups (19.4%). Fractures involving predominantly the mandible or the zygomatic complex were the most common injury, accounting for 53.2%. Soft tissues injuries accounted for 37.2% and dental trauma for 9.2%. In 27.5% of the patients, extra facial injuries were encountered, dominated by cerebral trauma and limb fractures. Conclusion: In this study, IPV-related facial injuries are mostly mandibular or zygomatic fractures in young and males adults involved in brawls. These findings command strategies for prevention of violence in this specific group.

scholarly journals Common Site of Urinary Calculi in Kidney, Ureter and Urinary Bladder Region: Jos Experience

2019 ◽  
Vol 7 (10) ◽  
Author(s):  
Samuel Moses Danjem ◽  
Salaam AJ ◽  
Kolade- Yunusa HO ◽  
Shuaibu SI
Keyword(s):  
Urinary Bladder ◽  
Urinary Calculi ◽  
Renal Stones ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Common Location ◽  
The Common ◽  
Male To Female

Objective: To determine the common location of calculus along the urinary tract using CT scan.  Methods: This cross sectional study was conducted using CT from November 2016 to September 2018, in a tertiary hospital in Jos, Nigeria. The CT images acquired from this period were evaluated and 50 patients were positive for urolithiasis. The data was subjected to statistical analysis based on age, gender and calculus location. Results: Out of the 50 patients with calculi, 34 were males and 16 were females with a male to female ratio of 2.13:1. 137 urinary calculi were documented in which 90 were in males and 47 in the female patients. Highest occurrence of calculi was seen in age group 31-40 years (34.0%). 112(82%) were renal stones, 12(9%) were ureteric stones, 8(6%) were found in pelvi-ureteric junction (PUJ), 3(2%) were in the vesico-ureteric junction (VUJ), 2(1%) were in the urinary bladder and none in the urethra. Conclusion: Kidney stones are the most common followed by the ureter, the pelvi-ureteric junction, the vesico-ureteric junction and the bladder.  

scholarly journals Subsidence in Collarless Corail Hip Replacement

2015 ◽  
Vol 9 (1) ◽  
pp. 194-197 ◽  
Author(s):  
Veenesh Selvaratnam ◽  
Vishwanath Shetty ◽  
Vishal Sahni
Keyword(s):  
Rheumatoid Arthritis ◽  
Revision Surgery ◽  
Hip Replacement ◽  
X Rays ◽  
Indications For Surgery ◽  
Retrospective Case ◽  
Female Ratio ◽  
X Ray ◽  
Male To Female

The purpose of this study was to assess whether subsidence occurs in collarless Corail hip replacement (CCHR) and to ascertain the extent and timing of subsidence if present. Retrospective case notes analysis was performed. Sixty eight patients who had CCHR were identified from our database. Male to female ratio was 32:36. Their mean age was 74.2 years (range 37-95 years). Indications for surgery were osteoarthritis in 64 (94%) patients, rheumatoid arthritis in two (3%) patients and avascular necrosis in two (3%) patients. Subsidence was measured at 6 weeks, 6 months and 1 year post-op compared to initial post-op x-rays. At 6 weeks x-ray 21 patients did not have any subsidence, 18 patients had 1 millimeter (mm) subsidence, 10 patients had 2mms subsidence, 4 patients had 3mms subsidence, 5 patients had 4mms subsidence, 1 patient had 5mms subsidence, 4 patients had 6 mms subsidence and 1 patient each had subsidence of 7mms, 9mms, 11mms, 13mms and 26 mms respectively. When compared with 6 months x-rays only 2 patients had a further subsidence of 2mms while another patient had 3mms subsidence. No further subsidence occurred at 1 year follow up x-rays. One patient had revision surgery due to symptomatic subsidence (29mms) at 6 months follow up. Subsidence does occur in the first 6 weeks in collarless Corail hip replacement, and to a lesser extent until 6 months postoperatively, but does not progress further.

scholarly journals Implications of Ultrasonography in the Diagnosis and Management of Patients Presenting with Non-Traumatic Acute Abdominal Pain in a Tertiary Hospital of Mid-Western Region of Nepal

2018 ◽  
Vol 8 (2) ◽  
pp. 30-34
Author(s):  
Prasanna Ghimire ◽  
Nabin Paudel ◽  
Dwight Koirala ◽  
Bhuwaneshwar Prasad Singh
Keyword(s):  
Acute Abdomen ◽  
Acute Abdominal Pain ◽  
Tertiary Hospital ◽  
Common Finding ◽  
Exclusion Criteria ◽  
Female Ratio ◽  
Female Predominance ◽  
Common Etiology ◽  
A Prospective Study ◽  
Male To Female

Introduction: Acute abdomen is the most common condition for patients presenting in the emergency. Ultrasound among other imaging modalities is the most common diagnostic tool employed in the diagnosis of such cases.Methods: A prospective study of consecutive patients presenting with acute abdomen fulfilling the inclusion and exclusion criteria were included in the study. Ultrasound was performed by single radiologist and findings were correlated to the clinical, pathological and surgical findings.Results: A total of 248 patients fulfilled all criteria and were included in the study. The age of patients ranged from 15-62 years with mean age of 41.3 years. There was female predominance with a male to female ratio of 1:1.8. Ultrasound accurately diagnosed 233 cases (93.9 %). Urolithiasis was the most common finding (45.16%) followed by acute appendicitis (19.35%).Conclusion: Ultrasound has pivotal role in the diagnosis and overall management of patient presenting with acute abdomen. Urolithiasis is the most common etiology for non- traumatic acute abdomen.

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